Best TWAS P=2.13e-09 · Best GWAS P=2.59e-09 conditioned to 0.311
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | FAM73A | 0.03 | 0.00 | bslmm | 444 | 0.01 | 4.3e-02 | 1.4 | -5.3 | 9.7e-08 | -0.63 | 0.11 | 0.43 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | USP33 | 0.15 | 0.07 | lasso | 3 | 0.08 | 3.8e-09 | 5.8 | 6.0 | 2.1e-09 | 0.93 | 0.00 | 1.00 | TRUE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | USP33 | 0.04 | 0.01 | blup | 42 | 0.02 | 7.0e-03 | 5.1 | 5.5 | 2.9e-08 | 0.90 | 0.03 | 0.78 | FALSE |