Best TWAS P=7.05e-10 · Best GWAS P=7.5e-14 conditioned to 8.78e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ITGA2 | 0.11 | 0.09 | lasso | 1 | 0.07 | 1.7e-06 | 6.1 | -6.1 | 9.4e-10 | -0.66 | 0.73 | 0.16 | FALSE |
| 2 | METSIM | Adipose | ITGA2 | 0.06 | 0.04 | lasso | 6 | 0.02 | 1.9e-04 | 6.1 | -6.2 | 7.1e-10 | -0.69 | 0.05 | 0.95 | TRUE |