Best TWAS P=1.38e-15 · Best GWAS P=9.1e-09 conditioned to 0.79
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | CUL3 | 0.04 | 0.01 | blup | 498 | 0.01 | 0.0076 | -5.7 | -8.0 | 1.4e-15 | 0.74 | 0.01 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CUL3 | 0.04 | 0.01 | blup | 91 | 0.02 | 0.0052 | -5.3 | -5.4 | 5.4e-08 | 0.81 | 0.01 | 0.78 | FALSE |