Best TWAS P=5.82e-18 · Best GWAS P=3.49e-53 conditioned to 8.37e-39
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | AC004985.12 | 0.13 | -0.01 | enet | 57 | 0.00 | 3.3e-01 | -12.80 | 5.9 | 3.4e-09 | 0.20 | 0.03 | 0.09 | TRUE |
| 2 | GTEx | Vagina | POLM | 0.47 | -0.01 | enet | 31 | 0.08 | 6.8e-03 | 0.28 | -5.6 | 1.9e-08 | -0.39 | 0.04 | 0.26 | TRUE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | GCK | 0.05 | 0.00 | blup | 58 | 0.04 | 4.1e-04 | 12.70 | 8.6 | 5.8e-18 | 0.01 | 0.03 | 0.03 | TRUE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GCK | 0.05 | 0.02 | enet | 9 | 0.06 | 1.1e-11 | -2.29 | 6.6 | 3.4e-11 | -0.01 | 0.98 | 0.00 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | YKT6 | 0.09 | 0.00 | enet | 7 | 0.02 | 2.4e-03 | 0.12 | 5.5 | 2.9e-08 | 0.03 | 0.03 | 0.03 | TRUE |