[Hub]/) : Traits : Lung FVC :

chr20:46,838,455-48,603,940

Best TWAS P=1.18e-09 · Best GWAS P=2.16e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ARFGEF2 0.09 0.05 lasso 8 0.10 9.2e-13 6.5 -5.4 5.5e-08 -0.82 0.00 1.00 FALSE
2 GTEx Esophagus Mucosa ZFAS1 0.15 0.01 enet 16 0.01 8.9e-02 5.4 5.7 1.1e-08 0.69 0.06 0.79 FALSE
3 GTEx Skin Sun Exposed Lower leg ZFAS1 0.07 0.03 enet 14 0.05 5.8e-05 5.5 5.5 5.0e-08 0.77 0.17 0.77 FALSE
4 GTEx Testis ARFGEF2 0.20 0.20 lasso 7 0.24 5.4e-11 3.8 -5.4 8.0e-08 -0.91 0.02 0.98 FALSE
5 METSIM Adipose ARFGEF2 0.04 0.03 lasso 12 0.02 9.8e-05 6.7 -6.1 1.2e-09 -0.98 0.02 0.98 TRUE
6 NTR Blood SNORD12B 0.03 0.05 lasso 8 0.05 1.9e-14 5.5 -5.8 4.9e-09 -0.96 0.06 0.94 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma ARFGEF2 0.05 0.04 lasso 5 0.05 3.2e-06 6.5 -5.8 6.4e-09 -0.94 0.00 1.00 FALSE
8 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C20orf199 0.05 0.06 lasso 4 0.06 1.0e-04 5.5 5.5 5.0e-08 0.92 0.01 0.95 FALSE