[Hub]/) : Traits : Fasting Glucose : ← →

chr11:46,570,859-48,028,343

Best TWAS P=3.99e-12 · Best GWAS P=1.27e-12 conditioned to 0.218

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MADD 0.32 0.17 bslmm 315 0.18 1.4e-21 -6.1 6.0 2.7e-09 -0.51 0.48 0.52 FALSE
2 GTEx Artery Tibial MADD 0.09 0.00 enet 13 0.02 1.1e-02 -6.3 6.3 2.7e-10 -0.73 0.04 0.92 FALSE
3 GTEx Brain Hypothalamus NR1H3 0.25 0.18 lasso 5 0.10 2.7e-03 5.4 5.5 2.9e-08 -0.42 0.13 0.17 FALSE
4 GTEx Cells EBV-transformed lymphocytes ACP2 0.17 0.03 lasso 6 0.03 4.2e-02 5.2 -6.5 1.1e-10 0.67 0.04 0.88 FALSE
5 GTEx Esophagus Mucosa MADD 0.27 0.04 enet 18 0.12 4.1e-08 -4.6 5.4 6.8e-08 -0.65 0.00 0.99 FALSE
6 GTEx Esophagus Muscularis MADD 0.13 0.07 enet 8 0.11 2.0e-07 -6.1 6.2 5.6e-10 -0.80 0.00 1.00 FALSE
7 GTEx Lung ACP2 0.04 0.03 lasso 2 0.04 4.3e-04 5.2 -5.2 1.6e-07 0.38 0.48 0.14 FALSE
8 GTEx Pituitary MADD 0.42 0.32 lasso 6 0.39 8.9e-11 -7.1 6.4 2.0e-10 -0.89 0.00 1.00 FALSE
9 GTEx Testis NR1H3 0.10 0.10 lasso 6 0.08 2.9e-04 5.0 -5.2 2.3e-07 0.37 0.60 0.04 FALSE
10 METSIM Adipose NR1H3 0.03 0.03 lasso 6 0.04 4.7e-06 -6.3 6.9 4.0e-12 -0.85 0.02 0.98 TRUE
11 ROSMAP Brain Pre-frontal Cortex NR1H3 0.06 0.01 blup 302 0.04 1.5e-05 4.2 5.5 4.3e-08 -0.50 0.12 0.86 FALSE
12 ROSMAP Brain Pre-frontal Cortex MADD 0.33 0.16 enet 23 0.23 1.9e-29 -6.1 6.7 1.8e-11 -0.56 0.48 0.52 TRUE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ACP2 0.03 0.03 blup 44 0.04 3.5e-05 5.0 -5.2 2.2e-07 0.43 0.77 0.03 FALSE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DDB2 0.02 0.03 lasso 1 0.02 1.0e-03 5.2 5.2 1.5e-07 -0.37 0.15 0.08 FALSE