[Hub]/) : Traits : Lung FVC : ← →

chr1:25,752,617-27,595,862

Best TWAS P=1.21e-09 · Best GWAS P=2.78e-08 conditioned to 0.212

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Cells Transformed fibroblasts	DHDDS	0.13	0.09	lasso	4	0.08	1.0e-06	5.5	-5.5	2.9e-08	-0.99	0.01	0.99	FALSE
2	GTEx	Esophagus Mucosa	DHDDS	0.11	0.06	lasso	4	0.04	6.6e-04	-4.5	-5.5	2.9e-08	-0.60	0.08	0.87	FALSE
3	GTEx	Nerve Tibial	PDIK1L	0.09	0.01	enet	10	0.03	2.2e-03	5.2	-5.3	1.3e-07	-0.21	0.09	0.88	FALSE
4	GTEx	Pituitary	CNKSR1	0.38	0.16	lasso	7	0.15	1.4e-04	4.7	-5.4	7.9e-08	-0.26	0.22	0.35	FALSE
5	GTEx	Skin Not Sun Exposed Suprapubic	CNKSR1	0.15	0.10	lasso	7	0.09	1.0e-05	4.7	-5.2	1.6e-07	-0.27	0.34	0.63	FALSE
6	GTEx	Skin Sun Exposed Lower leg	DHDDS	0.21	0.14	lasso	1	0.12	5.5e-10	5.5	-5.5	3.6e-08	-1.00	0.01	0.99	FALSE
7	GTEx	Skin Sun Exposed Lower leg	PDIK1L	0.14	0.05	enet	23	0.12	3.1e-10	4.8	-5.6	2.4e-08	-0.17	0.24	0.76	TRUE
8	METSIM	Adipose	RPS6KA1	0.04	0.01	bslmm	367	0.03	3.9e-05	4.5	5.2	1.8e-07	0.54	0.17	0.80	FALSE
9	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	TRIM63	0.03	0.02	blup	33	0.02	4.6e-03	4.8	5.5	4.5e-08	0.25	0.02	0.73	FALSE
10	The Cancer Genome Atlas	Colon Adenocarcinoma	TRIM63	0.08	0.10	lasso	4	0.10	3.7e-06	4.9	5.2	1.9e-07	0.24	0.01	0.98	FALSE
11	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PDIK1L	0.02	0.00	blup	37	0.02	1.2e-03	2.3	-5.2	1.7e-07	-0.24	0.02	0.67	FALSE
12	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	RPS6KA1	0.11	0.05	lasso	6	0.07	8.0e-04	-5.0	6.1	1.2e-09	0.59	0.03	0.54	TRUE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	DHDDS	0.04	0.00	blup	50	0.02	5.7e-03	5.5	-5.7	1.2e-08	-0.78	0.01	0.74	FALSE
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	PDIK1L	0.03	0.03	blup	37	0.02	7.0e-03	-4.0	-5.3	1.0e-07	-0.23	0.02	0.24	FALSE