Best TWAS P=1.11e-10 · Best GWAS P=5.37e-19 conditioned to 9e-19
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Nucleus accumbens basal ganglia | CTA-293F17.1 | 0.32 | 0.26 | lasso | 5 | 0.27 | 7.4e-08 | -5.4 | 5.5 | 4.6e-08 | -0.03 | 0.24 | 0.05 | TRUE |
| 2 | GTEx | Nerve Tibial | TWIST1 | 0.15 | 0.11 | lasso | 6 | 0.17 | 5.7e-12 | 1.6 | 6.5 | 1.1e-10 | 0.02 | 0.09 | 0.91 | TRUE |
| 3 | GTEx | Testis | SNX13 | 0.21 | 0.14 | enet | 15 | 0.13 | 2.0e-06 | -4.8 | 5.2 | 1.8e-07 | -0.01 | 0.14 | 0.86 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | SNX13 | 0.15 | 0.16 | lasso | 3 | 0.18 | 1.7e-10 | 5.5 | -5.5 | 3.0e-08 | 0.00 | 0.01 | 0.99 | TRUE |