Best TWAS P=5.94e-12 · Best GWAS P=2.26e-22 conditioned to 1.27e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | CTC-228N24.3 | 0.24 | 0.15 | enet | 16 | 0.20 | 3.4e-16 | -4.7 | 5.4 | 5.4e-08 | -0.01 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Adrenal Gland | CTC-228N24.3 | 0.34 | 0.10 | lasso | 9 | 0.09 | 4.2e-04 | -8.1 | 6.9 | 5.9e-12 | -0.05 | 0.66 | 0.02 | TRUE |
| 3 | GTEx | Spleen | CTC-228N24.3 | 0.26 | 0.03 | enet | 15 | 0.05 | 1.8e-02 | 1.4 | 5.2 | 2.1e-07 | -0.04 | 0.07 | 0.08 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | FBN2 | 0.08 | 0.10 | enet | 16 | 0.09 | 5.4e-06 | -4.6 | -5.5 | 3.5e-08 | 0.47 | 0.78 | 0.13 | TRUE |