Best TWAS P=0 · Best GWAS P=0 conditioned to NaN
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | WNT16 | 0.09 | 0.04 | enet | 32 | 0.04 | 8.1e-06 | -29.6 | -25.2 | 1.2e-140 | -0.19 | 0.81 | 0.06 | TRUE |
| 2 | GTEx | Adipose Subcutaneous | CPED1 | 0.10 | 0.02 | enet | 26 | 0.04 | 6.2e-04 | 39.7 | 50.9 | 0.0e+00 | 0.35 | 0.42 | 0.23 | FALSE |
| 3 | GTEx | Artery Tibial | CPED1 | 0.08 | 0.00 | lasso | 4 | 0.00 | 1.4e-01 | 80.1 | 73.8 | 0.0e+00 | 0.86 | 0.03 | 0.91 | TRUE |
| 4 | GTEx | Cells Transformed fibroblasts | CPED1 | 0.20 | 0.12 | lasso | 5 | 0.16 | 7.6e-12 | 47.4 | 46.1 | 0.0e+00 | 0.27 | 1.00 | 0.00 | TRUE |
| 5 | GTEx | Esophagus Muscularis | TSPAN12 | 0.19 | 0.13 | lasso | 5 | 0.14 | 6.2e-09 | 6.9 | 5.4 | 5.5e-08 | 0.06 | 1.00 | 0.00 | TRUE |
| 6 | GTEx | Esophagus Muscularis | CPED1 | 0.21 | 0.06 | lasso | 6 | 0.03 | 6.9e-03 | 4.0 | 5.9 | 3.2e-09 | 0.05 | 0.86 | 0.04 | TRUE |
| 7 | GTEx | Nerve Tibial | CPED1 | 0.09 | 0.03 | lasso | 3 | 0.06 | 6.4e-05 | 45.4 | 30.6 | 2.7e-206 | 0.16 | 0.10 | 0.04 | TRUE |
| 8 | GTEx | Skin Not Sun Exposed Suprapubic | FAM3C | 0.15 | 0.09 | lasso | 7 | 0.10 | 6.2e-06 | -28.2 | 31.6 | 7.4e-219 | 0.27 | 0.75 | 0.09 | TRUE |
| 9 | GTEx | Skin Sun Exposed Lower leg | CPED1 | 0.05 | 0.01 | lasso | 4 | 0.02 | 1.3e-02 | 4.9 | 15.3 | 1.1e-52 | 0.04 | 0.27 | 0.04 | FALSE |
| 10 | GTEx | Skin Sun Exposed Lower leg | FAM3C | 0.16 | 0.07 | enet | 27 | 0.10 | 1.6e-08 | -29.7 | 50.6 | 0.0e+00 | 0.47 | 0.66 | 0.32 | FALSE |
| 11 | METSIM | Adipose | FAM3C | 0.12 | 0.13 | bslmm | 376 | 0.13 | 7.0e-19 | -34.3 | 38.0 | 0.0e+00 | 0.39 | 1.00 | 0.00 | FALSE |
| 12 | METSIM | Adipose | ING3 | 0.02 | 0.00 | blup | 352 | 0.00 | 6.0e-02 | 3.3 | 15.1 | 2.5e-51 | 0.05 | 0.06 | 0.03 | TRUE |
| 13 | NTR | Blood | C7orf58 | 0.04 | 0.02 | lasso | 7 | 0.03 | 9.5e-10 | 47.9 | 34.3 | 1.1e-257 | 0.19 | 1.00 | 0.00 | TRUE |
| 14 | ROSMAP | Brain Pre-frontal Cortex | CPED1 | 0.05 | 0.01 | blup | 447 | 0.03 | 6.1e-05 | 2.2 | -48.8 | 0.0e+00 | -0.39 | 0.37 | 0.27 | FALSE |
| 15 | ROSMAP | Brain Pre-frontal Cortex | FAM3C | 0.07 | 0.02 | blup | 369 | 0.04 | 1.6e-05 | 48.7 | -11.5 | 1.5e-30 | -0.24 | 0.52 | 0.06 | FALSE |
| 16 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | C7orf58 | 0.08 | 0.01 | blup | 158 | 0.01 | 5.1e-02 | 49.5 | 50.3 | 0.0e+00 | 0.45 | 0.05 | 0.23 | TRUE |
| 17 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ING3 | 0.05 | 0.02 | blup | 41 | 0.02 | 3.5e-03 | -2.1 | 5.4 | 6.9e-08 | 0.00 | 0.12 | 0.06 | FALSE |