Best TWAS P=7.32e-10 · Best GWAS P=2.37e-15 conditioned to 4.63e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RP11-61I13.3 | 0.08 | 0.00 | enet | 15 | 0.00 | 1.2e-01 | 3.2 | -5.5 | 4.7e-08 | -0.64 | 0.11 | 0.62 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | MOCS1 | 0.10 | 0.01 | enet | 22 | 0.08 | 6.4e-10 | -1.8 | 5.3 | 1.3e-07 | 0.55 | 0.30 | 0.70 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | MOCS1 | 0.11 | 0.03 | blup | 88 | 0.04 | 2.1e-03 | 7.6 | 6.2 | 7.3e-10 | 0.71 | 0.02 | 0.90 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | MOCS1 | 0.14 | 0.11 | blup | 88 | 0.16 | 2.8e-15 | -4.4 | 5.5 | 4.8e-08 | 0.72 | 0.99 | 0.01 | FALSE |