TWAS hub - ITGA2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1960	0.0380	2.0e-10	0.065	0.087	0.144	0.127	0.132	2.2e-08	1.1e-10	3.7e-17	3.3e-15	8.9e-16
2	GTEx	Adipose Subcutaneous	0.1080	0.0400	2.4e-03	0.086	NA	0.038	NA	0.072	1.6e-07	NA	4.4e-04	NA	1.7e-06
3	GTEx	Artery Aorta	0.1480	0.0490	5.1e-04	-0.004	NA	0.000	NA	-0.005	6.9e-01	NA	3.4e-01	NA	7.9e-01
4	GTEx	Artery Tibial	0.1448	0.0406	4.0e-06	0.057	NA	0.076	NA	0.069	3.0e-05	NA	1.5e-06	NA	4.5e-06
5	GTEx	Cells Transformed fibroblasts	0.0660	0.0280	6.3e-03	0.014	NA	0.003	NA	0.019	2.7e-02	NA	1.8e-01	NA	1.2e-02
6	GTEx	Esophagus Mucosa	0.1240	0.0430	8.2e-04	0.125	NA	0.080	NA	0.110	1.1e-08	NA	4.9e-06	NA	9.1e-08
7	GTEx	Esophagus Muscularis	0.1820	0.0560	4.7e-04	0.027	NA	0.075	NA	0.076	8.5e-03	NA	2.4e-05	NA	2.3e-05
8	GTEx	Heart Left Ventricle	0.1977	0.0578	1.6e-04	0.199	NA	0.137	NA	0.169	7.6e-11	NA	9.2e-08	NA	2.5e-09
9	GTEx	Lung	0.1718	0.0432	5.7e-07	0.212	NA	0.163	NA	0.200	3.5e-16	NA	1.7e-12	NA	2.8e-15
10	GTEx	Prostate	0.2850	0.1020	4.4e-03	-0.010	NA	-0.012	NA	-0.011	7.1e-01	NA	8.9e-01	NA	7.4e-01
11	GTEx	Skin Not Sun Exposed Suprapubic	0.1350	0.0500	4.3e-03	-0.002	NA	0.005	NA	-0.004	4.4e-01	NA	1.7e-01	NA	6.4e-01
12	GTEx	Testis	0.2250	0.0720	2.9e-04	0.117	NA	0.100	NA	0.139	7.7e-06	NA	3.3e-05	NA	9.6e-07
13	METSIM	Adipose	0.0603	0.0236	2.6e-03	0.041	0.005	0.015	0.013	0.023	7.3e-07	4.9e-02	2.0e-03	4.1e-03	2.0e-04
14	YFS	Blood	0.0288	0.0090	1.0e-06	0.028	0.025	0.022	0.025	0.028	1.2e-09	1.3e-08	9.6e-08	1.1e-08	1.0e-09
15	TCGA	Head and Neck Squamous Cell Carcinoma	0.0364	0.0170	1.3e-03	0.008	0.016	0.020	NA	0.011	3.8e-02	6.3e-03	2.4e-03	NA	1.9e-02
16	TCGA	Brain Lower Grade Glioma	0.0797	0.0282	1.9e-06	0.019	0.058	0.030	NA	0.035	2.9e-03	3.4e-07	2.3e-04	NA	7.3e-05
17	TCGA	Pheochromocytoma and Paraganglioma	0.2710	0.1110	6.0e-03	0.044	0.022	0.065	NA	0.029	7.7e-03	4.4e-02	1.5e-03	NA	2.4e-02
18	TCGA	Prostate Adenocarcinoma	0.1150	0.0492	5.4e-04	0.016	0.033	0.045	NA	0.037	7.2e-03	1.8e-04	1.6e-05	NA	9.3e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Basal cell carcinoma (self-reported)	4.6	5.5	21.8	0.5	1.0	-0.2	-2.7	2.9	2.5	0.5	-2.5	-2.0	2.9	2.2	4.1	1.1	4.7	2.0	2.8	-0.1	0.4
Lung FEV1/FVC ratio	4.3	22.0	60.8	-1.8	-5.9	-7.0	-6.1	5.4	3.5	-4.0	-7.0	-7.8	1.5	1.3	1.4	-5.8	6.4	5.0	0.7	0.3	-0.1
Average weekly spirits intake	2.7	3.4	9.3	-1.6	-0.8	0.4	1.2	-3.0	-2.6	-1.6	0.9	0.4	-1.9	-3.0	-1.8	-0.8	-2.7	-2.1	-2.4	-0.6	-1.1
Medication for hormone replacement therapy	2.7	3.0	10.3	0.3	-1.1	-0.4	-1.4	3.2	2.5	-1.0	-1.8	-1.7	0.7	2.9	0.0	-1.0	2.5	2.0	0.9	2.1	0.9
Pain type(s) experienced in last month: Hip pain	2.3	2.9	9.5	-1.4	-1.8	-1.2	0.6	-2.0	-2.4	-2.0	-0.1	-0.4	-1.7	-0.7	-2.4	-1.8	-2.4	-1.0	-3.1	0.8	-1.4
Type 2 Diabetes (T2D) (2012)	2.2	2.5	10.9	1.9	2.8	-0.5	0.5	0.1	-0.3	-0.2	0.4	-0.2	3.3	-1.3	1.1	2.9	0.1	-2.2	0.9	-0.5	-2.3
Medication: Co-codamol	2.2	2.5	6.9	2.6	1.4	1.9	2.2	1.5	1.7	2.1	1.4	2.2	0.5	1.0	0.3	1.4	1.1	0.7	2.3	1.3	0.8
Ulcerative Colitis	2.0	2.9	9.3	-2.1	-1.6	-2.0	-2.8	1.0	0.5	-2.3	-3.0	-2.7	0.6	0.0	0.6	-1.6	1.5	0.5	-1.1	-1.4	-0.9
Relative age voice broke	2.0	3.1	18.6	0.8	-0.5	4.3	2.4	0.2	0.5	1.3	1.7	2.3	-0.2	1.8	-1.6	-0.7	-0.4	2.0	1.0	2.1	2.0
Chronic bronchitis/emphysema (father)	2.0	2.3	7.7	0.2	2.8	2.3	0.7	-1.1	-1.0	1.5	1.5	1.2	1.3	-1.4	0.8	2.7	-0.5	-1.7	1.0	-1.6	-1.5
Alcohol usually taken with meals	2.0	3.2	9.0	-2.8	-3.0	-0.9	-2.1	-0.7	-0.8	-2.5	-2.3	-1.7	-1.4	-0.2	-0.9	-3.0	-0.3	0.9	-2.3	-1.6	0.1
Medication: Lansoprazole	2.0	2.3	5.5	-0.3	-2.1	1.1	1.5	-1.3	-2.3	-1.6	0.3	0.0	-2.3	-1.5	-2.1	-2.0	-2.0	-0.3	-1.6	0.1	0.1
Lung FVC	1.9	9.6	38.0	-2.4	-6.1	-0.9	-3.3	2.8	1.2	-2.8	-4.3	-4.1	0.3	0.7	0.1	-6.2	4.0	3.2	-0.6	-0.2	1.1
Breastfed as a baby	1.9	2.4	5.0	-0.2	-2.0	-1.9	-2.0	-0.6	-1.9	-2.0	-2.2	-2.2	-0.4	-0.0	0.0	-1.7	-0.5	-2.1	-1.0	-2.0	0.0
Osteoarthritis (self-reported)	1.9	2.5	10.6	-0.7	-3.2	0.3	-0.6	1.4	0.8	-1.9	-2.3	-1.4	1.1	1.1	-1.4	-3.2	1.8	1.1	-0.6	-0.1	-0.2
Pack years of smoking	1.9	2.8	7.9	-1.5	-1.5	-2.0	-0.8	-2.1	-2.8	-1.7	-1.3	-1.5	-1.0	-1.9	-0.8	-1.5	-0.8	-1.1	-2.4	-1.8	-1.9
Forced expiratory volume in 1-second (FEV1)	1.8	5.9	15.7	-1.4	-3.6	-1.4	-2.6	2.5	1.5	-2.8	-3.6	-4.0	1.0	0.5	1.3	-3.4	3.7	2.3	-0.4	1.6	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.7	5.5	16.8	-1.7	-4.1	-0.9	-1.9	2.2	1.4	-3.3	-2.9	-3.7	0.0	0.1	0.2	-4.0	3.2	2.4	-0.5	1.7	0.5
Length of working week for main job	1.7	1.9	8.1	0.4	-0.4	0.1	0.8	1.4	2.4	1.4	0.6	1.3	0.5	2.8	-1.7	-0.6	0.2	2.5	1.3	0.8	0.8
Supplements: Vitamin C	1.7	2.0	7.2	-1.5	-0.4	-1.2	-2.4	0.4	-0.4	-1.1	-2.6	-2.7	-0.5	-0.6	1.7	-0.3	1.4	0.4	-0.4	-1.0	-1.9
Average weekly red wine intake	1.7	2.5	10.7	-3.3	-1.1	-0.9	-1.7	-1.6	-1.3	-1.9	-1.4	-1.4	-0.7	-1.3	0.5	-1.3	-0.0	-0.0	-2.1	-1.7	-2.3
Medication: Atenolol	1.6	2.0	6.7	2.5	0.9	-1.6	-0.5	2.2	1.6	0.7	-0.5	-1.4	0.9	-0.2	1.4	1.0	1.9	0.7	2.6	1.3	0.1
High blood pressure (mother)	1.6	2.2	8.1	0.8	-0.7	0.6	0.3	2.7	2.4	0.8	-0.1	0.1	-1.0	2.0	-0.0	-0.7	1.5	2.8	1.8	1.6	1.5
Illnesses of siblings	1.6	2.2	6.0	0.2	1.3	1.5	1.1	-2.1	-1.5	-0.1	2.4	1.8	-2.2	-1.0	-0.7	1.4	-2.4	-1.3	-1.0	1.4	0.6
Smoking status: Previous	1.6	2.4	6.8	-1.8	0.3	-0.6	-0.9	-1.1	-1.0	-1.9	-1.8	-1.6	2.6	-1.2	1.4	0.3	0.5	-2.2	-1.1	-1.9	-2.4
Medication for cholesterol	1.6	2.4	9.2	-1.2	0.7	-0.4	1.6	-3.0	-1.4	0.6	2.2	2.3	-0.5	-1.3	-1.1	0.5	-2.5	-1.1	-1.9	-1.0	-0.2
Primary Biliary Cirrhosis	1.5	2.1	7.3	0.1	0.2	0.6	-1.2	1.8	0.9	0.6	-1.4	-2.2	2.4	-1.0	2.7	0.3	2.6	1.3	1.3	0.4	0.5
Pack years adult smoking proportion	1.5	2.2	5.9	-1.5	-1.2	-1.7	-0.3	-2.1	-2.4	-1.4	-0.9	-1.3	-1.0	-1.9	-0.8	-1.2	-1.0	-0.8	-2.4	-1.2	-1.7
High blood pressure (siblings)	1.5	2.1	6.4	-1.0	-1.4	-0.7	-1.6	2.4	2.0	-0.2	-2.5	-1.9	0.7	0.4	0.8	-1.5	2.1	1.9	0.6	-1.0	-0.3
Had major operations	1.5	1.8	6.6	-0.8	-1.0	-1.6	-1.9	-0.2	-1.5	-1.4	-1.8	-2.6	0.6	-1.2	0.9	-0.9	0.8	-1.5	-0.6	-1.4	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	7.3	-0.1	0.8	2.7	1.0	-0.0	0.2	2.2	2.0	1.5	-0.8	2.0	-0.1	0.7	-0.4	1.0	1.1	0.3	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.4	2.9	14.2	0.4	-3.8	-0.3	0.8	1.9	1.6	-1.1	-0.6	-1.0	-0.8	0.2	-1.9	-3.8	1.1	2.2	0.7	1.4	1.2
Respiratory disease	1.3	2.9	11.0	-1.2	1.4	-0.3	0.3	-2.8	-2.0	-1.2	1.0	-0.0	0.1	-0.9	0.2	1.5	-2.1	-3.3	-2.1	-1.9	-2.9
Hand grip strength (left)	1.3	3.4	13.7	-1.0	-3.6	1.5	-0.1	1.5	1.8	-1.0	-1.1	0.1	-0.4	2.4	-2.2	-3.7	0.5	2.8	-0.6	0.6	2.1
Hearing difficulty/problems with background noise	1.3	2.1	6.8	-0.6	0.3	-2.2	-2.2	1.0	1.3	-0.1	-1.4	-2.4	2.6	0.8	2.5	0.3	1.5	0.4	0.2	-0.3	-1.0
Time employed in main current job	1.3	1.5	5.8	1.4	-1.6	1.1	-0.0	1.4	0.2	0.1	-0.4	0.1	-2.2	-0.1	-1.4	-1.6	1.0	2.4	0.6	1.8	0.7
Neck or shoulder pain in last month	1.3	1.8	5.1	-0.7	-0.1	-2.3	-2.2	-0.3	-1.5	-1.0	-1.7	-2.3	0.8	-1.2	1.4	-0.0	0.5	-1.4	-1.6	0.1	-1.5
Medication: Seretide 50 evohaler	1.3	1.5	5.3	0.9	2.3	-0.2	0.4	-0.8	-1.2	1.9	1.4	0.7	-0.7	-0.6	1.5	2.3	-0.7	-0.9	0.9	-0.6	-1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.5	6.1	-1.3	0.4	1.1	0.8	-1.9	-2.5	-0.8	0.8	0.9	-0.3	-1.7	-0.6	0.3	-1.0	-1.8	-1.8	-0.5	-1.0
Average weekly champagne plus white wine intake	1.3	1.8	8.7	-0.4	-1.9	-0.6	-1.3	0.9	1.0	0.0	-1.6	-0.7	-1.0	1.9	0.4	-1.8	0.5	1.9	-1.0	0.1	3.0
Average weekly beer plus cider intake	1.3	1.8	6.1	2.5	1.4	2.1	1.6	0.9	1.3	1.7	1.1	1.1	1.1	1.0	0.4	1.3	0.7	0.0	2.1	0.6	0.9
Blood White Count	1.2	9.0	28.2	3.1	2.6	3.0	5.3	-2.5	-2.0	3.1	5.2	3.9	-1.1	-3.1	-1.8	2.6	-3.9	-2.6	1.3	0.4	1.2
Average weekly fortified wine intake	1.2	1.4	5.4	-1.4	-0.6	-1.5	-2.3	-0.6	-0.7	-0.3	-1.4	-1.4	0.6	-1.4	2.0	-0.6	0.2	-0.1	-1.2	-1.7	0.2
Diabetes (self-reported)	1.2	1.8	8.7	-0.8	-0.0	-1.4	-1.1	0.2	-1.0	-0.2	-1.4	-2.1	0.7	-2.9	1.8	-0.1	1.8	-0.3	0.6	-1.6	-1.6
Hair/balding pattern: Pattern 3	1.2	1.7	5.1	1.7	-0.2	2.2	2.1	-1.1	-1.1	1.1	1.8	1.0	-2.3	-1.2	-0.9	-0.2	-1.4	-0.8	0.5	0.3	1.0
Happiness	1.2	1.5	6.5	-2.1	-2.0	-0.7	-0.4	-0.9	-0.4	-1.4	-1.0	-0.5	-0.7	-0.4	-0.6	-2.0	-0.8	1.1	-2.5	0.2	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.5	7.2	-0.1	2.2	-0.4	-1.4	-0.5	-0.2	1.9	0.1	-0.4	1.4	0.9	2.7	2.1	1.2	-0.1	0.7	-0.0	-0.0
Migraine (self-reported)	1.2	1.5	5.1	0.4	1.9	-1.5	-1.0	0.7	0.7	0.8	-0.3	-0.5	2.3	0.7	1.7	2.0	1.5	0.4	0.9	0.5	-1.1
Number of full sisters	1.2	1.5	5.5	-0.8	2.0	-1.2	-0.5	-1.2	-0.2	0.7	0.4	0.5	1.6	0.3	1.1	2.0	-1.2	-1.6	-0.4	-2.4	0.1
Diabetes diagnosed by doctor	1.2	2.0	8.6	-0.6	-0.1	-1.5	-1.4	0.2	-1.2	-0.2	-1.7	-2.5	0.6	-2.9	1.8	-0.1	1.4	-0.2	0.5	-1.5	-1.8
Guilty feelings	1.2	1.7	5.6	-1.0	-2.1	2.4	0.8	-1.0	-0.8	-0.3	0.5	0.3	-1.4	-0.6	-1.7	-2.2	-1.9	0.6	-1.6	1.0	-0.4
Fasting Glucose	1.1	1.3	7.3	-0.7	-0.6	0.4	0.4	-0.9	-2.1	-0.8	-0.8	-1.8	-0.6	-2.7	-0.4	-0.5	0.4	-1.0	-1.4	-0.7	-0.4
Lupus	1.1	1.6	6.7	-0.1	-1.1	-0.2	1.1	-1.2	-0.8	-1.4	1.1	0.7	-1.9	-0.1	-2.2	-1.0	-2.6	-1.3	-1.2	-1.2	0.1
Rheumatoid Arthritis	1.1	1.6	5.9	-1.0	-2.4	-0.3	-1.1	0.6	0.0	-1.7	-1.4	-1.3	-1.8	0.1	-0.2	-2.4	0.9	1.3	-1.3	0.2	0.4
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.5	9.5	0.2	-2.1	2.2	1.7	-0.9	-1.5	-0.4	1.4	1.4	-2.3	0.3	-3.1	-2.1	-2.2	-0.4	-0.7	0.6	0.2
Past tobacco smoking	1.1	2.0	8.9	1.4	-1.0	-0.1	-0.2	1.2	1.1	0.9	0.7	0.7	-3.0	1.7	-1.4	-1.0	-0.2	2.2	0.5	1.6	2.4
Mouth/teeth dental problems: Dentures	1.1	1.9	10.8	0.5	0.0	-0.2	0.4	-1.6	-2.6	1.0	0.8	0.7	-0.4	-3.3	-0.0	0.0	-0.6	-2.0	-0.1	-2.4	-0.5
Emphysema/chronic bronchitis	1.1	1.2	5.6	-1.1	-0.9	-1.6	-1.3	-0.3	-0.7	-0.3	-1.3	-1.3	0.5	0.1	1.5	-0.8	0.7	-1.2	-0.5	-2.4	-0.1
Knee pain experienced in last month	1.1	1.6	6.2	-0.7	-1.8	-0.7	-0.7	-0.1	-0.8	-2.5	-2.3	-1.3	-1.1	-0.1	-0.7	-1.8	0.9	-0.1	-1.9	0.7	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.3	8.2	0.4	0.7	1.0	2.9	-1.5	-1.3	-0.7	2.1	1.1	-2.0	-1.3	-1.3	0.8	-2.1	-1.3	-1.0	2.5	0.6
Risk taking	1.1	1.7	4.9	-1.9	-1.2	-0.8	-1.2	-0.9	-1.3	-2.2	-1.8	-1.2	-0.4	-0.3	-0.5	-1.2	-1.0	-0.8	-2.2	-1.0	-0.9
Mean Putamen Volume	1.0	1.2	3.3	-1.8	-1.1	-0.2	-0.7	-1.4	-1.6	-1.2	-0.3	-0.9	-0.3	-1.7	-0.2	-1.1	-0.6	-0.5	-1.6	-1.4	-0.2
Neuroticism (2016)	1.0	1.5	6.1	-2.2	-1.2	0.4	-0.5	-1.4	-1.1	-1.4	-0.7	-0.8	0.1	-0.4	-0.4	-1.3	-0.7	-0.8	-2.5	0.6	-2.0
Heel T-Score	1.0	7.9	22.0	-3.0	-4.1	0.8	0.1	-2.8	-4.7	-2.2	-0.2	-1.6	-2.7	-4.2	-2.5	-4.3	-1.8	-1.2	-2.7	-2.4	-3.4
Severe depression (siblings)	1.0	1.1	3.8	-1.7	-1.0	-0.7	-1.5	0.3	0.6	-1.2	-1.6	-1.9	0.8	0.0	0.2	-1.0	0.2	0.2	-0.9	1.6	-0.4
Hand grip strength (right)	1.0	2.7	11.9	-2.1	-3.3	1.2	-0.8	0.6	1.2	-1.0	-1.5	-1.0	0.5	1.9	-0.9	-3.4	0.9	2.4	-1.2	0.1	1.2
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	5.5	-1.8	0.3	-0.1	-1.2	0.4	0.5	-0.5	-1.2	-1.3	2.4	0.1	1.7	0.2	2.1	0.2	-0.7	0.4	-1.3
Birth weight of first child	1.0	1.8	7.0	1.8	-0.1	1.3	0.8	1.1	0.8	1.2	0.9	0.8	-2.4	0.5	-1.6	-0.0	-0.1	1.9	1.1	2.6	1.3
Health satisfaction	1.0	1.3	4.3	-0.4	-1.8	-0.8	-0.3	0.1	-0.3	-0.2	-0.3	0.4	-2.1	0.7	-1.2	-1.8	-1.1	0.9	-1.7	1.2	1.6
Mouth/teeth dental problems: Loose teeth	1.0	1.2	4.7	-0.2	-1.2	-0.1	-1.0	1.3	1.0	-0.9	-1.7	-2.2	1.5	-0.5	0.8	-1.1	1.2	0.5	0.3	0.2	-1.5
Chest pain or discomfort	1.0	1.5	4.3	-1.7	-1.4	-1.5	0.1	-1.0	-0.7	-0.8	0.5	-0.1	-1.8	1.4	-2.1	-1.4	-1.6	0.3	-1.4	-0.3	-0.7
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	6.8	-1.8	-0.2	0.6	-0.2	0.9	2.6	-1.1	-0.5	-0.3	2.2	1.0	0.0	-0.4	0.6	1.1	0.6	-0.1	-0.3
Medication: Gliclazide	1.0	1.1	3.3	-0.6	1.3	-0.1	-0.8	-0.2	-0.7	1.3	-0.2	-0.4	1.2	-1.3	1.8	1.2	1.2	0.3	1.3	-1.4	-1.5
Financial situation satisfaction	1.0	1.3	4.4	-0.7	-1.0	0.8	1.5	-1.1	-0.2	-0.5	0.7	0.9	-1.8	-1.0	-2.1	-1.0	-1.6	0.7	-1.1	1.2	0.6
Medication: Atorvastatin	1.0	1.2	3.4	1.4	-0.9	0.3	1.0	-0.7	-1.1	-0.4	0.7	0.1	-1.8	-0.3	-1.4	-1.0	-1.8	-1.1	-0.1	-1.7	-1.4
Alcohol drinker status: Never	1.0	1.2	3.6	0.2	-1.1	0.2	0.4	-0.9	-1.2	-1.6	-0.6	-0.4	-1.9	-1.2	-1.1	-1.0	-0.7	-1.0	-1.5	1.6	0.7
Number of operations (self-reported)	1.0	1.4	5.9	0.2	-0.1	-1.7	-0.5	-0.9	-2.4	-0.9	-0.9	-1.2	-0.1	-1.6	0.7	-0.1	0.7	-1.6	-0.7	-1.4	-2.1
Age started oral contraceptive pill	1.0	1.3	3.7	-1.9	-1.3	0.4	-1.7	1.2	1.0	-0.5	-1.7	-1.6	0.5	0.9	0.9	-1.4	0.7	1.2	0.4	-0.6	-0.4
Alzheimer’s Disease (in mother)	0.9	1.1	4.1	2.0	0.4	1.5	1.7	-0.7	-1.1	1.3	1.2	0.8	-0.3	-1.7	0.5	0.5	-0.3	-0.0	0.5	0.9	0.5
Alzheimer’s Disease (including proxy)	0.9	1.4	3.9	1.7	0.3	1.4	2.0	-0.8	-1.0	1.9	1.7	1.6	-1.1	-1.0	-0.6	0.3	-0.8	0.4	0.0	1.1	0.9
Type 2 Diabetes (T2D) (2018)	0.9	1.7	13.0	0.0	0.5	-0.9	-0.1	-1.2	-1.8	-0.2	-0.4	-1.6	-0.2	-3.6	1.0	0.5	-0.2	-1.7	0.0	-1.5	-1.9
Relative age of first facial hair	0.9	1.9	8.6	-0.1	0.3	2.9	2.8	-0.6	-0.6	1.1	1.9	2.4	0.2	0.9	-1.4	0.1	-0.9	0.9	0.4	1.0	0.4
Ever used hormone-replacement therapy (HRT)	0.9	1.2	3.3	-0.9	0.2	0.2	-1.4	1.0	0.8	-0.1	-1.7	-1.1	1.6	1.0	1.1	0.1	1.8	1.5	0.0	0.3	-1.4
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	3.4	1.0	-0.3	-1.0	-1.1	1.8	1.1	0.2	-1.0	-0.4	1.2	1.4	0.3	-0.3	1.6	1.1	0.8	0.8	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	2.4	0.9	1.5	0.0	0.3	0.7	1.1	1.3	0.3	0.6	1.1	0.2	1.1	1.5	1.3	0.3	1.4	1.3	0.3
Illnesses of mother	0.9	1.2	3.9	0.5	1.1	0.2	0.7	0.9	1.9	0.3	1.1	1.1	2.0	0.9	-0.7	1.2	-0.0	-0.3	1.4	1.2	1.4
Peak expiratory flow (PEF)	0.9	2.1	7.2	-0.0	-1.6	-1.6	-2.1	0.7	-0.7	-2.0	-2.7	-2.7	0.7	-0.2	1.2	-1.4	1.5	-0.3	-0.4	-0.3	1.4
Loud music exposure frequency	0.9	1.0	2.2	0.8	1.2	-1.2	-0.8	1.5	1.2	0.9	-0.3	-0.5	0.5	1.2	1.4	1.3	0.7	0.4	1.1	0.5	1.2
Chronic bronchitis/emphysema (mother)	0.9	1.0	3.2	-0.8	0.4	0.9	-0.5	-1.4	-1.7	0.6	0.5	-0.3	-0.4	-1.5	0.6	0.3	-1.1	-0.8	-0.8	-1.6	-1.8
Medication for pain relief, constipation, heartburn	0.9	1.6	8.8	0.6	-0.7	-0.2	0.3	-2.0	-3.0	0.4	0.4	1.0	-2.0	-1.8	-0.9	-0.6	-1.3	-0.5	-1.1	-1.1	1.1
Heart disease (mother)	0.9	1.1	3.4	-1.9	-1.2	-0.1	-0.2	-1.0	-1.2	-0.8	-0.2	-1.0	-1.5	0.6	-0.4	-1.3	-0.7	0.1	-1.5	-0.4	-1.8
Wears glasses or contact lenses	0.9	1.0	3.1	1.1	1.4	-0.0	-0.1	1.4	1.3	1.1	-0.1	0.1	1.2	0.5	1.1	1.4	1.2	0.7	1.8	0.6	-0.6
Medication: Lisinopril	0.9	1.2	4.5	0.4	-0.1	0.5	-0.1	1.7	1.1	1.7	-0.4	-0.1	1.0	0.3	0.9	-0.2	2.1	2.1	1.3	0.9	0.9
Illnesses of father: High blood pressure	0.9	1.2	4.0	-1.0	-1.0	-0.8	-1.8	0.7	0.7	-1.9	-2.0	-1.6	-0.9	0.5	-0.4	-0.8	0.2	-0.7	-1.1	0.1	0.6
Hair/balding pattern: Pattern 2	0.8	1.0	3.2	-0.4	1.2	-1.1	-0.3	0.4	0.1	1.4	-0.0	-0.5	1.8	-0.1	1.6	1.2	1.5	0.8	1.3	0.7	-0.5
Had menopause	0.8	1.0	3.3	-1.6	-1.7	-0.3	-0.4	-0.8	-0.7	-0.9	-0.5	-0.6	-0.8	-0.5	-1.3	-1.8	-0.7	0.6	-1.7	-0.3	-0.7
Lung cancer (father)	0.8	0.9	6.1	0.4	-0.9	-2.5	-1.3	0.5	-0.2	-0.6	-1.5	-1.6	-0.7	0.8	0.1	-0.8	0.7	0.2	-0.0	-0.3	0.8
Tense / ‘highly strung’	0.8	1.3	3.5	-1.0	-1.3	0.9	-1.9	0.4	0.1	-0.8	-1.9	-1.6	-1.1	-0.9	1.3	-1.2	1.3	0.9	-1.1	1.1	0.7
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	4.8	-0.0	0.2	0.6	0.2	-1.7	-2.2	-0.2	0.6	0.2	-1.6	-1.5	-0.8	0.2	-1.8	-1.5	-1.5	-0.1	-0.5
Medication: Paracetamol	0.8	1.4	5.9	0.3	1.1	1.6	1.1	1.1	2.4	1.1	0.9	-0.2	1.5	1.1	1.1	1.0	0.6	0.8	1.5	1.4	-0.4
Exposure to tobacco smoke outside home	0.8	1.0	3.5	-0.5	0.3	-0.1	0.5	-1.7	-1.7	-0.8	0.7	0.0	-0.7	-0.3	-1.2	0.4	-1.9	-1.5	-0.9	-0.2	-1.4
Number of children fathered	0.8	0.9	3.2	-0.3	-1.0	-1.8	-0.9	1.0	0.8	-0.5	-1.3	-1.2	-0.5	0.1	0.6	-0.9	0.5	1.3	0.4	1.3	-0.1
Medication: Ibuprofen	0.8	0.9	4.8	-1.3	0.6	0.1	-0.9	0.6	0.7	-0.5	-0.7	-1.0	2.2	0.3	1.3	0.6	1.7	-0.2	-0.3	0.5	-1.1
Back pain experienced in last month	0.8	1.1	4.5	-0.8	-1.3	-0.8	-0.6	-0.2	-0.3	-1.9	-1.5	-1.4	-0.2	-0.3	-0.4	-1.3	-0.1	-0.1	-2.1	1.0	-1.4
Ever smoked	0.8	1.5	6.2	-0.7	1.6	0.6	0.5	-1.0	-0.7	0.6	-0.0	-0.1	2.5	-1.2	2.2	1.5	0.5	-1.3	0.0	-1.1	-1.7
Pain experienced in last month	0.8	1.3	4.6	0.4	0.7	-0.9	-0.4	0.9	1.0	1.8	0.5	0.3	1.3	1.1	1.0	0.7	0.3	0.5	2.2	-1.6	1.9
Bipolar Disorder (2018)	0.7	1.1	6.0	-1.6	-0.7	-2.5	-1.3	-0.0	0.8	-1.4	-0.7	-1.7	0.4	0.8	0.3	-0.7	-0.3	0.2	-0.3	0.4	-0.7
Depressed Affect (Nagel 2018)	0.7	1.5	5.5	-2.2	-0.2	-0.5	-0.4	-1.9	-1.5	-1.1	-0.5	-0.2	-0.1	-0.6	-0.1	-0.2	-1.3	-1.4	-2.3	0.0	-1.8
Major Depression (MDD)	0.7	0.8	3.0	0.6	-0.7	-1.5	-1.6	0.2	-0.4	-0.7	-1.7	-1.3	0.5	-0.4	0.6	-0.5	0.3	-0.5	0.1	-1.3	-0.2
Blood Platelet Count	0.7	8.6	20.5	3.1	4.3	4.1	4.1	-2.6	-1.8	3.2	4.5	4.3	-0.6	-0.8	0.0	4.2	-2.1	-2.9	1.2	0.5	-0.1
Ever had hysterectomy (womb removed)	0.7	0.8	4.6	0.8	-0.3	-0.1	-0.5	1.2	0.8	-0.2	-0.9	-1.0	-0.7	0.7	0.2	-0.2	-0.0	1.8	0.9	2.1	-0.1
Supplements: Zinc	0.7	0.7	4.4	-2.1	0.3	-0.2	-0.9	0.5	0.8	0.0	-0.9	-0.7	0.0	0.9	0.9	0.2	0.4	1.6	-0.5	-0.4	-0.9
Fed-up feelings	0.7	1.3	4.6	-1.9	-0.2	-0.4	0.3	-1.6	-0.4	-1.5	0.3	0.2	0.3	0.6	-0.7	-0.2	-1.9	-1.8	-2.1	0.6	-1.1
Taking other prescription medications	0.7	1.1	3.8	-0.0	0.5	-1.7	0.1	-1.0	-1.4	-0.9	-0.0	-0.4	0.3	-0.3	-0.2	0.6	-1.3	-1.9	-1.4	-1.1	-2.0
Qualifications: CSEs or equivalent	0.7	0.9	3.1	1.0	-1.0	-1.6	-0.1	1.2	0.8	-1.3	-0.9	-0.4	0.6	0.6	-0.6	-0.8	0.8	0.5	-0.2	1.8	0.4
Stomach or abdominal pain in last month	0.7	0.8	5.8	1.5	1.1	2.4	0.4	-0.2	-0.5	0.6	0.5	0.7	0.4	0.3	0.3	1.2	-0.1	-1.1	0.5	0.9	0.3
Supplements: Glucosamine	0.7	0.9	4.6	0.0	0.5	-0.5	-1.5	0.8	0.4	-0.4	-1.6	-1.0	1.0	0.3	0.9	0.5	2.1	-0.1	0.1	-1.1	-1.0
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	2.7	-1.0	-1.6	1.0	-0.7	-0.1	-0.1	-0.7	-1.2	-1.4	0.2	-0.5	-0.6	-1.6	-0.4	0.9	-0.4	0.3	-1.0
Number of incorrect matches in round	0.7	1.1	4.0	1.1	1.4	0.6	-1.3	1.1	1.1	0.6	-0.7	0.5	0.9	0.7	2.0	1.4	1.6	0.6	0.5	0.7	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	3.5	-1.8	-1.5	0.5	-0.5	-0.2	0.2	-1.8	-0.7	-1.0	-0.1	0.1	-0.9	-1.4	-0.1	0.4	-1.3	1.9	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	4.1	0.0	-1.9	1.9	1.5	-1.0	-1.7	-0.7	0.8	0.7	-1.5	-0.4	-2.0	-1.8	-1.0	-0.7	-0.8	0.7	-0.2
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	3.6	-0.5	-0.3	1.4	1.3	-0.8	-0.3	-0.7	0.7	0.3	-1.2	-1.8	-0.8	-0.4	-0.5	-0.6	-1.0	1.9	-0.9
Impedance of arm (right)	0.7	3.1	12.2	3.4	2.7	-1.4	-0.7	0.2	-0.6	0.9	0.3	-0.7	-0.6	-1.8	3.5	3.0	0.5	-1.8	1.9	-0.2	-1.4
Pulse wave Arterial Stiffness index	0.7	0.8	3.1	1.2	-0.3	1.7	0.8	1.1	0.4	0.5	0.2	0.6	0.3	0.7	-0.6	-0.2	-0.1	0.7	1.0	0.9	1.8
Pulse wave reflection index	0.7	0.9	4.1	1.1	-0.5	1.0	0.8	0.6	0.4	0.6	1.1	1.0	-1.0	-0.1	-2.0	-0.5	-1.3	0.6	0.6	0.5	1.3
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	3.1	0.8	0.2	1.2	0.9	0.5	1.8	0.3	1.2	1.3	0.4	1.0	-0.3	0.3	-0.8	1.3	0.9	1.1	0.4
Forced vital capacity (FVC), Best measure	0.7	2.6	10.9	-0.9	-3.3	1.2	0.3	0.8	0.1	-2.7	-1.0	-1.8	-0.9	-0.8	-0.8	-3.2	1.3	1.1	-0.9	2.1	1.0
Worry too long after embarrassment	0.7	1.2	3.6	1.0	0.2	1.5	1.4	-0.9	-1.3	1.4	1.9	1.2	-1.2	-0.7	-0.8	0.1	-1.5	-0.4	-0.0	0.9	-0.4
Pulse wave peak to peak time	0.7	0.8	3.2	-1.4	0.2	-1.7	-0.7	-1.3	-0.5	-0.6	-0.3	-0.6	-0.4	-0.7	0.4	0.1	0.1	-0.7	-1.2	-0.8	-1.8
Long-standing illness, disability or infirmity	0.7	1.1	3.8	-1.5	-0.1	-1.1	0.3	-1.6	-1.1	-0.7	0.2	-0.2	-0.5	-0.2	-0.4	-0.2	-1.0	-1.3	-1.7	-1.3	-1.9
Mineral and other dietary supplements	0.7	1.0	6.9	1.1	-0.4	0.3	1.2	-0.4	-0.6	0.8	1.1	0.5	-1.2	-0.5	-0.5	-0.3	-1.4	-0.7	0.2	0.9	2.6
Breast cancer (self-reported)	0.7	0.8	2.7	0.0	-0.7	-1.1	0.0	1.6	1.0	-0.3	-0.3	-0.6	0.4	0.1	-0.7	-0.7	0.5	1.4	1.2	1.6	-0.8
Medication: Bendroflumethiazide	0.7	1.1	3.0	1.3	-0.2	-0.0	-0.8	1.7	0.5	0.9	-0.7	-0.9	-1.3	-0.3	1.2	-0.2	1.3	0.9	1.7	-1.4	1.1
Fractured/broken bones in last 5 years	0.7	0.9	2.5	0.5	1.4	-0.2	-0.4	-0.8	-1.4	0.6	0.4	0.2	-0.2	-1.6	0.9	1.4	-0.4	-1.3	-0.2	-1.2	-1.4
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	2.1	-1.3	1.2	-0.2	-0.1	-1.5	-1.2	0.5	0.2	-0.2	0.4	-1.3	1.2	1.1	0.3	-0.7	-0.8	-0.5	-1.4
Heart attack/myocardial infarction (self-reported)	0.7	0.9	6.7	-0.5	-0.3	-2.6	-0.5	0.8	1.3	-1.3	-0.2	-0.9	-0.3	1.0	-0.3	-0.4	0.3	0.2	0.4	-0.4	-1.7
Heart disease (siblings)	0.7	0.9	2.3	-0.9	-1.4	-1.4	-0.5	0.5	-0.3	-0.1	-1.1	-1.4	0.3	0.3	0.1	-1.5	1.5	1.0	0.2	-0.4	-1.1
Depression (Nagel 2018)	0.6	0.8	2.2	0.2	0.1	-1.4	-1.2	0.8	0.6	0.1	-1.3	-1.4	0.9	1.1	1.5	0.2	1.1	0.1	0.2	1.0	0.7
Schizophrenia (2018)	0.6	1.2	7.1	0.9	0.8	-1.1	-1.6	0.3	0.1	0.1	-0.4	-0.8	1.6	-0.2	0.9	0.8	0.6	-1.8	0.5	-2.7	-0.0
Ulcerative Colitis (UC)	0.6	1.2	2.9	-1.1	-0.9	-1.7	-1.6	1.5	1.0	-1.1	-1.4	-1.7	0.8	0.8	0.6	-0.9	1.3	0.3	0.3	-0.3	0.6
Reaction Time	0.6	1.1	3.0	1.6	0.6	1.5	1.5	-0.9	-0.3	1.6	1.6	1.5	-1.7	-0.4	-0.5	0.6	-0.7	-0.3	0.2	0.5	0.5
HbA1C	0.6	0.7	2.8	0.6	-0.6	-1.6	-0.5	0.6	-0.3	-0.2	0.3	-1.7	-0.9	-0.5	-0.8	-0.5	-0.5	-0.3	-0.3	0.1	1.7
Hypothyroidism (self reported)	0.6	1.4	4.5	-0.9	0.9	-0.5	0.7	-2.1	-1.5	-1.5	0.5	0.2	-0.1	-1.1	-0.2	0.9	-1.5	-2.0	-1.6	0.6	-1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.5	0.8	1.1	0.1	0.2	0.5	0.5	1.1	0.7	0.4	1.1	1.3	1.0	1.2	0.2	-0.3	0.8	1.3	1.6
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.4	0.9	0.1	-1.5	-1.0	1.2	0.9	0.3	-0.6	-0.8	0.6	1.4	0.9	0.2	0.3	0.6	0.6	0.5	0.3
Forced vital capacity (FVC)	0.6	2.3	6.6	-1.2	-2.6	0.8	-0.6	1.0	0.3	-2.1	-1.8	-2.1	0.6	-0.3	0.6	-2.5	2.1	1.1	-0.9	2.1	1.0
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	3.2	0.1	-0.5	0.9	0.8	-0.8	-0.2	0.2	0.7	1.3	-1.8	0.6	-1.1	-0.6	-1.1	0.7	-1.1	1.0	0.3
Mouth/teeth dental problems	0.6	0.9	3.7	-0.8	0.7	-0.6	-0.9	0.8	0.6	0.2	-1.0	-1.3	0.6	1.9	1.8	0.7	1.0	0.9	-0.1	0.5	0.7
Medication: Ramipril	0.6	0.7	2.6	-0.1	-0.7	-0.0	0.2	-1.0	-0.8	-1.5	-0.4	-0.8	-0.5	-0.7	-0.3	-0.7	-0.4	-1.6	-0.6	-1.2	-1.4
Neuroticism score	0.6	1.2	3.8	-0.6	-0.4	1.4	1.1	-1.5	-0.6	-0.0	0.8	1.2	-1.1	-0.1	-0.9	-0.5	-1.4	0.3	-1.9	1.9	-0.5
Father’s age at death	0.6	0.8	3.6	-1.0	-1.1	-0.5	-1.3	0.1	-0.2	-1.0	-1.0	-0.7	0.6	-0.1	-0.1	-1.2	-0.3	0.3	-0.7	-1.9	-1.0
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	4.5	-1.3	-0.4	-0.3	-0.1	-1.6	-1.9	-0.7	-0.1	-0.8	-0.3	-0.3	0.2	-0.3	-1.1	-1.0	-2.1	1.0	-0.7
Impedance of arm (left)	0.6	2.9	9.2	2.5	2.7	-1.6	-0.4	-0.7	-1.3	0.7	0.5	-0.4	-0.7	-2.2	3.0	2.9	-0.1	-2.3	1.1	-0.6	-1.9
Medication: Amlodipine	0.6	0.8	2.6	1.4	1.5	0.4	0.2	0.7	0.1	0.4	-0.4	-0.3	0.1	-0.8	1.4	1.6	0.9	-0.6	1.2	-0.8	-0.7
Medication: Omeprazole	0.6	0.7	2.5	-1.6	0.8	-0.4	-0.5	-1.0	-0.5	0.7	-0.4	-0.3	1.0	-0.9	1.1	0.7	0.5	-0.4	-0.5	-1.6	-0.6
Suffer from ‘nerves’	0.6	0.9	5.2	-1.9	-0.2	0.7	0.1	-2.0	-0.9	-0.4	-0.2	0.3	0.0	-0.6	-0.3	-0.3	-0.4	-0.1	-2.3	0.8	-1.0
Leg pain on walking	0.6	0.7	2.3	-0.9	-1.2	0.4	-0.1	0.4	0.0	-1.3	-0.8	-0.3	-1.5	0.5	-0.7	-1.2	0.0	1.0	-0.7	1.3	0.8
Medication: Aspirin	0.6	0.8	3.6	-0.2	-1.0	-0.1	-0.2	0.8	0.4	-1.9	-0.8	-1.2	-1.4	0.2	-0.9	-1.0	-0.8	-0.9	-0.4	0.2	-1.1
Ever had bowel cancer screening	0.6	0.7	3.7	-1.0	-0.9	-0.6	-0.3	-1.0	-1.9	-0.7	-0.1	-0.5	-0.2	-1.0	-0.7	-0.9	-0.2	-0.7	-0.8	-0.8	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.4	-1.3	-0.6	0.2	-0.5	0.5	0.8	-0.2	-0.7	-0.8	0.4	0.2	0.6	-0.7	1.6	1.3	-0.9	0.6	-0.2
Friendships satisfaction	0.6	0.7	6.1	-0.7	-0.9	-0.8	-0.3	0.7	1.1	0.2	-0.4	0.0	-0.2	-0.3	-0.0	-1.0	0.9	2.5	-0.3	0.9	0.7
Eye problems/disorders: Cataract	0.6	0.7	1.8	1.3	1.2	-1.1	0.1	0.4	-0.3	1.0	0.3	0.7	-0.9	-0.4	1.1	1.3	0.7	-0.2	0.6	0.5	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.1	0.5	0.4	-0.2	-0.5	0.9	1.3	-0.5	-0.9	-1.0	1.0	0.5	1.4	0.4	1.4	0.3	0.9	0.9	-0.8
Asthma (self-reported)	0.6	1.2	3.7	-0.3	1.8	-0.2	0.0	-1.3	-0.7	0.2	0.7	-0.1	0.7	-0.4	1.1	1.8	-1.0	-1.9	-1.0	-1.3	-1.8
Number of self-reported non-cancer illnesses	0.6	1.1	5.4	0.5	0.4	-0.8	-0.2	-0.4	-1.1	-1.3	-0.5	-0.7	0.3	-1.4	-0.5	0.5	-0.3	-2.3	-1.3	-0.9	-1.9
Miserableness	0.6	1.0	3.4	-0.2	1.2	-0.6	1.4	-1.8	-0.9	0.2	1.4	1.0	0.1	-0.7	-0.1	1.1	-1.3	-1.0	-0.7	0.4	-1.5
Ever taken oral contraceptive pill	0.6	0.6	3.5	-0.7	-0.5	0.6	0.1	1.2	1.8	-0.9	-0.2	-0.2	1.9	1.0	-0.4	-0.5	0.1	0.1	-0.0	0.3	0.3
Commuting to job workplace: Public transport	0.6	0.8	6.6	0.7	-0.5	-0.2	0.2	-0.0	-0.5	0.2	0.3	0.7	-2.6	0.2	0.1	-0.4	-0.2	0.9	-0.2	0.5	2.0
Medication: Paracetamol	0.6	1.0	3.7	-0.1	0.8	1.9	1.1	0.8	1.9	1.1	0.8	-0.3	0.8	0.3	1.1	0.8	0.8	0.7	1.2	0.9	-0.5
Bipolar Disorder or Schizophrenia	0.5	1.3	5.6	-0.3	0.2	-2.4	-2.0	0.3	0.6	-0.8	-0.7	-1.7	1.5	0.4	0.9	0.2	0.3	-1.4	0.2	-1.8	-0.8
Verbal and Numeric Reasoning (VNR)	0.5	1.2	6.4	-1.0	-2.5	0.1	-0.1	0.7	0.0	-0.6	-1.0	-1.4	-0.3	-0.8	0.2	-2.5	0.4	1.5	-0.5	0.1	0.9
Prostate Cancer	0.5	0.7	3.0	-0.0	0.0	1.5	0.7	-0.2	-0.0	0.9	0.8	1.6	-1.1	1.0	-0.7	0.0	-0.5	0.2	-0.2	-0.5	1.7
Bipolar Disorder (2011)	0.5	0.5	2.9	-0.8	0.1	0.4	0.5	-1.1	-0.7	-0.6	0.5	-0.4	0.0	-1.7	0.5	0.1	0.2	-0.8	-0.3	0.6	-0.8
Body Mass Index (BMI) (2010)	0.5	0.7	2.5	1.1	-0.5	0.7	0.1	1.6	1.1	0.2	-0.3	-0.5	0.6	0.1	-0.1	-0.4	0.7	0.9	1.2	1.5	1.4
Coronary Artery Disease (CAD)	0.5	0.6	2.1	-0.4	-0.3	-1.4	-0.6	0.3	1.1	-1.0	-1.1	-0.9	0.2	-0.3	0.2	-0.4	0.9	0.1	0.3	-1.1	-0.9
Crohns Disease (2012)	0.5	0.7	2.5	0.5	-1.0	1.3	0.4	0.8	0.6	-1.6	-0.6	-1.0	-0.5	-0.3	-1.1	-0.7	-0.9	-0.3	-0.2	1.6	0.3
Schizophrenia (2014)	0.5	1.0	5.2	0.6	1.3	-1.2	-1.6	-0.3	-0.5	-0.6	-0.1	-0.8	1.0	0.1	0.9	1.3	-0.2	-2.3	-0.4	-1.4	-0.7
Blood Red Count	0.5	4.6	18.6	-0.8	-0.9	-2.9	-2.8	0.1	-0.0	-1.9	-3.3	-4.3	2.2	-1.3	3.4	-0.8	1.9	-0.3	-0.3	-2.0	-2.5
Systolic Blood Pressure	0.5	2.7	13.3	0.5	2.1	0.9	-0.8	1.2	1.5	1.2	-0.1	-1.4	1.6	0.9	3.6	2.1	2.3	-0.4	2.5	-1.3	-0.8
Smoking Status	0.5	1.2	7.4	-1.9	0.6	1.1	-0.2	-0.1	0.1	0.2	-0.9	-1.1	2.7	-0.9	1.7	0.5	1.1	-0.1	-0.1	0.0	-1.4
Neuroticism	0.5	1.3	6.1	-1.7	-0.3	1.4	0.2	-1.9	-1.4	-0.6	-0.3	0.1	-0.7	-0.9	-0.1	-0.4	-0.9	-0.4	-2.5	1.1	-1.4
Hearing difficulty/problems: Yes	0.5	0.7	4.2	-0.2	0.4	-2.1	-1.2	-0.1	0.2	-0.2	-0.6	-1.3	1.1	-0.0	1.1	0.5	-0.3	-0.7	-0.4	-0.6	-0.8
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	3.0	1.7	0.5	0.2	0.5	0.6	-0.1	1.1	0.6	0.6	-1.4	0.1	-0.0	0.6	-0.0	0.0	0.9	0.1	1.1
Angina	0.5	0.6	4.2	0.2	0.4	0.5	0.3	1.1	1.0	0.5	0.4	0.2	-0.1	1.1	0.0	0.3	0.5	1.0	1.3	-0.3	-2.0
Vitamin and mineral supplements	0.5	0.7	1.9	1.1	0.5	-0.5	1.1	-0.0	0.2	0.9	1.4	0.8	-1.2	-0.4	-0.9	0.6	-0.8	-0.5	0.7	0.8	1.0
Diabetes (father)	0.5	0.6	2.3	0.7	0.2	-0.9	0.3	1.1	1.0	0.4	-0.3	0.2	-0.3	0.6	-0.2	0.2	0.9	1.5	0.7	1.4	0.6
Trunk fat percentage	0.5	1.9	5.2	0.5	2.0	0.1	1.4	-2.3	-2.0	0.9	1.2	0.0	-1.3	-1.5	1.3	2.1	-0.7	-1.9	-0.6	0.1	-1.6
Sitting height	0.5	3.4	11.6	-1.2	-1.0	1.1	1.5	-2.9	-3.4	-2.3	0.8	-0.1	-2.0	-2.5	-1.2	-1.0	-1.3	-1.7	-3.0	1.0	-1.4
Qualifications: None of the above	0.5	1.1	4.5	0.9	0.7	-0.7	-0.4	1.9	0.9	1.6	-0.2	-0.5	0.8	0.4	0.9	0.8	1.7	0.8	2.1	-0.4	0.4
Heart attack	0.5	0.7	4.0	-0.2	0.0	-2.0	-0.1	0.8	1.4	-1.0	0.1	-0.5	-0.3	1.1	-0.4	-0.1	0.2	0.2	0.7	-0.2	-1.5
Pain all over the body in last month	0.5	0.5	1.9	0.9	0.7	0.4	1.4	-0.2	0.1	-0.1	0.8	1.0	-0.8	-1.0	-0.5	0.7	-0.8	-0.5	-0.1	0.9	-0.3
Asthma	0.5	1.0	3.6	-0.3	1.5	0.0	0.1	-1.2	-0.6	-0.2	0.6	-0.2	0.5	-0.3	0.8	1.6	-0.9	-1.9	-1.0	-1.0	-1.9
Medication: Cholesterol lowering	0.5	0.7	4.1	0.1	-0.5	-1.4	-0.3	0.5	0.4	-1.1	-0.1	-0.4	-0.5	-1.5	-0.4	-0.5	-0.3	-0.2	0.4	-2.0	-1.3
Depression (self-reported)	0.5	0.5	2.2	0.7	0.5	0.1	0.3	-0.9	-1.5	0.7	0.8	0.4	-1.3	-1.4	0.2	0.6	0.1	-0.2	-0.4	0.7	0.3
Exposure to tobacco smoke at home	0.5	0.6	1.5	0.3	0.6	0.5	0.3	1.0	0.4	1.2	0.8	0.8	-1.0	0.4	-1.0	0.5	0.0	0.9	1.0	1.1	0.8
Ever highly irritable/argumentative for 2 days	0.5	0.7	1.7	0.3	1.0	0.1	0.6	-0.5	0.1	1.3	1.1	0.7	-1.1	1.1	0.8	0.9	0.0	0.9	0.2	1.1	0.7
Headache pain in last month	0.5	0.8	3.1	0.6	1.2	1.8	0.0	0.4	1.1	1.0	0.1	-0.1	1.0	0.0	1.4	1.2	0.4	0.6	0.4	1.3	-0.8
Gout (self-reported)	0.5	0.7	1.8	0.6	-1.2	-1.0	0.5	-0.3	-1.2	-0.7	-0.6	-0.7	-0.4	-1.3	-0.5	-1.2	-0.4	-0.5	-0.0	-1.0	-0.9
Eye problems/disorders: None of the above	0.5	0.6	1.9	-1.2	-0.9	0.3	0.3	-0.9	0.1	-1.4	-0.3	-0.4	0.4	0.6	-1.0	-0.9	-0.6	-0.4	-0.8	-0.6	-1.3
Angina (self-reported)	0.5	0.6	3.7	0.1	0.1	0.6	0.3	1.1	1.0	0.4	0.5	0.2	-0.4	1.1	-0.3	-0.0	0.3	1.1	1.1	-0.3	-1.9
Mean time to correctly identify matches	0.5	1.0	2.7	0.8	0.7	1.1	1.3	-1.4	-1.2	1.4	1.5	1.3	-1.6	-0.6	-0.3	0.6	-0.7	-0.5	-0.1	0.3	-0.5
Overall health rating	0.5	1.0	3.2	-0.4	-0.4	-0.9	0.8	-1.3	-0.9	-0.3	1.0	0.4	-1.4	-0.1	-1.3	-0.5	-1.8	-1.3	-1.5	1.0	-0.5
Family relationship satisfaction	0.5	0.7	3.4	-1.9	-0.0	-0.8	-1.0	0.1	0.4	-0.5	-1.0	-0.8	0.3	-1.0	0.9	-0.2	0.8	0.0	-0.9	-0.7	-1.1
Commuting to job workplace: Car/motor vehicle	0.5	0.5	2.1	-0.5	-0.8	-0.4	-0.3	1.0	0.6	-0.2	-0.4	-0.5	1.0	0.9	-1.5	-0.9	0.4	0.9	0.5	0.6	-0.8
Illness, injury, bereavement, stress in last 2 years	0.5	0.7	1.9	0.9	-0.6	-0.1	0.0	1.4	0.4	0.5	-0.1	0.3	0.0	1.1	-0.4	-0.6	1.1	1.4	1.3	0.2	1.3
Mood swings	0.5	1.0	3.1	-0.9	0.8	1.1	1.4	-1.8	-0.5	-0.1	1.1	0.9	-0.3	-0.9	-0.0	0.8	-1.6	-1.0	-1.3	0.5	-1.0
Medication: Aspirin	0.5	0.6	2.6	-0.1	-0.7	-0.1	-0.4	1.1	0.5	-1.6	-0.9	-1.2	-1.6	0.1	-0.2	-0.6	-0.3	-0.6	-0.0	0.4	-1.0
Illnesses of father: None of the above (group 1)	0.5	0.6	2.4	-0.0	-0.7	-1.6	0.1	-0.5	-1.1	-0.8	0.0	-0.0	-1.0	-1.2	-0.1	-0.6	-1.2	-0.5	-0.8	-0.5	0.2
Smoking status: Current	0.5	0.7	2.9	0.1	0.7	1.7	1.2	0.1	0.3	1.6	1.4	0.7	0.6	-0.9	-0.3	0.5	-0.5	0.5	0.5	0.6	0.8
Intelligence (Savage-Jansen 2018)	0.4	1.1	5.1	-0.0	-1.0	0.3	-0.3	1.5	1.0	0.7	-0.4	-0.3	0.4	0.9	0.4	-1.1	1.6	2.3	1.3	0.1	1.6
Breast Cancer	0.4	0.9	3.0	-0.1	-0.2	-0.1	-1.5	-0.9	-1.7	-0.3	-0.9	-0.8	-1.2	-1.1	1.6	-0.2	-0.3	-0.5	-1.1	-1.1	-0.9
Ovarian Cancer	0.4	0.5	2.9	0.1	-0.1	-0.4	0.2	0.5	0.4	1.0	0.4	0.9	0.7	1.7	-0.7	-0.1	0.5	1.1	0.5	0.5	1.2
Triglycerides	0.4	0.7	2.8	0.6	-0.7	-1.0	-0.7	0.9	-0.5	-0.6	-1.4	-1.4	-0.1	-0.7	0.6	-0.5	1.7	0.2	-0.5	0.9	0.1
Height	0.4	7.0	15.9	-1.6	-1.4	4.0	3.7	-3.3	-2.8	-2.9	1.7	2.1	-1.5	-1.6	-4.0	-1.4	-2.4	-0.9	-3.6	3.4	-1.8
Waist Hip Ratio (WHR)	0.4	1.7	4.2	-0.9	2.0	0.3	0.6	-2.0	-1.9	1.2	1.7	1.2	-0.1	-0.6	1.6	1.9	-0.5	-1.8	0.1	-1.2	-0.9
Cardiovascular Disease	0.4	1.4	4.7	1.5	1.4	0.4	-0.3	0.9	0.2	0.4	-0.2	-1.1	0.3	-2.2	1.7	1.5	0.9	-1.5	1.4	-1.6	-0.4
Number of treatments/medications taken	0.4	0.7	5.9	0.1	1.1	-0.1	-0.2	0.6	0.4	-0.6	-0.7	-0.8	0.4	0.0	0.7	1.1	1.0	-0.8	0.2	-0.9	-2.4
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.4	-1.1	-0.7	-0.8	-0.8	0.4	0.7	-0.7	-1.0	-1.2	0.2	0.1	0.3	-0.6	0.4	0.5	-0.7	1.0	0.4
Systolic blood pressure, automated reading	0.4	1.3	8.3	-0.3	1.2	0.7	-1.0	0.1	-0.2	0.2	-1.0	-1.6	0.5	0.1	2.9	1.2	1.6	-0.4	0.6	-0.6	-1.5
Impedance of leg (right)	0.4	1.9	6.7	0.3	1.9	-0.7	-0.2	1.3	2.6	0.5	0.5	-0.9	1.0	-0.6	2.4	1.9	0.9	0.3	2.3	1.1	-1.1
Current tobacco smoking	0.4	0.6	2.8	-0.0	0.7	1.4	1.0	0.1	0.3	1.7	1.2	0.5	0.6	-0.8	0.1	0.6	-0.4	0.4	0.4	0.7	0.9
Age when periods started (menarche)	0.4	1.0	3.3	-1.4	-1.7	1.7	-0.8	0.7	0.2	-1.3	-1.0	-0.8	0.1	0.4	-0.5	-1.8	0.3	1.0	-0.5	-0.8	-0.4
High blood pressure	0.4	1.2	3.4	0.0	0.5	-0.4	-1.0	1.6	0.5	-0.9	-1.8	-1.8	0.4	-1.4	1.7	0.6	1.8	-0.2	0.7	-0.5	-1.1
Medication: Levothyroxine sodium	0.4	0.7	1.6	-0.3	1.0	-1.1	-1.1	-0.6	-0.3	-1.3	-1.0	-1.1	0.7	-0.1	0.9	1.0	0.2	-1.2	-0.7	0.3	-0.8
Trunk fat mass	0.4	1.8	6.2	0.1	1.6	0.7	1.6	-2.5	-2.2	0.6	1.2	0.2	-1.4	-1.5	0.7	1.6	-0.8	-1.6	-1.1	0.4	-1.2
Arm fat percentage (right)	0.4	1.5	5.0	1.4	2.1	-0.5	0.4	-1.3	-1.6	1.1	0.3	-0.4	-1.0	-0.9	2.0	2.2	0.1	-1.5	-0.0	-0.1	-1.1
Worrier / anxious feelings	0.4	0.7	2.7	1.1	0.1	0.9	1.0	-0.9	-0.1	0.7	1.1	1.1	-0.9	-0.1	-0.8	0.1	-1.6	0.2	-0.4	1.2	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	2.2	0.7	0.3	1.5	0.3	0.0	0.6	1.3	0.9	0.9	-0.2	1.5	0.1	0.3	-0.7	1.1	0.1	1.1	0.4
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	1.8	-0.7	-0.4	1.0	0.3	-0.9	-0.8	0.6	0.4	1.0	0.0	1.1	-0.6	-0.4	-0.6	0.3	-1.0	1.4	1.3
Glaucoma (self-reported)	0.4	0.5	2.2	0.5	0.6	-0.9	-0.2	1.0	0.9	0.6	0.1	-0.1	1.1	0.2	0.5	0.5	1.5	0.4	1.1	-0.1	-0.1
Body fat percentage	0.4	1.6	5.1	0.6	2.2	-0.0	1.2	-1.8	-1.4	1.1	1.1	0.0	-1.0	-1.4	1.4	2.3	-0.4	-1.5	-0.2	0.1	-1.6
Arm fat-free mass (right)	0.4	2.2	6.4	-2.4	-1.5	1.9	1.6	-1.7	-1.1	-1.3	0.5	0.4	-0.8	-0.0	-2.4	-1.7	-0.9	0.4	-2.5	1.4	0.8
Comparative body size at age 10	0.4	1.1	5.9	0.7	-0.1	2.4	0.1	-0.4	-1.5	1.1	0.5	2.0	-1.0	0.9	-1.2	-0.1	-0.5	-0.6	-0.2	-0.4	1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	2.6	0.3	-0.3	0.8	-0.4	-0.7	0.1	-1.0	-0.6	-0.2	-0.2	0.9	-0.4	-0.3	-1.6	-1.0	-0.5	-0.6	-0.4
Medication: Blood pressure	0.4	0.7	2.1	1.4	0.9	0.3	0.2	1.3	1.4	0.0	-0.1	-0.5	-0.7	-0.6	0.6	0.9	0.7	0.2	1.4	-0.7	-0.8
Arm predicted mass (right)	0.4	2.2	6.1	-2.5	-1.4	2.1	1.6	-1.8	-1.1	-1.0	0.6	0.6	-0.7	0.0	-2.4	-1.6	-0.9	0.7	-2.4	1.1	0.8
Age at last live birth	0.4	0.6	1.7	-0.4	0.1	-0.0	-0.5	0.5	0.9	-1.3	-1.2	-0.9	0.6	-0.4	1.0	0.1	1.3	-0.8	-0.2	-1.1	-0.9
Illnesses of father: Heart disease	0.4	0.6	2.1	-0.0	-0.8	1.1	0.1	0.7	1.1	0.3	0.3	-0.2	-0.4	0.9	-0.9	-1.0	0.3	1.4	0.8	0.9	-0.8
Arm fat percentage (left)	0.4	1.5	4.3	0.9	1.9	-0.5	0.4	-1.7	-2.1	0.8	0.3	-0.4	-1.1	-1.1	1.6	1.9	-0.3	-1.7	-0.5	-0.4	-1.2
Qualifications: nursing, teaching	0.4	0.7	3.5	0.8	-0.3	-0.7	-0.1	1.0	1.0	-0.1	0.3	0.3	0.1	1.9	-1.3	-0.4	0.0	1.3	0.7	1.0	0.2
Mother’s age at death	0.4	0.6	2.4	0.6	0.4	-0.7	-1.3	1.0	0.3	-0.0	-0.6	-0.2	-0.6	-0.6	0.9	0.4	1.0	-0.0	0.8	-1.5	0.3
High cholesterol (Self-reported)	0.4	0.8	3.0	1.6	0.8	0.3	0.3	1.2	1.1	0.1	0.5	0.5	0.0	-0.1	-0.5	0.8	-0.6	-0.6	1.7	-1.5	-0.5
Myopia	0.4	0.6	1.9	-0.5	1.3	-0.0	0.6	-1.4	-0.7	-0.2	0.7	1.2	-0.1	-0.0	0.6	1.2	-0.3	-1.1	-0.7	-0.1	-1.1
Vascular/heart problems diagnosed by doctor	0.4	1.1	3.1	-0.4	-0.7	0.1	0.6	-1.7	-0.7	0.7	1.5	1.5	-0.5	1.3	-1.4	-0.8	-1.7	0.2	-1.0	0.6	1.5
Alcohol drinker status: Previous	0.4	0.5	3.0	-0.2	0.9	0.3	0.3	-0.5	0.5	1.2	0.5	0.4	0.8	-0.5	0.4	0.8	-0.8	0.1	0.1	-1.7	-0.5
Neuroticism (Nagel 2018)	0.3	0.7	2.1	-1.5	0.1	1.0	-0.2	-1.4	-0.8	-0.2	-0.3	-0.3	-0.6	-0.7	0.5	0.0	-0.8	-0.7	-1.4	0.5	-1.1
Schizophrenia vs Biploar Disorder	0.3	0.4	2.1	0.9	0.1	1.4	0.0	-0.2	-0.4	0.3	0.3	1.0	-0.1	0.7	-0.7	0.1	-0.4	-0.7	-0.3	-1.3	-0.1
Worry (Nagel 2018)	0.3	0.6	2.3	-0.5	-0.3	0.9	-0.6	-1.0	-1.0	-0.3	-0.9	-0.5	-1.4	-1.2	0.4	-0.3	-0.7	-0.4	-1.5	0.5	0.1
Crohns Disease (2017)	0.3	0.6	2.5	0.7	-0.9	1.4	0.7	0.5	-0.6	-1.2	-0.4	-0.7	-0.5	-0.8	-0.7	-0.7	0.1	-0.3	-0.2	1.6	0.2
Irritable Bowel Disease (IBD)	0.3	0.7	2.6	-0.5	-1.3	-0.4	-0.6	1.2	0.2	-1.6	-1.2	-1.6	-0.2	-0.1	-0.3	-1.1	0.6	0.1	-0.0	0.5	0.3
Age at First Birth	0.3	0.4	1.2	0.9	0.1	-0.2	1.1	0.4	-0.3	0.8	1.1	0.4	0.5	0.8	-0.6	0.1	0.2	-0.2	1.0	0.6	0.9
HDL Cholesterol	0.3	0.6	2.7	-0.3	1.1	1.1	0.7	-0.1	0.3	1.0	1.6	1.1	-0.4	0.9	-0.2	0.9	-0.4	0.1	0.5	-0.1	-0.3
Allergy or Eczema	0.3	0.8	2.3	-1.5	-0.7	0.8	-0.1	-0.5	-1.1	-1.0	-0.6	-1.1	-0.7	-1.5	0.1	-0.6	0.3	-0.1	-1.3	1.3	-0.7
Chronotype (morning person)	0.3	0.6	2.4	1.3	0.5	1.2	1.5	0.6	0.5	0.5	0.7	1.1	0.4	-0.1	-0.1	0.4	1.0	0.1	0.7	1.1	0.0
Sensitivity / hurt feelings	0.3	0.5	2.2	0.5	0.7	1.5	0.6	0.1	0.7	0.5	0.6	0.9	0.6	1.0	0.2	0.6	-0.2	0.7	0.4	0.4	-1.0
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	3.1	-0.4	-0.5	-0.6	0.7	-0.4	-0.2	-0.7	-0.3	-0.5	0.5	-0.4	-0.8	-0.6	-0.2	-0.2	-0.8	0.5	-1.8
Medication: Metformin	0.3	0.4	2.2	0.8	-0.0	0.1	0.5	0.4	-0.4	0.5	-0.4	-1.0	-0.6	-1.5	0.2	0.1	0.3	0.1	1.1	-0.3	0.3
Leg fat-free mass (left)	0.3	1.6	5.1	-0.4	0.3	1.9	1.5	-2.2	-2.3	-0.1	1.0	1.2	-1.0	-0.1	-1.1	0.2	-1.0	-0.6	-2.1	0.8	0.8
Townsend deprivation index at recruitment	0.3	0.4	2.3	0.0	0.5	0.9	0.4	0.4	0.1	0.9	0.3	0.0	0.3	0.1	0.5	0.5	0.2	0.2	0.6	0.8	1.5
Serious illness, injury or assault to yourself	0.3	0.4	2.2	0.1	0.2	0.1	0.4	-0.2	0.1	-0.7	0.5	-0.0	-0.2	-0.5	-0.1	0.3	-1.1	-1.1	-0.3	-0.9	-1.5
Leg predicted mass (left)	0.3	1.4	5.0	-0.5	0.2	1.8	1.3	-2.1	-2.2	-0.2	0.9	1.2	-0.9	-0.1	-1.0	0.2	-0.9	-0.6	-2.1	0.7	0.8
Waist circumference	0.3	1.0	3.5	-0.5	1.4	0.5	1.0	-1.9	-1.7	0.8	0.9	0.1	-0.5	-1.0	0.8	1.4	-0.4	-1.4	-0.5	0.1	-0.3
Had other major operations	0.3	0.4	1.9	0.8	0.4	0.2	0.7	-0.4	-1.0	0.3	0.8	1.0	-1.4	-0.3	-0.3	0.4	0.3	0.1	-0.0	0.8	-0.2
Medication: Simvastatin	0.3	0.5	2.1	0.3	-0.2	-0.8	-0.8	1.0	0.5	-0.7	-0.8	-1.1	0.2	-1.4	0.4	-0.1	0.0	-0.1	1.0	-0.8	-0.0
Weight	0.3	1.3	4.5	-0.7	0.5	1.6	1.8	-2.1	-1.8	-0.1	1.1	0.6	-1.2	-0.7	-0.7	0.5	-0.8	-0.7	-1.6	1.4	-0.2
Trunk fat-free mass	0.3	1.9	5.2	-1.6	-1.5	2.3	1.2	-1.3	-1.3	-1.1	0.3	0.5	-1.1	0.1	-2.0	-1.6	-0.3	0.8	-2.2	1.8	1.4
Hip circumference	0.3	1.1	3.1	-0.4	0.7	1.3	1.7	-1.8	-1.6	0.3	1.2	0.2	-1.1	-1.5	-0.3	0.7	-1.1	-1.0	-0.8	1.1	-0.0
Alcohol intake versus 10 years previously	0.3	0.5	2.9	-0.7	0.3	1.5	0.4	0.1	-0.1	-1.3	0.1	-0.2	1.1	-0.4	-0.3	0.3	-0.0	-1.7	0.0	0.0	-0.3
Number of live births	0.3	0.4	1.7	0.0	0.4	0.3	-1.1	0.6	0.2	0.8	-0.4	-0.3	-0.2	1.0	0.8	0.4	0.1	-0.0	0.3	-0.9	1.3
Noisy workplace	0.3	0.4	1.6	0.7	-0.4	0.7	1.0	0.2	0.8	-0.7	0.5	-0.2	0.3	1.3	-1.2	-0.3	0.2	-0.6	0.2	0.4	0.3
Qualifications: A levels/AS levels or equivalent	0.3	0.7	4.0	0.5	-0.6	0.0	0.6	0.5	-0.0	0.2	0.4	0.2	-1.6	0.9	-0.9	-0.5	0.1	0.9	-0.5	2.0	1.1
Trunk predicted mass	0.3	1.8	4.8	-1.6	-1.5	2.2	1.1	-1.2	-1.3	-1.2	0.2	0.4	-1.1	0.0	-1.9	-1.6	-0.3	0.8	-2.2	1.6	1.4
Standing height	0.3	2.9	7.6	-0.9	-0.9	2.5	2.3	-2.2	-2.3	-1.7	1.3	0.7	-1.7	-1.6	-1.5	-0.9	-1.1	-0.3	-2.3	2.8	0.1
Medication: Ventolin 100micrograms inhaler	0.3	0.3	1.6	0.0	0.2	-0.4	-0.2	-0.8	-0.7	-0.1	-0.0	-1.3	-1.0	-0.0	0.1	0.3	-0.9	-0.9	-0.4	-0.2	0.2
Leg fat percentage (right)	0.3	1.1	4.8	-0.0	2.2	0.4	0.5	-0.5	0.4	1.1	0.4	-0.5	0.3	-0.3	2.0	2.1	0.8	-0.3	0.6	0.7	-1.3
Number of full brothers	0.3	0.4	1.4	-0.3	-0.2	-0.1	1.0	0.4	1.2	0.9	0.4	0.2	0.2	1.1	-0.1	-0.3	0.3	1.1	0.3	0.5	0.2
Wheeze or whistling in the chest in last year	0.3	0.6	2.3	-0.1	0.0	-0.8	-0.2	-1.1	-1.5	-0.5	0.0	-1.0	-0.6	-0.2	0.1	0.2	-1.1	-1.1	-1.3	-0.1	-0.5
Qualifications: College or University degree	0.3	1.0	3.0	-0.8	-1.7	-0.5	-1.1	-0.6	-0.7	-1.1	-0.4	-0.7	-1.2	0.6	-0.2	-1.7	-0.9	-0.3	-1.5	-1.2	0.8
Medication: Allopurinol	0.3	0.4	3.1	1.0	-0.1	-1.8	-0.1	0.5	-0.5	0.2	-0.9	-0.4	-0.1	0.2	0.1	0.0	0.5	0.1	0.5	-0.8	-0.4
Whole body fat mass	0.3	1.3	3.8	0.3	1.7	0.9	1.6	-2.0	-1.6	0.8	1.2	0.4	-1.2	-1.0	0.6	1.6	-0.6	-1.2	-0.7	0.5	-1.0
Comparative height size at age 10	0.3	1.5	8.1	-0.1	0.1	-0.4	2.1	-1.5	-1.7	-0.6	1.4	0.2	-1.1	-2.8	-1.0	0.1	-1.1	-1.0	-0.9	0.7	-1.1
Hypertension (Self-reported)	0.3	0.9	2.4	0.5	1.0	0.4	-0.5	1.1	0.2	-0.5	-1.3	-1.2	0.3	-1.5	1.5	1.0	1.3	-0.8	0.6	-0.5	-1.1
Illnesses of siblings: Diabetes	0.3	0.4	1.8	0.4	0.2	-0.8	0.8	-0.4	-0.7	-0.1	0.2	0.2	0.6	-0.7	-0.4	0.1	-0.0	-1.1	0.2	-1.3	-1.0
Whole body fat-free mass	0.3	1.7	5.2	-1.3	-1.0	2.0	1.3	-1.7	-1.6	-0.8	0.6	0.8	-1.1	0.1	-1.8	-1.0	-0.7	0.2	-2.3	1.3	1.2
Leg fat-free mass (right)	0.3	1.8	6.1	-0.3	-0.4	1.7	1.5	-2.1	-2.5	-0.4	0.9	1.1	-1.4	-0.0	-1.5	-0.4	-1.1	-0.6	-2.2	0.8	1.0
Loneliness, isolation	0.3	0.4	2.2	-0.9	-0.9	-0.3	-0.6	-0.7	-0.7	-0.3	-0.1	-0.2	-0.3	-0.0	-0.7	-0.9	-1.0	-0.2	-1.5	0.1	-0.0
Commuting to job workplace: Walk	0.3	0.3	1.7	0.6	-0.0	1.3	-0.1	0.2	0.1	0.2	-0.2	0.5	-1.0	-0.6	0.7	0.0	0.0	0.3	0.3	-0.9	0.9
Mouth/teeth dental problems: Mouth ulcers	0.3	0.6	1.9	1.1	1.2	0.7	-0.3	-0.2	0.0	0.5	0.2	0.7	-0.2	-0.5	0.4	1.3	0.3	-1.4	0.4	-0.9	1.0
Osteoporosis (self-reported)	0.3	0.4	1.9	0.4	0.1	-0.6	0.6	-0.1	0.1	-0.7	0.2	-0.3	1.3	-0.5	-0.1	0.0	-0.2	-1.0	-0.0	-0.4	-1.4
Whole body water mass	0.3	1.8	5.3	-1.2	-0.9	2.1	1.6	-1.8	-1.7	-0.8	0.8	1.0	-1.1	-0.1	-1.9	-0.9	-0.9	0.1	-2.3	1.4	1.1
Leg predicted mass (right)	0.3	1.8	6.0	-0.4	-0.3	1.8	1.6	-2.2	-2.5	-0.3	1.0	1.2	-1.4	-0.1	-1.5	-0.3	-1.1	-0.7	-2.2	0.7	1.0
Arm fat mass (left)	0.3	1.1	4.0	0.3	1.2	0.6	1.3	-2.0	-2.0	0.4	0.8	0.2	-1.1	-0.9	0.3	1.3	-0.8	-1.4	-1.0	0.3	-0.8
Hearing aid user	0.3	0.3	1.7	0.1	0.6	-0.5	0.2	0.7	1.2	0.1	0.3	0.7	-0.0	0.3	-0.2	0.5	0.2	0.7	0.4	0.2	-1.3
Supplements: Fish oil (including cod liver oil)	0.3	0.4	2.0	-0.5	0.5	0.9	0.0	-0.1	0.3	0.2	0.1	0.6	0.6	0.6	-0.4	0.4	0.4	0.6	0.2	-1.2	-1.4
Basal metabolic rate	0.3	1.6	4.8	-1.1	-0.4	2.0	1.6	-1.9	-1.8	-0.7	0.8	0.9	-1.1	-0.1	-1.5	-0.5	-0.8	-0.2	-2.2	1.3	0.8
Arm fat-free mass (left)	0.3	1.7	4.3	-2.0	-1.2	2.0	1.4	-1.4	-0.8	-1.1	0.6	0.5	-0.7	0.2	-2.0	-1.3	-0.7	0.5	-2.1	1.4	0.6
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.1	0.3	-0.1	-0.6	-1.0	0.9	0.2	0.2	-0.7	-0.5	0.3	0.6	0.7	-0.2	-0.1	0.4	0.1	-0.9	0.3
Diastolic blood pressure, automated reading	0.3	0.8	4.5	-0.2	1.5	1.4	0.5	-0.3	0.6	0.8	0.2	-0.1	0.8	-0.3	2.1	1.4	1.2	-0.2	0.6	-0.2	-0.5
Ever depressed for a whole week	0.3	0.4	1.3	-1.1	-0.3	-0.5	-0.9	-0.3	-0.7	0.5	-0.7	0.3	-0.4	-0.3	0.1	-0.4	0.7	0.7	-0.8	-0.7	-0.5
Unable to work because of sickness or disability	0.3	0.4	1.6	0.4	0.6	0.7	0.6	-0.5	-1.3	0.1	0.3	0.7	-0.1	-0.7	0.2	0.6	-0.0	-0.8	-0.9	1.2	-0.6
Cholesterol lowering medication	0.3	0.4	1.2	0.2	-0.1	0.8	-0.5	0.3	-0.5	-0.1	-0.9	-1.0	0.0	-0.8	0.6	-0.1	-0.1	-0.8	0.9	-1.1	-0.6
Supplements: Calcium	0.3	0.3	1.6	-0.5	0.4	0.7	0.3	-0.6	0.2	-0.0	0.3	1.1	-0.3	-0.4	-0.2	0.2	-0.0	1.2	-0.4	-0.1	-1.0
Impedance of whole body	0.3	1.6	4.8	1.6	2.0	-1.4	-0.1	0.1	0.3	0.4	0.8	-0.6	-0.7	-1.7	2.2	2.2	-0.2	-1.3	1.5	0.5	-1.8
Arm predicted mass (left)	0.3	1.8	4.8	-1.8	-1.1	2.2	1.7	-1.4	-0.8	-1.1	0.6	0.6	-0.9	0.1	-2.1	-1.2	-0.8	0.5	-2.0	1.7	0.8
Alzheimer’s Disease (in father)	0.2	0.2	1.0	-1.0	-0.3	0.4	-0.2	-0.1	0.2	0.3	-0.2	0.2	0.2	0.4	0.4	-0.5	0.3	0.2	-0.9	-0.2	0.3
LDL Cholesterol	0.2	0.3	1.1	0.3	-1.0	-0.1	0.5	-0.3	-0.6	-0.5	0.3	-0.9	-1.1	-0.5	-0.2	-1.0	-0.2	-0.4	-0.2	0.7	-0.1
Blood Eosinophil Count	0.2	1.6	7.4	0.1	0.4	-0.4	-1.4	1.4	1.1	0.4	-1.8	-1.5	1.6	-0.1	1.7	0.3	2.7	1.6	0.3	0.7	-1.4
BMI	0.2	1.3	3.5	0.1	1.8	0.4	1.1	-1.9	-1.7	1.2	1.1	0.9	-0.7	-0.8	0.5	1.8	-0.8	-1.5	-0.5	-0.7	-0.7
Diabetes (mother)	0.2	0.2	2.6	0.1	-0.1	-0.0	-0.7	0.3	0.4	0.5	0.0	0.2	0.1	0.6	-0.2	-0.3	0.1	0.1	0.1	-1.6	-0.2
Maternal smoking around birth	0.2	0.3	1.0	-0.7	-0.6	0.6	0.7	-0.0	-0.9	0.2	0.1	-0.4	0.3	-0.8	-0.2	-0.6	-0.3	0.5	-0.4	0.3	-1.0
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.6	-1.1	-0.3	0.9	0.7	-0.5	-0.5	-0.5	0.3	-0.3	-0.6	-1.0	-0.5	-0.3	-0.3	-0.3	-0.9	1.2	0.0
Multivitamins +/- minerals	0.2	0.3	1.8	-0.3	0.0	0.8	0.1	-0.0	0.5	0.1	-0.1	0.4	1.3	0.4	-0.1	-0.1	0.3	0.9	-0.5	0.3	-0.7
Impedance of leg (left)	0.2	1.2	4.5	0.4	1.0	-1.1	0.0	1.1	2.1	-0.0	0.5	-1.1	0.3	-0.8	1.7	1.0	0.5	-0.0	2.0	1.1	-1.1
Nervous feelings	0.2	0.4	2.6	-0.5	-0.1	1.6	-0.1	-0.5	-0.1	0.4	0.3	0.2	-0.9	0.3	-0.2	-0.1	-0.5	0.1	-0.8	1.3	0.7
Financial difficulties in last 2 years	0.2	0.3	1.1	0.3	0.5	0.8	0.2	-0.9	0.1	-0.2	-0.0	0.2	0.0	-0.5	-0.1	0.5	-0.9	-0.4	-0.6	1.0	-1.1
Allergy	0.2	0.5	2.0	1.1	0.4	-0.6	-0.5	0.6	0.6	0.7	-0.3	0.1	0.7	0.6	0.8	0.4	0.9	0.5	1.4	-0.7	0.8
Fluid intelligence score	0.2	0.5	1.4	-1.1	-1.1	0.6	-0.1	0.2	0.1	-0.2	-0.5	-0.9	0.7	-0.7	0.9	-1.2	-0.4	0.1	-0.2	-0.6	0.6
Falls in the last year	0.2	0.2	1.3	0.1	0.1	-1.1	0.1	-0.0	-0.5	-0.4	-0.4	-0.6	0.3	-0.3	0.1	0.1	0.7	-0.2	0.0	0.9	-0.2
Prospective memory result	0.2	0.3	1.1	-0.4	-1.0	0.1	0.0	0.3	0.5	0.0	-0.1	-0.5	-0.3	-0.1	-0.4	-1.1	0.4	0.9	0.4	0.1	1.0
Arm fat mass (right)	0.2	0.9	2.9	0.3	1.4	0.6	1.2	-1.7	-1.6	0.5	0.7	0.1	-0.9	-0.7	0.6	1.4	-0.5	-1.2	-0.7	0.4	-0.8
Hair/balding pattern: Pattern 4	0.2	0.5	2.1	-0.2	0.4	-0.1	-1.4	0.0	0.4	-1.0	-0.4	0.4	-0.9	1.1	-0.1	0.3	-0.1	-0.4	-0.7	-1.0	-1.4
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	1.4	-0.8	0.5	-1.0	-0.3	-1.2	-0.7	-0.9	-0.4	-0.5	0.7	-0.2	0.7	0.5	0.1	-0.9	-0.9	0.0	-0.5
Birth weight	0.2	0.5	2.2	1.1	1.0	-0.1	-0.0	-0.5	-0.4	0.9	0.3	0.3	0.2	0.3	0.4	1.1	-1.5	-1.1	-0.0	-0.3	0.7
Age at first live birth	0.2	0.4	2.5	-0.6	0.8	-0.1	0.6	-0.1	0.5	-0.4	0.5	0.7	0.6	-0.4	0.3	0.6	0.2	-0.8	-0.0	-0.8	-1.6
Shortness of breath walking on level ground	0.2	0.3	0.8	0.6	-0.0	0.4	-0.7	-0.3	-0.8	-0.3	-0.8	-0.6	-0.9	-0.1	0.5	0.1	-0.2	-0.6	-0.9	-0.3	0.2
Leg fat mass (right)	0.2	0.8	2.9	-0.1	1.7	0.9	1.1	-1.3	-0.6	0.6	0.9	0.1	-0.3	-0.4	0.9	1.7	-0.1	-0.8	-0.3	0.6	-0.7
Alcohol intake frequency.	0.2	0.4	1.1	0.4	1.0	0.7	0.7	-0.1	0.4	0.6	1.0	0.5	-0.2	-0.7	-0.6	1.1	-0.5	-0.5	0.5	0.5	0.4
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.4	-0.1	0.1	-0.6	-0.7	0.3	0.4	-0.2	-1.2	-0.9	0.1	0.2	0.9	0.2	0.2	0.5	-0.2	0.3	0.7
Tinnitus: Yes, now most or all of the time	0.2	0.3	1.3	-1.1	-0.5	0.2	-0.5	0.4	0.4	-0.0	-0.5	-0.4	-0.5	0.4	-0.4	-0.5	-0.0	0.4	-0.4	-0.6	0.7
Eye problems/disorders: Glaucoma	0.2	0.3	0.8	0.7	0.2	0.0	-0.3	0.5	0.1	0.4	-0.1	-0.2	0.6	-0.8	0.7	0.2	0.9	-0.0	0.8	-0.2	0.7
Medication: Blood pressure	0.2	0.4	1.0	0.6	0.2	0.9	-0.1	0.7	-0.5	0.1	-0.6	-0.8	-0.8	-1.0	0.6	0.3	0.8	-0.3	0.9	0.3	-0.7
Leg fat percentage (left)	0.2	0.6	2.3	-0.1	1.4	-0.0	0.5	-0.6	-0.1	0.7	0.2	-0.7	-0.0	-0.6	1.5	1.4	0.6	-0.5	0.3	0.6	-1.3
Irritability	0.2	0.4	2.2	-0.4	0.3	-0.2	0.5	0.3	1.5	-0.8	-0.0	-0.6	1.1	0.5	0.5	0.3	-0.1	-0.6	0.4	0.6	-0.6
Commuting to job workplace: Cycle	0.2	0.2	1.0	0.3	0.3	-1.0	0.2	0.2	0.4	0.1	0.3	0.6	-0.3	0.6	-0.1	0.2	-0.2	0.9	0.4	0.4	0.4
Leg fat mass (left)	0.2	0.6	2.0	-0.2	1.4	0.6	1.0	-1.4	-0.9	0.5	0.6	-0.1	-0.5	-0.5	0.7	1.3	-0.2	-0.9	-0.5	0.6	-0.7
Hair Pigment	0.1	3.3	10.9	2.8	1.6	-2.8	0.0	2.2	1.8	0.7	0.1	0.2	3.3	2.2	0.7	1.7	1.5	0.9	2.7	2.0	0.2
Tanning	0.1	1.5	5.7	-1.0	-0.6	0.3	-1.8	1.0	0.0	-1.1	-2.4	-2.1	0.3	-0.9	1.2	-0.6	2.0	-0.2	-0.4	-0.9	-1.1
Body mass index (BMI)	0.1	0.4	1.6	-0.5	0.8	0.4	0.8	-1.3	-0.9	0.4	0.3	0.1	-0.6	-0.1	-0.0	0.8	-0.4	-0.7	-0.8	0.1	-0.5
Pulse rate	0.1	0.2	1.1	-0.5	-0.3	-0.4	-0.3	-0.4	0.2	0.0	-0.3	-0.2	1.1	0.6	0.2	-0.3	0.1	-0.2	-0.6	-0.7	-0.5
Blood clot in the leg (DVT)	0.1	0.2	0.6	-0.1	0.2	0.2	-0.0	-0.3	-0.1	-0.6	0.1	0.2	-0.4	-0.4	-0.3	0.3	-0.6	-0.7	-0.8	-0.0	-0.3
Pulse rate, automated reading	0.1	0.4	1.8	-0.5	0.8	-0.0	0.4	-0.6	0.2	0.6	0.5	0.6	0.3	0.2	0.8	0.6	-0.2	-0.2	0.1	-1.4	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.4	0.1	0.1	0.5	0.2	-0.1	0.2	-0.4	0.2	0.4	-0.6	0.0	-0.6	0.1	-0.5	-0.4	-0.6	0.4	0.3

Hub : Genes

ITGA2

Models

Trait associations