Best TWAS P=1.43e-08 · Best GWAS P=2.88e-15 conditioned to 1.45e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | VPS13B | 0.21 | 0.09 | enet | 17 | 0.07 | 3.1e-06 | 7.2 | -5.2 | 1.6e-07 | -0.90 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | VPS13B | 0.14 | 0.04 | enet | 11 | 0.04 | 2.1e-03 | 7.2 | -5.7 | 1.4e-08 | -0.94 | 0.02 | 0.96 | TRUE |
| 3 | GTEx | Testis | COX6C | 0.18 | 0.06 | lasso | 4 | 0.08 | 3.1e-04 | 3.9 | 5.3 | 1.2e-07 | 0.92 | 0.01 | 0.97 | FALSE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | COX6C | 0.08 | 0.03 | blup | 31 | 0.04 | 2.3e-02 | 3.6 | -5.2 | 2.4e-07 | -0.88 | 0.02 | 0.48 | FALSE |