Best TWAS P=2.67e-16 · Best GWAS P=3.91e-16 conditioned to 0.594
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SMAD9 | 0.06 | 0.02 | enet | 9 | 0.03 | 5.2e-07 | -4.4 | -6.2 | 5.2e-10 | -0.55 | 0.30 | 0.58 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SMAD9 | 0.08 | 0.03 | enet | 6 | 0.05 | 2.9e-06 | -4.4 | -7.0 | 2.3e-12 | -0.66 | 0.17 | 0.81 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SMAD9 | 0.15 | 0.09 | lasso | 5 | 0.10 | 7.0e-11 | 6.9 | -7.1 | 1.0e-12 | -0.93 | 0.00 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | SMAD9 | 0.29 | 0.08 | blup | 84 | 0.11 | 7.6e-05 | 8.1 | 8.2 | 2.7e-16 | 0.77 | 0.00 | 0.98 | TRUE |