[Hub]/) : Traits : Lung FVC : ← →

chr6:133,575,570-136,516,257

Best TWAS P=1.46e-13 · Best GWAS P=1.79e-14 conditioned to 0.0991

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Tibial	AHI1	0.11	0.03	enet	16	0.09	1.8e-07	-6.0	5.7	1.2e-08	-0.78	0.01	0.98	FALSE
2	GTEx	Brain Cortex	AHI1	0.51	0.27	lasso	6	0.37	3.3e-11	-5.0	5.3	1.1e-07	-0.71	0.06	0.94	FALSE
3	GTEx	Brain Cortex	RP3-388E23.2	0.28	0.16	enet	13	0.19	5.8e-06	-2.5	5.2	2.1e-07	-0.72	0.05	0.90	FALSE
4	GTEx	Brain Hippocampus	AHI1	0.28	0.10	lasso	5	0.05	2.9e-02	-5.0	5.2	2.5e-07	-0.69	0.08	0.39	FALSE
5	GTEx	Brain Putamen basal ganglia	AHI1	0.30	0.11	enet	36	0.12	1.0e-03	-6.9	5.3	1.4e-07	-0.69	0.05	0.80	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	AHI1	0.38	0.24	enet	19	0.23	5.4e-08	-6.3	7.0	1.9e-12	-0.81	0.47	0.50	FALSE
7	GTEx	Cells EBV-transformed lymphocytes	RP3-388E23.2	0.26	0.05	lasso	6	0.02	7.1e-02	-6.6	6.3	2.5e-10	-0.84	0.18	0.27	FALSE
8	GTEx	Cells Transformed fibroblasts	AHI1	0.44	0.21	enet	22	0.32	4.4e-24	-6.9	6.2	5.4e-10	-0.75	0.44	0.56	FALSE
9	GTEx	Esophagus Mucosa	AHI1	0.30	0.24	lasso	8	0.32	4.6e-22	-6.6	6.1	9.2e-10	-0.74	0.82	0.18	FALSE
10	GTEx	Lung	TBPL1	0.15	0.00	enet	19	0.00	4.0e-01	4.9	6.1	1.2e-09	-0.06	0.01	0.70	TRUE
11	GTEx	Skin Not Sun Exposed Suprapubic	AHI1	0.41	0.31	lasso	7	0.40	9.1e-24	-6.6	6.0	2.1e-09	-0.77	0.81	0.19	FALSE
12	GTEx	Skin Sun Exposed Lower leg	AHI1	0.33	0.22	enet	14	0.34	1.0e-28	-2.5	5.3	1.1e-07	-0.66	0.99	0.01	FALSE
13	GTEx	Small Intestine Terminal Ileum	AHI1	0.51	0.01	enet	19	0.06	2.0e-02	-6.6	5.8	5.0e-09	-0.67	0.06	0.22	FALSE
14	GTEx	Spleen	AHI1	0.31	0.21	lasso	3	0.38	8.6e-11	-3.4	5.4	6.8e-08	-0.68	0.18	0.53	FALSE
15	GTEx	Testis	AHI1	0.37	0.32	enet	25	0.37	3.5e-17	-6.6	6.3	3.2e-10	-0.74	0.79	0.21	FALSE
16	METSIM	Adipose	AHI1	0.25	0.22	lasso	7	0.28	1.1e-42	-6.3	6.5	6.7e-11	-0.81	0.30	0.70	FALSE
17	NTR	Blood	AHI1	0.11	0.14	lasso	6	0.15	3.2e-47	-6.6	6.8	1.0e-11	-0.85	0.70	0.30	FALSE
18	YFS	Blood	AHI1	0.24	0.30	bslmm	414	0.33	1.4e-110	-6.6	6.3	2.9e-10	-0.77	0.84	0.16	FALSE
19	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SLC2A12	0.07	0.06	enet	7	0.05	6.4e-05	-4.7	-5.6	1.8e-08	-0.01	0.01	0.95	TRUE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	AHI1	0.06	0.02	lasso	7	0.02	1.3e-04	-6.6	5.7	9.1e-09	-0.73	0.00	1.00	FALSE
21	The Cancer Genome Atlas	Breast Invasive Carcinoma	C6orf217	0.02	0.02	blup	80	0.02	1.2e-05	-6.8	7.4	1.5e-13	-0.88	0.01	0.99	TRUE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	TCF21	0.04	0.01	blup	40	0.02	9.9e-06	-4.4	5.8	5.6e-09	-0.05	0.01	0.92	TRUE
23	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	AHI1	0.06	0.08	blup	73	0.06	1.1e-03	-6.6	5.3	1.3e-07	-0.67	0.00	0.98	FALSE
24	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	AHI1	0.18	0.19	lasso	4	0.18	6.4e-20	-6.6	6.4	1.2e-10	-0.82	0.00	1.00	FALSE
25	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC2A12	0.08	0.03	enet	8	0.04	3.5e-05	3.3	-5.4	5.4e-08	-0.01	0.01	0.96	FALSE
26	The Cancer Genome Atlas	Brain Lower Grade Glioma	AHI1	0.03	0.02	enet	7	0.01	8.1e-03	-6.6	6.6	3.7e-11	-0.79	0.00	0.97	FALSE
27	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	AHI1	0.13	0.16	lasso	3	0.16	1.2e-17	-6.6	6.4	1.6e-10	-0.80	0.00	1.00	FALSE
28	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C6orf217	0.04	0.03	blup	81	0.01	1.7e-02	-6.3	7.0	2.1e-12	-0.84	0.01	0.95	FALSE
29	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	AHI1	0.05	0.05	lasso	1	0.04	1.5e-03	-6.3	6.3	2.9e-10	-0.82	0.00	0.96	FALSE
30	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf217	0.06	0.06	enet	9	0.07	1.6e-05	-6.9	7.0	2.3e-12	-0.91	0.01	0.99	FALSE
31	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C6orf217	0.10	0.00	blup	82	0.04	6.8e-03	-6.8	6.9	5.2e-12	-0.83	0.02	0.53	FALSE
32	The Cancer Genome Atlas	Prostate Adenocarcinoma	C6orf217	0.07	0.07	blup	81	0.09	4.3e-10	-5.1	6.1	1.4e-09	-0.62	0.21	0.79	FALSE
33	The Cancer Genome Atlas	Stomach Adenocarcinoma	C6orf217	0.06	0.02	lasso	3	0.02	7.7e-03	-7.7	6.7	2.1e-11	-0.92	0.00	0.88	FALSE
34	The Cancer Genome Atlas	Testicular Germ Cell Tumors	AHI1	0.36	0.30	lasso	3	0.29	1.0e-10	-6.3	6.2	7.3e-10	-0.81	0.00	1.00	FALSE
35	The Cancer Genome Atlas	Thyroid Carcinoma	C6orf217	0.30	0.24	enet	16	0.26	1.5e-25	-4.3	5.2	2.3e-07	-0.64	1.00	0.00	FALSE