Best TWAS P=2.24e-08 · Best GWAS P=9.84e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | RP11-395N3.2 | 0.10 | 0.02 | lasso | 3 | 0.01 | 1.1e-01 | 5.1 | 5.3 | 9.3e-08 | 0.82 | 0.08 | 0.58 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | RHBDD1 | 0.07 | 0.07 | enet | 8 | 0.08 | 1.4e-10 | 5.7 | -5.6 | 2.2e-08 | -0.96 | 0.04 | 0.96 | TRUE |
| 3 | YFS | Blood | COL4A4 | 0.08 | 0.14 | lasso | 8 | 0.16 | 3.2e-48 | 5.1 | -5.4 | 7.7e-08 | -0.95 | 0.04 | 0.96 | FALSE |