Best TWAS P=5.62e-08 · Best GWAS P=1.41e-06 conditioned to 0.896
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Sigmoid | RP1-199J3.5 | 0.38 | 0.33 | enet | 36 | 0.39 | 7.3e-15 | 4.8 | -5.2 | 1.9e-07 | -0.84 | 0.02 | 0.96 | FALSE |
| 2 | GTEx | Prostate | RP1-199J3.5 | 0.42 | 0.16 | lasso | 8 | 0.21 | 6.4e-06 | 4.8 | -5.4 | 5.6e-08 | -0.88 | 0.03 | 0.93 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | RP1-199J3.5 | 0.18 | 0.22 | enet | 27 | 0.24 | 4.3e-30 | 4.8 | -5.2 | 2.0e-07 | -0.92 | 0.01 | 0.98 | FALSE |