Hub : Genes

SNX24

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.114	0.0330	9.2e-07	0.001	0.060	0.020	0.054	0.015	2.3e-01	7.5e-08	1.3e-03	3.8e-07	5.8e-03
2	GTEx	Artery Aorta	0.090	0.0440	6.9e-03	0.011	NA	0.015	NA	0.017	7.7e-02	NA	4.9e-02	NA	3.8e-02
3	GTEx	Cells EBV-transformed lymphocytes	0.261	0.0900	5.7e-03	0.148	NA	0.042	NA	0.125	1.5e-05	NA	1.6e-02	NA	7.2e-05
4	GTEx	Cells Transformed fibroblasts	0.073	0.0330	1.7e-03	0.039	NA	0.038	NA	0.044	6.7e-04	NA	7.9e-04	NA	3.0e-04
5	GTEx	Nerve Tibial	0.137	0.0372	2.3e-07	0.166	NA	0.171	NA	0.169	7.9e-12	NA	3.6e-12	NA	4.9e-12
6	GTEx	Ovary	0.219	0.0870	3.8e-03	0.020	NA	0.010	NA	0.005	1.0e-01	NA	1.8e-01	NA	2.3e-01
7	ROSMAP	Brain Pre-frontal Cortex	0.136	0.0443	3.8e-06	0.008	0.046	0.040	0.049	0.022	2.8e-02	1.2e-06	6.2e-06	6.6e-07	7.0e-04
8	TCGA	Breast Invasive Carcinoma	0.055	0.0422	7.7e-03	0.010	0.006	0.006	NA	0.003	3.0e-03	2.0e-02	1.8e-02	NA	6.9e-02
9	TCGA	Brain Lower Grade Glioma	0.159	0.0681	4.3e-05	0.050	0.037	0.021	NA	0.043	2.1e-06	4.0e-05	1.7e-03	NA	1.2e-05
10	TCGA	Pancreatic Adenocarcinoma	0.117	0.0800	3.3e-03	0.065	0.056	0.055	NA	0.047	1.1e-03	2.3e-03	2.5e-03	NA	4.8e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bipolar Disorder (2018)	0.5	0.8	3.5	0.1	1.3	1.0	0.0	0.6	0.7	1.9	0.6	0.0	0.9
Bipolar Disorder or Schizophrenia	0.2	0.5	1.3	-0.2	0.2	0.5	0.4	1.1	0.8	0.7	0.8	0.0	1.2
Depressed Affect (Nagel 2018)	0.8	1.8	6.5	-2.5	-1.9	0.5	1.2	0.8	-0.9	-0.8	-1.3	-0.7	1.0
Depression (Nagel 2018)	1.0	1.5	6.0	-2.5	-0.8	1.4	0.7	0.5	-0.5	-0.5	-0.2	-1.9	1.0
Intelligence (Savage-Jansen 2018)	0.4	1.3	5.0	-0.8	1.4	0.6	-0.2	0.8	-1.2	1.4	1.2	-2.2	0.4
Neuroticism (Nagel 2018)	0.7	1.8	5.5	-2.3	-2.3	-0.5	1.2	0.7	-1.3	-1.3	-1.0	-0.3	0.5
Schizophrenia (2018)	0.2	0.3	0.9	-0.3	-0.8	-0.1	0.5	0.9	0.4	-0.6	0.5	0.0	0.8
Schizophrenia vs Biploar Disorder	0.5	0.7	1.5	-0.2	-0.8	-1.0	1.2	1.1	0.6	-0.3	1.0	0.0	0.8
Worry (Nagel 2018)	0.9	1.9	7.6	-1.1	-2.8	-1.7	1.3	0.8	-1.5	-1.1	-0.8	-0.6	0.2
Alzheimer’s Disease (in mother)	0.6	0.7	1.8	-0.1	0.6	-0.1	-1.2	-1.4	-0.1	-0.8	0.4	-0.6	-1.3
Alzheimer’s Disease (in father)	0.2	0.2	0.6	-0.6	0.3	0.1	0.5	0.4	-0.5	0.1	0.8	-0.3	0.3
Alzheimer’s Disease (including proxy)	0.5	0.7	1.9	-0.5	0.3	-0.8	-0.8	-1.0	-0.6	-1.3	0.8	0.1	-1.4
Crohns Disease (2017)	0.5	1.1	2.0	-0.6	-1.3	1.2	1.4	0.9	-0.6	0.9	-0.7	-1.2	1.3
Irritable Bowel Disease (IBD)	0.3	0.7	3.1	0.4	-0.8	0.2	0.7	0.4	-1.8	0.6	-0.5	1.3	0.5
Ulcerative Colitis (UC)	0.6	1.1	5.5	0.4	-0.2	-0.2	-0.1	-0.1	-2.3	0.0	-0.2	2.3	-0.3
Major Depression (MDD)	1.2	1.4	3.6	-1.0	-1.9	-0.1	0.8	0.4	-1.1	-1.4	-1.8	-1.6	0.3
Reaction Time	0.3	0.5	0.9	0.7	-0.2	-0.9	-0.6	-0.6	0.7	0.7	-0.5	0.8	-0.9
Verbal and Numeric Reasoning (VNR)	0.3	0.6	1.5	0.6	1.0	-0.4	-0.5	0.3	-1.2	0.9	1.1	-1.0	-0.1
Breast Cancer	1.5	3.6	15.4	3.9	1.2	-0.8	-0.7	-0.2	1.7	2.1	1.7	2.7	-0.2
Ovarian Cancer	0.5	0.6	2.0	1.3	-0.6	-0.4	0.0	0.2	-1.4	0.4	-0.5	1.2	-0.5
Prostate Cancer	0.3	0.5	1.3	-0.6	0.1	0.7	-0.7	-1.2	0.3	-0.2	-1.0	0.6	-0.7
Age at First Birth	0.6	0.9	3.0	0.9	1.4	-0.5	-0.6	-0.4	1.7	0.9	1.3	0.0	-0.5
Bipolar Disorder (2011)	0.4	0.4	1.0	-1.0	0.0	0.4	-0.7	-0.7	0.9	-0.5	-0.5	0.0	-0.3
Body Mass Index (BMI) (2010)	1.0	1.3	4.2	-1.7	-2.0	-1.4	1.5	1.0	-0.3	-0.2	-0.3	-0.7	0.5
Coronary Artery Disease (CAD)	0.4	0.4	1.3	0.0	-0.9	-1.1	0.3	-0.1	-0.9	0.0	-0.9	-0.1	-0.5
Crohns Disease (2012)	0.5	0.7	2.0	-0.1	0.1	1.0	1.2	1.1	0.7	1.0	0.2	0.0	1.4
Mean Putamen Volume	0.8	0.9	2.2	-1.5	-1.1	-0.6	1.0	0.9	-0.3	-1.0	0.2	-1.3	0.9
Fasting Glucose	0.2	0.2	0.6	-0.2	-0.2	-0.8	0.5	0.5	-0.2	0.1	0.5	-0.6	0.5
HbA1C	2.5	2.7	7.3	-2.1	-1.4	1.4	1.7	1.2	-2.7	-0.9	-0.3	-2.3	1.1
HDL Cholesterol	2.0	3.4	7.8	-0.1	-1.5	0.6	2.8	2.6	-0.6	1.2	1.2	-2.5	2.7
LDL Cholesterol	0.3	0.5	1.8	0.7	0.3	-0.4	0.5	0.7	1.1	-0.3	1.4	-0.5	0.5
Lupus	0.7	1.0	2.4	-1.1	-1.6	-0.9	0.4	0.1	1.0	-1.0	-1.3	-1.3	-0.1
Neuroticism (2016)	0.3	0.5	1.4	-0.3	-1.2	-0.4	1.0	0.6	-0.0	0.9	-0.5	0.8	0.3
Primary Biliary Cirrhosis	0.9	1.2	4.1	-0.6	-1.9	-0.2	0.6	-0.4	-2.0	-1.1	-1.6	0.3	0.0
Rheumatoid Arthritis	0.3	0.4	1.3	0.6	-0.1	-1.2	0.6	0.7	0.2	0.3	0.6	0.0	0.9
Schizophrenia (2014)	0.1	0.2	0.7	0.0	-0.0	-0.0	0.2	0.6	0.9	-0.3	0.5	0.0	0.6
Triglycerides	1.7	2.7	7.4	0.2	0.7	-1.2	-2.6	-2.3	0.7	-0.9	-0.6	2.1	-2.7
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.3	0.8	-0.5	0.1	0.8	0.8	-0.3	0.9	1.1	0.3	0.7
Ulcerative Colitis	0.2	0.3	1.8	0.7	-0.2	-0.2	0.2	0.4	-1.3	0.0	0.4	0.0	0.3
Blood Eosinophil Count	0.2	1.4	2.7	1.5	1.3	-1.2	0.9	1.1	1.6	0.9	1.6	0.1	0.6
Blood Platelet Count	0.4	4.8	13.8	2.1	-0.4	-2.3	3.0	3.7	1.1	1.4	2.5	-0.8	2.2
Blood Red Count	0.2	2.4	5.3	2.3	1.7	0.0	-1.5	-0.9	-1.3	2.1	0.7	2.3	-0.8
Blood White Count	2.0	14.7	43.3	2.2	-1.4	-1.2	6.1	6.6	-0.6	4.0	4.1	-1.2	4.8
Heel T-Score	0.6	4.9	16.6	-0.1	2.1	3.2	-2.7	-1.6	-4.1	2.4	-1.2	-0.5	-0.4
BMI	0.3	1.9	5.8	-1.8	-2.4	-1.1	2.1	1.4	0.9	-0.0	-0.3	0.6	1.1
Height	0.2	2.9	23.2	-4.8	0.4	0.4	-0.3	0.1	-1.8	-0.0	-1.2	0.6	0.7
Waist Hip Ratio (WHR)	1.0	4.6	11.2	-2.2	-3.3	0.9	2.7	1.7	-1.0	-0.9	-0.6	-3.3	2.4
Systolic Blood Pressure	2.3	11.6	82.4	-2.3	-3.5	0.9	2.3	1.2	-9.1	0.1	-1.6	-1.9	1.5
Smoking Status	0.7	1.6	4.0	-1.1	-2.0	0.9	1.9	1.6	-1.2	0.3	-0.2	-0.3	1.6
Allergy or Eczema	0.2	0.4	1.7	-0.3	0.2	-0.0	0.8	0.6	-0.4	-0.2	0.9	-1.3	0.7
Cardiovascular Disease	0.8	2.6	9.0	-1.1	-2.7	-1.7	0.9	-0.0	-3.0	-2.0	-0.8	-0.5	-0.5
Hypothyroidism (self reported)	1.0	2.2	6.6	1.5	2.4	1.3	-1.5	-0.3	1.0	1.6	0.1	2.6	0.2
Respiratory disease	0.2	0.5	1.4	1.1	0.1	0.4	0.5	0.4	-0.3	1.0	1.2	-0.2	0.5
Type 2 Diabetes (T2D) (2018)	1.8	3.4	8.3	0.0	-2.9	-2.4	-1.0	-2.3	1.3	-0.7	-2.4	0.8	-2.2
Lung FEV1/FVC ratio	0.4	1.9	6.4	-2.5	0.5	0.8	-0.3	-0.6	2.0	-1.1	-1.5	-1.7	0.7
Lung FVC	2.5	12.5	30.1	-4.0	0.4	1.9	-5.1	-5.5	-1.4	-4.0	-3.6	-1.1	-4.2
Neuroticism	1.2	2.9	8.7	-2.9	-3.0	-1.4	1.2	0.2	-1.5	-1.4	-1.8	-1.1	-0.1
Chronotype (morning person)	0.5	1.1	3.1	-1.2	0.0	0.9	0.9	0.9	-0.8	-1.8	0.2	-1.4	1.2
Hair Pigment	0.1	2.4	5.0	1.9	0.5	-2.2	-1.2	-0.7	2.1	-1.0	0.5	2.2	-1.6
Tanning	0.1	0.7	2.5	-0.2	-0.3	-1.0	0.1	0.3	1.6	-0.2	1.4	0.8	0.2
Hand grip strength (left)	0.4	1.1	3.8	-1.9	-0.3	0.9	0.3	0.3	0.5	-1.3	0.9	-1.9	0.5
Number of treatments/medications taken	0.6	1.1	3.9	0.4	-1.6	-1.3	1.0	0.9	-2.0	0.4	-0.4	0.1	0.9
Average weekly spirits intake	2.2	2.7	7.9	1.5	0.8	-2.8	-1.0	-1.1	1.5	0.4	1.6	2.3	-1.9
Sensitivity / hurt feelings	2.1	3.6	13.4	-0.7	-1.8	-3.7	-0.8	-1.5	1.5	-2.3	-1.1	1.6	-2.0
Frequency of depressed mood in last 2 weeks	1.2	1.7	6.0	-1.7	-1.7	-0.1	1.5	1.1	-0.1	-0.0	0.2	-2.5	1.2
Hearing difficulty/problems: Yes	1.4	2.1	6.1	-0.6	-2.5	-2.5	0.8	-0.4	2.1	-0.5	-1.4	-0.3	-0.9
Relative age of first facial hair	1.4	2.8	6.2	0.1	-1.3	-2.2	-1.6	-2.2	0.5	-2.5	-0.8	1.0	-2.4
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	3.5	1.2	-0.2	0.2	-0.0	0.2	-1.9	0.9	0.2	0.5	-0.0
Ever used hormone-replacement therapy (HRT)	0.6	0.8	2.5	0.2	-0.7	1.1	-0.6	-1.0	-1.6	-0.4	-1.0	0.8	-0.6
Ever had hysterectomy (womb removed)	1.5	1.7	6.1	-2.5	-2.1	0.1	0.1	-0.6	0.2	-1.8	-1.1	-0.9	-0.5
Systolic blood pressure, automated reading	1.4	4.2	36.9	-1.1	-1.5	-0.1	0.4	-0.1	-6.1	0.7	-0.9	0.1	0.3
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	6.9	-0.5	-2.6	-0.8	1.3	0.9	-1.5	-0.4	-0.3	-0.5	0.7
Angina	0.4	0.5	2.4	0.3	-0.8	0.3	0.1	0.1	-1.2	1.6	-0.4	0.3	-0.1
Medication for hormone replacement therapy	0.9	1.0	2.6	1.1	0.6	0.9	-1.6	-1.5	-0.6	-0.4	-1.0	0.5	-0.7
Vitamin and mineral supplements	0.2	0.3	0.9	0.4	-0.6	-0.1	1.0	0.8	-0.2	-0.2	0.4	0.3	0.5
Supplements: Zinc	1.5	1.6	5.1	1.1	-0.5	-0.8	-1.3	-1.7	0.1	-0.1	-0.7	2.3	-1.9
Medication: Co-codamol	0.8	1.0	2.3	-0.1	-0.9	-1.0	1.2	1.3	1.5	0.6	0.4	-0.3	1.2
Medication: Metformin	1.4	1.9	5.3	-1.7	-2.1	-1.1	-0.7	-1.6	0.4	-0.7	-2.3	-0.9	-1.0
Diabetes (father)	0.4	0.5	1.5	-0.4	0.4	0.7	0.6	0.8	1.2	0.2	0.4	-0.6	1.0
Diabetes (mother)	2.5	3.2	12.5	1.6	0.6	-0.7	1.6	1.9	-0.0	3.5	2.7	0.6	1.6
Severe depression (siblings)	1.2	1.4	4.2	0.0	-1.4	-1.2	-0.1	-0.7	-1.5	-2.0	-0.7	-0.8	-1.4
Pack years adult smoking proportion	0.8	1.3	6.9	-2.6	-0.3	-0.4	-0.5	-0.8	0.3	-1.9	-0.6	-0.6	-0.1
Impedance of leg (right)	0.7	3.2	7.3	0.5	0.4	0.2	-2.7	-2.4	-1.9	-2.1	-1.6	-1.8	-2.1
Leg fat-free mass (left)	0.4	2.0	10.4	-3.2	-1.5	0.3	1.7	1.3	0.3	0.2	-0.7	0.7	1.5
Trunk fat percentage	0.2	0.9	4.5	-0.5	-1.5	-0.9	-0.1	-0.3	-0.2	-0.6	-2.1	0.9	-0.2
Hand grip strength (right)	0.4	1.1	3.7	-1.8	0.3	1.9	0.0	0.1	1.4	-0.1	0.3	-1.2	0.4
Townsend deprivation index at recruitment	0.8	1.1	2.1	-1.1	-1.3	-0.4	1.3	1.1	-0.3	1.4	-0.4	-0.8	1.4
Current tobacco smoking	1.2	2.0	4.8	-0.2	-0.2	1.7	1.7	1.9	-0.5	1.2	1.6	-1.1	2.2
Average weekly fortified wine intake	0.6	0.7	2.6	0.5	-0.9	-0.3	1.2	1.0	-1.6	0.6	-0.3	0.9	0.3
Maternal smoking around birth	1.8	2.6	7.0	-0.2	-0.5	0.6	2.6	2.6	0.6	1.7	2.2	-0.4	1.8
Fed-up feelings	1.8	3.3	9.3	-2.7	-3.1	0.1	1.8	1.1	-0.8	-1.9	-1.7	-1.7	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	4.2	-1.8	-0.7	1.1	1.3	1.3	-0.3	0.5	0.2	-2.0	1.8
Relative age voice broke	1.0	1.6	6.9	1.7	0.2	-2.6	-0.5	-0.5	1.3	-0.9	0.9	1.0	-1.1
Taking other prescription medications	0.9	1.4	3.6	0.7	-1.9	-1.5	1.7	1.6	-0.3	1.3	0.0	-0.1	0.9
Age when periods started (menarche)	0.7	1.6	5.2	0.2	-1.4	-2.3	1.6	1.2	1.5	-0.7	0.3	-0.8	1.1
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.3	-1.5	0.5	0.5	-1.1	-1.2	0.6	-0.4	-0.6	0.1	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	2.8	-1.3	0.2	1.6	-0.0	0.3	0.1	1.7	-0.5	-1.3	0.5
Tinnitus: Yes, but not now, but have in the past	1.8	1.9	5.3	-1.6	-1.6	1.7	-0.4	-0.8	-0.9	-1.6	-2.3	-1.4	0.0
Qualifications: CSEs or equivalent	0.5	0.6	1.6	0.0	1.0	-0.8	-1.3	-0.7	0.7	0.6	0.1	0.9	-0.9
Serious illness, injury or assault to yourself	1.1	1.3	2.8	0.2	0.7	-0.0	-1.4	-1.2	1.7	1.6	-0.6	1.5	-1.1
High blood pressure	1.1	3.2	13.3	-0.7	-3.1	-1.6	1.5	0.4	-3.6	-1.2	-1.2	-0.6	-0.1
Hayfever, allergic rhinitis or eczema	0.2	0.4	2.0	0.1	0.5	-0.3	0.4	0.4	-0.0	0.4	1.2	-1.4	0.3
Multivitamins +/- minerals	0.5	0.6	1.5	0.4	0.8	-1.1	-1.2	-1.0	0.6	-0.1	0.2	0.5	-1.0
Stomach or abdominal pain in last month	0.5	0.7	2.2	-0.7	-1.1	0.9	0.9	0.4	-0.3	-0.4	-0.6	-1.5	0.6
Supplements: Glucosamine	2.7	3.5	9.1	-0.1	0.1	-0.1	-3.0	-3.0	-0.2	-1.7	-2.5	1.3	-2.5
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	2.9	-0.1	-0.2	0.7	0.8	0.8	-1.7	0.7	-0.3	-0.7	1.7
Medication: Atenolol	0.6	0.7	1.6	0.9	-1.1	0.6	1.1	0.8	-1.3	-0.5	-0.8	0.0	0.8
Medication: Levothyroxine sodium	1.1	1.9	8.0	-0.1	1.4	1.7	0.3	1.1	-0.2	2.8	0.4	2.0	1.1
Sitting height	0.9	6.4	29.4	-5.4	-0.0	2.5	-1.9	-1.9	-3.5	-1.3	-2.6	-0.3	-0.8
Chronic bronchitis/emphysema (father)	1.6	1.8	5.1	0.5	-0.6	-2.2	2.0	2.3	0.4	0.8	1.5	-0.1	1.1
High blood pressure (mother)	0.8	1.1	6.3	-0.3	-1.3	-0.0	0.4	0.4	-0.7	-1.0	-0.9	-2.5	0.3
Body mass index (BMI)	0.4	1.5	4.4	-1.4	-1.4	-0.3	2.1	1.7	0.6	0.6	-0.2	0.4	1.6
Impedance of leg (left)	0.6	2.9	6.9	0.9	0.5	0.1	-2.6	-2.4	-1.4	-2.1	-1.6	-1.6	-1.9
Leg predicted mass (left)	0.4	2.1	10.7	-3.3	-1.5	0.3	1.7	1.3	0.3	0.3	-0.7	0.7	1.5
Trunk fat mass	0.3	1.2	4.7	-1.7	-1.7	-0.7	0.4	0.1	-0.4	-0.5	-2.2	1.0	0.1
Waist circumference	0.5	1.9	6.3	-2.5	-1.8	0.3	1.9	1.5	0.1	0.4	-0.9	0.1	1.6
Number of incorrect matches in round	0.4	0.6	1.3	0.1	0.1	-0.2	-1.0	-1.0	0.5	-0.9	-1.0	0.7	-1.1
Past tobacco smoking	0.5	0.9	2.7	1.1	1.6	1.1	-1.3	-0.8	0.9	0.1	-0.4	-0.4	-0.3
Alcohol usually taken with meals	0.5	0.8	2.9	1.7	0.5	-1.0	-0.5	-0.5	0.8	-0.1	0.9	0.1	-1.4
Nervous feelings	0.6	1.2	4.7	-0.3	-2.2	-2.0	0.8	0.5	0.7	-1.1	-0.5	-0.3	0.3
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.3	5.7	-0.9	-1.1	0.3	2.0	2.1	-0.8	1.4	1.3	-1.8	2.4
Hearing difficulty/problems with background noise	1.3	2.1	5.8	1.0	-1.1	-2.4	-0.7	-1.4	1.2	-1.5	-1.4	-0.4	-2.1
Hair/balding pattern: Pattern 2	1.0	1.3	7.0	-0.1	-0.5	-1.4	-0.6	-0.7	2.6	-0.8	0.0	1.5	-0.2
Had menopause	0.4	0.5	1.1	-1.0	-0.5	1.0	-0.1	-0.4	-0.7	-0.8	-0.9	-0.0	-0.3
Had other major operations	0.8	1.0	3.2	0.1	-1.4	-1.2	1.8	1.2	0.1	1.0	0.4	0.2	0.6
Forced vital capacity (FVC)	2.0	7.7	15.1	-3.7	0.1	2.7	-3.7	-3.9	-2.2	-2.6	-2.9	-0.7	-2.7
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	1.9	-1.4	0.6	1.3	-0.3	0.0	0.6	1.4	-0.4	-1.0	0.5
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.3	-0.7	-0.1	0.2	-1.1	-1.1	-0.5	-0.7	-0.8	1.2	-0.7
Qualifications: None of the above	1.2	2.6	10.4	-1.5	-3.2	-0.7	2.1	0.8	-0.6	-2.1	-1.1	-1.0	0.9
Financial difficulties in last 2 years	1.7	2.3	5.0	0.3	-0.7	-1.9	-1.6	-2.1	0.6	-2.1	-0.9	0.9	-2.2
Mouth/teeth dental problems	0.4	0.6	1.6	0.4	0.2	1.3	0.9	0.8	0.2	1.1	0.1	-0.2	1.2
Heart attack	0.5	0.6	1.5	-1.2	-0.5	0.6	0.3	-0.1	-1.1	-0.7	-0.9	-0.7	0.8
Allergy	0.1	0.3	2.4	0.3	0.1	-0.3	-0.3	-0.2	-0.2	-0.2	-0.3	1.6	-0.4
Pain all over the body in last month	0.5	0.5	2.5	0.0	-1.0	0.2	0.8	0.6	-1.6	-0.1	-0.6	-0.2	0.4
Diabetes (self-reported)	0.6	0.9	2.8	0.5	-1.7	-1.4	-0.2	-1.0	0.4	-0.4	-1.3	0.7	-0.6
Hayfever/allergic rhinitis (self-reported)	0.3	0.5	2.1	-0.5	1.3	0.1	-0.6	-0.1	1.4	-0.2	0.2	0.1	0.2
Medication: Ramipril	1.3	1.7	4.3	-2.0	-2.1	0.8	0.4	-0.5	-1.5	-1.4	-1.4	-1.0	0.2
Medication: Simvastatin	0.1	0.2	0.8	-0.4	-0.1	0.3	0.3	0.7	-0.9	0.4	0.1	0.2	0.5
Fluid intelligence score	0.3	0.6	2.3	0.7	1.5	-0.3	-0.8	-0.1	-0.8	0.6	1.0	-0.1	-0.4
Illnesses of siblings	0.9	1.2	8.0	1.1	1.1	0.6	-0.7	-0.3	2.8	0.4	0.1	0.6	-0.2
Neuroticism score	1.4	2.8	9.7	-2.0	-3.1	-2.1	0.9	-0.0	-1.7	-1.8	-1.7	-0.6	-0.3
Weight	0.4	2.0	10.2	-3.2	-1.7	0.1	1.5	1.1	-0.3	-0.0	-1.3	0.4	1.2
Impedance of arm (right)	0.4	1.7	5.0	2.2	0.6	-0.2	-2.2	-1.7	-0.8	-0.2	-1.2	0.0	-1.5
Arm fat percentage (right)	0.2	0.9	2.3	-0.3	-1.5	-0.6	1.5	1.1	0.3	0.6	-0.9	0.5	1.0
Trunk fat-free mass	0.4	2.4	15.8	-4.0	-0.5	0.8	1.6	1.3	-0.0	0.6	-0.0	0.5	1.4
Hip circumference	0.2	1.0	3.1	-1.8	-1.0	-0.6	0.6	0.3	0.7	0.5	-1.5	1.4	-0.0
Time employed in main current job	2.2	2.6	9.1	2.2	0.6	-3.0	-0.8	-0.9	1.1	-1.0	0.4	2.1	-1.7
Alcohol intake versus 10 years previously	4.6	6.8	12.3	-2.5	-2.3	3.5	3.4	2.8	-0.6	1.4	-0.7	-3.2	3.4
Father’s age at death	0.7	1.0	1.9	-0.6	0.4	-0.0	1.3	1.4	0.3	1.2	0.8	-1.4	1.1
Worrier / anxious feelings	2.2	4.2	12.6	-0.1	-3.5	-3.0	3.3	2.4	-0.5	-1.2	0.6	-1.0	1.2
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	4.8	-1.0	-1.5	-0.7	-0.3	-0.6	-1.8	-2.2	-1.3	-1.3	-0.9
Falls in the last year	1.1	1.4	6.7	-2.6	-1.0	0.3	-0.7	-1.3	1.3	-0.2	-1.5	0.1	-0.7
Hair/balding pattern: Pattern 3	1.1	1.7	5.8	2.4	1.0	0.1	-0.4	-0.3	-2.0	0.7	-0.0	2.1	-0.9
Number of live births	1.2	1.7	5.5	-2.3	-0.2	1.0	1.6	1.8	0.4	0.2	0.7	-0.9	1.7
Forced expiratory volume in 1-second (FEV1)	2.1	7.0	14.8	-3.7	0.7	2.7	-3.7	-3.8	-1.1	-2.5	-2.7	-0.7	-2.3
Pulse rate	1.4	2.4	5.1	2.0	-0.0	0.1	1.4	1.8	-0.6	2.0	2.2	-1.4	1.6
Happiness	1.2	1.5	3.5	-1.4	-1.9	-0.5	0.5	-0.1	-1.0	-1.9	-1.4	-1.5	-0.1
Noisy workplace	0.8	1.0	5.8	-0.8	-1.7	-0.4	0.7	0.2	-2.4	-0.2	-0.5	-0.1	0.1
Qualifications: A levels/AS levels or equivalent	0.3	0.7	2.2	0.3	1.5	1.3	-1.2	-0.7	-1.1	0.4	0.2	-0.2	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.1	0.1	0.2	0.7	-0.7	-0.6	-0.9	0.4	-1.1	-0.7	-0.5
Mouth/teeth dental problems: Dentures	0.6	1.1	3.8	0.3	0.2	-0.6	-1.5	-1.6	0.2	-1.0	-0.5	0.1	-1.9
Asthma	0.4	0.9	3.5	0.9	0.0	0.4	0.9	1.1	0.2	1.0	1.9	-0.6	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	3.7	0.3	-0.5	0.2	1.6	1.5	0.9	0.1	1.9	0.1	1.2
Medication: Cholesterol lowering	0.3	0.4	1.3	-0.2	-0.5	-1.1	-0.7	-0.7	0.1	-0.6	-1.1	-0.2	-0.5
Depression (self-reported)	3.2	3.8	9.8	0.4	1.5	0.0	2.2	2.9	0.8	2.8	3.1	0.3	2.1
Medication: Lansoprazole	2.1	2.4	11.8	0.5	-3.4	-2.2	1.8	1.2	-1.2	-0.8	-0.3	0.7	-0.0
Prospective memory result	1.0	1.2	3.3	-0.2	-1.2	-0.5	1.8	1.6	1.8	-0.2	0.2	-0.8	0.7
Lung cancer (father)	1.4	1.6	8.5	-0.7	0.1	0.2	-1.4	-1.4	2.9	0.0	-1.3	0.2	-1.0
Illnesses of mother	0.3	0.4	1.4	0.0	0.2	-0.0	-0.6	-0.7	-0.5	-1.0	-0.5	1.2	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	2.2	7.1	14.7	-3.5	1.3	2.9	-3.8	-3.8	-1.1	-2.5	-2.5	-0.9	-2.4
Pulse wave Arterial Stiffness index	0.5	0.6	2.9	0.8	-0.0	0.3	0.3	0.8	-1.7	0.5	-0.2	-0.4	0.9
Impedance of arm (left)	0.5	2.5	7.5	2.1	0.7	0.1	-2.7	-2.2	-1.2	-0.7	-1.6	-0.1	-1.8
Arm fat mass (right)	0.3	1.1	2.6	-1.6	-1.4	-0.3	1.6	1.2	0.5	0.5	-0.8	0.6	1.1
Trunk predicted mass	0.4	2.4	15.3	-3.9	-0.5	0.8	1.6	1.4	-0.0	0.6	0.0	0.6	1.5
Standing height	0.4	3.5	18.9	-4.3	-0.7	0.9	-1.2	-1.3	-1.5	-1.6	-2.5	0.0	-0.8
Length of working week for main job	0.6	0.7	2.4	0.5	-0.9	-0.6	-0.4	-1.0	0.6	-1.5	-0.4	0.7	-1.0
Exposure to tobacco smoke at home	0.3	0.4	0.7	-0.6	-0.9	-0.8	0.4	0.4	0.6	0.2	-0.4	0.6	0.7
Breastfed as a baby	0.2	0.3	0.8	-0.4	0.4	0.9	0.1	0.4	-0.6	0.7	0.2	0.6	0.4
Tense / ‘highly strung’	0.6	1.0	3.5	-1.9	-1.7	-1.0	0.6	0.4	-0.8	-1.1	-0.2	-0.5	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.5	1.5	-0.7	-1.1	-0.3	1.0	0.8	-1.2	0.2	-0.2	0.2	0.3
Hair/balding pattern: Pattern 4	2.2	5.3	21.7	2.9	0.3	-4.7	0.8	1.4	0.6	-0.1	3.3	2.9	0.7
Birth weight of first child	0.5	0.9	2.7	-0.8	-0.2	1.6	-0.6	-0.6	-1.1	-0.6	-1.3	-1.1	-0.4
Peak expiratory flow (PEF)	1.8	4.2	7.1	-2.0	-0.2	2.0	-2.4	-2.7	-2.3	-2.6	-2.3	-0.9	-1.5
Pulse wave reflection index	0.4	0.5	1.1	0.5	0.4	-0.8	-0.7	-0.7	0.6	-1.1	-0.6	0.9	-0.7
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.4	-0.6	-0.7	-1.2	1.1	0.9	-0.1	0.1	0.1	-0.4	0.6
Loud music exposure frequency	0.7	0.8	1.8	0.5	-0.7	-0.2	1.3	1.3	0.5	0.1	0.6	-1.1	1.3
Qualifications: O levels/GCSEs or equivalent	1.8	2.9	8.5	1.3	1.2	-0.3	-2.9	-2.8	0.1	0.1	-0.7	1.3	-2.8
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	2.7	-1.4	0.1	-0.2	-1.3	-1.2	-0.1	-1.6	-1.3	-0.5	-1.1
Blood clot in the leg (DVT)	1.6	2.1	5.5	-0.8	-0.7	-0.7	-1.6	-1.9	-0.6	-1.8	-2.3	0.9	-1.8
Medication: Paracetamol	2.0	3.4	8.0	-0.2	-1.1	0.3	2.6	2.8	-0.3	0.7	1.6	-2.7	2.7
Headache pain in last month	1.6	2.7	10.8	-0.0	-3.3	-0.4	2.2	1.5	-1.7	-1.8	0.2	-1.0	1.3
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	8.5	-0.4	1.6	2.9	0.2	0.8	0.6	1.1	1.1	-0.4	1.1
Glaucoma (self-reported)	0.5	0.6	1.2	-0.8	-1.0	-0.8	1.1	0.9	-0.2	0.5	0.3	-0.8	0.4
Gout (self-reported)	0.3	0.5	1.5	-0.7	-1.0	0.1	-0.3	-0.3	-1.1	-0.0	-1.2	0.3	-0.4
Hypothyroidism/myxoedema (self-reported)	1.5	2.8	7.5	1.7	2.5	1.1	-1.2	0.1	1.5	2.6	0.1	2.7	0.0
Medication: Amlodipine	0.5	0.7	3.3	0.4	-1.0	-0.9	0.4	0.1	-1.8	0.1	-1.3	-0.1	-0.3
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.6	-1.2	-0.3	0.9	0.7	0.4	-1.0	-0.4	-0.7	-1.6	1.0
Birth weight	0.7	1.5	9.8	-3.1	0.1	1.5	-0.4	-0.3	-0.5	-1.1	-0.4	-0.6	-0.1
Chronic bronchitis/emphysema (mother)	1.0	1.2	3.6	-0.6	0.4	0.0	1.4	1.5	-0.3	1.4	1.9	-0.4	1.2
High blood pressure (siblings)	1.6	2.4	13.0	-1.5	-1.4	-0.7	1.6	1.0	-3.6	0.4	-0.1	-1.4	0.2
Forced vital capacity (FVC), Best measure	2.1	7.5	18.3	-2.9	1.4	2.4	-4.3	-3.9	-1.9	-2.6	-2.3	-0.0	-3.0
Body fat percentage	0.2	0.7	3.6	-0.6	-1.5	-0.6	0.3	0.0	-0.3	-0.5	-1.9	0.6	0.2
Leg fat percentage (right)	0.3	0.9	2.8	-1.2	-1.6	-0.2	0.9	0.6	-0.6	-0.6	-1.7	-0.3	0.7
Arm fat-free mass (right)	0.5	2.8	17.3	-4.2	-1.3	0.6	1.7	1.4	-0.5	-0.4	-0.7	0.3	1.5
Exposure to tobacco smoke outside home	0.3	0.4	1.5	0.2	-1.2	-0.0	0.8	0.5	-0.1	1.1	-0.4	0.1	0.5
Comparative body size at age 10	1.6	4.5	9.4	0.9	1.3	2.7	1.9	2.7	-1.2	2.7	2.2	1.0	3.1
Number of full brothers	1.1	1.4	6.5	-0.4	-2.5	-1.1	1.3	0.5	-0.0	-1.4	-0.9	-1.2	-0.1
Worry too long after embarrassment	0.8	1.3	3.6	0.0	-1.9	-1.9	0.1	-0.4	-1.2	-1.3	-0.7	0.6	-1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.9	-0.0	-0.4	1.0	-0.0	0.0	-0.3	-0.3	-0.8	-0.3	-0.0
Wheeze or whistling in the chest in last year	0.4	0.7	3.7	-0.7	-1.9	-1.1	0.6	0.3	-0.7	0.1	-0.7	-0.3	-0.2
Number of children fathered	0.9	1.0	3.3	-1.6	-1.8	-0.2	0.1	-0.2	-0.2	-1.2	-1.5	-0.8	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	2.5	0.5	0.9	-1.5	-1.0	-0.6	1.6	0.0	1.4	-0.2	-0.9
Age at first live birth	0.7	1.3	3.1	0.5	0.3	-1.4	-1.4	-1.4	1.2	-1.3	-0.2	-0.1	-1.7
Pulse wave peak to peak time	0.5	0.6	2.3	-1.1	-0.1	-0.3	-0.4	-0.9	1.5	-0.6	-0.0	0.3	-1.0
Health satisfaction	1.4	1.8	6.0	-2.4	-2.3	-0.1	0.7	0.1	-0.6	-0.6	-0.9	-2.2	0.3
Shortness of breath walking on level ground	1.2	1.4	5.3	-1.9	-1.4	0.1	0.8	0.5	2.3	0.2	0.3	-1.3	1.0
Qualifications: College or University degree	0.3	0.8	2.8	0.6	1.2	-0.1	-1.0	-0.3	-1.2	1.7	-0.3	0.8	-0.4
Eye problems/disorders: None of the above	1.2	1.4	5.9	1.7	1.0	-0.7	-0.9	-0.9	2.4	-0.2	0.3	1.3	-0.6
Mouth/teeth dental problems: Loose teeth	0.4	0.5	2.1	-0.2	-0.1	-0.7	-0.4	-0.7	1.5	-0.1	0.1	0.5	-1.1
Emphysema/chronic bronchitis	0.3	0.3	1.1	0.2	-0.7	-0.2	-0.5	-0.5	0.3	-0.4	-1.1	0.6	-0.0
Medication for pain relief, constipation, heartburn	0.7	1.3	3.1	-0.4	1.4	-0.0	-1.6	-1.8	0.9	-0.0	-0.8	1.0	-1.5
Neck or shoulder pain in last month	1.3	1.8	4.6	-1.3	-2.1	-1.1	1.7	1.1	1.0	-1.8	0.3	-1.3	0.4
Medication: Blood pressure	1.2	2.0	8.1	-0.7	-2.1	-1.4	0.2	-0.6	-2.8	-1.4	-1.5	-0.1	-0.7
Angina (self-reported)	0.4	0.5	2.7	0.1	-0.7	0.5	0.2	0.2	-1.2	1.6	-0.3	0.4	0.1
Migraine (self-reported)	1.1	1.3	4.5	0.6	-2.1	-0.2	1.4	0.7	1.5	-0.7	-0.1	-1.5	0.6
Medication: Ibuprofen	0.7	0.8	2.5	-0.3	-1.3	-0.1	1.6	1.2	0.2	-0.6	1.2	0.2	1.0
Medication: Allopurinol	1.2	1.6	4.1	0.6	-0.2	-1.0	-2.0	-1.8	-0.3	-0.5	-0.9	1.5	-2.0
Medication: Omeprazole	1.0	1.2	3.0	-1.3	-1.2	1.3	0.8	0.2	-1.7	-1.4	-0.6	-0.9	0.8
Medication: Seretide 50 evohaler	0.4	0.4	2.5	-1.6	-0.2	0.0	0.3	0.1	1.2	0.1	-0.3	-0.4	0.1
Mean time to correctly identify matches	0.4	0.7	2.1	0.9	0.1	-1.5	-0.7	-0.7	0.9	0.2	-0.5	0.9	-1.3
Heart disease (mother)	0.7	0.9	2.9	0.5	0.8	1.5	0.2	0.3	-1.6	1.7	-0.0	0.2	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.0	3.4	-0.6	0.7	1.9	0.3	0.6	1.6	0.9	0.3	-0.3	1.5
Whole body fat mass	0.2	1.0	2.8	-1.7	-1.5	-0.5	0.7	0.4	-0.1	-0.3	-1.6	0.8	0.5
Leg fat mass (right)	0.3	1.3	4.8	-2.2	-1.7	0.0	1.2	0.7	-0.1	-0.4	-1.7	0.1	0.9
Arm predicted mass (right)	0.5	2.8	17.6	-4.2	-1.5	0.5	1.8	1.3	-0.3	-0.3	-0.7	0.1	1.5
Pulse rate, automated reading	1.0	3.1	8.3	1.9	-0.6	1.9	1.4	1.5	-2.3	0.7	0.8	-2.9	2.1
Alcohol intake frequency.	0.1	0.3	2.0	0.3	0.2	1.4	0.1	0.3	-0.3	0.1	-0.6	-0.4	0.7
Comparative height size at age 10	0.4	2.2	10.0	-3.2	-1.1	0.9	-0.1	-0.3	-2.3	-0.6	-1.6	-1.1	-0.1
Number of full sisters	1.8	2.2	11.4	-1.7	-1.9	-1.2	0.2	-0.4	0.0	-3.4	-1.2	-0.6	-0.7
Suffer from ‘nerves’	1.7	2.7	5.2	-1.6	-2.1	0.3	2.3	2.2	-1.4	0.8	-0.1	-1.4	2.3
Overall health rating	0.6	1.4	7.7	-0.4	-2.8	-1.0	1.0	0.1	-1.6	-0.1	-0.7	-0.8	-0.2
Chest pain or discomfort	0.4	0.5	1.8	0.7	-0.2	-1.1	-0.1	0.2	1.3	0.2	1.0	0.2	-0.6
Had major operations	1.1	1.3	5.2	1.6	0.1	-0.5	-1.1	-1.0	-1.1	-0.2	-0.9	2.3	-0.9
Age at last live birth	0.2	0.3	1.6	-0.2	0.8	-0.1	-0.3	-0.1	1.3	0.2	0.8	-0.1	-0.1
Family relationship satisfaction	1.1	1.4	6.4	-2.5	-1.4	-0.9	0.3	-0.2	-0.1	-1.5	-0.9	-0.9	-0.5
Leg pain on walking	0.5	0.6	2.1	-1.1	-1.5	-0.2	-0.1	-0.4	-1.1	-0.4	-1.2	0.2	-0.3
Qualifications: NVQ or HND or HNC or equivalent	2.0	2.4	4.8	1.4	-1.1	-1.5	2.2	2.0	1.8	0.6	2.1	-0.3	1.2
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.2	0.2	0.1	-0.2	0.1	0.4	-0.2	-0.2	0.4	0.5	0.4
Illness, injury, bereavement, stress in last 2 years	1.2	1.5	4.8	0.5	-0.1	0.4	1.9	2.1	-1.0	-0.1	0.9	-0.0	2.2
Medication: Aspirin	0.1	0.1	0.5	0.1	-0.6	-0.3	-0.2	-0.0	-0.2	0.1	-0.7	0.1	-0.2
Supplements: Vitamin C	0.5	0.6	3.3	-1.2	0.3	1.8	-0.1	-0.1	-0.4	0.4	0.1	-0.6	0.3
Knee pain experienced in last month	0.6	0.9	3.9	0.5	0.2	-1.6	0.5	0.4	1.1	0.2	0.8	2.0	-0.1
Hypertension (Self-reported)	1.2	3.4	14.5	-0.8	-3.0	-1.9	1.3	0.1	-3.8	-1.5	-1.4	-0.4	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.5	3.0	7.5	-1.5	-2.7	-1.5	-0.3	-1.2	-1.7	-2.1	-2.5	0.8	-1.3
Illnesses of father: Heart disease	1.7	2.4	8.4	-0.1	-0.3	1.3	-1.6	-2.1	-2.9	-0.8	-2.1	0.1	-1.2
Illnesses of siblings: Diabetes	0.5	0.6	2.3	0.7	0.3	-1.5	-0.5	-0.4	1.0	-0.4	0.7	0.8	-0.6
Smoking status: Previous	0.5	0.7	2.1	-0.7	-1.5	-1.0	1.1	0.7	-0.3	-0.2	0.1	1.4	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.0	-0.5	0.1	0.1	-0.8	-1.0	0.5	-0.2	-0.3	1.0	-1.0
Whole body fat-free mass	0.4	2.4	14.7	-3.8	-1.0	0.7	1.8	1.4	0.1	0.3	-0.3	0.6	1.6
Leg fat-free mass (right)	0.4	2.0	8.6	-2.9	-1.3	0.3	1.8	1.5	0.7	0.4	-0.3	0.8	1.6
Arm fat percentage (left)	0.2	0.8	2.5	-0.4	-1.6	-0.6	1.3	1.0	0.2	0.4	-1.1	0.5	0.9
Average weekly red wine intake	0.4	0.6	2.1	-0.7	-0.2	-1.5	-0.2	-0.3	0.5	-1.0	-0.7	-0.4	-1.0
Handedness (chirality/laterality): Left-handed	1.5	1.9	4.1	-2.0	-1.8	1.0	1.0	-0.0	-2.0	0.2	-1.9	-1.3	0.1
Mood swings	1.8	3.3	12.7	-2.6	-3.6	-1.5	1.8	0.9	-0.5	-1.9	-1.3	-1.0	0.7
Loneliness, isolation	1.4	1.9	3.7	-1.7	-1.2	-0.4	1.7	1.6	1.3	1.9	-0.8	-1.1	1.4
Long-standing illness, disability or infirmity	0.9	1.3	3.5	-0.3	-1.4	-1.9	-0.9	-1.3	-1.1	-0.7	-0.8	0.6	-1.5
Ever had bowel cancer screening	0.9	1.0	3.0	1.7	-0.3	-1.5	0.3	0.7	0.8	0.7	0.3	1.6	-0.5
Diabetes diagnosed by doctor	0.9	1.4	4.3	0.2	-2.1	-1.7	-0.1	-1.2	1.0	-0.2	-1.8	0.6	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	2.1	0.4	0.4	1.0	0.9	1.1	-1.2	0.4	1.2	-0.9	1.4
Friendships satisfaction	0.4	0.5	0.9	-0.8	-0.9	-0.5	0.6	0.5	-0.9	-0.8	-0.4	-0.7	-0.1
Qualifications: nursing, teaching	0.8	1.3	3.2	1.4	1.6	-0.7	-1.8	-0.9	0.1	0.5	0.4	1.3	-1.3
Commuting to job workplace: Walk	0.7	0.8	2.0	-0.6	0.4	-0.9	-1.1	-1.4	1.2	-0.1	-0.5	-0.4	-1.2
Eye problems/disorders: Cataract	0.3	0.3	1.2	-0.3	0.0	0.8	0.4	0.3	-1.1	0.9	0.1	-0.4	0.1
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	5.4	0.6	-1.7	-0.3	2.3	2.3	-1.1	0.9	0.7	-0.9	1.9
Medication for cholesterol	1.1	1.6	5.9	0.2	0.4	-1.7	-1.2	-1.2	2.4	-1.2	-0.2	1.1	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.2	0.9	-0.6	-0.2	0.2	0.2	0.5	1.1	-0.5	-0.3	-0.8
Back pain experienced in last month	1.6	2.4	8.5	-1.0	-2.9	-0.6	2.0	1.3	-1.5	-1.6	-0.4	-1.6	0.8
Mineral and other dietary supplements	1.0	1.4	2.4	-1.1	0.9	1.0	1.1	1.5	0.1	1.0	1.5	-1.2	1.5
Breast cancer (self-reported)	0.7	0.8	2.1	-0.9	-0.4	1.5	0.9	0.9	0.2	1.4	-0.1	-0.4	1.1
Asthma (self-reported)	0.4	0.8	2.5	0.8	-0.3	0.4	1.1	1.2	0.3	0.7	1.6	-0.8	1.1
Osteoporosis (self-reported)	0.5	0.7	1.7	-0.0	-0.7	-0.6	1.3	1.1	-0.7	0.9	0.6	-0.9	0.5
Osteoarthritis (self-reported)	0.7	0.9	3.9	1.1	-1.2	-2.0	0.6	0.5	0.2	-0.7	-0.5	1.1	-0.7
Medication: Aspirin	0.1	0.1	0.7	-0.1	-0.4	-0.2	-0.2	0.1	0.2	0.1	-0.9	0.4	0.0
Medication: Gliclazide	0.7	0.8	2.7	-0.1	-0.3	1.1	-0.5	-0.8	-1.2	0.7	-1.7	-0.9	-0.3
Illnesses of father: None of the above (group 1)	0.5	0.7	5.7	0.0	0.3	0.5	0.1	0.1	2.4	-0.2	0.7	-0.2	0.3
Smoking status: Current	1.0	1.6	3.9	-0.1	-0.4	1.4	1.5	1.7	-0.9	1.0	1.3	-1.0	2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.6	9.7	-1.6	0.5	1.6	-2.8	-3.1	-1.0	-1.8	-2.2	-0.4	-2.0
Whole body water mass	0.4	2.4	14.7	-3.8	-1.0	0.6	1.7	1.4	0.1	0.4	-0.3	0.7	1.6
Leg predicted mass (right)	0.4	2.0	9.1	-3.0	-1.4	0.2	1.8	1.4	0.7	0.2	-0.5	0.8	1.5
Arm fat mass (left)	0.3	1.4	3.1	-1.7	-1.7	-0.2	1.8	1.3	0.1	0.4	-0.9	0.6	1.3
Number of self-reported non-cancer illnesses	0.4	0.7	2.2	0.6	-1.3	-1.5	1.0	0.4	-0.8	0.6	0.1	0.3	0.0
Average weekly champagne plus white wine intake	0.4	0.5	2.6	-1.1	-0.4	-0.2	-0.3	-0.2	-1.6	-0.4	-0.1	-0.6	-0.1
Miserableness	0.2	0.3	1.1	-0.8	-0.8	-1.1	0.1	-0.1	-0.5	0.0	-0.2	-0.2	-0.3
Guilty feelings	0.5	0.8	2.2	1.2	1.0	-0.2	-0.6	-0.3	-1.5	0.1	0.7	1.3	-0.6
Wears glasses or contact lenses	1.0	1.1	3.1	1.7	1.4	0.2	0.4	0.5	-1.7	0.5	1.5	0.4	0.6
Ever taken oral contraceptive pill	1.7	1.9	5.2	0.3	-0.6	-2.3	-1.2	-1.5	1.2	-1.0	-1.6	0.9	-2.0
Hearing aid user	1.3	1.4	4.6	-0.9	-0.6	-2.1	-0.5	-0.9	2.0	-1.1	-0.8	0.5	-1.0
Mother’s age at death	0.2	0.2	1.0	0.5	0.2	-0.1	-0.2	-0.5	-1.0	0.4	-0.5	-0.2	-0.4
Financial situation satisfaction	0.6	0.7	2.0	-0.7	-1.4	-1.2	0.3	-0.0	-0.6	-1.3	-0.9	-0.3	-0.5
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.9	-0.2	0.6	0.3	-0.2	-0.0	0.4	0.1	0.9	-0.9	-0.0
Commuting to job workplace: Public transport	0.4	0.4	2.4	0.2	0.8	0.1	-0.2	-0.2	1.5	0.7	0.7	-0.2	-0.0
Eye problems/disorders: Glaucoma	1.1	1.3	3.2	-0.6	-1.4	-0.8	1.8	1.5	-0.9	0.6	0.2	-1.4	1.0
Medication: Blood pressure	1.1	2.0	12.1	-0.8	-1.3	0.9	0.9	0.5	-3.5	-0.0	-1.1	-1.6	0.4
Pain type(s) experienced in last month: Hip pain	0.4	0.5	2.9	-1.7	-0.5	0.3	-0.0	-0.2	-0.4	-0.9	-0.1	-0.7	-0.1
Supplements: Fish oil (including cod liver oil)	1.0	1.3	2.2	0.9	-0.5	-1.2	-1.4	-1.4	0.8	-1.1	-1.3	0.7	-1.5
High cholesterol (Self-reported)	0.2	0.4	2.5	-0.3	-0.4	-1.6	-0.0	-0.3	0.5	-0.2	-0.3	-0.1	-0.8
Medication: Bendroflumethiazide	1.4	2.1	9.9	-0.7	-2.5	-0.3	1.2	0.7	-3.1	-0.6	-1.4	-0.6	0.2
Medication: Paracetamol	1.4	2.2	4.8	-0.9	-1.2	0.6	2.0	2.0	-1.2	0.1	0.9	-2.0	2.2
Medication: Lisinopril	1.0	1.3	5.9	-0.6	-1.0	1.2	0.6	0.2	-2.4	1.0	-1.6	-0.3	0.3
Medication: Atorvastatin	1.0	1.3	4.3	-1.8	-2.1	-0.4	0.6	-0.3	0.0	-0.9	-1.6	-1.1	0.0
Illnesses of father: High blood pressure	1.2	1.4	4.2	-0.7	-1.7	-2.0	0.6	0.3	-1.9	-0.6	-0.8	-1.2	-0.2
Alcohol drinker status: Never	0.5	0.6	4.2	-0.1	0.2	0.2	-0.3	-0.3	-2.1	-0.6	0.2	0.7	-0.5
Ever smoked	0.4	0.6	1.6	-1.3	-0.9	-1.0	1.0	0.8	-0.8	-0.1	0.7	0.4	0.3
Basal metabolic rate	0.4	2.4	13.6	-3.7	-1.2	0.5	1.8	1.5	0.1	0.3	-0.5	0.5	1.6
Leg fat percentage (left)	0.2	0.9	2.4	-1.0	-1.6	-0.2	1.2	0.8	-0.4	-0.5	-1.4	-0.2	0.9
Arm fat-free mass (left)	0.5	2.3	13.8	-3.7	-1.2	0.4	1.8	1.4	-0.0	0.0	-0.4	0.4	1.4
Number of operations (self-reported)	0.7	1.1	5.3	-0.7	-0.9	1.0	0.3	-0.0	-2.3	0.3	-1.2	1.1	0.4
Average weekly beer plus cider intake	0.4	0.6	2.2	-1.0	-0.9	1.1	-0.2	-0.6	-0.9	-0.2	-1.5	0.3	-0.0
Irritability	0.8	1.4	4.5	-0.9	-1.6	-1.3	0.7	0.2	-2.1	-1.6	-0.9	-0.6	-0.0
Risk taking	0.2	0.2	1.0	-0.4	0.1	0.3	-0.3	-0.1	0.7	-0.7	-0.4	1.0	0.3
Ever had prostate specific antigen (PSA) test	1.2	1.4	3.1	1.5	0.8	-1.4	-0.8	-0.8	1.6	0.5	0.3	1.3	-1.8
Fractured/broken bones in last 5 years	0.6	0.8	3.7	-0.7	-1.0	0.9	-0.1	-0.5	-0.8	-1.9	-0.6	-0.8	0.3
Age started oral contraceptive pill	1.7	2.1	6.2	-1.6	-1.7	0.3	-0.1	-1.0	-1.6	-2.0	-2.5	-1.0	-0.7
Diastolic blood pressure, automated reading	0.5	1.5	9.2	0.5	0.3	-0.1	-0.8	-0.7	-3.0	-1.4	0.3	-1.2	-0.6
Ever depressed for a whole week	0.4	0.5	1.8	0.2	-1.2	0.6	-0.2	-0.4	-1.3	-0.5	-1.1	0.4	-0.0
Unable to work because of sickness or disability	0.4	0.5	2.9	-0.5	0.3	0.1	-0.4	-0.3	1.7	1.0	0.5	-0.8	0.2
Commuting to job workplace: Cycle	0.7	0.8	3.2	1.8	-1.0	-1.1	0.0	-0.2	-1.2	-0.5	-0.2	0.9	-0.7
Myopia	0.7	1.0	3.0	0.5	0.8	-0.2	-1.5	-1.4	1.7	0.2	-0.1	0.8	-1.0
Vascular/heart problems diagnosed by doctor	0.8	2.3	11.3	0.2	2.4	1.6	-0.9	-0.0	3.4	0.9	1.1	0.2	0.4
Cholesterol lowering medication	0.3	0.4	1.8	-0.7	0.2	0.5	0.6	0.4	-0.2	1.3	0.5	0.7	0.2
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	4.7	-1.2	-1.8	0.8	1.1	0.7	-2.2	-1.3	-0.4	-0.9	1.1
Pain experienced in last month	1.0	1.6	6.2	-0.4	2.5	1.0	-1.5	-0.8	0.9	2.2	-0.2	0.3	-0.4
Supplements: Calcium	0.6	0.7	1.9	1.3	-0.7	-0.8	-0.2	-0.8	0.5	0.1	-0.6	0.8	-1.4
Basal cell carcinoma (self-reported)	0.9	1.1	3.1	-1.8	-0.5	1.3	1.2	0.7	-1.4	0.5	0.4	-0.7	0.8
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.1	-1.0	-0.5	0.6	0.5	0.2	-0.9	-0.6	-0.6	-0.8	1.0
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	4.4	-0.5	-0.7	-0.7	-1.3	-1.5	-0.6	-1.6	-2.1	0.5	-1.5
Heart disease (siblings)	3.8	4.7	14.2	-1.3	-1.2	3.8	1.9	1.4	-2.9	0.2	-0.7	-2.9	2.6
Alcohol drinker status: Previous	0.5	0.5	1.4	0.4	1.2	0.0	-1.1	-0.7	0.5	-0.2	-0.8	0.6	-1.0
Pack years of smoking	1.1	1.7	6.4	-2.5	-0.3	-0.7	-1.0	-1.3	0.6	-2.3	-1.1	-0.4	-0.5
Impedance of whole body	0.6	3.3	8.3	1.2	0.2	0.2	-2.9	-2.5	-1.8	-1.9	-2.1	-1.0	-2.0
Leg fat mass (left)	0.3	1.3	3.8	-2.0	-1.8	-0.1	1.3	0.8	0.0	-0.4	-1.5	0.2	0.9
Arm predicted mass (left)	0.5	2.4	14.7	-3.8	-1.0	0.6	1.8	1.4	-0.2	-0.0	-0.4	0.4	1.5