[Hub]/) : Traits : Heel T-Score :

chr13:98,746,497-101,243,161

Best TWAS P=8.78e-70 · Best GWAS P=6.15e-70 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous DOCK9-AS2 0.20 0.16 lasso 9 0.20 1.4e-16 -9.9 -8.2 1.8e-16 -0.48 1.00 0.00 FALSE
2 GTEx Artery Aorta DOCK9-AS2 0.16 0.11 lasso 6 0.17 2.1e-09 -10.2 -10.5 5.7e-26 -0.49 1.00 0.00 FALSE
3 GTEx Artery Tibial DOCK9 0.09 0.02 lasso 3 0.03 1.2e-03 12.9 -13.7 6.3e-43 -0.63 0.06 0.83 FALSE
4 GTEx Artery Tibial DOCK9-AS2 0.16 0.14 lasso 14 0.17 1.5e-13 9.4 -10.9 9.1e-28 -0.47 1.00 0.00 FALSE
5 GTEx Brain Cerebellar Hemisphere DOCK9-AS2 0.20 0.01 lasso 5 -0.01 7.4e-01 8.3 -9.7 3.1e-22 -0.41 0.08 0.10 FALSE
6 GTEx Brain Cortex DOCK9-AS2 0.25 0.08 lasso 6 0.05 2.2e-02 9.3 -8.5 1.5e-17 -0.37 0.14 0.07 FALSE
7 GTEx Brain Putamen basal ganglia DOCK9-AS2 0.55 0.22 lasso 12 0.17 6.1e-05 9.4 -7.1 9.7e-13 -0.35 0.24 0.09 FALSE
8 GTEx Breast Mammary Tissue DOCK9-AS2 0.14 0.08 lasso 9 0.08 7.7e-05 10.2 -11.9 9.3e-33 -0.53 0.79 0.18 FALSE
9 GTEx Breast Mammary Tissue (Female) DOCK9-AS2 0.14 0.07 lasso 9 0.04 2.0e-02 12.0 -14.1 2.7e-45 -0.67 0.11 0.62 FALSE
10 GTEx Esophagus Gastroesophageal Junction DOCK9-AS2 0.11 0.02 lasso 6 0.05 4.9e-03 -9.1 -10.6 2.4e-26 -0.50 0.21 0.44 FALSE
11 GTEx Esophagus Mucosa DOCK9 0.18 0.09 lasso 5 0.13 6.9e-09 -9.2 -14.0 2.4e-44 -0.69 0.72 0.26 FALSE
12 GTEx Esophagus Mucosa CLYBL 0.15 0.07 lasso 5 0.11 1.6e-07 6.6 -5.5 5.1e-08 0.03 0.85 0.01 FALSE
13 GTEx Lung DOCK9-AS2 0.14 0.05 enet 6 0.04 3.1e-04 -7.9 -9.3 1.1e-20 -0.37 0.94 0.00 FALSE
14 GTEx Muscle Skeletal CLYBL 0.12 0.07 enet 37 0.11 1.3e-10 6.6 -6.0 1.7e-09 -0.04 0.98 0.00 FALSE
15 GTEx Muscle Skeletal DOCK9-AS2 0.22 0.24 lasso 8 0.21 7.8e-20 -9.1 -9.1 6.0e-20 -0.42 1.00 0.00 FALSE
16 GTEx Nerve Tibial DOCK9 0.17 0.17 lasso 1 0.16 4.1e-11 17.7 -17.7 8.8e-70 -1.00 0.00 1.00 TRUE
17 GTEx Nerve Tibial CLYBL 0.24 0.10 lasso 5 0.12 1.1e-08 6.6 -8.0 1.2e-15 0.01 0.96 0.01 TRUE
18 GTEx Nerve Tibial DOCK9-AS2 0.18 0.16 lasso 9 0.13 9.2e-10 9.3 -8.2 1.7e-16 -0.33 1.00 0.00 FALSE
19 GTEx Pancreas DOCK9-AS2 0.09 0.08 lasso 6 0.08 3.0e-04 -9.1 -11.8 2.7e-32 -0.56 0.26 0.26 FALSE
20 GTEx Skin Not Sun Exposed Suprapubic DOCK9-AS2 0.20 0.25 enet 17 0.22 3.1e-12 -7.9 -9.3 1.2e-20 -0.39 1.00 0.00 FALSE
21 GTEx Skin Sun Exposed Lower leg CLYBL 0.30 0.10 enet 41 0.13 8.8e-11 6.6 -6.6 4.1e-11 0.01 0.98 0.00 FALSE
22 GTEx Skin Sun Exposed Lower leg DOCK9-AS2 0.15 0.14 lasso 9 0.19 2.1e-15 10.2 -9.6 7.0e-22 -0.42 1.00 0.00 FALSE
23 GTEx Spleen DOCK9 0.34 0.11 enet 35 0.12 5.3e-04 12.9 12.4 2.0e-35 0.52 0.28 0.21 TRUE
24 GTEx Stomach DOCK9-AS2 0.07 0.08 lasso 1 0.05 2.0e-03 10.2 -10.2 2.1e-24 -0.48 0.29 0.04 FALSE
25 GTEx Thyroid DOCK9-AS2 0.17 0.16 lasso 6 0.17 3.0e-13 -9.7 -7.5 8.4e-14 -0.36 1.00 0.00 FALSE
26 The Cancer Genome Atlas Bladder Urothelial Carcinoma CLYBL 0.10 0.01 enet 7 0.04 3.8e-04 6.8 -7.1 9.2e-13 -0.04 0.28 0.02 FALSE
27 The Cancer Genome Atlas Bladder Urothelial Carcinoma SLC15A1 0.06 0.01 blup 157 0.02 1.0e-02 0.2 6.5 1.1e-10 0.11 0.03 0.12 TRUE
28 The Cancer Genome Atlas Breast Invasive Carcinoma DOCK9 0.02 0.00 blup 213 0.01 1.7e-03 -2.3 -8.6 8.5e-18 -0.41 0.08 0.14 FALSE
29 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CLYBL 0.14 0.01 blup 225 0.04 9.1e-06 5.2 -5.8 6.2e-09 -0.02 0.13 0.03 FALSE
30 The Cancer Genome Atlas Pancreatic Adenocarcinoma CLYBL 0.26 0.04 lasso 4 0.05 3.2e-03 3.4 -5.8 6.5e-09 -0.01 0.03 0.11 FALSE
31 The Cancer Genome Atlas Thyroid Carcinoma DOCK9 0.06 0.02 blup 212 0.02 1.9e-03 10.2 -10.4 4.1e-25 -0.58 0.24 0.27 FALSE