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chr13:49,409,343-53,914,953

Best TWAS P=4.51e-21 · Best GWAS P=3.74e-43 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	EBPL	0.34	0.16	bslmm	399	0.33	2.5e-41	0.38	5.3	8.9e-08	0.05	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	HNRNPA1L2	0.14	0.16	lasso	7	0.16	1.0e-18	-5.09	5.5	3.6e-08	0.00	0.40	0.60	FALSE
3	CommonMind	Brain Pre-frontal Cortex	SPRYD7	0.07	0.06	lasso	3	0.07	1.5e-08	2.91	5.2	2.3e-07	0.19	1.00	0.00	TRUE
4	CommonMind	Brain Pre-frontal Cortex	TRIM13	0.15	0.04	lasso	5	0.12	1.1e-14	-9.44	8.7	3.5e-18	0.25	1.00	0.00	FALSE
5	GTEx	Adipose Subcutaneous	HNRNPA1L2	0.06	0.05	lasso	4	0.03	2.2e-03	-5.85	5.2	1.6e-07	-0.01	0.02	0.98	FALSE
6	GTEx	Adipose Visceral Omentum	EBPL	0.27	0.03	enet	17	0.20	1.4e-10	-6.42	5.9	4.4e-09	0.10	0.76	0.15	FALSE
7	GTEx	Adipose Visceral Omentum	HNRNPA1L2	0.12	0.05	lasso	8	0.05	1.8e-03	-5.09	5.2	1.9e-07	0.00	0.01	0.96	FALSE
8	GTEx	Artery Aorta	EBPL	0.43	0.20	enet	78	0.28	8.1e-16	-6.07	6.7	1.8e-11	0.16	0.99	0.01	TRUE
9	GTEx	Artery Aorta	HNRNPA1L2	0.11	0.07	lasso	4	0.06	2.0e-04	-5.85	5.6	2.1e-08	-0.01	0.01	0.99	FALSE
10	GTEx	Artery Coronary	EBPL	0.48	0.03	enet	99	0.12	9.7e-05	-6.42	6.0	2.7e-09	0.07	0.17	0.44	FALSE
11	GTEx	Artery Tibial	HNRNPA1L2	0.09	0.07	lasso	5	0.08	4.6e-07	5.05	5.3	1.4e-07	-0.02	0.02	0.98	FALSE
12	GTEx	Brain Cerebellar Hemisphere	HNRNPA1L2	0.24	0.26	lasso	5	0.23	1.4e-06	-5.44	5.5	3.4e-08	0.00	0.09	0.81	FALSE
13	GTEx	Brain Cerebellum	EBPL	0.50	0.30	enet	23	0.36	1.8e-11	-6.42	5.7	1.2e-08	0.07	0.86	0.02	FALSE
14	GTEx	Brain Cortex	HNRNPA1L2	0.26	0.17	lasso	6	0.15	8.3e-05	-5.09	5.5	3.2e-08	0.00	0.02	0.97	FALSE
15	GTEx	Brain Frontal Cortex BA9	EBPL	0.50	0.20	enet	18	0.34	7.0e-10	0.38	5.2	1.8e-07	0.04	0.33	0.30	FALSE
16	GTEx	Brain Frontal Cortex BA9	HNRNPA1L2	0.31	0.36	enet	9	0.36	1.5e-10	-5.39	5.1	2.9e-07	-0.01	0.08	0.92	FALSE
17	GTEx	Brain Frontal Cortex BA9	MRPS31P4	0.32	0.27	lasso	6	0.26	1.9e-07	-5.09	5.2	2.6e-07	0.01	0.02	0.96	FALSE
18	GTEx	Brain Hypothalamus	HNRNPA1L2	0.20	0.10	lasso	5	0.12	1.0e-03	-6.14	6.1	1.0e-09	0.00	0.01	0.94	FALSE
19	GTEx	Brain Nucleus accumbens basal ganglia	EBPL	0.25	0.11	enet	21	0.11	7.9e-04	-6.06	7.2	4.8e-13	0.14	0.11	0.21	FALSE
20	GTEx	Brain Nucleus accumbens basal ganglia	HNRNPA1L2	0.21	0.02	enet	9	0.04	4.1e-02	-6.14	5.5	3.5e-08	0.01	0.01	0.94	FALSE
21	GTEx	Brain Putamen basal ganglia	DHRS12	0.25	0.11	lasso	4	0.04	3.5e-02	-5.28	5.7	1.4e-08	-0.03	0.05	0.24	FALSE
22	GTEx	Brain Putamen basal ganglia	EBPL	0.31	-0.01	enet	18	0.05	2.9e-02	-6.06	7.6	3.7e-14	0.10	0.04	0.42	FALSE
23	GTEx	Breast Mammary Tissue (Male)	MRPS31P4	0.14	-0.01	lasso	4	-0.01	7.0e-01	-5.40	5.1	2.8e-07	-0.01	0.03	0.52	FALSE
24	GTEx	Cells Transformed fibroblasts	HNRNPA1L2	0.09	0.11	lasso	3	0.09	4.5e-07	5.05	5.2	1.6e-07	-0.02	0.02	0.98	FALSE
25	GTEx	Colon Sigmoid	HNRNPA1L2	0.20	0.09	lasso	4	0.06	2.8e-03	-5.44	5.6	2.8e-08	-0.01	0.06	0.68	FALSE
26	GTEx	Colon Transverse	NEK3	0.08	0.10	lasso	2	0.10	1.6e-05	4.44	-5.2	1.8e-07	0.02	0.18	0.11	TRUE
27	GTEx	Esophagus Gastroesophageal Junction	EBPL	0.27	0.24	enet	14	0.26	4.6e-10	-6.11	6.2	5.3e-10	0.03	0.97	0.03	FALSE
28	GTEx	Esophagus Muscularis	HNRNPA1L2	0.11	0.16	lasso	2	0.13	3.7e-08	-5.44	5.5	4.4e-08	0.00	0.16	0.84	FALSE
29	GTEx	Heart Atrial Appendage	HNRNPA1L2	0.15	0.04	lasso	16	0.08	1.8e-04	2.45	5.7	1.4e-08	0.04	0.04	0.95	FALSE
30	GTEx	Nerve Tibial	WDFY2	0.24	0.13	lasso	11	0.11	2.2e-08	-6.16	-6.0	2.2e-09	-0.03	0.01	0.99	FALSE
31	GTEx	Nerve Tibial	DLEU2	0.11	0.05	lasso	3	0.02	7.8e-03	-9.53	-9.4	4.5e-21	-0.13	0.51	0.02	TRUE
32	GTEx	Pituitary	EBPL	0.44	0.32	enet	29	0.37	3.1e-10	-6.07	7.0	2.3e-12	-0.01	0.72	0.23	FALSE
33	GTEx	Skin Not Sun Exposed Suprapubic	EBPL	0.34	0.26	enet	12	0.30	4.0e-17	-6.07	6.1	1.1e-09	0.01	1.00	0.00	FALSE
34	GTEx	Skin Sun Exposed Lower leg	EBPL	0.28	0.21	lasso	5	0.20	2.5e-16	-6.12	6.5	7.9e-11	0.02	1.00	0.00	FALSE
35	GTEx	Skin Sun Exposed Lower leg	HNRNPA1L2	0.10	0.09	lasso	4	0.08	1.7e-07	5.05	5.2	2.2e-07	-0.02	0.24	0.76	FALSE
36	GTEx	Small Intestine Terminal Ileum	RCBTB1	0.29	0.12	lasso	4	0.10	3.4e-03	3.80	-5.6	2.5e-08	0.03	0.08	0.21	FALSE
37	GTEx	Testis	EBPL	0.33	0.17	lasso	6	0.24	8.4e-11	-6.03	7.2	6.9e-13	0.05	0.99	0.00	FALSE
38	GTEx	Thyroid	EBPL	0.36	0.14	enet	33	0.30	5.1e-23	-6.11	6.9	3.8e-12	0.10	1.00	0.00	TRUE
39	GTEx	Thyroid	HNRNPA1L2	0.11	0.15	lasso	3	0.14	1.6e-10	-5.44	5.5	4.3e-08	-0.01	0.12	0.88	FALSE
40	METSIM	Adipose	WDFY2	0.09	0.08	bslmm	500	0.08	7.2e-12	-5.94	-5.9	3.9e-09	-0.04	0.02	0.98	FALSE
41	NTR	Blood	DLEU7	0.07	0.02	enet	22	0.06	1.3e-19	2.32	9.3	1.6e-20	0.60	0.05	0.95	TRUE
42	NTR	Blood	WDFY2	0.04	0.03	enet	11	0.04	1.7e-11	-6.18	6.6	3.9e-11	0.02	0.01	0.99	TRUE
43	YFS	Blood	KPNA3	0.04	0.02	bslmm	427	0.02	1.4e-08	-2.52	-6.2	6.2e-10	-0.08	1.00	0.00	TRUE
44	The Cancer Genome Atlas	Breast Invasive Carcinoma	WDFY2	0.02	0.02	lasso	3	0.02	3.4e-04	-5.94	5.6	1.8e-08	0.03	0.02	0.95	FALSE
45	The Cancer Genome Atlas	Colon Adenocarcinoma	EBPL	0.20	0.04	blup	59	0.11	6.8e-07	1.79	5.2	1.8e-07	0.08	0.64	0.19	FALSE
46	The Cancer Genome Atlas	Colon Adenocarcinoma	SUGT1	0.09	0.05	lasso	2	0.05	9.0e-04	-5.09	-5.2	1.9e-07	0.00	0.02	0.87	FALSE
47	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	WDFY2	0.03	0.03	enet	8	0.02	2.3e-03	-6.18	5.5	4.5e-08	0.02	0.01	0.96	FALSE
48	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DLEU2	0.08	0.02	lasso	2	0.01	1.6e-02	2.65	-5.2	2.5e-07	0.02	0.12	0.26	FALSE
49	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EBPL	0.21	0.14	enet	15	0.19	3.6e-21	1.79	5.4	7.8e-08	0.10	1.00	0.00	FALSE
50	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NEK3	0.17	0.10	lasso	2	0.14	3.8e-15	4.44	-5.3	1.3e-07	-0.01	0.00	0.97	FALSE
51	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TPTE2P3	0.06	0.00	lasso	2	0.02	2.5e-03	-5.85	6.0	1.9e-09	0.03	0.00	0.60	FALSE
52	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EBPL	0.27	0.16	blup	59	0.22	1.0e-12	1.79	7.1	1.3e-12	0.06	0.30	0.69	TRUE
53	The Cancer Genome Atlas	Brain Lower Grade Glioma	SUGT1	0.04	0.03	lasso	3	0.03	3.3e-04	-5.09	-5.2	2.0e-07	0.01	0.02	0.93	FALSE
54	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	SUGT1	0.09	0.05	lasso	2	0.03	1.6e-02	-5.09	-5.3	1.0e-07	-0.01	0.01	0.89	FALSE
55	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DLEU2	0.03	0.01	blup	61	0.02	2.4e-03	-9.45	-9.0	2.4e-19	-0.12	0.01	0.97	FALSE
56	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	VPS36	0.11	0.06	lasso	3	0.08	4.1e-09	3.83	-5.5	3.9e-08	0.00	0.01	0.99	FALSE
57	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	NEK3	0.16	0.07	lasso	4	0.07	3.4e-05	-4.91	-5.3	1.2e-07	-0.01	0.00	0.97	FALSE
58	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	EBPL	0.21	0.09	enet	10	0.13	4.9e-06	-6.42	5.6	1.7e-08	0.08	0.00	0.99	FALSE
59	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	EBPL	0.28	0.18	blup	59	0.19	4.3e-08	-6.06	7.0	3.2e-12	0.07	0.01	0.99	FALSE
60	The Cancer Genome Atlas	Prostate Adenocarcinoma	EBPL	0.08	0.01	blup	59	0.04	6.4e-05	-6.06	7.7	1.7e-14	0.03	0.01	0.88	FALSE
61	The Cancer Genome Atlas	Prostate Adenocarcinoma	SUGT1	0.05	0.05	lasso	2	0.04	6.8e-05	-5.31	-5.3	1.1e-07	-0.01	0.05	0.70	TRUE
62	The Cancer Genome Atlas	Stomach Adenocarcinoma	EBPL	0.10	0.07	enet	7	0.08	2.8e-06	-6.42	5.8	5.8e-09	0.14	0.00	0.99	FALSE
63	The Cancer Genome Atlas	Thyroid Carcinoma	TRIM13	0.04	0.00	blup	26	0.02	8.5e-03	-9.51	6.8	7.2e-12	0.07	0.00	0.45	FALSE