Best TWAS P=6.44e-08 · Best GWAS P=3.83e-19 conditioned to 1.89e-16
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | TMBIM1 | 0.09 | 0.00 | enet | 85 | 0.01 | 0.0454 | -2.9 | 5.4 | 6.4e-08 | -0.07 | 0.13 | 0.08 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | DIRC3 | 0.03 | 0.01 | blup | 275 | 0.01 | 0.0014 | -4.4 | -5.2 | 1.6e-07 | 0.07 | 0.65 | 0.01 | TRUE |