[Hub]/) : Traits : Lung FVC :

chr5:138,933,151-140,784,895

Best TWAS P=1.92e-09 · Best GWAS P=2.98e-07 conditioned to 0.207

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NDUFA2 0.02 0.01 bslmm 343 0.01 7.8e-03 -4.4 5.1 2.8e-07 0.73 0.09 0.55 FALSE
2 CommonMind Brain Pre-frontal Cortex ZMAT2 0.06 0.10 blup 360 0.09 1.4e-11 -4.4 -5.6 2.1e-08 -0.67 0.14 0.83 FALSE
3 GTEx Adipose Visceral Omentum TMCO6 0.06 0.01 enet 7 0.03 1.3e-02 -4.7 -5.4 8.3e-08 -0.47 0.06 0.79 FALSE
4 GTEx Artery Tibial SRA1 0.07 0.02 lasso 10 0.02 7.8e-03 -4.7 -5.3 1.1e-07 -0.44 0.09 0.55 FALSE
5 GTEx Brain Cerebellum TMCO6 0.23 0.18 enet 14 0.22 3.3e-07 -4.4 -5.6 2.3e-08 -0.62 0.07 0.91 FALSE
6 GTEx Breast Mammary Tissue (Male) PFDN1 0.24 0.04 lasso 9 0.09 4.0e-03 -4.8 5.6 1.6e-08 0.37 0.05 0.66 FALSE
7 GTEx Breast Mammary Tissue (Male) TMCO6 0.12 -0.01 lasso 2 -0.01 4.9e-01 -4.7 -5.2 2.3e-07 -0.37 0.03 0.20 FALSE
8 GTEx Cells Transformed fibroblasts TMCO6 0.11 0.11 lasso 6 0.11 1.8e-08 -4.8 -5.4 6.0e-08 -0.54 0.04 0.95 FALSE
9 GTEx Esophagus Mucosa TMCO6 0.04 0.02 lasso 4 0.01 6.1e-02 -4.8 -5.8 5.1e-09 -0.67 0.08 0.69 FALSE
10 GTEx Lung TMCO6 0.06 0.03 lasso 3 0.03 1.1e-03 -4.4 -5.2 2.6e-07 -0.49 0.09 0.86 FALSE
11 GTEx Skin Sun Exposed Lower leg SRA1 0.05 0.04 lasso 3 0.06 1.0e-05 -4.6 -5.4 6.7e-08 -0.51 0.07 0.88 FALSE
12 METSIM Adipose TMCO6 0.10 0.08 lasso 8 0.11 7.0e-16 -4.5 -5.1 2.8e-07 -0.42 0.04 0.95 FALSE
13 ROSMAP Brain Pre-frontal Cortex ZMAT2 0.03 0.02 bslmm 185 0.02 6.5e-04 -4.5 -6.0 1.9e-09 -0.70 0.08 0.87 TRUE
14 YFS Blood APBB3 0.01 0.00 bslmm 318 0.00 2.7e-02 -4.7 6.0 2.3e-09 0.65 0.07 0.60 FALSE
15 The Cancer Genome Atlas Brain Lower Grade Glioma PCDHA13 0.07 0.06 blup 29 0.09 8.6e-11 4.3 5.2 2.4e-07 0.90 0.02 0.95 FALSE
16 The Cancer Genome Atlas Pancreatic Adenocarcinoma NDUFA2 0.10 0.04 blup 43 0.06 1.4e-03 -4.4 5.1 3.1e-07 0.55 0.02 0.75 FALSE