Best TWAS P=1.6e-64 · Best GWAS P=3.25e-85 conditioned to 1.58e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | CADM1 | 0.18 | 0.13 | lasso | 1 | 0.12 | 7.9e-07 | -12 | 12 | 6.2e-33 | 0.00 | 0.82 | 0.01 | TRUE |
| 2 | GTEx | Thyroid | CADM1 | 0.55 | 0.53 | lasso | 3 | 0.53 | 2.9e-47 | 17 | -17 | 1.6e-64 | -0.82 | 1.00 | 0.00 | TRUE |
| 3 | METSIM | Adipose | CADM1 | 0.08 | 0.00 | enet | 38 | 0.02 | 8.3e-04 | 13 | 13 | 2.1e-37 | 0.31 | 0.13 | 0.28 | TRUE |
| 4 | YFS | Blood | CADM1 | 0.11 | 0.11 | bslmm | 631 | 0.12 | 1.1e-35 | 20 | -17 | 3.0e-64 | -0.94 | 0.00 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | CADM1 | 0.10 | 0.05 | blup | 191 | 0.09 | 2.7e-09 | -16 | -12 | 1.6e-35 | -0.71 | 0.19 | 0.81 | TRUE |