Best TWAS P=8.63e-09 · Best GWAS P=1.53e-09 conditioned to 0.259
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | BHMT2 | 0.10 | 0.03 | blup | 404 | 0.06 | 8.9e-08 | 1.8 | -5.6 | 2.2e-08 | -0.18 | 0.99 | 0.00 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | ARSB | 0.09 | 0.03 | lasso | 2 | 0.03 | 2.0e-04 | -3.5 | 5.8 | 8.6e-09 | 0.75 | 0.01 | 0.96 | TRUE |