TWAS hub - C7orf58

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0439	0.0127	3.8e-09	0.017	0.028	0.024	0.028	0.029	1.8e-06	2.2e-09	2.7e-08	1.5e-09	9.5e-10
2	TCGA	Ovarian Serous Cystadenocarcinoma	0.0850	0.0520	5.6e-03	0.014	0.012	0.009	NA	0.001	3.8e-02	5.1e-02	7.8e-02	NA	2.5e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Heel T-Score	233.0	1853.3	2530.1	34.3	50.3
Heel bone mineral density (BMD) T-score, automated (left)	154.5	350.3	466.6	15.3	21.6
Heel bone mineral density (BMD) T-score, automated (right)	147.3	337.7	462.2	14.6	21.5
Fractured/broken bones in last 5 years	25.5	32.9	43.0	-4.8	-6.6
Hand grip strength (right)	11.1	30.2	36.2	-6.0	-4.9
Hand grip strength (left)	9.0	23.8	29.7	-5.4	-4.2
Waist Hip Ratio (WHR)	8.4	37.7	41.2	-5.8	-6.4
Loneliness, isolation	7.7	10.7	11.2	-3.4	-3.2
Ever had prostate specific antigen (PSA) test	7.5	8.7	14.3	-1.8	-3.8
Diabetes (mother)	5.2	6.6	7.2	-2.5	-2.7
Breast cancer (self-reported)	5.2	6.2	6.3	-2.5	-2.5
Mood swings	5.1	9.1	9.2	-3.0	-3.0
Neuroticism score	4.5	9.5	12.2	-2.6	-3.5
Breastfed as a baby	4.4	5.5	6.1	-2.5	-2.2
Medication for pain relief, constipation, heartburn	4.3	7.3	13.7	0.9	3.7
Depression (Nagel 2018)	4.1	6.2	6.4	-2.5	-2.5
Depressed Affect (Nagel 2018)	4.0	8.4	8.5	-2.9	-2.9
Neck or shoulder pain in last month	3.9	5.6	8.4	-1.7	-2.9
Taking other prescription medications	3.7	5.7	8.0	-1.8	-2.8
Hearing difficulty/problems with background noise	3.7	5.9	11.3	3.4	0.6
Pulse rate	3.7	6.2	7.8	-2.2	-2.8
Number of full brothers	3.5	4.3	6.0	1.6	2.5
Neuroticism (2016)	3.4	4.9	8.6	-1.1	-2.9
Fed-up feelings	3.1	5.7	7.7	-1.9	-2.8
Ever had bowel cancer screening	3.1	3.7	4.1	-1.8	-2.0
Maternal smoking around birth	2.9	4.3	7.1	-1.2	-2.7
Guilty feelings	2.9	4.3	5.4	-1.8	-2.3
Basal cell carcinoma (self-reported)	2.9	3.5	6.2	2.5	0.9
Comparative height size at age 10	2.7	14.9	17.9	-3.5	-4.2
Tinnitus: Yes, now most or all of the time	2.7	3.1	4.7	2.2	1.2
Neuroticism (Nagel 2018)	2.6	6.1	7.8	-2.1	-2.8
Frequency of unenthusiasm / disinterest in last 2 weeks	2.6	3.5	4.4	-2.1	-1.6
Heart disease (mother)	2.6	3.2	3.7	-1.6	-1.9
Nervous feelings	2.5	4.7	8.6	-0.9	-2.9
Schizophrenia vs Biploar Disorder	2.4	3.1	6.3	2.5	-0.1
Height	2.4	46.3	65.0	-5.2	-8.1
Standing height	2.4	23.5	28.1	-4.4	-5.3
Irritability	2.4	4.1	6.2	-2.5	-1.4
Type 2 Diabetes (T2D) (2018)	2.3	4.3	8.3	-0.6	-2.9
Frequency of depressed mood in last 2 weeks	2.3	3.3	4.3	-1.5	-2.1
Eye problems/disorders: Diabetes related eye disease	2.3	2.5	2.6	-1.6	-1.6
Supplements: Glucosamine	2.3	3.0	5.3	-2.3	-0.9
Wears glasses or contact lenses	2.3	2.6	3.1	-1.8	-1.5
Eye problems/disorders: Glaucoma	2.3	2.7	3.2	1.8	1.5
Number of live births	2.2	3.2	3.4	1.8	1.7
Ever unenthusiastic/disinterested for a whole week	2.1	2.5	3.7	-1.9	-1.1
Average weekly champagne plus white wine intake	2.1	2.8	3.8	-1.4	-2.0
Chest pain or discomfort	2.0	2.8	5.7	-0.2	-2.4
Pain experienced in last month	2.0	3.4	4.6	1.4	2.1
Major Depression (MDD)	1.9	2.3	4.5	-0.2	-2.1
Osteoporosis (self-reported)	1.9	2.4	4.7	-0.1	-2.2
Miserableness	1.9	3.3	3.4	-1.8	-1.8
Diabetes (self-reported)	1.8	2.8	4.7	-0.9	-2.2
Medication: Paracetamol	1.8	2.9	5.8	-0.3	-2.4
Medication: Blood pressure	1.8	3.2	5.1	-1.2	-2.2
Medication: Aspirin	1.8	2.4	4.5	-0.5	-2.1
Qualifications: nursing, teaching	1.8	2.9	5.4	0.6	2.3
Hearing difficulty/problems: Yes	1.7	2.6	4.6	2.1	0.8
Frequency of tenseness / restlessness in last 2 weeks	1.7	2.7	5.3	-0.3	-2.3
Prospective memory result	1.7	2.1	4.2	-0.2	-2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	1.7	2.6	3.6	-1.3	-1.9
Medication: Lisinopril	1.7	2.2	2.6	-1.4	-1.6
Ovarian Cancer	1.6	2.1	2.3	-1.3	-1.5
Neuroticism	1.6	3.8	6.0	-1.3	-2.4
Supplements: Zinc	1.6	1.8	2.8	-0.9	-1.7
Serious illness, injury or assault of a close relative in last 2 years	1.6	1.8	3.6	1.9	0.0
Shortness of breath walking on level ground	1.6	1.9	2.4	-1.2	-1.6
Medication: Ibuprofen	1.6	1.9	2.8	-0.9	-1.7
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	3.7	0.1	1.9
Diabetes diagnosed by doctor	1.6	2.6	4.3	-1.0	-2.1
Number of treatments/medications taken	1.5	2.7	5.4	0.1	-2.3
Happiness	1.5	1.8	3.5	-1.9	-0.3
Health satisfaction	1.5	1.9	2.1	-1.3	-1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.7	1.9	1.4	1.3
Pulse rate, automated reading	1.5	4.9	4.9	-2.2	-2.2
Medication: Paracetamol	1.5	2.3	4.3	-0.5	-2.1
Deep venous thrombosis (DVT) (self-reported)	1.5	2.0	2.3	-1.5	-1.3
Angina	1.4	1.8	2.9	-0.9	-1.7
Townsend deprivation index at recruitment	1.4	1.9	2.9	1.7	1.0
Average weekly fortified wine intake	1.4	1.7	2.4	0.9	1.6
Fluid intelligence score	1.4	3.0	3.0	-1.7	-1.7
Forced expiratory volume in 1-second (FEV1)	1.4	4.9	5.1	-2.3	-2.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.3	4.5	-2.0	-2.1
Blood clot in the leg (DVT)	1.4	1.8	1.9	-1.4	-1.3
Glaucoma (self-reported)	1.4	1.6	2.0	1.4	1.1
Angina (self-reported)	1.4	1.9	2.7	-1.0	-1.6
Medication: Allopurinol	1.4	1.9	2.9	-1.0	-1.7
Alcohol drinker status: Never	1.4	1.6	2.8	1.7	0.7
Bipolar Disorder (2018)	1.3	2.0	4.0	0.3	2.0
Primary Biliary Cirrhosis	1.3	1.9	3.0	1.7	0.9
Medication for hormone replacement therapy	1.3	1.4	2.2	1.5	0.8
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	1.9	-0.9	-1.4
Medication: Atenolol	1.3	1.6	2.4	0.9	-1.6
Financial difficulties in last 2 years	1.3	1.7	2.0	-1.4	-1.2
Pain all over the body in last month	1.3	1.4	2.1	-1.5	-0.8
Worrier / anxious feelings	1.3	2.5	2.9	-1.5	-1.7
Medication for cholesterol, blood pressure or diabetes	1.3	2.1	2.9	1.2	1.7
Medication: Omeprazole	1.3	1.5	2.8	-1.7	-0.5
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	3.1	0.0	1.8
High cholesterol (Self-reported)	1.3	2.3	2.4	-1.6	-1.5
Number of operations (self-reported)	1.3	1.9	2.0	-1.3	-1.4
Age started oral contraceptive pill	1.3	1.6	1.9	-1.4	-1.1
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	2.4	-1.6	-0.9
Rheumatoid Arthritis	1.2	1.6	3.1	-1.8	-0.3
Medication: Co-codamol	1.2	1.3	2.4	-0.5	-1.6
Impedance of leg (left)	1.2	5.8	8.1	-2.8	-1.9
Waist circumference	1.2	4.5	6.9	-1.5	-2.6
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	2.7	-1.6	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	2.6	-1.6	0.6
Illnesses of father: Heart disease	1.2	1.6	2.9	-0.6	-1.7
Medication: Aspirin	1.2	1.6	3.2	0.1	-1.8
Ever taken oral contraceptive pill	1.2	1.3	2.6	-1.6	0.0
Severe depression (siblings)	1.1	1.3	2.0	-0.7	-1.4
Age when periods started (menarche)	1.1	2.7	3.3	-1.4	-1.8
Medication: Levothyroxine sodium	1.1	1.9	3.5	-0.6	-1.9
Trunk fat mass	1.1	4.6	7.1	-1.4	-2.7
Forced vital capacity (FVC), Best measure	1.1	3.9	5.1	-2.3	-1.6
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	1.6	-0.9	-1.3
Commuting to job workplace: Walk	1.1	1.2	1.3	1.0	1.1
Mineral and other dietary supplements	1.1	1.5	1.6	1.3	1.2
Type 2 Diabetes (T2D) (2012)	1.0	1.1	2.0	-0.5	-1.4
Cardiovascular Disease	1.0	3.4	6.9	0.1	-2.6
Sitting height	1.0	7.2	8.8	-3.0	-2.4
Forced vital capacity (FVC)	1.0	3.8	5.5	-2.3	-1.5
Medication: Simvastatin	1.0	1.5	2.9	-0.2	-1.7
Exposure to tobacco smoke at home	1.0	1.2	1.9	-1.4	-0.7
Arm fat-free mass (right)	1.0	5.0	6.1	-2.0	-2.5
Worry too long after embarrassment	1.0	1.7	3.3	-0.2	-1.8
Supplements: Vitamin C	1.0	1.1	1.3	-1.0	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.2	3.2	-1.8	-1.1
Eye problems/disorders: Cataract	1.0	1.2	2.2	-0.5	-1.5
Osteoarthritis (self-reported)	1.0	1.3	2.3	0.7	1.5
Commuting to job workplace: Public transport	1.0	1.2	2.0	-1.4	-0.7
Illnesses of father: High blood pressure	1.0	1.2	2.1	1.4	0.6
Ever depressed for a whole week	1.0	1.2	2.3	-1.5	-0.4
Myopia	1.0	1.4	2.4	-1.6	0.7
Age at First Birth	0.9	1.3	2.0	0.7	1.4
Impedance of leg (right)	0.9	4.4	6.8	-2.6	-1.4
Multivitamins +/- minerals	0.9	1.1	1.2	1.1	1.0
Ever highly irritable/argumentative for 2 days	0.9	1.1	1.9	-1.4	-0.5
Loud music exposure frequency	0.9	1.0	1.7	0.5	1.3
High blood pressure (siblings)	0.9	1.3	1.6	1.0	1.3
Exposure to tobacco smoke outside home	0.9	1.2	1.9	-1.4	-0.7
Eye problems/disorders: None of the above	0.9	1.0	1.4	-0.8	1.2
Arm predicted mass (right)	0.9	4.7	6.0	-1.8	-2.5
Handedness (chirality/laterality): Left-handed	0.9	1.1	2.0	0.5	1.4
Back pain experienced in last month	0.9	1.3	1.8	0.9	-1.3
Diastolic blood pressure, automated reading	0.9	2.9	5.8	-0.3	-2.4
Supplements: Calcium	0.9	0.9	1.6	-0.5	-1.3
Number of incorrect matches in round	0.8	1.4	1.4	1.1	1.2
Had other major operations	0.8	1.0	1.3	-0.8	-1.1
Qualifications: None of the above	0.8	1.8	3.2	0.6	-1.8
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	1.6	-1.3	-0.8
Father’s age at death	0.8	1.1	1.5	-1.2	-0.8
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	2.1	0.0	-1.4
Medication: Cholesterol lowering	0.8	1.2	1.4	-1.2	-1.1
Gout (self-reported)	0.8	1.1	1.6	-1.2	-0.8
Comparative body size at age 10	0.8	2.3	3.5	1.1	1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	1.6	-1.3	0.5
Impedance of whole body	0.8	4.0	4.3	-1.9	-2.1
Reaction Time	0.7	1.3	1.9	1.4	0.9
Verbal and Numeric Reasoning (VNR)	0.7	1.8	2.0	-1.3	-1.4
HbA1C	0.7	0.7	1.3	1.2	0.4
Lupus	0.7	1.0	2.0	-0.1	-1.4
Ulcerative Colitis	0.7	1.0	2.0	-1.4	0.2
Trunk fat percentage	0.7	2.9	4.9	-0.9	-2.2
Serious illness, injury or assault to yourself	0.7	0.9	1.7	-0.2	-1.3
Weight	0.7	3.6	5.4	-1.4	-2.3
Pulse wave Arterial Stiffness index	0.7	0.9	1.5	-1.2	-0.4
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	1.5	1.2	0.6
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	2.5	-0.4	-1.6
Pulse wave peak to peak time	0.7	0.8	1.3	1.1	0.5
Emphysema/chronic bronchitis	0.7	0.8	1.1	0.8	-1.0
Whole body fat mass	0.7	3.0	5.1	-1.0	-2.2
Hypertension (Self-reported)	0.7	1.9	3.0	0.9	-1.7
Friendships satisfaction	0.7	0.9	1.8	-0.1	1.4
Worry (Nagel 2018)	0.6	1.2	2.3	-0.4	-1.5
Ulcerative Colitis (UC)	0.6	1.1	2.1	-1.4	0.1
Schizophrenia (2014)	0.6	1.4	2.8	1.7	-0.0
Allergy or Eczema	0.6	1.5	1.5	1.2	1.2
Systolic blood pressure, automated reading	0.6	1.8	3.2	0.7	-1.8
Qualifications: CSEs or equivalent	0.6	0.8	1.0	1.0	0.8
High blood pressure	0.6	1.7	2.8	1.7	-0.8
Stomach or abdominal pain in last month	0.6	0.7	1.3	1.2	0.4
Had menopause	0.6	0.7	1.4	1.2	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	1.8	-0.2	-1.4
Pulse wave reflection index	0.6	0.8	1.4	-0.4	1.2
Medication: Amlodipine	0.6	0.8	1.3	1.1	0.6
Age at first live birth	0.6	1.1	1.9	-1.4	-0.5
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.0	-1.0	-0.6
Migraine (self-reported)	0.6	0.8	1.3	1.1	-0.5
Had major operations	0.6	0.7	1.3	-1.1	-0.4
Hearing aid user	0.6	0.7	1.1	0.5	-1.1
Cholesterol lowering medication	0.6	0.9	1.6	0.4	-1.3
Heart disease (siblings)	0.6	0.7	1.2	1.1	0.4
Alcohol drinker status: Previous	0.6	0.6	1.2	-1.1	-0.4
Pack years of smoking	0.6	0.9	1.4	0.6	-1.2
Bipolar Disorder or Schizophrenia	0.5	1.1	1.9	0.6	1.4
Bipolar Disorder (2011)	0.5	0.5	0.9	-0.9	0.4
Systolic Blood Pressure	0.5	2.5	2.9	1.7	-1.4
Respiratory disease	0.5	1.1	2.2	0.4	1.5
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.1	1.1	0.4
Ever had hysterectomy (womb removed)	0.5	0.6	1.2	-0.0	1.1
Alcohol usually taken with meals	0.5	0.8	0.9	0.9	-0.9
Trunk fat-free mass	0.5	2.8	3.5	-1.4	-1.9
Alcohol intake versus 10 years previously	0.5	0.7	1.3	-0.3	1.1
Lung cancer (father)	0.5	0.6	1.0	0.5	-1.0
Trunk predicted mass	0.5	2.7	3.5	-1.4	-1.9
Body fat percentage	0.5	1.9	3.3	-0.7	-1.8
Number of full sisters	0.5	0.6	1.3	0.1	1.1
Suffer from ‘nerves’	0.5	0.8	1.0	0.7	-1.0
Age at last live birth	0.5	0.7	1.3	-1.1	0.4
Arm fat mass (left)	0.5	2.1	3.7	-0.6	-1.9
Number of self-reported non-cancer illnesses	0.5	0.9	1.7	0.4	-1.3
Arm fat-free mass (left)	0.5	2.8	3.3	-1.5	-1.8
Unable to work because of sickness or disability	0.5	0.7	1.0	1.0	-0.6
Vascular/heart problems diagnosed by doctor	0.5	1.3	1.6	-1.3	1.0
Arm predicted mass (left)	0.5	2.4	3.3	-1.2	-1.8
Pack years adult smoking proportion	0.4	0.6	0.9	0.6	-0.9
Medication: Ramipril	0.4	0.5	0.6	-0.6	0.8
Illnesses of siblings	0.4	0.6	1.1	-1.1	-0.2
Medication: Lansoprazole	0.4	0.4	0.5	0.7	0.6
Impedance of arm (left)	0.4	2.0	3.7	-0.5	-1.9
Tense / ‘highly strung’	0.4	0.6	1.2	-0.2	-1.1
Overall health rating	0.4	0.9	1.8	-0.3	-1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	1.1	-0.7	-1.1
Medication: Atorvastatin	0.4	0.5	0.8	-0.9	-0.5
Basal metabolic rate	0.4	2.4	3.6	-1.1	-1.9
Commuting to job workplace: Cycle	0.4	0.5	1.0	1.0	-0.0
Leg fat mass (left)	0.4	1.6	2.5	-0.8	-1.6
Alzheimer’s Disease (in mother)	0.3	0.3	0.4	0.7	0.5
Irritable Bowel Disease (IBD)	0.3	0.7	1.3	-1.1	0.4
Triglycerides	0.3	0.5	0.8	-0.9	-0.5
Chronotype (morning person)	0.3	0.7	1.2	0.4	-1.1
Hair/balding pattern: Pattern 3	0.3	0.4	0.6	0.8	0.4
Depression (self-reported)	0.3	0.4	0.7	0.2	-0.8
Arm fat mass (right)	0.3	1.1	2.2	-0.1	-1.5
Birth weight of first child	0.3	0.6	0.6	-0.8	-0.8
Birth weight	0.3	0.7	1.3	0.2	-1.2
Leg fat percentage (right)	0.3	0.9	1.3	-0.8	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	0.6	0.4	-0.8
Wheeze or whistling in the chest in last year	0.3	0.5	1.0	-0.4	-1.0
Leg fat mass (right)	0.3	1.2	1.7	-0.8	-1.3
Whole body fat-free mass	0.3	1.8	2.8	-0.9	-1.7
Whole body water mass	0.3	1.7	2.7	-0.9	-1.6
Medication: Blood pressure	0.3	0.6	1.2	1.1	0.2
Leg fat percentage (left)	0.3	1.3	1.9	-0.8	-1.4
Alzheimer’s Disease (in father)	0.2	0.2	0.2	-0.4	0.4
LDL Cholesterol	0.2	0.2	0.4	0.6	-0.3
Blood Red Count	0.2	2.0	2.8	1.1	-1.7
Lung FEV1/FVC ratio	0.2	1.0	1.8	-0.5	-1.3
Tanning	0.2	1.9	3.6	-0.4	-1.9
Average weekly spirits intake	0.2	0.2	0.4	0.2	0.6
Sensitivity / hurt feelings	0.2	0.4	0.8	-0.0	-0.9
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.4	0.0	-0.7
Vitamin and mineral supplements	0.2	0.2	0.4	-0.7	0.2
Diabetes (father)	0.2	0.2	0.4	-0.2	-0.7
Current tobacco smoking	0.2	0.3	0.6	0.3	0.8
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.3	-0.5	-0.3
High blood pressure (mother)	0.2	0.3	0.5	-0.2	-0.7
Past tobacco smoking	0.2	0.3	0.6	0.8	0.3
Hair/balding pattern: Pattern 2	0.2	0.2	0.4	-0.6	0.3
Allergy	0.2	0.5	0.6	-0.8	-0.6
Time employed in main current job	0.2	0.2	0.4	0.3	-0.6
Falls in the last year	0.2	0.3	0.4	0.4	-0.6
Asthma	0.2	0.3	0.3	-0.5	0.6
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.4	0.6	0.4
Number of children fathered	0.2	0.2	0.4	-0.3	-0.6
Medication: Seretide 50 evohaler	0.2	0.2	0.3	-0.6	0.3
Alcohol intake frequency.	0.2	0.4	0.6	0.8	0.5
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.4	-0.0	-0.6
Illnesses of siblings: Diabetes	0.2	0.3	0.5	0.1	-0.7
Arm fat percentage (left)	0.2	0.9	1.8	0.2	-1.4
Average weekly red wine intake	0.2	0.3	0.6	0.8	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.5	-0.7	0.3
Medication for cholesterol	0.2	0.2	0.4	-0.6	0.4
Asthma (self-reported)	0.2	0.4	0.6	-0.5	0.8
Illnesses of father: None of the above (group 1)	0.2	0.2	0.5	0.0	0.7
Smoking status: Current	0.2	0.4	0.6	0.3	0.8
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.3	-0.5	-0.5
Medication: Bendroflumethiazide	0.2	0.3	0.4	0.6	-0.4
Schizophrenia (2018)	0.1	0.2	0.3	0.6	0.2
Alzheimer’s Disease (including proxy)	0.1	0.1	0.3	0.0	0.5
Crohns Disease (2017)	0.1	0.3	0.5	-0.7	-0.2
Prostate Cancer	0.1	0.1	0.2	-0.4	-0.1
Coronary Artery Disease (CAD)	0.1	0.1	0.2	0.2	0.4
Crohns Disease (2012)	0.1	0.1	0.1	-0.3	-0.3
Mean Putamen Volume	0.1	0.1	0.1	-0.3	0.1
Fasting Glucose	0.1	0.1	0.2	-0.4	-0.2
HDL Cholesterol	0.1	0.2	0.2	-0.4	-0.4
Blood White Count	0.1	0.6	0.6	0.8	-0.7
Hypothyroidism (self reported)	0.1	0.2	0.3	-0.5	-0.2
Hair Pigment	0.1	2.1	4.3	-2.1	-0.0
Relative age of first facial hair	0.1	0.3	0.4	-0.7	-0.3
Medication: Metformin	0.1	0.1	0.3	-0.0	-0.5
Leg fat-free mass (left)	0.1	0.6	1.1	-0.1	-1.1
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.4	0.6	0.4
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.1	-0.4	0.3
Chronic bronchitis/emphysema (father)	0.1	0.1	0.2	0.0	-0.5
Leg predicted mass (left)	0.1	0.5	1.0	-0.0	-1.0
Impedance of arm (right)	0.1	0.3	0.5	0.1	-0.7
Arm fat percentage (right)	0.1	0.5	0.5	0.7	-0.7
Hip circumference	0.1	0.3	0.6	0.8	-0.0
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.4	-0.3	0.6
Mouth/teeth dental problems: Dentures	0.1	0.2	0.3	-0.5	-0.3
Illnesses of mother	0.1	0.2	0.4	0.1	0.6
Hair/balding pattern: Pattern 4	0.1	0.2	0.3	-0.5	-0.5
Headache pain in last month	0.1	0.1	0.2	-0.0	-0.4
Leg pain on walking	0.1	0.1	0.2	-0.5	-0.3
Knee pain experienced in last month	0.1	0.1	0.2	0.5	-0.1
Smoking status: Previous	0.1	0.2	0.4	-0.6	-0.3
Leg fat-free mass (right)	0.1	0.6	1.1	-0.0	-1.1
Long-standing illness, disability or infirmity	0.1	0.2	0.2	-0.5	-0.5
Leg predicted mass (right)	0.1	0.6	1.2	-0.0	-1.1
Mother’s age at death	0.1	0.1	0.1	-0.4	-0.2
Financial situation satisfaction	0.1	0.1	0.1	0.4	0.3
Ever smoked	0.1	0.2	0.2	-0.4	-0.4
Average weekly beer plus cider intake	0.1	0.2	0.3	-0.1	0.6
Intelligence (Savage-Jansen 2018)	0.0	0.0	0.0	0.0	0.1
Breast Cancer	0.0	0.0	0.0	-0.1	-0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.1	-0.0	0.3
Blood Eosinophil Count	0.0	0.2	0.3	-0.5	-0.3
Blood Platelet Count	0.0	0.4	0.9	0.1	-0.9
BMI	0.0	0.0	0.0	0.0	0.2
Smoking Status	0.0	0.1	0.1	0.3	-0.2
Lung FVC	0.0	0.2	0.4	-0.6	0.2
Relative age voice broke	0.0	0.0	0.0	-0.1	0.0
Body mass index (BMI)	0.0	0.2	0.4	0.6	-0.0
Mouth/teeth dental problems	0.0	0.0	0.0	0.2	-0.0
Heart attack	0.0	0.0	0.1	-0.1	-0.2
Noisy workplace	0.0	0.0	0.0	-0.1	0.2
Length of working week for main job	0.0	0.0	0.0	0.2	0.0
Peak expiratory flow (PEF)	0.0	0.1	0.1	-0.3	0.1
Medication: Ventolin 100micrograms inhaler	0.0	0.0	0.0	-0.1	-0.2
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.0	0.2	-0.2
Qualifications: College or University degree	0.0	0.1	0.2	0.4	0.0
Mean time to correctly identify matches	0.0	0.1	0.1	0.3	-0.2
Family relationship satisfaction	0.0	0.0	0.0	-0.1	0.2
Medication: Gliclazide	0.0	0.0	0.0	0.0	-0.1
Supplements: Fish oil (including cod liver oil)	0.0	0.1	0.1	-0.0	-0.3
Risk taking	0.0	0.0	0.1	0.1	0.2
Heart attack/myocardial infarction (self-reported)	0.0	0.0	0.0	0.0	-0.1

Hub : Genes

C7orf58

Models

Trait associations