Best TWAS P=1.52e-23 · Best GWAS P=2.13e-53 conditioned to 3.32e-15
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | MEOX2 | 0.11 | 0.08 | lasso | 6 | 0.08 | 4.4e-10 | 9.0 | -7.6 | 3.5e-14 | 0.60 | 0.88 | 0.12 | TRUE |
| 2 | GTEx | Artery Aorta | MEOX2 | 0.13 | 0.01 | enet | 19 | 0.04 | 3.4e-03 | 3.0 | -7.0 | 3.1e-12 | 0.03 | 0.15 | 0.04 | FALSE |
| 3 | GTEx | Artery Tibial | MEOX2 | 0.11 | 0.00 | enet | 60 | 0.03 | 1.6e-03 | -13.1 | -10.0 | 1.5e-23 | 0.42 | 0.05 | 0.56 | TRUE |
| 4 | GTEx | Skin Sun Exposed Lower leg | RP11-196O16.1 | 0.10 | 0.00 | enet | 11 | 0.00 | 1.4e-01 | 1.2 | 6.3 | 2.9e-10 | -0.27 | 0.07 | 0.04 | TRUE |