[Hub]/) : Traits : Heel T-Score : ← →

chr5:71,490,962-73,083,183

Best TWAS P=4.25e-24 · Best GWAS P=6.26e-18 conditioned to 0.011

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	FCHO2	0.09	0.09	lasso	6	0.10	1.1e-08	5.1	5.5	2.8e-08	-0.03	1.00	0.00	FALSE
2	GTEx	Adipose Visceral Omentum	FCHO2	0.27	0.10	lasso	5	0.06	6.2e-04	6.7	6.2	4.3e-10	-0.01	0.57	0.04	FALSE
3	GTEx	Adrenal Gland	FCHO2	0.11	0.03	lasso	3	0.01	1.2e-01	6.7	6.5	9.2e-11	-0.05	0.18	0.04	FALSE
4	GTEx	Artery Aorta	FCHO2	0.07	0.04	lasso	2	0.03	5.2e-03	6.5	6.4	1.5e-10	-0.06	0.25	0.04	FALSE
5	GTEx	Artery Tibial	FCHO2	0.14	0.03	enet	59	0.02	5.9e-03	3.0	7.5	4.2e-14	0.01	0.44	0.04	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	FCHO2	0.28	0.15	enet	21	0.05	8.7e-03	6.7	5.4	5.3e-08	-0.06	0.23	0.06	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	FCHO2	0.16	-0.01	enet	24	-0.01	7.5e-01	4.4	10.1	4.3e-24	0.45	0.05	0.40	TRUE
8	GTEx	Esophagus Mucosa	FCHO2	0.15	0.07	lasso	2	0.09	1.1e-06	6.5	-6.5	9.0e-11	0.06	0.98	0.00	FALSE
9	GTEx	Lung	FCHO2	0.20	0.08	enet	61	0.07	5.6e-06	-6.4	5.9	2.9e-09	-0.04	0.61	0.01	FALSE
10	GTEx	Nerve Tibial	FCHO2	0.10	0.08	enet	17	0.05	3.4e-04	6.7	7.4	1.6e-13	-0.09	0.88	0.01	FALSE
11	GTEx	Pancreas	FCHO2	0.11	0.04	enet	7	0.03	1.8e-02	2.7	5.2	1.7e-07	-0.08	0.26	0.04	FALSE
12	GTEx	Skin Sun Exposed Lower leg	FCHO2	0.06	0.03	enet	20	0.03	2.6e-03	6.7	6.8	9.4e-12	-0.06	0.31	0.03	FALSE
13	METSIM	Adipose	FCHO2	0.06	0.08	lasso	5	0.08	1.9e-11	6.5	6.7	2.8e-11	-0.07	1.00	0.00	FALSE
14	NTR	Blood	FCHO2	0.04	0.03	lasso	4	0.03	2.4e-11	6.5	6.2	4.3e-10	-0.08	1.00	0.00	FALSE
15	YFS	Blood	FCHO2	0.23	0.24	lasso	6	0.29	2.8e-97	6.5	6.3	2.9e-10	-0.08	1.00	0.00	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	BTF3	0.02	0.02	lasso	3	0.02	2.5e-04	5.4	5.4	7.7e-08	0.32	0.00	0.97	TRUE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	FCHO2	0.05	0.04	blup	84	0.04	1.9e-09	6.6	6.0	2.5e-09	-0.01	0.00	1.00	FALSE
18	The Cancer Genome Atlas	Colon Adenocarcinoma	FCHO2	0.10	0.08	blup	84	0.08	3.6e-05	6.6	6.4	1.9e-10	-0.06	0.00	0.99	FALSE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ZNF366	0.03	0.01	blup	70	0.01	9.6e-03	5.6	-5.6	2.3e-08	-0.05	0.04	0.22	TRUE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	FCHO2	0.05	0.04	lasso	4	0.03	9.8e-05	6.6	6.6	4.2e-11	-0.05	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Rectum Adenocarcinoma	FCHO2	0.32	0.16	blup	84	0.21	1.0e-05	4.3	5.9	2.8e-09	-0.05	0.06	0.89	FALSE
22	The Cancer Genome Atlas	Soft Tissue Sarcoma	FCHO2	0.06	0.04	blup	84	0.05	8.9e-04	4.3	5.9	3.6e-09	-0.04	0.05	0.89	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	FCHO2	0.05	0.03	blup	84	0.01	1.2e-02	5.1	6.0	2.0e-09	-0.05	0.02	0.82	FALSE