TWAS hub - MEOX2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1050	0.0280	5.6e-07	0.078	0.066	0.060	0.073	0.081	1.0e-09	1.7e-08	8.0e-08	3.5e-09	4.4e-10
2	GTEx	Artery Aorta	0.1280	0.0520	5.1e-03	0.012	NA	0.038	NA	0.011	7.0e-02	NA	3.4e-03	NA	7.9e-02
3	GTEx	Artery Tibial	0.1132	0.0422	9.2e-04	0.003	NA	0.031	NA	0.005	1.9e-01	NA	1.6e-03	NA	1.3e-01
4	GTEx	Brain Putamen basal ganglia	0.2670	0.1140	9.1e-03	-0.009	NA	-0.012	NA	-0.011	6.1e-01	NA	7.8e-01	NA	7.1e-01
5	ROSMAP	Brain Pre-frontal Cortex	0.0915	0.0283	1.5e-05	0.008	0.052	0.034	0.049	0.035	2.6e-02	2.7e-07	2.6e-05	5.4e-07	2.1e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
Heel T-Score	5.7	45.1	100.0	-7.6	-7.0	-10.0	-1.6	-4.1
Heel bone mineral density (BMD) T-score, automated (left)	5.3	12.1	35.0	-3.5	-3.5	-5.9	0.6	-1.0
Heel bone mineral density (BMD) T-score, automated (right)	4.7	10.8	26.0	-3.3	-3.9	-5.1	-1.2	-0.9
Hand grip strength (right)	3.7	10.0	18.7	4.3	2.2	3.2	-0.2	4.1
Hand grip strength (left)	3.3	8.6	13.0	3.2	2.8	3.5	-0.2	3.6
Exposure to tobacco smoke outside home	3.3	4.4	14.3	1.6	-2.1	-0.9	0.1	3.8
Triglycerides	3.2	5.3	12.1	1.5	-3.5	-1.4	-1.8	2.7
Hearing aid user	3.2	3.7	9.9	3.1	-0.8	0.2	-1.6	2.2
Medication for cholesterol	3.0	4.5	11.6	-2.5	0.8	-1.6	1.2	-3.4
Type 2 Diabetes (T2D) (2018)	2.9	5.5	7.2	1.9	-2.4	-2.0	-2.6	2.7
Medication: Ramipril	2.8	3.6	9.0	3.0	0.2	1.0	-2.0	2.1
Gout (self-reported)	2.8	3.8	7.0	-0.5	2.6	2.6	0.4	-2.2
Medication: Allopurinol	2.8	3.8	7.6	-0.6	2.3	2.8	0.1	-2.3
Guilty feelings	2.7	4.1	14.1	1.2	-1.5	-1.3	-0.9	3.8
Cholesterol lowering medication	2.7	3.9	12.7	1.2	-1.5	-0.4	-1.7	3.6
Eye problems/disorders: Diabetes related eye disease	2.6	2.8	8.8	0.8	-1.4	-1.0	-1.3	3.0
Chronic bronchitis/emphysema (mother)	2.5	2.9	6.3	2.3	1.3	-0.3	-0.9	2.5
Diabetes diagnosed by doctor	2.5	4.1	10.7	2.4	-1.2	-1.0	-1.3	3.3
Loud music exposure frequency	2.3	2.5	4.1	1.8	0.3	1.4	-1.9	2.0
Type 2 Diabetes (T2D) (2012)	2.2	2.5	4.5	1.0	-2.0	-1.0	-1.5	2.1
Other serious medical condition/disability diagnosed by doctor	2.2	2.8	6.3	1.3	-2.4	-0.3	0.2	2.5
Diverticular disease/diverticulitis (self-reported)	2.2	2.6	6.4	-0.5	-2.5	-2.2	-1.0	0.7
Pulse wave peak to peak time	2.2	2.6	4.8	1.6	0.2	-2.2	-1.6	1.7
HDL Cholesterol	2.1	3.5	6.7	0.4	2.6	1.0	2.0	-2.4
Hearing difficulty/problems: Yes	2.1	3.3	7.1	2.0	-1.4	-0.6	-2.7	1.7
Diabetes (mother)	2.1	2.7	6.8	-2.6	-1.1	-2.2	-0.9	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	2.1	3.2	12.6	1.3	-0.9	0.2	-1.0	3.5
Forced expiratory volume in 1-second (FEV1), predicted	2.0	4.1	9.2	3.0	0.4	2.6	-0.7	2.0
Back pain experienced in last month	2.0	2.9	8.5	1.3	-1.4	-0.0	-1.6	2.9
Bilateral oophorectomy (both ovaries removed)	1.9	2.1	6.7	-0.9	1.6	2.6	-0.7	-0.5
Pulse wave Arterial Stiffness index	1.9	2.2	5.2	-1.1	-0.4	2.3	1.6	-1.4
Exposure to tobacco smoke at home	1.9	2.1	6.1	2.5	0.7	1.8	0.9	0.0
Average weekly beer plus cider intake	1.9	2.7	8.0	1.4	1.9	2.8	0.3	0.3
Lung FVC	1.8	9.3	17.6	-4.2	-1.8	-2.6	4.1	-1.2
Supplements: Zinc	1.8	2.0	4.8	-2.1	0.0	-0.9	0.3	-2.2
Hayfever/allergic rhinitis (self-reported)	1.8	2.4	4.7	-1.9	1.1	-0.6	1.4	-2.2
Depression (Nagel 2018)	1.7	2.5	3.4	1.4	-1.1	1.9	-1.8	1.7
Ovarian Cancer	1.7	2.3	6.2	1.1	-0.4	-0.7	-1.8	2.5
HbA1C	1.7	1.8	6.1	1.5	0.3	0.6	0.7	2.5
Severe depression (siblings)	1.7	1.9	5.6	0.9	-1.4	-1.2	-0.1	2.4
Alcohol intake versus 10 years previously	1.7	2.6	6.0	0.3	2.5	2.3	0.0	-1.3
High blood pressure (siblings)	1.7	2.4	7.1	-0.6	1.4	2.7	0.1	-1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.7	2.0	2.7	1.6	0.5	1.6	-1.4	1.5
Leg pain on walking	1.7	2.2	5.3	-0.3	2.2	2.3	0.2	-0.8
Osteoporosis (self-reported)	1.7	2.1	7.4	0.3	-1.6	-0.8	0.2	2.7
Pain type(s) experienced in last month: Hip pain	1.7	2.2	6.3	1.0	-0.7	0.2	-2.5	1.8
Glaucoma (self-reported)	1.6	1.8	3.9	-2.0	0.9	0.1	1.1	-1.8
Chest pain or discomfort	1.6	2.3	9.5	0.7	-0.9	-0.4	-0.8	3.1
Alcohol drinker status: Previous	1.6	1.8	5.2	-0.3	-2.3	0.3	0.5	1.8
High cholesterol (Self-reported)	1.5	2.6	11.7	-0.0	-0.1	0.1	-1.1	3.4
Diabetes (father)	1.4	1.7	4.4	1.5	0.4	-1.1	0.6	2.1
Diabetes (self-reported)	1.4	2.2	6.2	1.9	-0.7	-0.7	-0.6	2.5
Medication: Lansoprazole	1.4	1.6	5.5	0.4	-1.3	-2.4	0.1	0.7
Mouth/teeth dental problems: Mouth ulcers	1.4	2.3	4.6	1.4	-1.1	-2.2	0.7	1.8
Medication: Blood pressure	1.4	2.6	5.6	2.4	-1.1	1.0	-0.4	2.3
Medication: Atorvastatin	1.4	1.7	2.5	1.6	1.3	0.9	1.2	1.5
Supplements: Calcium	1.4	1.6	3.5	-0.3	-1.7	0.4	1.0	1.9
Falls in the last year	1.3	1.8	4.5	-0.1	-1.5	-1.5	0.1	2.1
Comparative body size at age 10	1.3	3.6	5.7	-2.3	-1.3	-2.4	0.5	-2.3
Overall health rating	1.3	2.9	6.3	1.5	0.6	2.5	-0.7	2.3
Age at last live birth	1.3	1.8	8.6	0.7	-0.3	-0.2	-2.9	-0.0
Osteoarthritis (self-reported)	1.3	1.7	3.3	-1.0	0.0	1.7	1.0	-1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.7	6.2	-2.5	0.4	-0.5	1.8	-1.9
Average weekly champagne plus white wine intake	1.3	1.8	4.4	-1.7	-0.0	-2.1	-0.6	-1.2
Neuroticism (Nagel 2018)	1.2	2.7	5.7	1.8	0.1	0.1	-2.4	2.2
Lung FEV1/FVC ratio	1.2	6.2	11.8	-3.4	2.3	2.2	-0.8	-2.9
Tense / ‘highly strung’	1.2	2.0	4.5	1.9	-1.0	0.0	1.0	2.1
Mouth/teeth dental problems: Loose teeth	1.2	1.4	2.4	1.3	-1.5	-0.9	0.7	1.3
Emphysema/chronic bronchitis	1.2	1.4	3.1	1.7	-0.7	-1.8	0.5	0.1
Illnesses of father: None of the above (group 1)	1.2	1.4	4.5	0.4	0.1	-2.1	1.2	-1.1
Mother’s age at death	1.2	1.5	3.9	-2.0	0.8	0.7	-0.3	-1.5
Eye problems/disorders: Glaucoma	1.2	1.5	1.8	-1.3	1.2	1.2	1.0	-1.3
Alzheimer’s Disease (in mother)	1.1	1.3	2.3	0.7	-1.5	-1.5	1.2	0.3
Body Mass Index (BMI) (2010)	1.1	1.5	4.5	-0.7	-1.0	-2.1	1.1	0.8
Sensitivity / hurt feelings	1.1	1.8	2.9	1.0	1.2	1.6	-1.7	1.1
Ever used hormone-replacement therapy (HRT)	1.1	1.4	4.0	2.0	0.8	0.0	-0.7	1.3
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	2.6	0.5	-0.6	0.6	-1.5	1.6
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.2	2.9	-0.3	-0.0	0.9	1.7	-1.5
Illnesses of mother	1.1	1.3	2.9	1.4	-0.6	1.7	1.1	-0.5
Number of full brothers	1.1	1.4	2.7	1.5	-0.5	1.6	1.0	0.9
Wheeze or whistling in the chest in last year	1.1	2.0	4.2	1.1	-0.3	1.4	-2.0	1.6
Family relationship satisfaction	1.1	1.3	2.8	0.7	-1.2	-0.3	-1.7	1.3
Long-standing illness, disability or infirmity	1.1	1.7	3.5	1.0	-1.7	0.5	0.7	1.9
Irritability	1.1	1.9	2.6	1.3	-1.3	-1.1	-1.5	1.6
Unable to work because of sickness or disability	1.1	1.5	2.9	-1.4	-0.5	0.4	1.4	1.7
Bipolar Disorder (2011)	1.0	0.9	2.8	0.6	-0.4	1.7	1.1	-0.2
Allergy or Eczema	1.0	2.7	5.1	-0.8	-2.3	-1.7	1.4	1.7
Impedance of leg (right)	1.0	5.1	13.0	3.1	-1.6	0.3	-0.5	3.6
Hayfever, allergic rhinitis or eczema	1.0	2.2	4.9	-2.2	-1.6	-1.8	0.1	0.1
Chronic bronchitis/emphysema (father)	1.0	1.2	2.5	1.0	0.9	-0.0	1.2	1.6
Impedance of leg (left)	1.0	4.6	11.5	2.7	-2.1	0.1	0.0	3.4
Financial difficulties in last 2 years	1.0	1.4	2.8	-1.6	-0.4	-1.7	1.1	-0.3
Medication: Simvastatin	1.0	1.4	5.5	0.1	-0.8	-0.7	-0.7	2.3
Ever highly irritable/argumentative for 2 days	1.0	1.2	3.3	0.8	-0.1	-1.1	-1.0	1.8
Birth weight	1.0	2.1	3.2	0.9	1.0	1.7	1.7	-1.8
Worry too long after embarrassment	1.0	1.7	5.1	1.7	0.7	2.3	0.3	0.2
Eye problems/disorders: None of the above	1.0	1.1	3.0	-1.3	-0.2	-0.8	1.7	0.2
Neck or shoulder pain in last month	1.0	1.5	2.8	0.8	1.2	1.7	-1.1	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	4.9	-0.2	0.1	-0.9	-0.5	2.2
Medication: Aspirin	1.0	1.2	2.4	1.5	-0.0	-1.0	-1.3	1.1
Medication: Bendroflumethiazide	1.0	1.5	3.4	1.1	-1.5	-0.4	0.8	1.8
Illnesses of father: High blood pressure	1.0	1.3	3.0	0.8	0.1	1.3	-1.7	1.0
Alcohol drinker status: Never	1.0	1.2	2.6	-0.3	-0.9	-1.6	-1.1	1.0
Fractured/broken bones in last 5 years	1.0	1.3	2.0	1.0	-1.2	-1.2	-0.7	1.4
Commuting to job workplace: Cycle	1.0	1.2	2.7	1.2	-0.8	0.8	-1.7	0.8
Pain experienced in last month	1.0	1.7	5.6	-0.9	-0.1	-1.1	0.9	-2.4
Worry (Nagel 2018)	0.9	1.9	5.2	2.3	0.2	0.9	-0.2	1.8
Fasting Glucose	0.9	1.1	2.4	-0.6	-1.5	-1.3	0.7	0.8
LDL Cholesterol	0.9	1.5	4.8	2.2	-0.4	1.4	-0.3	0.6
Cardiovascular Disease	0.9	3.0	8.8	2.4	-0.4	0.6	-0.3	3.0
Taking other prescription medications	0.9	1.3	4.2	-0.4	-0.1	1.0	1.1	2.0
High blood pressure	0.9	2.4	6.1	2.0	-0.9	1.1	-0.6	2.5
Mouth/teeth dental problems	0.9	1.4	3.2	-0.1	0.7	1.4	1.1	-1.8
Father’s age at death	0.9	1.2	2.7	-1.5	0.5	0.9	-0.3	-1.6
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	4.4	2.1	0.4	1.1	-0.0	1.3
Pulse rate	0.9	1.6	4.7	1.0	-1.1	-0.9	0.2	2.2
Pulse wave reflection index	0.9	1.1	2.5	-1.3	-0.8	0.6	-0.1	-1.6
Blood clot in the leg (DVT)	0.9	1.2	5.3	0.3	-0.3	-0.4	-0.5	2.3
Number of children fathered	0.9	1.1	1.8	0.4	1.3	1.2	-0.5	-1.3
Angina (self-reported)	0.9	1.2	3.3	0.8	-1.2	0.7	-0.2	1.8
Mean time to correctly identify matches	0.9	1.6	3.7	-1.3	-1.9	-0.8	-1.3	0.6
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	2.9	-0.0	1.7	-0.6	-1.4	0.5
Supplements: Vitamin C	0.9	1.1	3.4	-1.1	-0.5	-1.8	-0.8	-0.2
Hypertension (Self-reported)	0.9	2.4	5.6	2.0	-0.7	1.4	-0.6	2.4
Average weekly red wine intake	0.9	1.3	3.3	-1.8	-0.6	-1.5	-0.3	-0.9
Loneliness, isolation	0.9	1.3	2.8	1.7	-0.6	-0.8	-0.2	1.6
Commuting to job workplace: Walk	0.9	0.9	2.8	0.8	1.1	1.7	0.2	-0.1
Tinnitus: Yes, now most or all of the time	0.9	1.1	3.6	-0.2	0.5	-1.9	-1.2	0.3
Age started oral contraceptive pill	0.9	1.2	2.7	0.6	-1.6	-0.6	-0.2	1.6
Myopia	0.9	1.4	2.9	-1.7	0.7	-1.7	-0.1	0.7
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	5.0	0.5	-0.2	-0.5	-0.4	2.2
Depressed Affect (Nagel 2018)	0.8	1.7	5.9	0.9	-0.0	-0.9	-2.4	1.1
Systolic blood pressure, automated reading	0.8	2.3	5.0	-0.9	2.2	2.2	-0.4	-0.9
Medication: Levothyroxine sodium	0.8	1.4	3.1	-0.5	1.4	1.0	0.6	1.8
Alcohol usually taken with meals	0.8	1.2	3.5	-1.9	0.3	-1.0	-0.9	-0.8
Hearing difficulty/problems with background noise	0.8	1.3	3.0	0.2	-1.1	-1.7	-1.5	0.4
Illnesses of siblings	0.8	1.2	3.1	0.8	-1.0	-1.8	1.0	0.5
Noisy workplace	0.8	0.9	2.2	-0.5	-1.3	-0.7	-0.3	-1.5
Prospective memory result	0.8	1.0	2.3	-0.6	-1.3	-0.3	1.5	-0.8
Age at first live birth	0.8	1.4	3.7	1.2	-0.7	-1.9	-0.6	-0.9
Health satisfaction	0.8	1.0	2.8	-1.0	0.7	0.7	0.4	-1.7
Shortness of breath walking on level ground	0.8	1.0	2.5	0.4	-1.6	-1.1	-0.9	-0.2
Medication for pain relief, constipation, heartburn	0.8	1.4	2.5	-0.4	1.6	1.5	0.8	-1.2
Alcohol intake frequency.	0.8	1.8	4.6	-0.1	-2.0	-0.6	-0.5	2.1
Comparative height size at age 10	0.8	4.4	10.2	3.2	-1.9	0.7	-1.7	2.2
Number of full sisters	0.8	1.0	1.3	0.9	-1.2	1.1	0.5	1.0
Medication: Aspirin	0.8	1.1	2.2	1.5	0.3	-0.9	-1.1	1.0
Friendships satisfaction	0.8	1.0	2.8	1.7	0.8	0.8	0.2	0.9
Eye problems/disorders: Cataract	0.8	0.9	2.3	1.5	-0.1	-0.3	-1.4	-0.3
Commuting to job workplace: Public transport	0.8	1.0	2.6	0.2	-1.6	-1.1	-1.0	-0.2
Vascular/heart problems diagnosed by doctor	0.8	2.1	5.4	-1.6	0.4	-1.4	0.3	-2.3
Primary Biliary Cirrhosis	0.7	1.0	3.7	-0.6	-0.0	0.5	1.9	0.7
Average weekly spirits intake	0.7	0.9	1.9	-1.3	-0.4	-1.4	-0.2	0.8
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.3	1.0	-0.3	1.5	0.3	1.3
Angina	0.7	1.0	3.0	0.5	-1.2	0.3	-0.3	1.7
Townsend deprivation index at recruitment	0.7	1.0	2.9	-0.6	-1.2	0.1	1.7	-0.1
Maternal smoking around birth	0.7	1.0	3.5	-1.9	1.2	-0.6	-0.2	-0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	2.4	1.6	-0.6	0.9	-0.5	0.9
Serious illness, injury or assault to yourself	0.7	0.8	2.0	1.4	-0.3	1.4	-0.2	-0.1
Medication: Atenolol	0.7	0.9	3.8	0.5	-0.5	2.0	0.2	0.0
Hair/balding pattern: Pattern 3	0.7	1.1	3.5	-0.6	-1.1	-1.9	-0.2	-0.5
Depression (self-reported)	0.7	0.8	1.4	1.1	-0.1	0.5	-1.0	1.2
Standing height	0.7	6.7	20.3	4.5	0.1	2.8	-1.5	1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	1.0	2.2	-0.4	-0.7	0.5	1.3	1.5
Medication: Seretide 50 evohaler	0.7	0.8	2.1	-0.3	1.1	1.4	-0.7	-0.2
Heart disease (mother)	0.7	0.8	2.2	0.5	-0.1	-0.2	-1.2	1.5
Pulse rate, automated reading	0.7	2.2	3.8	1.9	-1.0	-0.5	-1.5	2.0
Breast cancer (self-reported)	0.7	0.8	1.4	-1.2	-1.2	-0.0	-0.5	1.0
Medication: Gliclazide	0.7	0.7	2.9	0.5	0.1	-0.4	-0.6	1.7
Ever taken oral contraceptive pill	0.7	0.8	2.6	-0.4	-0.5	-1.6	1.0	0.1
Diastolic blood pressure, automated reading	0.7	2.1	5.0	-0.9	1.1	2.2	-0.7	-1.8
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	1.8	-0.4	-0.9	-1.1	0.3	1.4
Alzheimer’s Disease (in father)	0.6	0.6	1.2	-0.9	-0.5	0.9	0.3	-1.1
Coronary Artery Disease (CAD)	0.6	0.7	2.0	1.0	-0.4	-0.6	0.1	1.4
Crohns Disease (2012)	0.6	1.0	3.2	0.0	-0.1	-0.1	1.2	-1.8
Lupus	0.6	0.9	3.1	0.1	0.6	-0.3	-1.8	0.9
Neuroticism (2016)	0.6	0.9	1.6	0.5	0.4	-1.1	1.1	1.3
Relative age of first facial hair	0.6	1.2	3.1	1.5	0.4	0.3	1.8	0.6
Medication for hormone replacement therapy	0.6	0.6	1.7	1.3	0.1	0.9	-0.5	0.6
Vitamin and mineral supplements	0.6	0.9	3.8	-0.4	1.9	0.6	-0.2	0.3
Pack years adult smoking proportion	0.6	0.9	3.4	-0.3	0.7	1.9	0.1	-0.8
Supplements: Glucosamine	0.6	0.8	2.2	0.3	0.7	0.9	-1.5	-0.6
Sitting height	0.6	4.2	9.2	3.0	0.9	-0.8	-2.5	2.0
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	2.7	0.5	0.7	1.6	-0.6	0.4
Pain all over the body in last month	0.6	0.6	2.2	-0.7	-1.5	0.2	0.6	0.4
Breastfed as a baby	0.6	0.7	1.5	-0.5	0.8	-0.9	0.5	-1.2
Medication: Ventolin 100micrograms inhaler	0.6	0.8	3.1	0.3	0.3	-0.1	-1.8	0.8
Medication: Omeprazole	0.6	0.7	1.8	-0.4	-0.4	-1.1	-0.6	1.3
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.8	0.0	1.3	0.0	-1.1	0.8
Illnesses of father: Heart disease	0.6	0.9	2.3	-1.5	-0.0	1.3	-0.6	-0.2
Illnesses of siblings: Diabetes	0.6	0.7	2.5	-0.9	0.1	-0.3	-1.6	0.5
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.1	-1.0	-0.6	-0.1	-0.4	-1.4
Mood swings	0.6	1.2	2.7	-1.0	-1.7	-1.4	-0.3	0.2
Ever had bowel cancer screening	0.6	0.7	1.5	-1.0	-0.9	-1.2	-0.2	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.2	-0.8	1.1	0.5	0.5	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.8	-0.5	-1.1	-1.4	0.0	-0.7
Number of self-reported non-cancer illnesses	0.6	1.0	3.6	0.7	-0.8	0.5	0.3	1.9
Ever smoked	0.6	1.1	4.5	-0.3	-0.6	2.1	-0.7	0.1
Heart disease (siblings)	0.6	0.7	2.5	0.0	-0.1	0.2	-1.1	1.6
Schizophrenia vs Biploar Disorder	0.5	0.7	1.7	-0.4	-1.3	-1.1	0.6	0.1
Reaction Time	0.5	1.0	2.4	0.5	-1.2	-0.3	-1.5	0.9
Verbal and Numeric Reasoning (VNR)	0.5	1.2	4.4	0.7	0.9	2.1	0.4	-0.2
Waist Hip Ratio (WHR)	0.5	2.4	4.5	1.1	-1.9	1.7	-2.1	-0.2
Systolic Blood Pressure	0.5	2.7	8.8	1.1	1.6	3.0	-0.7	0.7
Respiratory disease	0.5	1.0	2.1	1.5	0.3	1.2	0.2	1.2
Neuroticism	0.5	1.3	2.8	1.5	0.6	-0.0	-0.9	1.7
Medication: Co-codamol	0.5	0.6	1.9	0.8	1.4	0.3	-0.6	0.3
Average weekly fortified wine intake	0.5	0.6	1.4	-0.5	-1.2	-0.7	-0.3	1.0
Multivitamins +/- minerals	0.5	0.7	1.9	1.0	-1.4	-0.6	0.3	-0.4
Stomach or abdominal pain in last month	0.5	0.6	0.9	-0.8	-1.0	-0.8	0.7	0.8
High blood pressure (mother)	0.5	0.7	1.1	-1.0	1.0	0.4	0.9	-0.6
Nervous feelings	0.5	1.0	2.1	1.5	0.5	0.9	1.2	0.6
Hair/balding pattern: Pattern 2	0.5	0.6	1.6	-0.2	-0.2	1.2	0.1	1.3
Had other major operations	0.5	0.6	1.8	0.9	0.4	1.3	-0.0	-0.5
Medication: Paracetamol	0.5	0.8	2.2	-1.0	-0.8	-1.5	0.3	0.3
Qualifications: College or University degree	0.5	1.5	3.6	-0.8	0.7	-1.5	0.9	-1.9
Migraine (self-reported)	0.5	0.7	1.0	-1.0	1.0	-0.7	0.7	-0.6
Medication: Ibuprofen	0.5	0.6	1.6	-0.2	-0.5	-0.5	-1.0	-1.3
Knee pain experienced in last month	0.5	0.8	1.5	1.2	0.8	0.8	-1.0	0.6
Smoking status: Previous	0.5	0.8	1.8	0.9	0.8	0.8	0.3	-1.4
Mineral and other dietary supplements	0.5	0.7	1.5	0.8	-0.3	0.5	0.9	1.2
Miserableness	0.5	0.9	1.6	-0.7	1.3	-0.3	-1.2	-1.1
Medication: Lisinopril	0.5	0.6	1.5	0.1	-1.0	-0.8	1.2	0.2
Basal cell carcinoma (self-reported)	0.5	0.6	2.4	0.1	-0.6	-0.3	-0.4	1.6
Pack years of smoking	0.5	0.7	2.7	-0.2	0.5	1.6	0.0	-0.7
Impedance of whole body	0.5	2.6	5.6	2.4	-1.6	-0.1	0.5	2.2
Intelligence (Savage-Jansen 2018)	0.4	1.2	2.6	0.6	1.2	1.6	1.2	0.4
Schizophrenia (2018)	0.4	0.8	2.0	-1.4	-0.6	-0.8	-0.9	-0.6
Alzheimer’s Disease (including proxy)	0.4	0.5	1.6	-0.5	-1.3	-0.4	0.2	-0.8
Prostate Cancer	0.4	0.6	1.9	-0.5	-0.9	-0.2	-1.4	-0.0
Ulcerative Colitis	0.4	0.6	1.4	-0.6	-0.7	-1.2	0.0	0.6
Blood Eosinophil Count	0.4	2.8	7.3	-1.9	-1.6	-2.7	-0.5	0.6
BMI	0.4	2.5	5.2	-2.1	1.4	0.7	-0.4	-2.3
Smoking Status	0.4	1.0	2.3	-0.8	0.7	1.5	-1.1	-0.7
Hypothyroidism (self reported)	0.4	0.8	3.0	-1.7	0.2	-0.6	-0.4	0.7
Medication: Metformin	0.4	0.6	2.0	-0.2	0.2	-0.9	0.1	1.4
Fed-up feelings	0.4	0.6	2.2	-0.4	-0.0	-0.5	-1.5	0.8
Age when periods started (menarche)	0.4	0.9	3.2	-0.2	1.8	0.8	0.3	-0.7
Body mass index (BMI)	0.4	1.6	3.5	-1.7	1.9	-0.3	-0.6	-1.0
Forced vital capacity (FVC)	0.4	1.6	3.6	-0.4	-1.8	-1.0	1.9	0.4
Heart attack	0.4	0.5	0.9	0.9	-0.9	0.4	-0.7	0.6
Arm fat percentage (right)	0.4	1.6	3.5	-1.9	1.8	0.2	-0.1	-1.1
Trunk fat-free mass	0.4	2.1	5.0	0.9	1.6	2.2	-1.4	-0.5
Worrier / anxious feelings	0.4	0.7	2.4	0.1	1.0	1.5	-0.0	0.3
Mouth/teeth dental problems: Dentures	0.4	0.7	2.7	0.6	-0.5	0.3	-1.6	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.1	0.1	-0.8	-0.6	-0.3	-1.1
Trunk predicted mass	0.4	2.1	4.9	0.8	1.6	2.2	-1.4	-0.5
Hair/balding pattern: Pattern 4	0.4	1.1	3.6	0.6	0.4	1.1	1.9	0.0
Headache pain in last month	0.4	0.7	2.6	-0.3	1.6	0.2	0.0	0.9
Suffer from ‘nerves’	0.4	0.6	2.5	0.1	0.5	0.5	1.6	0.1
Wears glasses or contact lenses	0.4	0.4	0.9	0.0	0.9	-0.7	0.5	0.8
Supplements: Fish oil (including cod liver oil)	0.4	0.6	1.2	-0.4	0.9	-0.2	-0.8	-1.1
Medication: Paracetamol	0.4	0.7	1.4	-0.6	-1.1	-1.2	-0.3	0.5
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.1	-1.1	-0.4	-0.5	0.5	-0.8
Ever depressed for a whole week	0.4	0.5	1.4	0.5	-0.6	1.2	-0.6	0.5
Heart attack/myocardial infarction (self-reported)	0.4	0.5	0.8	0.9	-0.7	0.4	-0.8	0.5
Bipolar Disorder (2018)	0.3	0.5	0.7	0.2	0.8	0.8	0.6	0.7
Ulcerative Colitis (UC)	0.3	0.6	1.2	-1.1	-0.7	-1.1	-0.1	0.7
Major Depression (MDD)	0.3	0.4	1.3	-0.5	1.1	-0.0	-0.7	0.3
Breast Cancer	0.3	0.7	2.3	0.2	0.4	-1.5	-1.1	-0.3
Age at First Birth	0.3	0.4	1.1	0.4	-0.2	0.2	-0.7	-1.1
Height	0.3	6.4	14.1	3.8	1.3	3.6	-1.6	1.0
Number of treatments/medications taken	0.3	0.5	1.6	0.1	-0.5	0.5	-0.3	1.3
Ever had hysterectomy (womb removed)	0.3	0.3	1.1	-0.1	1.0	-0.1	-0.6	0.4
Leg fat-free mass (left)	0.3	1.7	3.4	0.5	1.8	1.5	-1.4	-0.9
Current tobacco smoking	0.3	0.5	2.1	-1.4	0.1	0.6	-0.2	0.2
Relative age voice broke	0.3	0.4	1.5	0.5	1.2	-0.3	0.2	0.3
Qualifications: CSEs or equivalent	0.3	0.4	1.1	-0.7	0.2	-0.4	-0.5	1.0
Leg predicted mass (left)	0.3	1.7	3.1	0.6	1.8	1.4	-1.4	-1.0
Past tobacco smoking	0.3	0.5	1.9	-0.3	-0.0	-1.4	0.4	0.7
Allergy	0.3	0.7	1.0	1.0	0.7	0.9	0.4	-0.9
Neuroticism score	0.3	0.6	1.2	1.0	0.3	0.8	-0.3	1.1
Number of live births	0.3	0.5	0.8	-0.1	0.7	0.9	0.7	0.7
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	2.3	-1.1	-1.2	-0.4	1.5	-0.1
Impedance of arm (left)	0.3	1.2	4.2	2.1	-0.6	-0.3	1.0	0.5
Arm fat mass (right)	0.3	1.3	3.3	-1.2	1.8	0.5	-0.9	-0.8
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.5	-0.9	0.3	-0.6	0.7	1.2
Medication: Amlodipine	0.3	0.5	1.6	0.4	-0.7	-0.3	-1.2	-0.0
Forced vital capacity (FVC), Best measure	0.3	1.1	3.9	-0.3	-1.1	-0.5	2.0	0.3
Arm fat-free mass (right)	0.3	1.5	4.6	1.1	0.8	1.0	-2.1	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.0	0.2	0.3	0.6	-1.0	-0.0
Arm predicted mass (right)	0.3	1.4	4.5	1.0	0.7	1.1	-2.1	0.2
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.0	0.9	-0.1	-0.0	0.0	1.0
Whole body fat-free mass	0.3	1.8	3.4	0.7	1.5	1.9	-1.5	-0.7
Leg fat-free mass (right)	0.3	1.4	2.7	0.4	1.6	1.2	-1.1	-1.3
Arm fat percentage (left)	0.3	1.3	3.1	-1.4	1.8	-0.2	-0.3	-1.1
Smoking status: Current	0.3	0.5	1.6	-1.3	-0.1	0.6	-0.7	0.5
Whole body water mass	0.3	1.8	3.4	0.6	1.5	1.9	-1.5	-0.8
Leg predicted mass (right)	0.3	1.4	2.5	0.4	1.6	1.2	-1.1	-1.3
Arm fat mass (left)	0.3	1.1	3.7	-0.9	1.9	0.3	-0.7	-0.7
Financial situation satisfaction	0.3	0.4	1.3	-0.5	-1.1	-0.5	0.2	0.1
Basal metabolic rate	0.3	1.7	2.9	0.8	1.6	1.7	-1.5	-0.6
Arm fat-free mass (left)	0.3	1.4	2.8	0.6	1.1	1.7	-1.6	0.0
Arm predicted mass (left)	0.3	1.4	3.5	0.5	1.0	1.5	-1.9	-0.1
Mean Putamen Volume	0.2	0.3	0.6	0.7	0.2	0.8	0.2	0.3
Schizophrenia (2014)	0.2	0.4	0.8	-0.6	-0.9	-0.9	-0.4	0.3
Blood Platelet Count	0.2	2.2	3.2	-1.8	1.8	-0.9	-1.7	-0.8
Trunk fat mass	0.2	0.7	1.8	-0.2	1.4	0.4	-1.3	0.3
Number of incorrect matches in round	0.2	0.3	0.7	-0.5	0.3	0.8	0.1	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.8	0.8	-0.2	-0.1	0.2	0.9
Had menopause	0.2	0.2	0.5	0.7	0.1	0.1	0.5	0.5
Fluid intelligence score	0.2	0.3	0.9	0.1	0.8	1.0	-0.1	-0.0
Weight	0.2	1.2	3.1	0.5	1.8	0.9	-1.3	-0.2
Impedance of arm (right)	0.2	1.1	2.6	1.6	0.2	0.4	1.6	0.2
Hip circumference	0.2	1.0	3.0	-0.2	1.7	-0.4	-1.2	0.5
Time employed in main current job	0.2	0.2	0.8	0.3	0.1	-0.4	0.1	-0.9
Asthma	0.2	0.4	1.3	0.6	0.4	1.1	0.4	0.4
Medication: Cholesterol lowering	0.2	0.3	1.2	-0.4	0.3	0.2	0.1	1.1
Lung cancer (father)	0.2	0.2	0.7	0.1	0.2	0.9	0.2	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	2.2	-0.9	-0.6	-0.3	1.5	-0.1
Length of working week for main job	0.2	0.2	0.6	-0.5	0.3	0.1	0.2	-0.8
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.6	-0.3	0.8	-0.5	-0.0	0.5
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.1	-0.0	-0.2	-0.3	-0.3	-1.1
Leg fat percentage (right)	0.2	0.7	1.7	-0.3	0.8	-0.4	-0.9	1.3
Medication: Blood pressure	0.2	0.3	0.8	0.6	-0.4	0.3	-0.2	0.9
Whole body fat mass	0.2	0.7	1.7	-0.5	1.3	0.1	-1.3	0.2
Leg fat mass (right)	0.2	0.8	2.2	-0.4	1.0	0.1	-1.5	0.8
Asthma (self-reported)	0.2	0.5	1.5	0.6	0.6	1.2	0.3	0.2
Number of operations (self-reported)	0.2	0.4	1.2	0.5	0.1	0.1	0.5	1.1
Risk taking	0.2	0.4	0.8	-0.6	-0.2	-0.8	0.9	-0.0
Leg fat mass (left)	0.2	0.6	1.6	-0.5	0.9	0.1	-1.3	0.7
Bipolar Disorder or Schizophrenia	0.1	0.2	0.9	-0.9	0.0	-0.0	-0.3	0.0
Crohns Disease (2017)	0.1	0.2	0.4	0.4	0.4	0.3	0.2	-0.7
Irritable Bowel Disease (IBD)	0.1	0.2	0.7	-0.5	-0.2	-0.9	0.1	-0.0
Rheumatoid Arthritis	0.1	0.2	0.4	0.1	-0.4	0.0	-0.4	0.7
Blood Red Count	0.1	1.0	2.2	1.1	-0.9	0.5	-0.6	1.5
Chronotype (morning person)	0.1	0.1	0.7	0.8	0.0	0.1	0.0	0.2
Tanning	0.1	1.5	2.4	-1.4	0.7	-1.6	0.7	-1.4
Trunk fat percentage	0.1	0.5	1.0	-0.3	1.0	-0.1	-1.0	0.4
Waist circumference	0.1	0.3	1.4	0.0	0.4	0.3	-1.2	0.1
Qualifications: None of the above	0.1	0.2	0.6	0.6	-0.8	-0.1	-0.2	0.5
Happiness	0.1	0.2	0.3	-0.6	-0.3	-0.1	-0.5	-0.2
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.5	0.2	-0.5	-0.7	0.1	-0.6
Birth weight of first child	0.1	0.3	1.1	-0.5	-0.1	-1.0	0.1	0.1
Peak expiratory flow (PEF)	0.1	0.2	0.8	-0.0	-0.2	-0.4	0.0	0.9
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.4	0.1	-0.2	-0.6	-0.7	0.2
Body fat percentage	0.1	0.5	1.0	-0.7	1.0	-0.3	-0.8	0.5
Had major operations	0.1	0.1	0.4	0.1	0.5	-0.0	-0.0	0.6
Qualifications: nursing, teaching	0.1	0.2	0.8	-0.1	-0.4	0.2	0.9	-0.4
Leg fat percentage (left)	0.1	0.5	1.2	-0.6	0.8	-0.3	-0.6	1.1
Blood White Count	0.0	0.3	0.6	0.4	0.8	-0.3	-0.7	0.5
Hair Pigment	0.0	1.0	1.9	0.5	1.4	0.5	1.0	1.2

Hub : Genes

MEOX2

Models

Trait associations