[Hub]/) : Traits : Lung FVC : ← →

chr6:80,120,201-81,763,771

Best TWAS P=1.77e-11 · Best GWAS P=3.01e-10 conditioned to 0.406

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	RP11-250B2.6	0.07	0.04	lasso	4	0.05	4.4e-05	6.1	-6.3	3.1e-10	-0.83	0.03	0.96	FALSE
2	GTEx	Artery Aorta	BCKDHB	0.14	0.14	lasso	1	0.13	9.8e-08	6.0	6.0	2.5e-09	0.83	0.05	0.95	FALSE
3	GTEx	Artery Coronary	BCKDHB	0.29	0.05	lasso	27	0.11	1.7e-04	5.9	5.6	2.6e-08	0.61	0.05	0.88	FALSE
4	GTEx	Artery Tibial	BCKDHB	0.16	0.16	lasso	11	0.15	4.9e-12	5.9	6.1	1.4e-09	0.86	0.05	0.95	FALSE
5	GTEx	Breast Mammary Tissue	RP11-250B2.6	0.12	0.02	enet	9	0.03	1.7e-02	6.1	-5.5	3.2e-08	-0.72	0.03	0.90	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	BCKDHB	0.15	0.11	enet	34	0.07	3.1e-03	6.1	5.5	5.0e-08	0.68	0.04	0.90	FALSE
7	GTEx	Colon Transverse	RP11-250B2.6	0.15	0.16	lasso	2	0.13	9.8e-07	6.1	-6.1	1.0e-09	-0.77	0.02	0.98	FALSE
8	GTEx	Esophagus Mucosa	BCKDHB	0.17	0.16	lasso	6	0.15	3.9e-10	-5.2	5.8	6.5e-09	0.43	0.79	0.21	FALSE
9	GTEx	Esophagus Muscularis	BCKDHB	0.18	0.07	enet	25	0.06	2.4e-04	6.0	6.1	8.9e-10	0.83	0.04	0.96	FALSE
10	GTEx	Lung	BCKDHB	0.09	0.06	enet	10	0.05	1.8e-04	6.0	6.0	2.5e-09	0.83	0.04	0.96	FALSE
11	GTEx	Nerve Tibial	BCKDHB	0.18	0.11	lasso	9	0.10	2.4e-07	5.9	6.3	3.1e-10	0.83	0.04	0.96	FALSE
12	GTEx	Nerve Tibial	RP11-250B2.6	0.13	0.09	enet	10	0.09	8.7e-07	6.1	-6.7	1.8e-11	-0.88	0.02	0.98	TRUE
13	GTEx	Pancreas	BCKDHB	0.14	0.08	enet	6	0.05	3.8e-03	6.3	6.4	1.5e-10	0.97	0.02	0.95	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	RP11-250B2.6	0.08	0.05	lasso	4	0.01	8.1e-02	6.1	-6.0	2.6e-09	-0.73	0.03	0.85	FALSE
15	GTEx	Skin Sun Exposed Lower leg	BCKDHB	0.08	0.05	enet	26	0.05	8.8e-05	-5.2	6.0	1.9e-09	0.50	0.30	0.58	FALSE
16	GTEx	Stomach	RP11-250B2.6	0.13	0.15	lasso	6	0.12	2.5e-06	6.1	-6.2	4.4e-10	-0.77	0.02	0.98	FALSE
17	GTEx	Testis	RP11-250B2.6	0.09	0.05	lasso	6	0.04	6.9e-03	6.1	-6.1	8.4e-10	-0.72	0.04	0.92	FALSE
18	GTEx	Thyroid	BCKDHB	0.17	0.06	lasso	8	0.10	3.4e-08	6.1	5.2	2.0e-07	0.75	0.02	0.98	FALSE
19	GTEx	Thyroid	RP11-250B2.6	0.11	0.10	lasso	2	0.07	3.2e-06	6.1	-6.1	1.1e-09	-0.76	0.02	0.98	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	BCKDHB	0.18	0.13	lasso	6	0.14	2.9e-17	5.9	6.4	1.2e-10	0.89	0.05	0.95	FALSE
21	The Cancer Genome Atlas	Testicular Germ Cell Tumors	BCKDHB	0.19	0.02	blup	137	0.06	2.6e-03	5.9	6.5	1.0e-10	0.67	0.02	0.34	FALSE