Best TWAS P=5.77e-39 · Best GWAS P=2.85e-44 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | MTO1 | 0.13 | 0.09 | enet | 16 | 0.11 | 1.2e-06 | -4.3 | 6.9 | 4.2e-12 | -0.27 | 0.48 | 0.46 | TRUE |
| 2 | GTEx | Artery Aorta | CD109 | 0.32 | 0.22 | enet | 17 | 0.23 | 5.9e-13 | 12.3 | -12.8 | 2.8e-37 | 0.69 | 0.66 | 0.34 | TRUE |
| 3 | GTEx | Pancreas | CD109 | 0.18 | 0.07 | lasso | 5 | 0.07 | 5.0e-04 | -13.9 | -13.1 | 5.8e-39 | 0.97 | 0.01 | 0.96 | TRUE |
| 4 | GTEx | Spleen | CD109 | 0.27 | 0.02 | lasso | 4 | 0.02 | 7.6e-02 | 13.4 | -10.9 | 6.9e-28 | 0.82 | 0.02 | 0.63 | FALSE |
| 5 | GTEx | Testis | EEF1A1 | 0.10 | 0.00 | lasso | 6 | -0.01 | 6.4e-01 | 4.4 | -6.0 | 2.3e-09 | 0.41 | 0.07 | 0.14 | TRUE |