Best TWAS P=3.56e-10 · Best GWAS P=4.65e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | SLMAP | 0.06 | 0.05 | lasso | 4 | 0.05 | 0.00052 | 6.6 | 6.3 | 3.6e-10 | 0.98 | 0.02 | 0.96 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | DNAH12 | 0.04 | 0.00 | blup | 448 | 0.02 | 0.00103 | 4.2 | 6.1 | 1.0e-09 | 0.41 | 0.18 | 0.09 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SLMAP | 0.01 | 0.01 | blup | 86 | 0.01 | 0.00911 | 6.6 | 6.1 | 9.1e-10 | 0.98 | 0.02 | 0.85 | FALSE |