Best TWAS P=9.86e-08 · Best GWAS P=1.57e-22 conditioned to 2.75e-22
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | GPC6 | 0.19 | 0.16 | lasso | 5 | 0.14 | 4.8e-11 | -5.3 | -5.3 | 1.1e-07 | 0.01 | 1 | 0 | FALSE |
| 2 | The Cancer Genome Atlas | Thyroid Carcinoma | GPC6 | 0.26 | 0.24 | lasso | 5 | 0.24 | 3.1e-23 | -5.3 | -5.3 | 9.9e-08 | 0.01 | 1 | 0 | TRUE |