Best TWAS P=2.56e-18 · Best GWAS P=5.01e-19 conditioned to 3.89e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CENPW | 0.04 | 0.06 | lasso | 10 | 0.06 | 2.4e-07 | 8.1 | -8.3 | 1.3e-16 | 0.56 | 0.37 | 0.63 | FALSE |
| 2 | GTEx | Heart Atrial Appendage | CENPW | 0.17 | 0.01 | enet | 15 | 0.06 | 1.8e-03 | 8.2 | -5.4 | 5.4e-08 | 0.35 | 0.05 | 0.23 | FALSE |
| 3 | METSIM | Adipose | CENPW | 0.02 | 0.02 | blup | 189 | 0.01 | 8.3e-03 | 8.2 | -7.2 | 6.3e-13 | 0.47 | 0.07 | 0.24 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CENPW | 0.04 | 0.05 | lasso | 5 | 0.05 | 2.6e-06 | 8.1 | -8.6 | 7.5e-18 | 0.63 | 0.34 | 0.65 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CENPW | 0.04 | 0.06 | blup | 35 | 0.05 | 9.2e-07 | 8.2 | -8.7 | 2.6e-18 | 0.67 | 0.37 | 0.63 | TRUE |