[Hub]/) : Traits : Heel T-Score : ← →

chr7:1,787,236-3,581,391

Best TWAS P=1.28e-17 · Best GWAS P=2.12e-17 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	GNA12	0.11	0.08	lasso	4	0.07	1.3e-06	7.1	6.5	5.8e-11	0.72	0.58	0.42	FALSE
2	GTEx	Artery Tibial	GNA12	0.24	0.13	enet	20	0.22	3.5e-17	8.2	7.1	1.5e-12	0.86	0.01	0.99	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	GNA12	0.46	0.51	lasso	5	0.50	7.9e-19	7.9	8.0	1.7e-15	0.88	0.24	0.76	FALSE
4	GTEx	Cells Transformed fibroblasts	GNA12	0.21	0.11	lasso	11	0.15	1.7e-11	8.1	8.4	2.8e-17	0.87	0.01	0.99	FALSE
5	GTEx	Colon Sigmoid	GNA12	0.14	0.05	lasso	3	0.03	3.6e-02	7.2	7.7	1.3e-14	0.83	0.05	0.84	FALSE
6	GTEx	Colon Transverse	LFNG	0.25	0.20	lasso	3	0.17	1.1e-08	6.6	6.7	2.6e-11	0.03	0.99	0.00	TRUE
7	GTEx	Colon Transverse	GNA12	0.19	0.08	lasso	4	0.10	2.3e-05	-3.8	5.2	2.5e-07	0.63	0.18	0.81	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	GNA12	0.20	0.12	lasso	6	0.12	3.4e-05	7.1	7.7	1.0e-14	0.82	0.04	0.94	FALSE
9	GTEx	Esophagus Mucosa	GNA12	0.16	0.13	lasso	3	0.13	3.0e-09	8.5	8.6	1.3e-17	0.96	0.00	1.00	TRUE
10	GTEx	Esophagus Muscularis	GNA12	0.32	0.31	lasso	3	0.34	2.1e-21	8.2	8.0	8.9e-16	0.91	0.03	0.97	FALSE
11	GTEx	Esophagus Muscularis	AC004840.9	0.19	0.07	enet	34	0.10	1.2e-06	-2.2	-5.7	1.5e-08	-0.20	0.47	0.06	FALSE
12	GTEx	Lung	GNA12	0.16	0.08	enet	21	0.12	1.2e-09	8.4	8.4	5.1e-17	0.79	0.00	1.00	FALSE
13	GTEx	Nerve Tibial	GNA12	0.31	0.34	lasso	7	0.36	9.6e-27	7.1	8.1	7.0e-16	0.84	0.96	0.04	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	GNA12	0.10	0.15	lasso	3	0.12	4.2e-07	-7.9	8.2	2.8e-16	0.57	0.18	0.81	FALSE
15	GTEx	Skin Sun Exposed Lower leg	GNA12	0.17	0.16	lasso	3	0.18	1.3e-14	6.8	7.9	3.1e-15	0.84	0.19	0.81	FALSE
16	GTEx	Small Intestine Terminal Ileum	GNA12	0.34	0.20	lasso	5	0.16	2.4e-04	6.8	7.4	1.5e-13	0.74	0.08	0.74	FALSE
17	GTEx	Stomach	GNA12	0.18	0.16	lasso	2	0.13	6.6e-07	7.2	7.0	3.3e-12	0.71	0.55	0.44	FALSE
18	GTEx	Whole Blood	GNA12	0.09	0.01	enet	4	0.00	3.3e-01	7.9	8.0	1.5e-15	0.88	0.03	0.89	FALSE
19	METSIM	Adipose	GNA12	0.07	0.05	lasso	3	0.05	3.3e-08	6.8	7.0	2.0e-12	0.74	0.44	0.56	FALSE
20	NTR	Blood	GNA12	0.07	0.03	bslmm	597	0.06	1.3e-17	7.8	6.0	2.7e-09	0.57	0.30	0.70	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	AMZ1	0.09	0.05	lasso	6	0.04	2.4e-06	8.2	-7.0	2.9e-12	-0.88	0.02	0.98	FALSE
22	The Cancer Genome Atlas	Colon Adenocarcinoma	GNA12	0.09	0.00	blup	103	0.03	9.3e-03	7.1	5.2	2.5e-07	0.49	0.04	0.12	FALSE
23	The Cancer Genome Atlas	Esophageal Carcinoma	AMZ1	0.18	0.05	blup	69	0.05	1.4e-02	-5.6	7.0	2.2e-12	0.74	0.01	0.60	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GNA12	0.03	0.04	lasso	1	0.04	3.0e-05	7.1	7.1	1.5e-12	0.68	0.10	0.69	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	AMZ1	0.04	0.04	lasso	3	0.02	1.3e-03	-5.6	-6.4	1.9e-10	-0.66	0.02	0.94	FALSE
26	The Cancer Genome Atlas	Lung Adenocarcinoma	GNA12	0.03	0.01	enet	7	0.02	1.5e-03	-2.5	5.9	3.5e-09	0.75	0.05	0.78	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	AMZ1	0.08	0.01	blup	71	0.05	1.3e-05	7.1	-5.7	1.4e-08	-0.67	0.03	0.86	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	AMZ1	0.32	0.04	enet	19	0.20	3.3e-19	7.8	-6.3	3.6e-10	-0.61	0.09	0.91	FALSE