[Hub]/) : Traits : Heel T-Score : ← →

chr5:120,950,799-123,649,166

Best TWAS P=5.37e-28 · Best GWAS P=2.27e-33 conditioned to 0.00189

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CSNK1G3 0.16 0.16 enet 9 0.15 3.0e-18 6.9 -7.1 1.1e-12 0.62 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous CEP120 0.12 0.08 lasso 3 0.05 5.5e-05 -10.6 -11.0 5.4e-28 0.85 0.13 0.85 TRUE
3 GTEx Artery Aorta KRT8P33 0.10 0.04 lasso 6 0.05 9.1e-04 3.3 -7.5 5.1e-14 0.55 0.09 0.65 FALSE
4 GTEx Brain Cerebellum SNCAIP 0.28 -0.01 enet 31 0.03 5.6e-02 -2.5 5.1 2.8e-07 -0.02 0.02 0.04 TRUE
5 GTEx Breast Mammary Tissue (Female) PPIC 0.02 0.12 lasso 1 0.09 9.5e-04 -5.9 5.9 3.5e-09 -0.24 0.04 0.06 TRUE
6 GTEx Cells EBV-transformed lymphocytes KRT8P33 0.16 -0.01 lasso 8 0.01 2.1e-01 -10.6 -10.4 2.3e-25 0.74 0.06 0.48 FALSE
7 GTEx Esophagus Mucosa CSNK1G3 0.14 0.05 lasso 3 0.07 2.0e-05 -8.4 -7.0 2.8e-12 0.68 0.47 0.47 FALSE
8 ROSMAP Brain Pre-frontal Cortex PPIC 0.08 0.03 bslmm 433 0.04 2.3e-06 -2.5 7.2 8.2e-13 -0.32 0.76 0.05 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma CSNK1G3 0.04 0.02 enet 8 0.02 1.2e-04 -8.4 -5.2 2.0e-07 0.47 0.03 0.07 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CSNK1G3 0.21 0.01 blup 75 0.04 1.6e-05 6.4 5.3 1.3e-07 -0.29 0.15 0.04 TRUE
11 The Cancer Genome Atlas Lung Adenocarcinoma CSNK1G3 0.06 0.05 lasso 2 0.04 2.0e-05 -8.4 -8.4 5.6e-17 0.79 0.25 0.64 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma CEP120 0.10 0.14 blup 70 0.14 2.6e-14 7.6 -8.8 1.4e-18 0.52 1.00 0.00 TRUE
13 The Cancer Genome Atlas Prostate Adenocarcinoma CSNK1G3 0.06 0.04 enet 10 0.05 2.3e-06 -12.0 -10.5 9.9e-26 0.86 0.00 0.99 FALSE