Best TWAS P=1.14e-07 · Best GWAS P=4.76e-09 conditioned to 0.0108
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Mucosa | FOXP4 | 0.21 | 0.15 | lasso | 5 | 0.14 | 6.4e-10 | -5.2 | 5.3 | 1.4e-07 | -0.72 | 0.06 | 0.94 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FOXP4 | 0.04 | 0.02 | blup | 71 | 0.02 | 4.2e-03 | -5.9 | 5.3 | 1.1e-07 | -0.86 | 0.00 | 0.93 | TRUE |