Best TWAS P=1.11e-07 · Best GWAS P=6.26e-08 conditioned to 0.114
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | SMPD2 | 0.10 | 0.04 | enet | 11 | 0.03 | 1.5e-02 | -4.6 | -5.3 | 1.5e-07 | -0.05 | 0.03 | 0.96 | TRUE |
| 2 | GTEx | Artery Tibial | RP11-425D10.10 | 0.10 | 0.10 | lasso | 4 | 0.10 | 3.9e-08 | -4.9 | -5.2 | 2.0e-07 | -0.01 | 0.02 | 0.98 | FALSE |
| 3 | YFS | Blood | FOXO3 | 0.03 | 0.01 | lasso | 3 | 0.02 | 3.2e-07 | 4.9 | -5.3 | 1.1e-07 | -0.78 | 0.08 | 0.91 | TRUE |
| 4 | The Cancer Genome Atlas | Esophageal Carcinoma | SMPD2 | 0.12 | 0.09 | blup | 41 | 0.07 | 2.6e-03 | -5.1 | -5.1 | 3.1e-07 | -0.02 | 0.01 | 0.86 | FALSE |