Best TWAS P=2.03e-54 · Best GWAS P=2.64e-99 conditioned to 9.18e-49
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NOSTRIN | 0.14 | 0.13 | lasso | 4 | 0.12 | 1.9e-14 | -7.6 | 5.5 | 3.9e-08 | -0.40 | 1.00 | 0.00 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | NOSTRIN | 0.08 | 0.01 | blup | 526 | 0.02 | 5.9e-04 | -4.2 | 6.6 | 5.5e-11 | -0.39 | 0.40 | 0.50 | TRUE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | G6PC2 | 0.32 | 0.07 | blup | 29 | 0.06 | 3.8e-04 | -3.5 | -13.6 | 6.7e-42 | 0.56 | 0.06 | 0.39 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | G6PC2 | 0.47 | 0.23 | enet | 8 | 0.28 | 4.4e-32 | -3.5 | -10.6 | 2.3e-26 | 0.52 | 1.00 | 0.00 | TRUE |
| 5 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | G6PC2 | 0.56 | 0.13 | blup | 29 | 0.16 | 2.1e-09 | -3.5 | -15.5 | 2.0e-54 | 0.49 | 0.82 | 0.10 | TRUE |
| 6 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | SPC25 | 0.21 | 0.01 | enet | 4 | 0.08 | 2.3e-04 | 4.0 | 6.3 | 3.7e-10 | -0.05 | 0.01 | 0.06 | TRUE |
| 7 | The Cancer Genome Atlas | Stomach Adenocarcinoma | G6PC2 | 0.22 | 0.01 | enet | 4 | 0.08 | 3.1e-06 | -3.5 | -13.3 | 2.2e-40 | 0.60 | 0.11 | 0.36 | FALSE |