[Hub]/) : Traits : Lung FVC :

chr5:126,587,995-128,220,643

Best TWAS P=1.2e-13 · Best GWAS P=1.23e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CTC-228N24.3 0.24 0.15 enet 16 0.20 3.4e-16 6.8 -6.6 3.8e-11 -0.97 0.00 1.00 FALSE
2 GTEx Adipose Visceral Omentum CTC-228N24.3 0.24 0.16 enet 19 0.16 1.8e-08 6.8 -5.4 5.3e-08 -0.80 0.00 1.00 FALSE
3 GTEx Adrenal Gland CTC-228N24.3 0.34 0.10 lasso 9 0.09 4.2e-04 6.7 -7.2 7.1e-13 -0.88 0.01 0.98 FALSE
4 GTEx Artery Aorta CTC-228N24.3 0.20 0.04 lasso 8 0.07 7.4e-05 2.3 -6.3 2.4e-10 -0.91 0.14 0.82 FALSE
5 GTEx Artery Coronary CTC-228N24.3 0.31 0.10 lasso 3 0.10 2.9e-04 6.3 -6.3 3.1e-10 -0.86 0.02 0.85 FALSE
6 GTEx Artery Tibial CTC-228N24.3 0.20 0.16 lasso 7 0.14 3.0e-11 6.8 -6.7 1.7e-11 -0.99 0.00 1.00 FALSE
7 GTEx Brain Cerebellar Hemisphere SLC12A2 0.45 -0.01 enet 20 0.01 2.1e-01 5.8 -6.8 1.4e-11 -0.46 0.04 0.35 TRUE
8 GTEx Brain Cerebellum CTC-228N24.3 0.31 0.04 lasso 5 0.12 2.9e-04 6.8 -5.6 2.5e-08 -0.84 0.01 0.96 FALSE
9 GTEx Cells EBV-transformed lymphocytes CTC-228N24.3 0.24 -0.01 enet 26 0.04 2.2e-02 3.2 -6.8 8.3e-12 -0.57 0.04 0.63 FALSE
10 GTEx Cells Transformed fibroblasts CTC-228N24.3 0.24 0.16 enet 26 0.16 8.6e-12 6.8 -5.7 1.0e-08 -0.89 0.00 1.00 FALSE
11 GTEx Colon Sigmoid CTC-228N24.3 0.20 0.22 enet 11 0.23 1.1e-08 6.3 -6.5 8.6e-11 -0.92 0.02 0.98 FALSE
12 GTEx Esophagus Mucosa CTC-228N24.3 0.18 0.14 enet 11 0.14 9.8e-10 6.8 -6.7 1.7e-11 -0.93 0.00 1.00 FALSE
13 GTEx Esophagus Muscularis CTC-228N24.3 0.24 0.08 enet 29 0.14 1.4e-08 6.3 -6.6 4.7e-11 -0.75 0.01 0.99 FALSE
14 GTEx Heart Atrial Appendage CTC-228N24.3 0.22 0.07 lasso 5 0.07 4.1e-04 6.2 -6.8 1.1e-11 -0.87 0.01 0.98 FALSE
15 GTEx Heart Left Ventricle CTC-228N24.3 0.24 0.15 lasso 7 0.19 1.9e-10 5.8 -6.1 1.2e-09 -0.84 0.01 0.99 FALSE
16 GTEx Lung CTC-228N24.3 0.18 0.14 enet 16 0.14 3.2e-11 6.8 -7.4 1.2e-13 -0.95 0.00 1.00 TRUE
17 GTEx Muscle Skeletal CTC-228N24.3 0.25 0.20 lasso 5 0.21 1.6e-20 6.8 -6.8 8.2e-12 -0.95 0.00 1.00 FALSE
18 GTEx Nerve Tibial CTC-228N24.3 0.32 0.18 lasso 10 0.16 1.6e-11 6.3 -6.1 8.8e-10 -0.96 0.01 0.99 FALSE
19 GTEx Pancreas CTC-228N24.3 0.14 0.19 lasso 2 0.17 1.1e-07 6.8 -6.8 1.3e-11 -1.00 0.00 1.00 FALSE
20 GTEx Skin Not Sun Exposed Suprapubic CTC-228N24.3 0.29 0.21 lasso 7 0.22 1.7e-12 6.8 -6.5 7.1e-11 -0.97 0.01 0.99 FALSE
21 GTEx Skin Sun Exposed Lower leg CTC-228N24.3 0.29 0.17 enet 12 0.22 4.3e-18 6.2 -6.4 1.5e-10 -0.90 0.01 0.99 FALSE
22 GTEx Spleen CTC-228N24.3 0.26 0.03 enet 15 0.05 1.8e-02 2.3 -6.0 2.1e-09 -0.66 0.03 0.58 FALSE
23 GTEx Stomach CTC-228N24.3 0.17 0.04 lasso 6 0.08 1.5e-04 5.8 -6.8 8.8e-12 -0.81 0.03 0.93 FALSE
24 GTEx Testis CTC-228N24.3 0.30 0.16 lasso 6 0.14 1.1e-06 6.8 -5.1 2.8e-07 -0.93 0.00 1.00 TRUE
25 GTEx Thyroid CTC-228N24.3 0.31 0.15 enet 32 0.18 4.6e-14 6.8 -6.7 2.9e-11 -0.78 0.00 1.00 FALSE
26 METSIM Adipose CTC-228N24.3 0.17 0.19 lasso 6 0.18 1.9e-26 6.8 -6.7 2.1e-11 -1.00 0.00 1.00 FALSE
27 ROSMAP Brain Pre-frontal Cortex CTC-228N24.3 0.15 0.09 lasso 3 0.12 8.0e-15 6.8 -6.5 6.2e-11 -0.88 0.00 1.00 TRUE
28 The Cancer Genome Atlas Breast Invasive Carcinoma FBN2 0.02 0.03 lasso 4 0.02 1.0e-05 -5.4 -5.2 1.8e-07 -0.18 0.71 0.28 FALSE
29 The Cancer Genome Atlas Breast Invasive Carcinoma FLJ33630 0.05 0.04 enet 14 0.03 2.1e-07 6.8 -7.0 3.0e-12 -0.88 0.00 1.00 FALSE
30 The Cancer Genome Atlas Glioblastoma Multiforme FLJ33630 0.38 0.20 lasso 5 0.17 6.5e-06 6.8 -6.7 2.4e-11 -0.99 0.00 1.00 FALSE
31 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FLJ33630 0.10 0.07 lasso 3 0.08 7.0e-09 6.3 -6.6 4.2e-11 -0.95 0.00 1.00 FALSE
32 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FLJ33630 0.10 0.06 enet 18 0.08 2.0e-09 6.8 -6.2 5.9e-10 -0.79 0.00 1.00 FALSE
33 The Cancer Genome Atlas Brain Lower Grade Glioma FBN2 0.12 0.02 enet 17 0.05 1.7e-06 6.1 -6.6 5.3e-11 -0.53 0.02 0.95 FALSE
34 The Cancer Genome Atlas Brain Lower Grade Glioma FLJ33630 0.19 0.16 enet 4 0.16 1.2e-17 6.8 -6.7 2.3e-11 -1.00 0.00 1.00 FALSE
35 The Cancer Genome Atlas Lung Adenocarcinoma FLJ33630 0.07 0.05 lasso 1 0.04 1.3e-05 6.3 -6.3 2.8e-10 -0.96 0.01 0.99 FALSE
36 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FLJ33630 0.09 0.08 lasso 4 0.09 4.9e-10 6.8 -6.7 2.3e-11 -1.00 0.00 1.00 FALSE
37 The Cancer Genome Atlas Pancreatic Adenocarcinoma FLJ33630 0.08 0.03 lasso 2 0.04 5.7e-03 6.3 -6.9 4.4e-12 -0.90 0.01 0.88 FALSE
38 The Cancer Genome Atlas Prostate Adenocarcinoma FLJ33630 0.08 0.05 blup 70 0.04 4.4e-05 6.3 -6.0 2.4e-09 -0.86 0.00 1.00 FALSE
39 The Cancer Genome Atlas Prostate Adenocarcinoma SLC12A2 0.04 0.02 enet 17 0.02 3.3e-03 6.3 5.4 8.6e-08 0.69 0.01 0.82 FALSE
40 The Cancer Genome Atlas Stomach Adenocarcinoma FBN2 0.09 0.04 blup 159 0.06 4.6e-05 -4.7 -5.5 4.2e-08 -0.25 0.69 0.03 FALSE
41 The Cancer Genome Atlas Stomach Adenocarcinoma FLJ33630 0.07 0.02 blup 70 0.02 1.5e-02 4.6 -5.3 8.9e-08 -0.48 0.12 0.14 FALSE
42 The Cancer Genome Atlas Testicular Germ Cell Tumors FLJ33630 0.26 0.14 lasso 3 0.13 2.2e-05 6.8 -6.7 1.9e-11 -0.99 0.00 1.00 FALSE
43 The Cancer Genome Atlas Thyroid Carcinoma FLJ33630 0.10 0.10 lasso 2 0.09 5.3e-09 6.8 -6.8 1.4e-11 -1.00 0.00 1.00 FALSE