Best TWAS P=1.52e-10 · Best GWAS P=6.92e-11 conditioned to 0.145
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | EPB41L2 | 0.09 | 0.00 | lasso | 4 | 0.00 | 2.9e-01 | 6.5 | 6.4 | 1.5e-10 | 0.94 | 0.03 | 0.84 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | LOC285733 | 0.22 | 0.19 | enet | 9 | 0.19 | 3.9e-11 | 5.6 | 5.4 | 6.4e-08 | 0.76 | 0.02 | 0.98 | FALSE |
3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | LOC285733 | 0.22 | 0.10 | blup | 67 | 0.08 | 2.6e-04 | 5.4 | 5.9 | 3.5e-09 | 0.77 | 0.02 | 0.95 | FALSE |