[Hub]/) : Traits : Heel T-Score : ← →

chr13:41,335,816-44,380,753

Best TWAS P=3.94e-32 · Best GWAS P=9.37e-152 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	AKAP11	0.16	0.20	lasso	4	0.19	3.6e-23	-7.6	7.7	1.5e-14	-0.42	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	DNAJC15	0.60	0.72	lasso	2	0.72	1.6e-125	-5.5	5.5	4.6e-08	0.00	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	DNAJC15	0.45	0.35	lasso	3	0.39	2.2e-33	-5.5	5.2	1.5e-07	0.02	1.00	0.00	FALSE
4	GTEx	Adrenal Gland	RGCC	0.21	0.00	lasso	5	0.02	6.7e-02	-7.8	7.5	8.4e-14	-0.04	0.01	0.82	TRUE
5	GTEx	Adrenal Gland	DNAJC15	0.45	0.53	lasso	3	0.52	1.2e-21	-5.5	5.4	5.3e-08	0.00	1.00	0.00	FALSE
6	GTEx	Artery Aorta	AKAP11	0.26	0.09	lasso	11	0.11	7.7e-07	-6.3	6.5	8.1e-11	-0.34	0.58	0.07	FALSE
7	GTEx	Artery Aorta	DNAJC15	0.59	0.57	lasso	7	0.58	2.4e-38	-5.5	5.2	2.0e-07	0.00	1.00	0.00	FALSE
8	GTEx	Artery Coronary	DNAJC15	0.47	0.45	lasso	4	0.45	1.2e-16	-5.5	5.4	7.2e-08	0.01	1.00	0.00	FALSE
9	GTEx	Artery Tibial	AKAP11	0.17	0.11	lasso	4	0.14	4.3e-11	-8.5	8.5	1.3e-17	-0.40	1.00	0.00	FALSE
10	GTEx	Brain Cerebellar Hemisphere	AKAP11	0.21	0.20	lasso	6	0.19	1.6e-05	-8.3	8.5	2.7e-17	-0.42	0.24	0.35	FALSE
11	GTEx	Brain Cerebellum	AKAP11	0.30	0.29	enet	15	0.30	2.1e-09	-7.6	8.9	7.2e-19	-0.45	0.99	0.00	TRUE
12	GTEx	Brain Cerebellum	DNAJC15	0.52	0.42	enet	6	0.46	3.4e-15	-5.5	5.1	3.1e-07	0.01	1.00	0.00	FALSE
13	GTEx	Brain Hippocampus	DNAJC15	0.54	0.37	lasso	7	0.41	7.8e-11	-5.5	5.2	2.4e-07	0.01	0.96	0.00	FALSE
14	GTEx	Brain Hypothalamus	DNAJC15	0.31	0.29	lasso	3	0.23	3.9e-06	-5.1	5.1	2.8e-07	0.01	0.72	0.02	FALSE
15	GTEx	Brain Nucleus accumbens basal ganglia	DNAJC15	0.46	0.32	lasso	8	0.37	6.8e-11	-5.5	5.3	1.2e-07	0.00	0.98	0.00	FALSE
16	GTEx	Breast Mammary Tissue (Male)	DNAJC15	0.61	0.51	lasso	5	0.49	5.0e-13	-5.5	5.3	1.1e-07	0.00	0.98	0.00	FALSE
17	GTEx	Cells EBV-transformed lymphocytes	DNAJC15	0.53	0.52	lasso	5	0.50	1.1e-18	-5.5	5.4	5.5e-08	0.01	1.00	0.00	FALSE
18	GTEx	Cells Transformed fibroblasts	DNAJC15	0.45	0.52	lasso	6	0.53	2.3e-46	-5.5	5.6	2.2e-08	0.00	1.00	0.00	FALSE
19	GTEx	Colon Sigmoid	AKAP11	0.21	0.06	lasso	4	0.09	4.0e-04	3.3	5.8	6.2e-09	-0.52	0.13	0.17	FALSE
20	GTEx	Colon Sigmoid	RGCC	0.21	-0.01	enet	26	0.02	6.5e-02	4.4	7.4	1.0e-13	-0.03	0.05	0.26	TRUE
21	GTEx	Colon Sigmoid	DNAJC15	0.71	0.60	lasso	8	0.61	1.3e-26	-5.5	5.2	2.4e-07	0.01	1.00	0.00	FALSE
22	GTEx	Colon Transverse	DNAJC15	0.46	0.44	lasso	5	0.43	6.3e-22	-5.5	5.4	6.4e-08	0.00	1.00	0.00	FALSE
23	GTEx	Esophagus Gastroesophageal Junction	AKAP11	0.17	-0.01	enet	21	-0.01	7.0e-01	-8.3	5.6	2.5e-08	-0.42	0.10	0.11	TRUE
24	GTEx	Esophagus Mucosa	AKAP11	0.25	0.18	lasso	9	0.17	1.6e-11	-7.9	9.5	2.2e-21	-0.53	1.00	0.00	FALSE
25	GTEx	Esophagus Mucosa	DNAJC15	0.56	0.54	lasso	5	0.57	1.1e-45	-5.5	5.4	7.1e-08	0.00	1.00	0.00	FALSE
26	GTEx	Esophagus Muscularis	AKAP11	0.23	0.19	lasso	4	0.19	2.1e-11	-7.7	7.9	2.5e-15	-0.43	1.00	0.00	FALSE
27	GTEx	Esophagus Muscularis	DNAJC15	0.43	0.44	lasso	8	0.46	4.5e-31	-5.5	5.3	9.1e-08	0.01	1.00	0.00	FALSE
28	GTEx	Heart Left Ventricle	DNAJC15	0.32	0.30	lasso	7	0.31	6.4e-17	-5.5	5.1	2.8e-07	0.01	1.00	0.00	FALSE
29	GTEx	Liver	DNAJC15	0.64	0.48	lasso	10	0.53	2.6e-17	-5.5	5.3	1.3e-07	0.01	1.00	0.00	FALSE
30	GTEx	Lung	AKAP11	0.08	0.00	lasso	2	0.02	1.8e-02	6.9	9.0	2.9e-19	-0.13	0.07	0.15	TRUE
31	GTEx	Lung	DNAJC15	0.47	0.60	lasso	3	0.60	2.5e-57	-5.5	5.5	4.6e-08	0.00	1.00	0.00	FALSE
32	GTEx	Muscle Skeletal	AKAP11	0.15	0.10	lasso	8	0.10	2.4e-10	-8.3	-7.6	4.0e-14	0.37	1.00	0.00	FALSE
33	GTEx	Nerve Tibial	AKAP11	0.12	0.00	enet	19	0.01	5.1e-02	11.1	9.3	1.1e-20	-0.37	0.36	0.04	TRUE
34	GTEx	Pancreas	DNAJC15	0.56	0.52	lasso	7	0.53	6.1e-26	-5.5	5.7	1.6e-08	0.01	1.00	0.00	FALSE
35	GTEx	Pituitary	DNAJC15	0.68	0.55	lasso	4	0.53	1.5e-15	-5.4	5.5	5.1e-08	0.00	1.00	0.00	FALSE
36	GTEx	Skin Not Sun Exposed Suprapubic	AKAP11	0.14	0.00	enet	32	0.00	4.1e-01	2.3	7.2	6.4e-13	-0.36	0.14	0.12	FALSE
37	GTEx	Skin Not Sun Exposed Suprapubic	DNAJC15	0.46	0.50	lasso	5	0.50	5.6e-31	-5.5	5.3	1.5e-07	0.00	1.00	0.00	FALSE
38	GTEx	Skin Sun Exposed Lower leg	AKAP11	0.06	0.05	lasso	3	0.04	4.6e-04	-8.3	7.8	5.4e-15	-0.40	0.82	0.03	FALSE
39	GTEx	Skin Sun Exposed Lower leg	RGCC	0.08	0.01	enet	18	0.03	1.5e-03	-3.5	5.7	1.1e-08	-0.03	0.16	0.04	FALSE
40	GTEx	Spleen	DNAJC15	0.71	0.56	enet	20	0.63	2.3e-20	-5.5	5.2	2.3e-07	0.00	1.00	0.00	FALSE
41	GTEx	Testis	AKAP11	0.15	0.03	enet	13	0.09	6.4e-05	12.2	11.6	7.1e-31	-0.43	0.24	0.23	TRUE
42	GTEx	Testis	DNAJC15	0.43	0.38	lasso	3	0.36	1.3e-16	-5.5	5.2	1.6e-07	0.00	1.00	0.00	FALSE
43	GTEx	Thyroid	DNAJC15	0.43	0.35	lasso	9	0.35	5.6e-28	-5.5	5.6	2.5e-08	0.00	1.00	0.00	FALSE
44	GTEx	Whole Blood	DNAJC15	0.16	0.15	lasso	4	0.14	4.2e-13	-5.5	5.4	8.1e-08	0.01	1.00	0.00	FALSE
45	METSIM	Adipose	AKAP11	0.03	0.01	lasso	5	0.01	3.7e-02	-7.6	7.2	5.4e-13	-0.39	0.35	0.12	FALSE
46	METSIM	Adipose	DNAJC15	0.28	0.32	lasso	5	0.32	6.9e-49	-5.4	5.2	1.7e-07	0.00	1.00	0.00	FALSE
47	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	DNAJC15	0.09	0.07	lasso	2	0.06	1.4e-05	-5.4	5.5	4.6e-08	0.00	0.00	1.00	FALSE
48	The Cancer Genome Atlas	Breast Invasive Carcinoma	AKAP11	0.05	0.01	enet	18	0.03	3.9e-06	-7.9	5.2	2.3e-07	-0.28	0.15	0.03	TRUE
49	The Cancer Genome Atlas	Breast Invasive Carcinoma	DNAJC15	0.18	0.28	enet	13	0.29	1.3e-60	-5.5	5.5	4.1e-08	0.00	0.00	1.00	FALSE
50	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	DNAJC15	0.08	0.10	lasso	1	0.07	2.0e-04	-5.5	5.5	3.3e-08	0.00	0.01	0.99	FALSE
51	The Cancer Genome Atlas	Colon Adenocarcinoma	TNFSF11	0.14	0.01	blup	60	0.03	4.5e-03	-5.0	5.9	3.3e-09	-0.20	0.02	0.06	FALSE
52	The Cancer Genome Atlas	Glioblastoma Multiforme	DNAJC15	0.40	0.45	lasso	8	0.44	1.0e-14	-5.5	5.6	2.3e-08	0.00	0.01	0.99	FALSE
53	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DNAJC15	0.24	0.29	lasso	7	0.29	2.4e-33	-5.5	5.4	6.4e-08	0.01	0.00	1.00	FALSE
54	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DNAJC15	0.32	0.37	lasso	4	0.39	1.8e-46	-5.4	5.4	5.7e-08	0.00	0.00	1.00	FALSE
55	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DNAJC15	0.38	0.21	blup	92	0.31	2.3e-18	-5.5	5.4	7.9e-08	0.00	0.00	1.00	FALSE
56	The Cancer Genome Atlas	Brain Lower Grade Glioma	AKAP11	0.03	0.00	blup	85	0.02	5.0e-03	-7.9	8.5	1.6e-17	-0.41	0.03	0.03	FALSE
57	The Cancer Genome Atlas	Brain Lower Grade Glioma	DNAJC15	0.32	0.38	lasso	5	0.46	8.8e-58	-5.5	5.3	9.5e-08	0.00	0.00	1.00	FALSE
58	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	DNAJC15	0.36	0.35	lasso	4	0.34	1.4e-16	-5.4	5.4	5.3e-08	0.00	0.00	1.00	FALSE
59	The Cancer Genome Atlas	Lung Adenocarcinoma	DNAJC15	0.24	0.27	enet	12	0.27	2.0e-31	-5.5	5.6	1.8e-08	0.00	0.00	1.00	FALSE
60	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	AKAP11	0.04	0.05	lasso	3	0.04	7.2e-06	-9.9	10.1	3.9e-24	-0.45	0.76	0.18	FALSE
61	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DNAJC15	0.19	0.24	lasso	3	0.24	1.3e-26	-5.4	5.5	4.3e-08	0.00	0.01	0.99	FALSE
62	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	AKAP11	0.04	0.00	blup	85	0.02	2.1e-02	-8.4	11.8	3.9e-32	-0.50	0.04	0.35	TRUE
63	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	DNAJC15	0.10	0.04	blup	92	0.04	7.8e-04	-5.4	5.4	5.8e-08	-0.01	0.01	0.94	FALSE
64	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DNAJC15	0.29	0.33	lasso	4	0.35	1.3e-15	-5.5	5.7	1.1e-08	0.01	0.01	0.99	FALSE
65	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	DNAJC15	0.32	0.28	lasso	7	0.31	4.5e-13	-5.5	5.5	4.3e-08	0.01	0.01	0.98	FALSE
66	The Cancer Genome Atlas	Prostate Adenocarcinoma	DNAJC15	0.17	0.21	lasso	4	0.21	4.0e-21	-5.5	5.6	2.6e-08	0.00	0.00	1.00	FALSE
67	The Cancer Genome Atlas	Rectum Adenocarcinoma	DNAJC15	0.38	0.28	enet	9	0.32	3.5e-08	-5.5	6.0	2.2e-09	0.00	0.01	0.98	TRUE
68	The Cancer Genome Atlas	Soft Tissue Sarcoma	DNAJC15	0.18	0.16	lasso	3	0.15	5.9e-09	-5.5	5.5	4.0e-08	0.01	0.00	1.00	FALSE
69	The Cancer Genome Atlas	Thyroid Carcinoma	AKAP11	0.07	0.09	lasso	3	0.08	3.7e-08	-7.6	7.6	3.3e-14	-0.41	1.00	0.00	FALSE
70	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	DNAJC15	0.16	0.06	blup	92	0.10	1.0e-03	-5.4	5.2	1.9e-07	0.00	0.02	0.88	FALSE