[Hub]/) : Traits : Lung FVC : ← →

chr5:121,153,924-123,058,338

Best TWAS P=5.73e-12 · Best GWAS P=2.07e-13 conditioned to 0.000661

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CTB-36H16.2 0.09 0.06 enet 30 0.07 3.5e-06 -7.0 6.6 5.2e-11 -0.76 0.04 0.96 FALSE
2 GTEx Artery Aorta CTB-36H16.2 0.12 0.15 lasso 3 0.12 2.6e-07 -6.9 6.9 5.7e-12 -0.68 0.04 0.96 TRUE
3 GTEx Artery Coronary RN7SL689P 0.17 0.16 lasso 13 0.14 1.8e-05 5.5 -5.5 4.3e-08 0.35 0.87 0.01 FALSE
4 GTEx Artery Tibial CTB-36H16.2 0.15 0.12 lasso 6 0.09 8.1e-08 -6.6 6.7 1.8e-11 -0.73 0.30 0.70 FALSE
5 GTEx Breast Mammary Tissue PPIC 0.06 0.06 lasso 2 0.06 8.4e-04 5.1 -5.4 6.5e-08 0.38 0.42 0.14 FALSE
6 GTEx Cells Transformed fibroblasts PPIC 0.11 0.08 enet 13 0.10 1.4e-07 5.1 -5.2 2.1e-07 0.37 1.00 0.00 FALSE
7 GTEx Esophagus Mucosa PPIC 0.15 0.06 enet 35 0.07 2.3e-05 5.1 -5.2 2.0e-07 0.35 0.87 0.01 FALSE
8 GTEx Esophagus Muscularis CTB-36H16.2 0.08 0.08 lasso 2 0.04 1.5e-03 -6.5 6.5 6.9e-11 -0.72 0.06 0.86 FALSE
9 GTEx Nerve Tibial SNX24 0.14 0.17 enet 20 0.17 3.6e-12 5.0 -5.5 4.0e-08 0.46 1.00 0.00 FALSE
10 GTEx Ovary PPIC 0.28 0.07 lasso 7 0.04 3.6e-02 5.5 -5.9 4.2e-09 0.35 0.12 0.12 FALSE
11 GTEx Pancreas PPIC 0.25 0.12 lasso 13 0.10 4.0e-05 5.5 -5.4 6.0e-08 0.28 0.98 0.01 FALSE
12 NTR Blood PPIC 0.01 0.00 blup 443 0.00 8.7e-03 5.6 6.3 2.4e-10 -0.55 0.17 0.38 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma PPIC 0.06 0.00 blup 40 0.02 9.5e-04 5.4 6.2 7.3e-10 -0.45 0.02 0.65 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma CEP120 0.10 0.14 blup 70 0.14 2.6e-14 -5.6 5.2 1.7e-07 -0.03 0.01 0.99 TRUE