[Hub]/) : Traits : Heel T-Score :

chr13:31,078,511-34,048,051

Best TWAS P=5.97e-11 · Best GWAS P=1.68e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-298P3.4 0.09 0.01 lasso 7 0.00 1.9e-01 -5.9 -6.4 1.2e-10 0.86 0.07 0.84 FALSE
2 GTEx Artery Aorta N4BP2L2 0.13 0.10 lasso 3 0.09 1.1e-05 -6.5 -6.5 6.0e-11 0.99 0.01 0.99 TRUE
3 GTEx Breast Mammary Tissue B3GALTL 0.21 -0.01 enet 36 0.04 2.8e-03 -2.2 5.4 7.3e-08 -0.03 0.04 0.66 TRUE
4 GTEx Nerve Tibial RP11-298P3.4 0.06 0.01 enet 19 0.01 7.8e-02 -5.9 -5.5 5.1e-08 0.66 0.10 0.62 FALSE
5 GTEx Testis B3GALTL 0.29 0.15 lasso 6 0.18 2.6e-08 5.1 5.2 2.2e-07 0.03 0.02 0.98 FALSE
6 YFS Blood PDS5B 0.03 0.04 lasso 1 0.03 1.4e-11 -5.7 -5.7 1.0e-08 0.80 0.14 0.86 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma CG030 0.04 0.01 lasso 3 0.02 2.1e-04 -6.5 5.9 3.5e-09 -0.97 0.01 0.99 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma N4BP2L2 0.02 0.02 lasso 2 0.01 1.4e-03 -6.0 -6.0 2.2e-09 0.97 0.01 0.94 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma N4BP2L2 0.04 0.03 blup 69 0.02 9.4e-04 -6.5 -5.9 3.8e-09 0.97 0.01 0.97 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma N4BP2L2 0.10 0.10 lasso 4 0.11 5.2e-12 -6.5 -6.2 7.2e-10 0.97 0.01 0.99 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma N4BP2L2 0.03 0.02 lasso 4 0.02 2.8e-03 -6.0 -5.6 2.5e-08 0.88 0.01 0.95 FALSE
12 The Cancer Genome Atlas Lung Squamous Cell Carcinoma N4BP2L2 0.04 0.04 lasso 2 0.03 1.5e-04 -6.0 -6.1 1.1e-09 0.97 0.01 0.97 FALSE
13 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CG030 0.08 0.04 blup 38 0.04 1.4e-03 -6.7 5.5 3.0e-08 -0.94 0.00 0.91 FALSE
14 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CG030 0.12 0.02 blup 38 0.03 3.1e-02 -6.4 5.5 3.1e-08 -0.84 0.01 0.58 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma N4BP2L2 0.06 0.03 lasso 3 0.05 1.0e-05 3.6 -5.3 1.3e-07 0.81 0.02 0.98 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma N4BP2L2 0.12 0.14 enet 7 0.16 1.1e-15 -6.2 -6.3 2.5e-10 0.98 0.02 0.98 FALSE
17 The Cancer Genome Atlas Thyroid Carcinoma PDS5B 0.02 0.01 blup 78 0.02 1.2e-02 -6.2 5.9 3.9e-09 -0.91 0.01 0.89 FALSE