Best TWAS P=2.19e-09 · Best GWAS P=1.24e-37 conditioned to 6.6e-33
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | PAQR5 | 0.22 | 0.02 | enet | 36 | 0.08 | 7.5e-04 | -3.0 | -6.0 | 2.2e-09 | -0.06 | 0.02 | 0.86 | TRUE |
| 2 | GTEx | Brain Cortex | LARP6 | 0.30 | -0.01 | enet | 6 | 0.03 | 5.1e-02 | -6.5 | 5.2 | 1.7e-07 | -0.17 | 0.09 | 0.06 | TRUE |
| 3 | GTEx | Cells Transformed fibroblasts | PAQR5 | 0.11 | 0.09 | lasso | 6 | 0.12 | 2.2e-09 | 5.7 | -5.7 | 1.5e-08 | -0.04 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Nerve Tibial | PAQR5 | 0.12 | 0.09 | lasso | 4 | 0.08 | 2.2e-06 | 5.7 | -5.3 | 1.3e-07 | -0.08 | 0.00 | 1.00 | FALSE |
| 5 | GTEx | Ovary | UACA | 0.31 | 0.11 | lasso | 6 | 0.15 | 1.5e-04 | 6.5 | -6.0 | 2.7e-09 | 0.10 | 0.08 | 0.14 | TRUE |
| 6 | GTEx | Skin Sun Exposed Lower leg | PAQR5 | 0.10 | 0.08 | lasso | 3 | 0.07 | 9.8e-07 | 5.7 | -5.7 | 1.2e-08 | -0.05 | 0.00 | 1.00 | FALSE |