[Hub]/) : Traits : Lung FVC : ← →

chr5:42,321,011-44,403,631

Best TWAS P=5.7e-14 · Best GWAS P=1.63e-20 conditioned to 5.25e-14

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	PAIP1	0.04	0.05	enet	22	0.05	6.7e-07	-5.4	5.6	1.9e-08	0.01	0.99	0.01	FALSE
2	GTEx	Adrenal Gland	NNT	0.17	0.15	lasso	4	0.07	1.3e-03	5.4	-5.6	2.2e-08	-0.08	0.59	0.09	FALSE
3	GTEx	Adrenal Gland	C5orf34	0.16	0.00	lasso	4	0.02	5.0e-02	5.4	-5.6	2.3e-08	-0.04	0.05	0.14	FALSE
4	GTEx	Artery Aorta	NNT	0.10	0.00	enet	30	0.01	1.5e-01	-2.6	-7.5	5.7e-14	-0.27	0.10	0.07	TRUE
5	GTEx	Brain Caudate basal ganglia	C5orf34	0.14	-0.01	enet	14	0.00	3.3e-01	-5.4	-6.8	1.4e-11	-0.06	0.13	0.12	FALSE
6	GTEx	Brain Frontal Cortex BA9	PAIP1	0.13	-0.01	enet	25	0.02	1.1e-01	3.0	-7.0	2.1e-12	-0.06	0.06	0.23	TRUE
7	GTEx	Cells Transformed fibroblasts	NNT-AS1	0.08	0.04	lasso	5	0.05	7.8e-05	-5.4	5.6	1.8e-08	0.08	0.80	0.06	FALSE
8	GTEx	Cells Transformed fibroblasts	RP11-159F24.3	0.05	0.01	enet	11	0.02	8.4e-03	-5.1	-6.9	5.5e-12	-0.08	0.11	0.14	FALSE
9	GTEx	Esophagus Mucosa	C5orf34	0.05	0.05	enet	9	0.02	9.8e-03	-5.4	-5.5	4.7e-08	-0.05	0.62	0.04	FALSE
10	GTEx	Esophagus Muscularis	NNT	0.17	0.07	enet	27	0.11	2.7e-07	-2.5	-6.3	2.3e-10	-0.19	0.98	0.00	FALSE
11	GTEx	Muscle Skeletal	NNT	0.23	0.07	enet	32	0.21	1.5e-20	-5.4	-5.6	2.3e-08	-0.12	0.99	0.01	FALSE
12	GTEx	Muscle Skeletal	NNT-AS1	0.05	0.04	lasso	1	0.03	6.6e-04	-5.4	-5.4	7.9e-08	-0.04	0.36	0.02	FALSE
13	GTEx	Spleen	C5orf34	0.28	0.23	lasso	5	0.24	6.2e-07	-5.4	-5.4	6.8e-08	-0.06	0.81	0.02	FALSE
14	GTEx	Thyroid	C5orf34	0.08	0.08	lasso	3	0.06	1.4e-05	-6.8	-7.2	4.5e-13	-0.02	0.04	0.94	FALSE
15	GTEx	Whole Blood	C5orf34	0.07	0.01	lasso	4	0.04	3.1e-04	-5.4	-5.6	2.0e-08	-0.12	0.72	0.02	FALSE
16	GTEx	Whole Blood	CTD-2201E18.3	0.08	0.00	lasso	5	0.02	1.0e-02	6.2	6.2	6.1e-10	0.08	0.05	0.06	TRUE
17	METSIM	Adipose	C5orf34	0.04	0.04	lasso	5	0.04	3.9e-07	-5.4	-5.1	2.9e-07	-0.05	0.99	0.01	FALSE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C5orf34	0.11	0.12	enet	13	0.11	2.9e-12	-5.4	-5.3	1.4e-07	-0.08	0.90	0.10	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PAIP1	0.02	0.03	lasso	1	0.03	2.5e-04	-5.4	5.4	8.6e-08	0.02	0.09	0.16	FALSE
20	The Cancer Genome Atlas	Lung Adenocarcinoma	C5orf34	0.04	0.03	blup	39	0.03	1.5e-04	-5.4	-5.3	1.1e-07	-0.07	0.87	0.11	FALSE
21	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C5orf34	0.30	0.02	enet	14	0.06	2.2e-07	-5.4	-5.9	4.4e-09	-0.11	0.01	0.94	FALSE
22	The Cancer Genome Atlas	Thyroid Carcinoma	C5orf34	0.04	0.02	blup	39	0.02	2.5e-03	-5.3	-5.9	4.5e-09	-0.02	0.17	0.26	FALSE