Best TWAS P=4.96e-20 · Best GWAS P=4.35e-20 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | MAP2 | 0.10 | 0.06 | lasso | 12 | 0.08 | 1.7e-06 | -9.2 | 8.5 | 2.0e-17 | -0.88 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Esophagus Muscularis | MAP2 | 0.15 | 0.11 | lasso | 2 | 0.10 | 9.6e-07 | -9.2 | 9.2 | 5.0e-20 | -1.00 | 0.00 | 1.00 | TRUE |
| 3 | GTEx | Lung | MAP2 | 0.09 | 0.04 | enet | 11 | 0.06 | 3.0e-05 | -7.6 | 8.5 | 1.6e-17 | -0.83 | 0.06 | 0.92 | FALSE |