Hub : Genes

LARP6

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0650 0.0200 4.9e-08 0.065 0.072 0.060 0.069 0.061 2.5e-08 4.2e-09 8.3e-08 7.6e-09 5.9e-08
2 GTEx Adipose Subcutaneous 0.0980 0.0360 5.0e-05 0.095 NA 0.059 NA 0.092 3.4e-08 NA 1.4e-05 NA 5.7e-08
3 GTEx Adipose Visceral Omentum 0.1200 0.0560 6.1e-03 0.014 NA 0.061 NA 0.038 6.3e-02 NA 4.2e-04 NA 4.6e-03
4 GTEx Brain Cerebellar Hemisphere 0.3500 0.0870 4.4e-05 0.347 NA 0.213 NA 0.313 9.5e-10 NA 3.7e-06 NA 8.7e-09
5 GTEx Brain Cerebellum 0.4170 0.0930 4.8e-07 0.326 NA 0.291 NA 0.302 2.2e-10 NA 3.0e-09 NA 1.3e-09
6 GTEx Brain Cortex 0.3040 0.0930 8.6e-04 -0.011 NA 0.030 NA 0.004 9.9e-01 NA 5.1e-02 NA 2.4e-01
7 GTEx Brain Hippocampus 0.2679 0.1031 4.4e-03 0.025 NA 0.006 NA 0.024 8.4e-02 NA 2.3e-01 NA 9.1e-02
8 GTEx Breast Mammary Tissue 0.1020 0.0350 2.4e-04 0.038 NA 0.040 NA 0.052 4.9e-03 NA 4.1e-03 NA 1.2e-03
9 GTEx Breast Mammary Tissue (Male) 0.0904 0.0643 7.9e-02 -0.006 NA -0.013 NA -0.012 4.8e-01 NA 8.6e-01 NA 7.8e-01
10 GTEx Breast Mammary Tissue (Female) 0.1204 0.0568 1.4e-02 -0.010 NA 0.008 NA -0.009 9.1e-01 NA 1.8e-01 NA 7.9e-01
11 GTEx Cells Transformed fibroblasts 0.1050 0.0460 2.1e-03 0.019 NA 0.041 NA 0.021 1.4e-02 NA 4.5e-04 NA 9.2e-03
12 GTEx Ovary 0.2570 0.0800 4.5e-04 0.134 NA 0.165 NA 0.164 3.6e-04 NA 7.5e-05 NA 7.9e-05
13 GTEx Pancreas 0.1270 0.0610 9.2e-03 0.062 NA 0.008 NA 0.032 1.3e-03 NA 1.4e-01 NA 1.7e-02
14 METSIM Adipose 0.1227 0.0294 1.1e-16 0.115 0.142 0.138 0.143 0.129 8.2e-17 1.5e-20 5.2e-20 9.5e-21 9.4e-19
15 TCGA Kidney Renal Clear Cell Carcinoma 0.0756 0.0450 1.2e-03 0.000 0.013 0.021 NA 0.017 3.5e-01 1.2e-02 1.6e-03 NA 4.4e-03
16 TCGA Kidney Renal Papillary Cell Carcinoma 0.1040 0.0560 2.4e-05 0.095 0.060 0.066 NA 0.085 4.3e-06 2.4e-04 1.2e-04 NA 1.4e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Bipolar Disorder (2018) 0.6 0.9 4.5 0.9 -1.2 -0.4 -0.2 -0.4 -1.0 0.8 -0.9 -1.1 -0.9 -0.3 -1.2 -0.0 -1.2 2.1 0.3
Bipolar Disorder or Schizophrenia 0.2 0.6 2.0 -0.1 -0.7 0.8 0.5 -0.4 -1.1 -0.6 -0.4 -0.9 -1.1 0.1 -1.2 -0.5 -1.4 0.4 -0.5
Depressed Affect (Nagel 2018) 0.7 1.5 3.1 1.1 -0.8 -0.8 1.7 -1.5 0.6 1.0 -1.8 -1.2 -1.4 -0.5 -1.8 -1.6 -1.0 -0.9 -0.9
Depression (Nagel 2018) 2.2 3.3 7.9 2.8 -1.2 -2.4 1.7 -2.0 2.0 2.7 -2.5 -1.6 -0.9 0.1 -1.7 -1.9 -1.5 -0.0 -1.1
Intelligence (Savage-Jansen 2018) 0.8 2.4 9.0 1.8 -0.9 -3.0 1.4 -1.2 0.3 2.6 -1.2 -1.0 -1.7 -1.2 -1.4 -1.4 -1.1 -1.1 -1.6
Neuroticism (Nagel 2018) 0.5 1.2 3.5 0.9 -0.2 -1.0 1.4 -1.5 0.9 0.9 -1.3 -0.7 -1.0 -0.0 -1.0 -1.4 -0.7 -1.9 -1.5
Schizophrenia (2018) 0.3 0.5 2.0 -0.9 0.0 1.4 0.8 -0.2 -0.7 -1.4 0.1 -0.3 -0.5 0.4 -0.6 -0.6 -0.8 -0.4 -0.9
Schizophrenia vs Biploar Disorder 2.0 2.7 9.9 -3.1 1.6 2.3 -1.4 1.9 0.5 -2.0 1.7 1.5 1.3 0.8 1.7 1.5 0.9 0.3 1.2
Worry (Nagel 2018) 0.4 0.8 2.7 0.5 -0.5 -0.5 1.0 -1.1 0.7 -0.1 -1.1 -0.7 -0.5 0.4 -0.8 -1.1 -1.3 -1.6 -1.1
Alzheimer’s Disease (in mother) 0.4 0.4 2.7 -0.2 0.1 0.2 0.5 0.0 -0.3 -0.1 -0.0 0.1 1.0 -1.6 0.6 -0.3 0.5 -1.4 -0.4
Alzheimer’s Disease (in father) 0.3 0.3 1.9 -0.0 -0.1 -0.6 -1.0 0.3 0.0 0.7 -0.3 -0.1 0.2 -1.4 -0.0 0.8 0.1 0.1 0.9
Alzheimer’s Disease (including proxy) 0.2 0.3 1.9 0.4 -0.3 -0.1 0.2 -0.3 -0.0 0.3 -0.6 -0.6 0.7 -1.4 0.1 -0.2 -0.3 -1.3 -0.4
Crohns Disease (2017) 0.4 1.0 3.6 -1.5 -0.0 0.9 -0.7 -0.1 1.9 -0.1 -0.0 -0.3 1.3 1.1 -0.0 0.5 0.8 1.9 1.0
Irritable Bowel Disease (IBD) 0.7 1.7 3.6 -1.8 0.8 1.5 -1.4 1.1 1.2 -0.8 1.2 0.6 1.9 0.6 0.7 1.2 1.2 1.9 1.6
Ulcerative Colitis (UC) 0.4 0.7 1.8 -0.9 0.8 0.9 -1.0 1.3 0.1 -0.4 1.1 0.7 1.0 -0.3 0.8 0.9 0.7 0.8 1.0
Major Depression (MDD) 2.1 2.6 4.5 2.0 -1.3 -1.7 2.1 -1.7 -0.0 1.0 -2.0 -1.8 -1.7 0.1 -1.4 -2.1 -1.9 -0.6 -1.8
Reaction Time 2.6 5.0 8.1 -1.9 2.8 1.8 -2.5 2.2 -1.4 -2.9 2.4 2.8 1.5 -0.8 2.5 2.5 2.1 1.9 2.7
Verbal and Numeric Reasoning (VNR) 0.6 1.4 4.5 0.9 -0.5 -2.1 0.8 -1.1 -0.0 2.1 -0.9 -0.5 -1.1 -0.3 -1.0 -1.0 -1.1 -1.9 -1.4
Breast Cancer 0.3 0.8 2.7 1.1 -0.4 -1.5 0.9 -0.8 -0.2 0.4 -1.2 -0.3 0.2 -1.7 -0.8 -1.0 -0.0 0.3 -1.4
Ovarian Cancer 1.2 1.6 6.1 0.5 -1.1 -1.6 1.7 -1.2 -0.8 0.3 -0.7 -1.0 -2.0 -0.2 -1.2 -1.6 -0.6 -0.6 -2.5
Prostate Cancer 1.7 2.3 5.5 0.4 -2.1 -2.3 1.0 -1.8 -0.5 0.2 -2.1 -1.9 -1.5 0.7 -2.2 -1.3 -2.2 0.6 -0.8
Age at First Birth 1.4 2.0 4.3 -1.6 1.4 0.9 -1.7 1.8 -0.8 -2.1 1.2 1.7 0.9 0.4 1.9 1.8 1.0 0.6 1.5
Bipolar Disorder (2011) 0.9 0.9 2.4 1.4 -1.2 -0.9 0.9 -0.9 -0.2 -0.1 -1.0 -1.1 -0.7 -0.4 -1.5 -0.8 -0.8 1.0 -0.8
Body Mass Index (BMI) (2010) 0.5 0.7 2.5 -1.0 0.1 1.6 0.7 0.2 1.0 -1.5 -0.0 -0.0 1.4 -1.1 0.3 -0.3 0.7 -0.1 -0.2
Coronary Artery Disease (CAD) 0.8 0.9 3.7 0.4 -0.5 -0.1 0.6 -0.8 -1.9 -1.6 -0.2 -0.9 -0.1 -1.0 -1.1 -0.3 -1.9 -0.2 -0.1
Crohns Disease (2012) 0.4 0.7 4.4 -0.2 -0.5 -0.1 -0.0 -0.5 2.1 1.0 -1.0 -0.8 0.9 1.6 -0.3 -0.2 0.1 0.8 -0.2
Mean Putamen Volume 0.1 0.1 0.5 0.0 0.2 -0.1 0.3 0.1 0.2 0.4 -0.4 -0.1 -0.1 -0.1 -0.2 -0.4 -0.2 0.7 -0.1
Fasting Glucose 1.3 1.6 3.3 1.8 -1.5 -0.9 1.5 -1.3 1.4 1.0 -1.2 -1.4 -1.0 1.3 -0.9 -1.8 -0.8 -0.1 -1.1
HbA1C 0.7 0.7 3.0 1.5 -0.7 -1.7 0.1 -0.4 1.4 0.3 -0.6 -1.0 -0.2 0.2 -0.1 -0.3 -0.9 1.1 0.7
HDL Cholesterol 0.4 0.6 4.2 0.4 -0.6 -0.3 -0.1 -0.7 -0.5 0.8 -0.2 -0.7 -2.0 1.4 -0.3 -0.1 -0.6 0.8 0.0
LDL Cholesterol 0.2 0.3 2.5 0.1 0.1 0.6 0.5 0.1 0.4 0.8 0.6 0.4 -0.3 0.4 0.3 -0.2 0.1 -1.6 -0.2
Lupus 0.4 0.6 2.4 -0.4 0.7 0.7 -0.7 0.7 -1.5 -0.9 0.9 0.7 -0.2 -0.2 0.7 0.8 0.1 1.1 0.6
Neuroticism (2016) 0.4 0.6 3.4 -0.2 1.3 -0.7 -0.0 0.4 -0.6 -0.8 0.8 1.1 -0.1 -0.2 0.5 0.1 0.9 -1.9 -0.7
Primary Biliary Cirrhosis 0.8 1.1 3.7 -1.2 1.0 1.9 -0.6 0.7 -0.9 -1.3 1.3 0.9 -0.1 0.3 0.5 0.7 1.5 1.2 1.0
Rheumatoid Arthritis 0.3 0.5 1.3 -0.9 0.5 1.1 -0.8 0.5 -0.2 0.0 0.8 0.9 0.9 -1.0 0.1 0.8 0.2 -0.1 0.7
Schizophrenia (2014) 0.2 0.4 2.2 -1.3 0.1 1.5 0.1 -0.1 -0.3 -1.3 0.4 -0.1 -0.2 0.6 -0.3 -0.0 -0.8 0.1 -0.2
Triglycerides 0.2 0.3 0.7 0.0 -0.3 0.0 0.8 -0.2 0.4 -0.7 -0.4 0.0 0.8 0.4 -0.6 -0.6 -0.2 -0.7 -0.6
Type 2 Diabetes (T2D) (2012) 0.9 1.1 4.7 -0.6 -0.0 2.2 -0.9 0.3 1.7 -0.3 0.8 -0.1 1.6 0.8 -0.0 1.0 0.5 1.5 0.9
Ulcerative Colitis 0.4 0.6 1.7 -0.7 0.7 0.6 -1.3 0.9 -0.7 -0.5 0.6 0.6 0.7 -0.1 0.4 1.2 0.3 1.0 1.3
Blood Eosinophil Count 1.1 8.7 20.4 -4.5 2.7 3.7 -2.4 2.8 4.1 -1.1 2.8 2.6 3.8 -0.2 2.0 2.5 3.7 2.0 3.1
Blood Platelet Count 0.1 1.4 4.9 -0.5 0.2 1.5 -1.0 0.9 -1.1 -1.9 0.6 0.5 0.7 -1.6 -0.7 1.0 -0.7 2.2 1.4
Blood Red Count 0.2 1.7 4.5 -0.8 1.8 1.3 -1.1 1.3 -0.6 -1.0 1.1 1.9 0.2 -0.8 2.1 1.2 2.0 0.4 1.3
Blood White Count 0.1 0.5 4.4 -0.6 0.5 0.4 0.7 0.1 0.1 -0.6 0.9 0.5 0.5 -2.1 0.1 -0.4 0.5 0.4 -0.1
Heel T-Score 0.5 3.6 27.4 4.1 0.0 -2.4 -0.1 -0.7 5.2 0.2 -0.8 -0.5 -0.8 0.4 0.9 -0.1 2.1 0.4 0.8
BMI 0.5 2.6 16.0 -0.6 1.8 2.2 0.7 0.6 4.0 -0.7 1.5 1.2 1.0 -1.0 1.2 -0.2 2.9 -0.2 0.7
Height 0.2 2.9 20.4 2.6 -0.9 -4.5 0.5 -1.0 -0.3 0.6 -1.5 -0.9 -1.5 -1.7 -0.4 -0.7 -2.3 -0.8 -1.2
Waist Hip Ratio (WHR) 0.5 2.4 5.3 -1.5 1.4 1.2 -2.2 2.2 -0.3 -1.4 1.8 1.5 2.3 -0.8 0.2 2.0 0.6 2.0 1.3
Systolic Blood Pressure 0.4 1.9 8.6 -0.7 0.7 -0.7 1.0 -0.1 -2.3 -2.9 0.2 0.8 1.5 -1.9 0.8 -0.7 0.1 -2.0 -1.4
Smoking Status 0.3 0.7 4.3 0.3 -0.8 -0.2 -0.5 -0.2 -0.8 -0.4 -0.8 -0.8 -0.2 1.2 -0.4 0.1 -1.0 2.1 0.7
Allergy or Eczema 0.8 2.1 7.2 -1.9 1.5 0.7 -1.2 0.7 0.3 -1.1 1.8 1.6 2.7 -1.5 1.1 1.3 2.2 -0.0 0.6
Cardiovascular Disease 0.7 2.2 7.6 -1.6 1.9 1.8 -0.0 0.9 -0.3 -2.8 1.8 1.6 1.6 -0.9 1.4 0.3 1.2 -2.0 -0.2
Hypothyroidism (self reported) 0.3 0.7 2.0 -0.7 0.8 0.4 -1.2 0.9 -0.3 -0.5 0.7 0.9 -0.2 -1.2 0.2 1.2 0.6 0.7 1.4
Respiratory disease 0.3 0.6 1.8 -0.6 0.6 0.7 0.5 0.7 0.0 -1.3 1.0 0.9 0.9 -0.7 0.7 -0.2 1.4 -0.9 -0.4
Type 2 Diabetes (T2D) (2018) 0.3 0.5 3.5 0.6 -0.5 -0.3 -0.1 -0.5 1.0 0.5 -0.6 -0.4 -0.9 1.9 -0.6 -0.0 -0.7 0.2 -0.1
Lung FEV1/FVC ratio 1.6 8.0 52.7 -6.7 1.2 1.5 -2.2 -0.9 -0.4 1.5 1.7 0.8 7.3 -0.0 0.9 1.5 -1.1 3.2 1.1
Lung FVC 0.3 1.8 5.6 1.9 -1.8 -1.3 0.4 -1.4 -0.8 0.1 -2.1 -1.7 -2.4 0.1 -1.5 -0.5 -0.9 0.4 0.7
Neuroticism 0.4 0.9 3.4 0.4 0.1 -1.3 1.0 -1.3 -0.5 -0.1 -0.7 -0.3 -1.2 -0.3 -0.5 -1.1 -0.7 -1.8 -1.4
Chronotype (morning person) 0.6 1.3 5.1 -1.8 0.8 0.6 -0.7 1.1 -2.3 -1.3 0.9 1.1 0.2 -2.1 0.7 0.9 0.2 -0.3 0.6
Hair Pigment 0.0 0.8 4.2 0.3 -0.5 -0.3 -1.4 -0.0 0.6 0.9 0.4 -0.5 0.7 1.0 0.1 1.1 -0.0 1.2 2.0
Tanning 0.0 0.3 1.4 1.1 0.0 -0.2 0.0 -0.4 0.9 0.3 -0.1 -0.2 -1.2 0.1 0.1 -0.1 0.4 -0.1 0.3
Hand grip strength (left) 0.7 1.8 4.8 1.2 -1.5 -1.7 1.5 -2.2 0.2 0.4 -2.0 -1.6 -0.7 -0.8 -1.3 -1.6 -1.5 0.3 -0.8
Number of treatments/medications taken 0.5 0.9 2.0 -1.2 1.4 0.3 -0.9 0.8 -0.8 -0.6 1.3 1.3 0.9 0.1 1.2 1.0 1.3 -0.5 0.7
Average weekly spirits intake 1.5 1.9 5.3 -1.0 1.7 1.7 -1.3 0.8 0.6 -1.5 1.5 1.5 0.5 -1.4 1.5 1.4 2.3 -0.1 1.5
Sensitivity / hurt feelings 0.3 0.5 2.8 -0.1 0.7 0.0 -0.1 0.4 -0.6 0.7 0.4 0.6 -0.8 1.6 0.7 0.3 0.3 -1.7 -0.6
Frequency of depressed mood in last 2 weeks 0.5 0.7 2.6 1.6 -0.3 -1.2 0.8 -0.9 0.2 0.7 -1.2 -0.6 0.5 0.4 -1.4 -0.9 -0.5 0.6 -0.5
Hearing difficulty/problems: Yes 0.1 0.2 0.7 -0.4 -0.4 -0.1 0.1 0.5 0.8 -0.5 -0.4 -0.4 0.5 0.3 -0.1 -0.1 -0.4 0.7 0.1
Relative age of first facial hair 0.2 0.4 3.2 -0.7 0.1 1.0 -0.0 -0.0 0.5 -0.8 0.3 0.0 0.5 1.8 0.0 0.0 -0.3 0.5 0.2
Other serious medical condition/disability diagnosed by doctor 0.2 0.3 2.8 0.4 0.1 0.4 -0.2 -0.1 1.7 1.0 0.2 -0.1 0.2 0.3 -0.3 0.2 0.3 0.5 -0.1
Ever used hormone-replacement therapy (HRT) 1.2 1.6 4.2 1.2 -1.6 -0.6 -0.7 0.0 1.2 2.1 -1.5 -1.7 -0.2 1.9 -1.0 0.3 -0.4 2.1 0.9
Ever had hysterectomy (womb removed) 0.5 0.5 1.1 -0.4 0.7 0.8 -0.4 1.0 -0.7 -1.0 1.0 0.9 0.5 0.3 0.5 0.6 1.0 -1.0 0.2
Systolic blood pressure, automated reading 0.4 1.2 5.9 -0.7 0.9 -0.0 0.4 0.3 -0.5 -1.8 0.5 0.8 1.7 -2.4 1.0 -0.1 1.2 -0.8 -1.0
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 1.4 -0.9 0.5 1.2 -0.6 0.1 -0.7 -0.2 0.5 0.4 -0.2 0.5 0.4 0.6 0.1 -0.7 0.5
Angina 0.6 0.8 5.5 1.2 -0.7 -0.8 -0.4 0.2 2.4 0.2 -0.8 -0.6 0.3 -0.6 -0.7 0.4 -0.2 0.9 1.1
Medication for hormone replacement therapy 0.4 0.5 2.9 0.5 -0.2 -0.6 -0.5 -0.9 1.7 0.9 -0.4 -0.4 -0.1 0.4 -0.3 0.3 0.9 0.7 0.8
Vitamin and mineral supplements 0.3 0.4 1.8 0.0 0.5 0.9 -0.5 -0.1 0.3 -0.6 0.5 0.6 0.5 -0.7 0.5 0.5 1.3 -1.0 0.3
Supplements: Zinc 0.9 1.0 2.4 0.2 -0.9 -0.9 1.1 -1.3 0.2 0.5 -1.5 -1.0 -1.0 1.2 -0.6 -1.2 -0.9 0.7 -1.1
Medication: Co-codamol 0.5 0.6 2.4 0.3 0.8 0.4 0.6 -0.5 1.3 0.1 0.3 0.5 1.3 -0.1 0.6 -0.4 1.6 -0.7 -0.7
Medication: Metformin 0.5 0.7 3.6 0.3 0.4 0.5 -0.8 0.4 1.9 1.0 0.6 0.5 -0.2 0.7 1.1 0.8 0.3 -1.2 0.6
Diabetes (father) 1.1 1.4 4.7 -0.2 -0.6 2.2 -1.4 -0.3 2.1 0.3 -0.0 -0.4 0.8 0.8 -0.3 1.2 0.3 2.0 2.0
Diabetes (mother) 0.4 0.5 2.4 0.5 0.4 0.1 0.8 -0.0 1.5 0.2 0.2 0.4 0.5 0.4 0.7 -0.7 1.1 -0.9 -1.2
Severe depression (siblings) 1.1 1.3 3.2 1.5 -0.9 -0.3 0.9 -1.1 1.8 1.8 -1.1 -1.0 -0.0 0.7 -1.4 -1.1 -0.8 -0.0 -1.5
Pack years adult smoking proportion 0.2 0.4 0.8 -0.7 0.7 0.4 0.5 0.3 0.5 -0.8 0.2 0.6 0.9 -0.9 0.4 -0.1 0.8 -0.6 0.4
Impedance of leg (right) 0.3 1.4 3.9 0.6 1.3 1.3 -2.0 1.5 0.1 1.0 1.4 1.0 -0.1 0.6 0.9 1.8 0.5 1.0 1.6
Leg fat-free mass (left) 0.6 3.4 9.1 1.7 -1.5 -1.8 3.0 -2.3 2.2 0.5 -1.8 -1.6 -0.8 0.1 -1.5 -2.9 -1.0 -1.4 -2.6
Trunk fat percentage 1.6 6.2 21.8 -0.8 3.6 3.1 -1.0 2.3 3.1 -0.7 3.2 3.1 1.7 -2.0 2.8 1.6 4.7 -0.3 1.2
Hand grip strength (right) 0.4 1.1 3.2 0.9 -1.3 -1.1 1.2 -1.8 0.3 0.6 -1.4 -1.2 -0.2 0.0 -0.7 -1.3 -1.2 0.4 -1.0
Townsend deprivation index at recruitment 0.4 0.5 4.9 -0.4 0.5 0.1 0.0 0.8 -1.1 -2.2 0.3 0.4 -0.4 0.1 -0.2 0.0 0.3 0.8 -0.6
Current tobacco smoking 1.6 2.6 9.3 -1.2 0.9 1.8 -1.9 1.6 -0.9 -1.7 1.2 0.9 1.4 1.2 0.9 1.8 1.3 3.1 2.3
Average weekly fortified wine intake 0.1 0.1 0.5 0.2 0.1 -0.6 -0.6 0.3 -0.6 -0.2 -0.1 -0.0 -0.1 -0.1 -0.1 0.5 0.7 0.4 0.0
Maternal smoking around birth 0.2 0.3 1.9 0.4 -0.6 -1.4 0.2 0.5 -0.6 -0.6 -0.7 -0.3 -0.7 -0.5 -0.2 -0.2 -0.6 -0.4 -0.1
Fed-up feelings 0.2 0.4 1.7 0.4 0.2 0.4 0.7 -0.4 1.0 -0.0 -0.0 -0.1 0.6 -0.9 -0.4 -0.6 0.2 -1.3 -0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 1.5 1.9 5.0 2.2 -1.0 -1.6 1.5 -1.2 1.9 1.9 -2.0 -1.3 -0.5 0.2 -1.2 -1.5 -0.8 -0.4 -1.1
Relative age voice broke 0.4 0.6 2.4 1.1 -0.7 -0.2 0.7 -0.6 -0.2 0.1 -0.7 -0.7 -0.5 1.6 -1.0 -0.7 -0.9 -0.1 -0.5
Taking other prescription medications 0.1 0.2 0.6 0.0 0.3 0.1 -0.7 0.5 -0.0 0.7 -0.0 0.2 0.1 0.8 0.1 0.6 0.3 0.5 0.7
Age when periods started (menarche) 0.1 0.3 2.1 -0.1 -0.4 -0.6 -0.3 0.1 -1.4 0.8 -0.1 -0.4 0.1 -0.5 0.3 0.3 -0.2 -0.2 -0.4
Bilateral oophorectomy (both ovaries removed) 2.5 2.9 5.8 -1.6 1.4 1.4 -2.1 2.0 0.6 -1.4 2.0 1.3 2.4 -0.5 1.5 2.1 2.1 2.0 1.5
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.9 13.2 0.6 1.2 0.1 -0.9 0.7 3.6 -0.5 1.5 1.2 1.1 0.4 1.8 1.0 1.8 0.4 1.0
Tinnitus: Yes, but not now, but have in the past 0.6 0.7 3.7 -0.3 0.0 -0.1 0.7 -0.4 0.9 -1.1 -0.3 -0.3 0.7 -1.9 -0.9 -0.7 1.3 0.2 -0.9
Qualifications: CSEs or equivalent 0.3 0.4 1.4 0.0 0.8 0.2 -0.5 0.4 0.3 0.8 0.5 0.8 0.2 0.3 1.0 0.4 1.2 -1.0 0.3
Serious illness, injury or assault to yourself 0.3 0.4 1.8 0.6 -0.4 -0.5 -0.8 0.2 1.3 0.5 -0.5 -0.4 -0.4 0.4 -0.0 0.7 0.0 1.0 0.9
High blood pressure 1.1 3.0 5.9 -2.1 2.4 1.4 -0.5 1.0 -0.7 -2.4 1.9 2.2 2.2 -2.3 1.7 0.7 2.1 -1.4 0.1
Hayfever, allergic rhinitis or eczema 0.7 1.6 3.7 -1.7 1.4 0.5 -0.9 1.0 -0.6 -1.7 1.4 1.5 1.9 -1.3 1.2 1.1 1.4 -0.4 0.2
Multivitamins +/- minerals 1.0 1.3 4.6 0.7 -1.0 -1.5 1.2 -0.3 -1.1 0.2 -1.0 -1.0 -1.6 1.1 -1.2 -1.2 -2.1 0.4 -0.9
Stomach or abdominal pain in last month 0.5 0.7 4.2 -1.4 0.6 1.4 -0.0 -0.1 0.1 -2.0 0.3 0.4 0.7 0.9 0.4 0.0 0.3 0.5 0.4
Supplements: Glucosamine 1.1 1.5 10.8 -0.3 -0.8 0.4 0.8 -0.7 -0.3 -1.7 -0.7 -1.0 -1.3 3.3 -0.3 -1.1 -1.8 0.5 -0.5
Diverticular disease/diverticulitis (self-reported) 1.6 1.9 4.0 1.7 -1.6 -0.6 1.9 -2.0 0.7 0.9 -1.4 -1.7 -1.5 1.0 -1.4 -1.9 -1.1 0.1 -0.6
Medication: Atenolol 0.7 0.9 2.5 -0.5 1.4 0.1 -0.6 0.5 -0.5 -0.7 1.0 1.3 0.5 -1.3 1.3 0.9 1.6 -0.5 0.8
Medication: Levothyroxine sodium 0.2 0.3 2.6 0.4 0.2 0.6 -0.0 -0.3 1.6 0.7 -0.3 0.1 -0.0 -0.5 -0.4 0.1 0.5 -0.2 0.2
Sitting height 0.6 4.4 11.3 2.6 -2.4 -3.4 2.0 -2.2 0.0 0.9 -2.7 -2.5 -2.3 0.8 -1.9 -2.2 -2.5 -0.9 -1.5
Chronic bronchitis/emphysema (father) 1.3 1.6 3.2 1.4 -1.0 -0.8 1.8 -1.8 0.2 1.1 -1.1 -0.9 -1.4 -0.5 -0.9 -1.7 -0.6 -1.8 -1.5
High blood pressure (mother) 0.6 0.9 2.3 0.9 -0.8 -0.3 1.5 -1.1 -0.3 0.7 -0.6 -0.9 -0.1 0.5 -1.0 -1.4 -1.2 -0.8 -1.5
Body mass index (BMI) 0.4 1.9 14.7 -0.1 1.0 1.1 1.2 -0.3 3.8 0.5 0.7 0.7 0.7 -0.8 0.9 -0.8 2.6 -0.7 -0.5
Impedance of leg (left) 0.5 2.5 6.6 -0.0 1.8 1.8 -2.6 2.2 -0.7 0.3 2.0 1.6 0.7 -0.5 1.4 2.4 0.8 1.3 2.1
Leg predicted mass (left) 0.7 3.6 9.2 1.8 -1.6 -1.9 3.0 -2.4 2.2 0.6 -1.9 -1.6 -0.9 0.1 -1.5 -2.9 -1.0 -1.4 -2.6
Trunk fat mass 0.7 3.0 11.2 -0.1 2.4 1.8 0.1 1.1 3.3 -0.2 2.0 1.9 1.2 -1.7 1.8 0.4 3.4 -0.5 0.2
Waist circumference 0.7 2.4 11.3 -0.6 2.0 1.3 0.1 1.0 3.4 -0.4 1.6 1.7 1.4 -1.4 1.4 0.3 2.9 0.1 0.0
Number of incorrect matches in round 0.5 0.8 2.5 0.7 -1.6 -0.9 0.5 -0.3 -0.5 0.1 -1.1 -1.4 -1.3 -0.3 -1.0 -0.6 -1.3 0.0 -0.5
Past tobacco smoking 2.8 5.2 9.9 -2.8 2.6 2.6 -2.0 3.1 0.7 -1.9 2.5 2.5 2.0 -1.0 2.5 2.3 3.1 0.5 2.1
Alcohol usually taken with meals 0.4 0.6 4.0 0.3 -0.1 -1.2 -0.0 -0.1 -2.0 -0.8 0.3 0.3 -1.6 0.3 0.2 -0.0 -0.5 -0.2 -0.3
Nervous feelings 0.4 0.8 2.5 -0.9 1.3 0.3 -0.6 0.9 -0.0 -0.5 0.7 1.1 0.8 -0.8 1.5 0.7 0.6 -1.6 0.3
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 2.4 0.9 -0.1 -1.0 0.8 -0.5 1.6 0.4 -1.2 -0.3 0.3 -0.3 -0.7 -0.8 0.2 0.3 -0.7
Hearing difficulty/problems with background noise 0.2 0.3 3.3 -0.3 -0.3 0.1 0.2 0.3 1.8 -0.1 -0.4 -0.3 0.6 0.6 -0.1 -0.2 0.2 0.8 0.1
Hair/balding pattern: Pattern 2 0.4 0.5 2.1 -0.0 0.1 1.2 1.2 -0.4 1.4 -0.5 0.2 -0.2 0.4 -0.1 -0.1 -0.9 0.1 -1.1 -1.1
Had menopause 0.1 0.1 0.4 -0.5 0.1 0.1 -0.1 0.5 -0.2 -0.4 0.2 0.1 0.4 0.6 0.1 0.1 0.4 0.2 0.0
Had other major operations 0.4 0.4 2.2 -0.2 -0.2 -1.5 -1.0 -0.1 -0.7 0.7 -0.2 -0.2 0.2 0.4 -0.5 0.6 -0.6 1.2 0.5
Forced vital capacity (FVC) 0.6 2.3 5.7 2.0 -2.1 -2.0 0.7 -1.2 -0.6 0.3 -2.0 -2.1 -2.0 0.2 -1.7 -0.8 -2.4 0.5 -0.2
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.0 9.2 1.8 -0.3 -1.2 0.1 -0.4 3.0 0.9 -0.2 -0.1 -0.4 0.7 0.8 0.0 0.4 -0.1 0.4
Ever unenthusiastic/disinterested for a whole week 0.1 0.2 1.1 0.5 0.2 -0.5 0.3 -0.1 0.3 0.5 -0.2 0.0 -0.3 -1.1 0.2 -0.2 0.8 -0.1 0.0
Qualifications: None of the above 0.9 1.8 4.6 -1.6 1.1 1.1 -0.3 1.6 0.8 -1.4 1.1 1.1 2.1 -2.2 1.5 0.8 1.9 -0.8 0.4
Financial difficulties in last 2 years 0.2 0.3 0.9 0.7 0.2 -0.8 0.2 -0.2 -0.9 0.9 -0.5 0.4 0.7 -0.6 0.2 -0.2 0.1 0.4 -0.4
Mouth/teeth dental problems 0.4 0.6 2.6 -0.2 -0.9 -0.5 0.7 -0.1 -1.1 -0.2 -0.9 -1.0 -0.7 0.7 -0.6 -0.7 -1.6 -0.7 -0.2
Heart attack 0.6 0.8 2.6 0.8 -0.3 -1.5 -1.4 0.3 1.6 0.3 -0.2 -0.2 0.2 -0.2 -0.0 1.2 -0.0 1.4 1.3
Allergy 0.8 1.9 3.7 1.6 -1.5 -0.5 0.9 -1.0 0.6 1.7 -1.8 -1.8 -1.9 1.6 -1.5 -1.1 -1.9 1.0 -0.3
Pain all over the body in last month 0.4 0.4 1.5 0.9 -0.6 -0.0 -0.0 -1.2 0.6 1.1 -0.4 -0.4 -0.7 0.2 -1.2 -0.1 0.0 0.1 -0.5
Diabetes (self-reported) 0.4 0.7 2.9 -0.3 0.0 0.5 -1.4 0.4 0.4 0.1 -0.0 0.4 0.6 1.7 0.3 1.1 -0.0 1.4 1.1
Hayfever/allergic rhinitis (self-reported) 2.0 2.6 9.2 -2.4 1.7 1.2 -1.3 1.8 0.3 -1.3 1.6 2.0 3.0 -0.7 1.8 1.3 1.8 -0.8 0.4
Medication: Ramipril 0.3 0.4 2.2 0.6 0.0 -1.2 -0.2 -0.2 0.8 -0.0 -0.2 0.3 0.2 -1.5 0.3 0.3 0.2 -0.7 0.6
Medication: Simvastatin 0.4 0.6 2.7 0.5 -0.6 -1.6 -0.0 -0.8 0.3 -0.5 -0.6 -0.6 -0.8 -1.2 -0.8 -0.2 -0.8 -0.7 -0.5
Fluid intelligence score 0.6 1.2 4.4 0.8 -0.4 -1.9 1.2 -1.2 -0.2 1.1 -0.6 -0.5 -0.8 0.1 -0.9 -1.3 -0.9 -1.3 -2.1
Illnesses of siblings 2.6 3.6 8.5 2.4 -1.8 -1.9 1.4 -1.7 -0.2 2.9 -2.2 -1.9 -2.8 0.9 -1.8 -1.6 -1.8 -2.0 -1.6
Neuroticism score 0.4 0.9 6.2 0.1 0.2 -0.4 1.3 -1.1 -0.3 -0.7 -0.4 -0.0 -0.8 0.1 -0.2 -1.2 -0.3 -2.5 -1.2
Weight 0.3 1.6 12.2 1.1 0.2 -0.4 1.9 -1.1 3.5 0.7 -0.3 -0.1 -0.1 -0.8 0.0 -1.6 1.1 -1.0 -1.4
Impedance of arm (right) 0.6 2.8 6.0 -0.7 2.0 1.9 -2.4 2.5 -2.0 -1.0 2.1 1.9 0.3 -0.7 1.1 2.4 1.2 0.8 1.5
Arm fat percentage (right) 1.0 3.8 16.0 -0.9 2.6 2.3 -0.2 1.2 3.3 -0.2 2.4 2.2 1.2 -1.4 2.1 0.7 4.0 -0.4 0.5
Trunk fat-free mass 1.5 8.7 15.9 2.9 -3.2 -4.0 3.8 -3.7 1.7 1.7 -3.5 -3.2 -1.7 0.3 -2.5 -3.9 -3.1 -1.3 -3.4
Hip circumference 0.5 2.2 16.8 0.6 1.2 0.5 1.5 -0.5 4.1 0.7 0.8 0.8 -0.1 -1.0 0.7 -1.0 2.6 -1.4 -1.1
Time employed in main current job 0.6 0.7 2.0 -0.3 1.1 -0.3 -1.4 0.1 -1.2 -1.1 0.6 1.1 0.1 -0.0 0.8 1.2 0.7 0.1 1.1
Alcohol intake versus 10 years previously 1.7 2.6 7.3 -1.9 1.6 1.7 -1.2 2.7 -0.1 -1.1 2.1 2.0 1.9 0.6 1.9 1.5 1.4 0.6 1.3
Father’s age at death 1.6 2.1 8.1 1.8 -1.4 -1.1 0.8 -1.5 0.9 2.8 -1.0 -1.3 -1.7 1.5 -1.0 -0.8 -1.0 -1.9 -1.0
Worrier / anxious feelings 0.2 0.4 3.0 0.3 -0.2 -0.2 0.5 -1.0 0.2 -0.8 -0.5 -0.4 -0.3 0.6 -0.3 -0.5 -0.4 -1.7 -0.1
Frequency of tiredness / lethargy in last 2 weeks 0.6 0.9 2.9 -0.5 1.6 -0.0 -0.7 0.5 0.7 0.2 0.8 1.7 1.5 -1.1 1.0 0.8 1.1 -0.6 0.8
Falls in the last year 1.9 2.5 8.4 2.2 -1.7 -1.6 1.2 -1.1 2.9 1.4 -2.2 -1.7 -1.0 1.0 -1.8 -1.2 -1.2 0.4 -1.0
Hair/balding pattern: Pattern 3 0.2 0.2 1.0 0.7 -0.3 -1.0 0.5 -0.2 -0.2 0.2 -0.1 -0.2 -0.9 0.5 -0.8 -0.4 -0.2 -0.3 -0.0
Number of live births 0.2 0.2 0.7 -0.4 -0.8 -0.3 0.1 0.2 -0.4 0.3 -0.8 -0.7 -0.5 0.6 -0.5 -0.1 -0.5 0.3 0.2
Forced expiratory volume in 1-second (FEV1) 0.7 2.4 8.2 0.7 -2.3 -1.8 0.5 -1.8 -0.1 1.1 -2.1 -2.3 -0.5 0.6 -1.9 -0.9 -2.9 1.0 -0.2
Pulse rate 1.9 3.3 6.7 -2.6 2.2 1.5 -2.1 1.5 -1.4 -1.9 2.0 2.1 0.2 0.5 2.3 2.1 1.6 0.8 2.2
Happiness 1.7 2.1 4.4 0.6 -1.8 -0.7 2.1 -1.5 0.5 0.1 -1.7 -1.8 -1.2 0.6 -1.9 -1.9 -1.2 -1.0 -2.0
Noisy workplace 1.7 2.1 9.3 -1.8 1.1 3.0 -1.1 1.7 -0.7 -3.0 1.4 1.3 0.7 0.0 0.4 1.2 0.5 -0.1 0.8
Qualifications: A levels/AS levels or equivalent 0.5 1.1 4.0 0.0 -1.2 -1.6 -0.5 -0.7 -1.2 -0.1 -0.8 -0.9 -0.2 1.4 -1.0 0.1 -1.7 2.0 0.3
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 1.2 -0.1 -0.3 -0.3 -0.2 0.6 0.8 -0.2 0.4 -0.3 0.2 0.1 0.0 0.3 -0.2 1.1 0.4
Mouth/teeth dental problems: Dentures 0.2 0.3 1.1 0.7 -0.4 -0.4 0.7 -0.2 0.7 1.1 0.1 0.0 -0.1 -0.6 0.6 -0.3 0.7 -0.5 -0.1
Asthma 0.5 0.9 3.0 -0.7 1.0 1.3 0.6 0.5 0.1 -0.4 1.3 1.2 1.2 -0.6 0.9 -0.3 1.7 -1.2 -0.7
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 3.7 -0.3 0.6 0.0 -0.2 -0.5 0.9 0.5 0.4 0.6 1.9 -0.7 0.3 0.1 1.2 -0.0 -0.4
Medication: Cholesterol lowering 0.7 1.0 2.8 -0.7 1.0 0.6 -1.0 0.8 -0.8 -1.5 1.1 1.1 1.1 -1.7 1.0 1.1 0.9 -0.6 0.7
Depression (self-reported) 0.5 0.6 1.0 0.5 -0.6 -0.1 0.9 -0.2 0.8 1.0 -1.0 -0.9 0.6 0.5 -1.0 -0.9 -1.0 0.9 -0.9
Medication: Lansoprazole 0.1 0.2 0.8 0.0 0.3 0.3 -0.0 0.9 0.5 0.3 0.3 0.3 0.4 0.0 0.6 0.2 0.4 -0.5 0.1
Prospective memory result 2.0 2.5 4.9 2.0 -2.1 -0.8 1.4 -0.8 1.5 0.4 -2.0 -2.2 -1.8 2.0 -2.0 -1.5 -1.5 0.5 -1.0
Lung cancer (father) 0.6 0.7 2.4 0.9 -0.8 -0.6 0.8 -1.5 0.7 1.5 -0.3 -1.0 0.3 0.9 -0.7 -1.0 -0.5 0.4 -0.2
Illnesses of mother 0.1 0.2 1.0 -0.1 0.1 0.1 -0.3 -0.1 1.0 0.2 0.1 0.1 -0.3 0.8 0.1 0.3 0.3 0.6 0.7
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 2.0 5.4 0.4 -2.0 -1.6 0.2 -1.7 0.8 1.8 -2.1 -2.1 -1.0 0.5 -1.4 -0.6 -2.3 1.0 0.2
Pulse wave Arterial Stiffness index 1.0 1.1 3.1 -0.2 1.2 0.2 -1.6 0.7 -0.2 -0.3 1.2 1.0 0.7 -1.4 0.9 1.6 1.8 0.4 1.3
Impedance of arm (left) 1.1 5.2 10.0 -1.3 2.9 2.8 -3.1 3.2 -1.7 -1.7 3.0 2.7 0.6 -0.6 1.9 3.1 2.0 0.7 2.3
Arm fat mass (right) 0.5 1.9 13.3 0.2 1.5 0.9 1.0 -0.0 3.7 0.2 1.1 1.1 0.6 -1.1 1.2 -0.6 2.7 -0.7 -0.5
Trunk predicted mass 1.5 8.8 16.4 2.9 -3.3 -4.0 3.7 -3.7 1.7 1.7 -3.5 -3.3 -1.8 0.4 -2.6 -3.9 -3.2 -1.2 -3.4
Standing height 0.5 4.9 12.8 3.1 -2.2 -3.6 2.0 -2.0 -0.2 0.8 -2.5 -2.2 -2.1 -0.0 -2.1 -2.2 -3.5 -0.9 -2.4
Length of working week for main job 0.6 0.6 2.5 -0.3 0.3 -0.1 -1.4 1.0 -0.2 0.3 0.6 0.3 1.6 0.2 0.8 1.3 0.7 0.4 0.8
Exposure to tobacco smoke at home 0.2 0.3 0.7 0.4 -0.0 -0.8 -0.8 0.5 -0.5 0.7 -0.0 -0.0 0.1 -0.5 0.1 0.7 -0.1 0.7 0.5
Breastfed as a baby 0.8 1.0 3.0 1.0 -1.7 -1.1 0.4 -0.9 0.1 0.7 -0.9 -1.6 -0.9 0.7 -1.5 -0.6 -1.2 0.6 -0.5
Tense / ‘highly strung’ 0.9 1.4 3.6 1.1 -1.0 -1.0 1.2 -1.3 1.2 0.4 -1.6 -1.1 -1.1 1.3 -1.9 -1.4 -0.9 -0.5 -1.4
Seen doctor (GP) for nerves, anxiety, tension or depression 3.3 5.0 8.9 2.4 -2.4 -1.3 2.8 -2.5 1.2 1.9 -2.4 -2.7 -0.9 2.3 -2.8 -3.0 -2.4 -0.4 -2.4
Hair/balding pattern: Pattern 4 1.6 4.0 10.0 -1.8 0.8 1.7 -3.2 1.5 -2.2 -1.3 1.9 1.4 2.9 0.1 1.8 2.8 0.8 2.3 2.7
Birth weight of first child 0.2 0.4 2.4 -0.1 -0.4 -1.5 0.1 0.6 0.4 -0.5 -0.7 -0.3 -0.4 -0.5 -0.3 -0.2 -0.9 0.8 -0.1
Peak expiratory flow (PEF) 0.3 0.8 3.2 -1.3 -0.6 0.8 -0.1 -1.0 1.0 1.1 -0.6 -1.0 1.8 0.7 -0.3 -0.1 -0.8 0.8 0.4
Pulse wave reflection index 0.4 0.5 2.4 1.5 -0.4 -1.6 0.3 -0.5 -0.1 0.8 -0.5 -0.5 -0.1 -0.9 -0.5 -0.3 -0.4 -0.8 -0.6
Ever highly irritable/argumentative for 2 days 0.8 0.9 3.8 0.7 -1.4 -0.9 -0.1 -0.1 0.5 0.0 -1.2 -1.5 -0.1 1.1 -1.2 -0.1 -0.7 1.9 0.8
Loud music exposure frequency 0.8 0.8 4.5 -0.4 -0.1 0.8 1.1 -0.3 0.8 -1.2 -0.3 -0.2 -0.9 2.1 -0.6 -1.1 -0.1 -1.2 -0.9
Qualifications: O levels/GCSEs or equivalent 1.0 1.5 4.7 1.7 -1.3 -0.9 0.3 -1.5 -0.8 1.8 -0.7 -1.5 -1.1 1.3 -1.0 -0.7 -2.2 1.0 -0.6
Mouth/teeth dental problems: Bleeding gums 1.1 1.4 4.2 -1.0 1.6 2.0 -1.2 0.9 -0.4 -1.1 1.2 1.5 1.1 -0.9 0.9 1.1 1.4 0.4 0.7
Blood clot in the leg (DVT) 0.6 0.8 5.6 0.9 -0.6 -0.4 0.5 -0.3 2.4 1.5 -0.1 -0.6 -0.7 -0.3 -0.8 -0.5 0.3 0.3 -0.8
Medication: Paracetamol 0.2 0.4 1.8 -0.1 -0.2 -1.3 0.0 -0.2 -1.4 -0.3 -0.2 0.1 0.5 -0.7 0.4 -0.0 -0.3 1.0 0.1
Headache pain in last month 0.3 0.5 2.1 -0.7 0.7 -0.4 -1.1 0.6 -1.5 -0.0 0.4 0.7 0.4 -0.2 0.8 0.9 0.7 0.3 0.8
Medication for cholesterol, blood pressure or diabetes 1.1 1.8 5.9 1.6 -1.6 -1.3 1.1 -1.0 1.1 2.4 -1.5 -1.7 -1.4 0.9 -1.0 -1.2 -1.2 0.4 -1.1
Glaucoma (self-reported) 0.6 0.7 4.0 -0.8 -0.2 1.4 -0.5 0.6 0.4 -0.7 0.0 -0.1 1.1 2.0 0.1 0.5 -0.1 1.1 0.2
Gout (self-reported) 2.3 3.1 7.7 -2.4 1.9 1.8 -1.2 2.2 -1.1 -2.8 1.8 2.0 1.7 -2.2 1.6 1.4 1.3 0.4 0.8
Hypothyroidism/myxoedema (self-reported) 0.1 0.3 0.6 0.0 0.7 0.1 -0.6 0.2 0.4 0.6 0.3 0.7 -0.8 -0.7 0.1 0.6 0.7 -0.3 0.6
Medication: Amlodipine 0.8 1.2 3.5 -0.8 1.0 -0.4 -0.1 1.3 -1.9 -1.6 1.5 1.3 0.4 -1.1 1.1 0.3 1.0 -1.0 -0.7
Medication: Ventolin 100micrograms inhaler 0.5 0.6 1.7 -0.9 1.1 0.6 -0.7 0.7 -0.2 -0.4 1.0 0.9 -0.5 -0.1 0.9 0.6 1.3 0.2 1.0
Birth weight 0.2 0.4 2.3 0.3 0.3 -0.4 1.0 0.3 -0.2 0.2 0.4 0.4 0.0 -0.4 0.3 -0.6 0.3 -1.5 -1.0
Chronic bronchitis/emphysema (mother) 0.6 0.7 2.2 0.7 -1.3 0.4 0.6 -0.5 0.4 -0.3 -0.6 -1.1 -1.5 1.3 -0.6 -0.7 -0.8 -0.1 -0.8
High blood pressure (siblings) 1.8 2.5 8.8 -2.4 1.6 0.7 -1.0 1.7 -0.4 -2.1 1.7 1.8 3.0 -0.5 1.3 1.1 1.1 1.6 1.2
Forced vital capacity (FVC), Best measure 0.7 2.6 7.1 2.1 -2.2 -2.1 0.7 -1.4 -0.0 0.9 -2.4 -2.2 -2.7 0.1 -1.5 -0.9 -2.2 0.2 -0.2
Body fat percentage 1.3 5.2 19.4 -0.7 3.2 2.9 -0.6 1.8 3.5 -0.2 2.9 2.7 1.5 -1.6 2.5 1.1 4.4 -0.3 1.0
Leg fat percentage (right) 0.7 2.5 18.4 0.4 1.7 1.6 0.7 -0.1 4.3 1.2 1.4 1.1 0.6 -0.1 1.4 -0.4 2.9 -0.5 -0.1
Arm fat-free mass (right) 0.9 4.4 10.0 2.0 -1.8 -2.6 3.2 -2.7 2.5 1.1 -2.3 -1.9 -0.8 -0.6 -1.4 -3.1 -1.2 -1.3 -2.6
Exposure to tobacco smoke outside home 0.8 1.1 10.2 1.1 -0.3 -0.0 0.6 -0.4 3.2 -0.3 -0.7 -0.7 -0.3 1.7 -1.0 -0.7 0.3 0.4 -0.2
Comparative body size at age 10 0.2 0.6 2.6 -0.9 1.0 1.6 0.3 0.6 1.2 -0.8 0.7 0.9 1.0 -0.7 0.2 -0.1 0.6 0.1 0.1
Number of full brothers 0.8 0.9 2.4 -0.6 0.5 0.2 -1.4 1.6 0.5 -0.9 0.9 0.6 0.3 -0.8 1.4 1.4 0.9 1.0 1.2
Worry too long after embarrassment 0.3 0.5 1.7 -1.1 0.8 0.7 -0.5 0.3 -0.8 -0.4 0.6 0.8 -0.1 0.7 1.3 0.7 0.9 -0.8 0.2
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.7 2.2 0.5 -0.7 -0.8 0.7 -0.8 1.5 0.2 -0.4 -0.6 0.9 0.3 -1.2 -0.7 -0.6 1.4 -0.8
Wheeze or whistling in the chest in last year 0.9 1.7 7.2 0.6 0.2 0.1 2.0 -0.6 2.7 1.0 -0.1 0.2 0.4 -0.5 -0.5 -1.6 1.9 -1.7 -2.0
Number of children fathered 1.0 1.2 2.7 -1.6 0.9 0.6 -1.0 1.3 -0.8 -1.4 1.4 0.9 1.6 0.0 1.1 0.9 1.1 1.0 0.0
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 2.8 1.2 0.2 -1.1 0.7 -0.9 0.9 1.7 -0.3 -0.1 0.1 -0.5 0.1 -0.8 0.6 -0.9 -1.3
Age at first live birth 0.5 0.9 5.8 0.4 0.2 0.8 0.7 -1.5 1.4 -0.0 0.4 0.1 -0.7 2.4 0.2 -0.8 -0.7 -0.8 -0.6
Pulse wave peak to peak time 1.2 1.4 3.5 0.4 -1.3 -0.4 1.8 -1.0 0.2 0.3 -1.3 -1.1 -0.9 1.3 -1.1 -1.8 -1.9 -0.7 -1.5
Health satisfaction 0.6 0.8 6.8 -0.1 0.0 0.1 0.1 -0.0 2.6 0.1 -0.5 -0.3 0.3 2.0 -0.4 -0.3 0.6 0.6 0.2
Shortness of breath walking on level ground 1.1 1.3 6.0 -0.6 1.2 1.7 0.2 0.7 2.5 -0.4 0.6 1.3 1.1 0.3 1.4 -0.0 1.7 -1.0 0.5
Qualifications: College or University degree 0.3 0.8 1.8 -1.3 0.4 1.1 -1.2 -0.2 -1.0 -1.3 0.9 0.7 0.5 1.2 -0.3 0.9 0.0 1.2 1.0
Eye problems/disorders: None of the above 0.3 0.3 3.5 0.1 0.4 0.1 -0.0 0.3 0.1 0.1 0.3 0.6 0.4 -1.9 0.4 0.2 0.6 -0.1 0.8
Mouth/teeth dental problems: Loose teeth 0.8 1.0 4.1 0.9 0.0 0.6 -1.1 -0.3 1.7 1.6 0.3 -0.2 0.5 1.0 0.3 0.9 -0.1 2.0 1.2
Emphysema/chronic bronchitis 1.2 1.4 9.7 0.4 -0.2 -3.1 0.7 -0.2 -0.6 -1.3 -0.5 -0.2 -0.5 -2.9 -0.1 -0.6 -0.1 0.3 -0.7
Medication for pain relief, constipation, heartburn 0.5 0.8 2.4 0.7 -0.8 0.0 1.1 -1.0 -0.1 0.7 -0.6 -1.0 -1.5 -0.5 -1.1 -1.1 -1.3 -0.7 -0.8
Neck or shoulder pain in last month 0.4 0.6 3.7 0.5 -0.2 0.0 -0.9 0.0 1.6 1.0 -0.0 -0.2 0.5 0.1 0.2 0.5 0.3 1.9 0.7
Medication: Blood pressure 0.8 1.4 4.1 -1.4 1.1 1.8 -0.8 0.9 -0.7 -2.0 1.4 1.1 1.6 -0.8 0.6 1.0 1.1 -0.1 1.0
Angina (self-reported) 0.6 0.8 5.3 1.3 -0.8 -0.8 -0.3 0.0 2.3 0.0 -1.0 -0.7 0.2 -0.5 -0.8 0.3 -0.2 0.9 1.0
Migraine (self-reported) 3.0 3.7 8.1 -2.9 2.1 1.5 -1.8 2.3 -1.8 -1.9 1.8 2.1 2.3 -0.6 2.4 1.7 2.2 0.6 1.5
Medication: Ibuprofen 0.3 0.4 2.1 -0.3 0.7 0.1 -0.2 -0.1 -0.0 0.3 0.7 0.7 1.4 -0.4 0.7 0.2 1.1 0.0 -0.2
Medication: Allopurinol 2.0 2.7 4.6 -2.1 2.1 1.6 -1.1 1.6 -0.9 -2.1 2.1 2.1 1.6 -1.9 1.6 1.3 1.4 0.3 1.0
Medication: Omeprazole 0.6 0.7 2.2 1.3 -0.5 -0.8 -0.1 -0.3 0.4 1.4 -0.9 -0.5 -1.5 0.9 -1.0 -0.0 -0.6 -0.4 -0.1
Medication: Seretide 50 evohaler 0.8 0.9 2.5 -0.0 1.1 0.8 0.3 0.3 1.2 1.3 0.8 0.7 1.3 -1.6 1.4 0.0 1.2 -0.4 -0.2
Mean time to correctly identify matches 4.1 7.8 14.2 -2.6 3.6 1.8 -2.5 2.9 -2.2 -3.5 3.2 3.8 2.5 -2.1 3.1 2.7 3.1 1.4 2.4
Heart disease (mother) 1.2 1.5 5.6 -0.9 1.2 0.2 -1.6 0.6 0.5 -1.0 0.9 1.2 2.4 -1.0 0.8 1.4 1.5 1.2 1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.6 1.9 -0.1 -0.8 0.7 1.2 -1.4 -0.2 -1.0 0.2 -0.5 -0.4 1.1 -0.8 -1.0 -0.2 0.8 -0.4
Whole body fat mass 0.5 2.1 11.0 0.1 1.8 1.4 0.5 0.5 3.3 0.1 1.5 1.4 0.9 -1.2 1.4 -0.1 2.8 -0.5 -0.1
Leg fat mass (right) 0.5 2.0 16.6 0.8 1.0 0.7 1.5 -0.6 4.1 0.9 0.8 0.6 0.3 -0.4 0.6 -1.1 2.2 -0.7 -1.0
Arm predicted mass (right) 0.8 3.9 9.2 1.9 -1.6 -2.5 3.0 -2.5 2.4 0.7 -2.2 -1.8 -0.6 -0.6 -1.3 -2.9 -1.4 -1.0 -2.5
Pulse rate, automated reading 0.9 2.9 6.1 -2.5 1.7 1.9 -1.6 1.0 -1.6 -1.7 2.3 2.0 1.3 -1.0 2.0 1.7 2.0 0.7 1.4
Alcohol intake frequency. 0.6 1.3 5.0 -0.9 1.2 -0.0 -0.7 1.5 -0.1 -0.3 1.2 1.4 0.3 -1.0 2.2 1.1 1.6 -1.0 1.2
Comparative height size at age 10 0.3 1.7 7.3 1.0 -1.5 -1.8 0.8 -1.0 -0.7 0.2 -1.7 -1.3 -0.8 1.1 -1.2 -1.1 -2.7 -0.7 -1.0
Number of full sisters 0.3 0.4 1.1 -0.1 -0.9 -0.4 0.3 -0.8 -0.4 1.0 -1.0 -0.8 0.3 -0.1 -1.0 -0.2 -0.4 -0.1 0.4
Suffer from ‘nerves’ 0.5 0.7 3.0 -0.6 0.7 1.2 1.2 0.1 0.2 -1.3 0.3 0.5 -0.1 0.7 0.1 -0.9 -0.3 -1.7 -1.3
Overall health rating 0.3 0.7 3.0 -0.1 0.1 1.2 0.4 0.2 1.7 0.2 0.3 0.1 1.3 1.7 0.2 -0.2 0.8 0.1 -0.6
Chest pain or discomfort 1.0 1.5 3.8 0.8 -0.8 -0.6 2.0 -1.1 1.8 0.4 -0.7 -0.8 -0.4 -1.5 -1.3 -1.8 -0.5 -1.0 -1.9
Had major operations 0.7 0.9 1.9 -1.3 1.1 0.4 -0.6 1.4 -0.0 -1.3 1.2 1.4 0.6 0.4 0.7 0.8 1.0 0.9 0.3
Age at last live birth 0.4 0.6 4.2 0.7 0.0 0.9 -0.0 -0.8 1.3 0.4 0.5 0.1 -0.7 2.0 0.2 -0.1 -0.6 -0.2 0.1
Family relationship satisfaction 0.8 0.9 2.5 1.2 -1.0 -1.1 0.6 -0.7 0.9 1.6 -1.6 -1.1 -0.7 0.7 -1.1 -0.8 -0.6 -0.3 -0.4
Leg pain on walking 3.3 4.1 11.8 2.1 -2.5 -0.9 1.6 -1.9 1.3 1.0 -2.2 -2.7 -1.5 3.4 -2.9 -2.0 -1.6 1.8 -1.2
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.7 2.2 -0.4 -0.1 0.6 -0.9 0.6 -0.8 0.3 0.1 0.2 1.5 -0.9 0.4 0.8 0.5 1.5 1.4
Commuting to job workplace: Car/motor vehicle 0.3 0.4 0.9 0.6 -1.0 0.0 0.5 -0.7 -0.9 0.9 -0.4 -0.7 0.3 0.8 -0.2 -0.5 -0.4 0.5 -0.6
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 0.9 -0.6 0.1 1.0 -0.4 0.7 0.6 -0.1 0.3 0.2 -0.6 0.7 -0.6 0.3 0.4 0.1 0.4
Medication: Aspirin 0.4 0.5 1.2 -0.2 0.5 -0.9 -0.9 0.8 -0.5 -1.1 0.2 0.7 0.3 1.0 0.8 0.8 0.3 0.4 0.7
Supplements: Vitamin C 0.5 0.6 3.7 0.1 -0.5 0.3 -0.4 -0.4 1.2 0.7 -0.4 -0.8 1.4 -0.2 -0.2 0.3 -0.5 1.9 0.6
Knee pain experienced in last month 0.2 0.3 1.1 -0.1 0.3 0.7 -0.4 1.0 -0.2 -0.6 0.4 0.3 0.5 0.8 0.6 0.3 0.6 1.0 -0.4
Hypertension (Self-reported) 0.7 1.8 4.6 -1.4 1.9 0.8 0.2 0.5 -0.3 -1.9 1.4 1.6 1.7 -2.1 1.2 0.1 1.7 -1.7 -0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.7 2.4 0.1 -0.3 0.0 -1.0 0.2 1.4 1.2 -0.9 -0.5 -0.3 0.1 0.2 0.7 -0.4 1.3 1.5
Illnesses of father: Heart disease 2.6 3.6 11.3 -1.5 1.6 0.9 -2.6 2.0 -1.3 -2.0 1.6 1.8 1.4 -1.3 1.1 2.4 1.2 3.4 2.4
Illnesses of siblings: Diabetes 1.9 2.3 3.9 -0.9 1.2 1.8 -1.9 1.2 0.8 -1.0 1.8 1.3 1.9 -0.1 2.0 1.9 1.8 1.4 1.8
Smoking status: Previous 3.2 4.7 9.2 2.6 -2.6 -2.4 2.0 -3.0 -0.8 1.8 -2.5 -2.3 -1.9 0.2 -2.1 -2.2 -2.9 -1.2 -2.4
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.3 5.1 2.3 -0.9 -1.2 0.4 -0.7 1.6 1.1 -0.7 -1.0 -1.5 1.0 -1.2 -0.5 -1.4 -0.2 -0.1
Whole body fat-free mass 1.1 6.2 13.1 2.3 -2.5 -3.1 3.6 -3.2 1.9 1.0 -2.9 -2.5 -1.3 0.0 -2.1 -3.6 -2.2 -1.5 -3.2
Leg fat-free mass (right) 0.5 2.7 7.5 1.4 -1.4 -1.7 2.7 -2.0 1.5 -0.0 -1.7 -1.4 -0.5 -0.5 -1.4 -2.6 -1.0 -1.3 -2.3
Arm fat percentage (left) 1.3 5.0 20.0 -1.1 3.1 2.8 -0.6 1.6 3.5 -0.6 2.7 2.6 1.5 -1.4 2.5 1.0 4.5 -0.3 0.9
Average weekly red wine intake 0.3 0.4 1.7 0.2 -0.7 -0.7 0.3 -0.6 -0.3 0.2 -0.6 -0.6 -1.3 0.4 -0.4 -0.4 -0.7 -1.2 -0.4
Handedness (chirality/laterality): Left-handed 2.0 2.5 4.6 -1.6 1.4 1.3 -2.1 1.8 1.0 -0.5 1.5 1.6 1.6 -0.9 1.4 2.1 2.0 1.3 2.1
Mood swings 0.4 0.7 2.3 0.6 0.0 0.0 1.5 -1.1 0.7 -0.6 -0.6 -0.3 -0.6 -0.1 -0.9 -1.4 0.2 -1.3 -1.2
Loneliness, isolation 0.1 0.1 0.8 0.2 0.4 -0.2 0.0 -0.0 0.1 0.9 -0.4 0.3 0.4 -0.3 0.0 -0.1 -0.0 0.9 0.2
Long-standing illness, disability or infirmity 0.2 0.3 1.8 0.7 -0.2 -0.4 0.6 -0.5 0.5 0.5 -0.3 -0.4 -0.4 -0.1 -0.5 -0.6 0.3 -0.4 -1.4
Ever had bowel cancer screening 0.8 0.9 2.9 0.8 0.1 -0.9 1.5 -1.0 0.5 1.0 -0.4 -0.2 -0.6 -0.1 -0.3 -1.3 0.9 -1.6 -1.7
Diabetes diagnosed by doctor 0.2 0.3 1.7 0.1 0.2 0.6 -0.9 0.0 0.7 0.4 0.1 0.3 0.2 1.3 0.5 0.7 -0.1 0.3 0.5
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 2.3 -0.8 0.0 0.4 -0.4 0.4 0.4 0.1 0.1 -0.0 -0.9 1.5 -0.2 0.2 0.4 0.3 0.4
Friendships satisfaction 0.2 0.3 2.6 -0.4 0.3 0.1 0.1 0.3 -1.6 -0.7 0.4 0.3 0.8 -0.4 -0.3 0.0 -0.0 -0.4 0.1
Qualifications: nursing, teaching 1.9 3.0 5.8 1.6 -2.3 -1.8 1.2 -2.0 -0.1 0.2 -1.9 -2.2 -1.9 2.1 -2.3 -1.6 -2.4 0.9 -0.9
Commuting to job workplace: Walk 0.3 0.3 1.1 0.6 0.1 0.4 0.7 -0.5 0.2 -0.8 0.1 -0.1 -0.5 1.1 -0.3 -0.6 -0.9 -0.4 -0.1
Eye problems/disorders: Cataract 0.4 0.4 1.2 0.4 -0.8 -0.3 1.0 -0.6 -0.2 0.5 -0.5 -0.8 -0.6 -0.2 -0.8 -0.9 -0.5 -0.4 -1.1
Mouth/teeth dental problems: Mouth ulcers 0.7 1.0 6.0 -0.6 1.1 -0.1 -1.1 0.7 2.5 0.5 0.8 0.9 0.7 0.8 0.5 0.9 1.2 1.2 0.9
Medication for cholesterol 0.4 0.6 3.0 -0.9 0.4 1.7 -0.0 1.0 -1.7 -0.2 1.0 0.5 0.2 0.6 0.1 0.2 -0.5 0.8 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.2 2.0 -0.2 -0.1 -0.7 0.1 -0.6 -1.4 -0.3 -0.2 -0.2 -0.7 -0.0 -0.4 -0.0 0.2 -0.1 0.1
Back pain experienced in last month 1.0 1.5 3.3 1.2 -0.9 -0.1 1.7 -1.5 1.2 0.3 -1.1 -1.1 -0.0 1.8 -1.2 -1.8 -1.4 -0.4 -1.7
Mineral and other dietary supplements 1.6 2.1 8.7 -0.4 1.3 0.5 -1.6 1.5 0.5 0.7 1.2 1.8 0.9 -3.0 0.9 1.8 2.6 -0.3 1.1
Breast cancer (self-reported) 0.3 0.3 1.0 -0.7 0.4 -0.4 -0.2 0.2 -1.0 -0.4 0.6 0.8 -0.8 -0.1 0.9 0.4 -0.3 -0.9 0.1
Asthma (self-reported) 0.3 0.6 2.1 -0.5 0.7 0.9 0.8 0.3 0.0 -0.3 1.0 1.0 0.9 -0.3 0.6 -0.5 1.4 -0.7 -0.9
Osteoporosis (self-reported) 4.2 5.2 11.7 1.7 -2.6 -2.3 1.8 -2.3 0.2 3.4 -2.2 -2.7 -2.3 2.1 -3.1 -2.2 -2.6 -0.4 -2.3
Osteoarthritis (self-reported) 1.8 2.4 6.5 1.5 -0.6 -0.5 1.9 -1.5 2.2 1.4 -0.5 -0.9 -1.4 2.4 -0.2 -1.8 -0.7 -2.5 -1.8
Medication: Aspirin 0.3 0.4 1.7 -0.0 0.2 -1.1 -0.5 0.7 -0.7 -1.3 -0.2 0.3 -0.3 1.2 0.4 0.3 0.1 0.3 0.4
Medication: Gliclazide 1.0 1.1 3.6 -0.1 0.5 -0.1 -1.8 0.5 0.8 0.7 0.4 0.5 0.6 1.0 1.8 1.6 0.3 1.3 1.9
Illnesses of father: None of the above (group 1) 0.6 0.7 1.5 1.1 -0.9 -0.8 0.7 -0.6 1.2 1.2 -1.0 -1.1 -0.6 0.2 -0.7 -0.8 -0.5 -0.4 -0.7
Smoking status: Current 1.5 2.3 7.7 -1.2 1.0 1.6 -1.9 1.5 -0.7 -1.4 1.2 0.9 1.3 1.4 0.9 1.7 1.4 2.8 2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 1.9 -0.6 -1.0 -0.5 -0.4 -1.0 0.1 0.2 -0.8 -0.9 0.4 -0.0 -0.7 0.3 -0.8 1.4 0.8
Whole body water mass 1.0 5.6 11.6 2.3 -2.4 -3.1 3.4 -3.0 1.8 1.0 -2.7 -2.4 -1.1 -0.1 -1.9 -3.4 -2.1 -1.3 -2.9
Leg predicted mass (right) 0.5 2.7 7.5 1.4 -1.4 -1.8 2.7 -2.0 1.5 0.0 -1.6 -1.4 -0.5 -0.4 -1.4 -2.6 -1.0 -1.3 -2.4
Arm fat mass (left) 0.5 2.1 13.3 0.0 1.6 1.1 0.7 0.2 3.6 0.1 1.2 1.2 0.7 -1.0 1.3 -0.4 2.9 -0.6 -0.4
Number of self-reported non-cancer illnesses 0.4 0.7 2.2 -0.7 0.9 0.6 -1.1 0.7 1.5 0.2 0.9 0.9 1.3 -0.2 0.5 0.9 1.0 -0.1 0.4
Average weekly champagne plus white wine intake 0.6 0.8 2.1 -1.2 1.5 -0.1 -0.9 0.8 -1.1 -0.6 1.2 1.5 0.4 -0.2 1.0 0.9 0.9 -0.1 0.4
Miserableness 0.5 0.9 2.3 0.8 -1.0 -0.2 0.2 -0.7 -0.3 1.2 -1.0 -1.1 -1.5 1.5 -1.2 -0.4 -1.4 0.6 0.5
Guilty feelings 0.5 0.7 2.6 0.3 0.5 -0.8 1.2 -1.1 -0.6 -0.2 -0.5 0.1 -0.4 -0.6 0.2 -1.1 0.3 -1.6 -1.5
Wears glasses or contact lenses 0.3 0.4 1.8 -0.2 -0.5 -0.3 0.4 0.3 -1.4 -1.3 -0.4 -0.2 -0.0 0.2 -0.2 -0.2 -1.0 -0.5 -0.4
Ever taken oral contraceptive pill 2.2 2.5 5.1 -1.9 2.2 1.2 -1.6 1.2 -0.9 -0.7 2.3 2.2 0.2 -0.6 2.2 1.8 1.8 -0.4 1.4
Hearing aid user 0.6 0.7 2.7 0.3 -0.4 -1.0 -0.7 -0.5 1.5 0.9 -0.7 -0.4 0.1 0.5 0.3 0.4 -0.5 1.3 1.6
Mother’s age at death 0.7 0.9 3.0 -0.7 0.8 1.4 -1.0 0.5 -0.3 -0.8 1.3 0.8 1.7 0.0 1.1 1.1 1.0 -0.4 0.5
Financial situation satisfaction 0.5 0.6 2.1 0.8 -0.6 -1.2 0.3 0.5 1.3 1.4 -1.3 -0.5 -0.5 -0.2 -0.6 -0.4 0.2 -0.2 -0.8
Tinnitus: Yes, now most or all of the time 0.2 0.2 1.5 -0.7 -0.1 0.0 -0.0 0.3 -1.2 -0.4 -0.3 -0.1 -0.0 -0.0 -0.4 -0.0 -0.1 0.7 0.3
Commuting to job workplace: Public transport 0.8 1.0 4.7 -0.2 0.2 1.0 -1.7 0.7 0.6 -0.9 0.4 0.1 0.2 -0.2 0.6 1.5 0.2 1.6 2.2
Eye problems/disorders: Glaucoma 1.7 2.0 5.0 -2.2 1.1 2.1 -1.8 1.6 0.2 -0.6 1.1 1.2 1.7 1.3 1.4 1.7 1.1 1.0 1.2
Medication: Blood pressure 0.3 0.5 1.9 -0.2 0.5 -1.2 0.2 -0.5 -0.3 -1.1 -0.2 0.5 -0.0 -1.2 0.3 -0.3 0.4 -1.4 -0.7
Pain type(s) experienced in last month: Hip pain 1.8 2.3 4.1 1.9 -1.6 -1.5 1.6 -2.0 1.0 1.2 -1.7 -1.5 -1.0 1.0 -1.2 -1.8 -1.7 -0.5 -2.0
Supplements: Fish oil (including cod liver oil) 0.5 0.6 3.5 0.0 -0.4 -0.3 0.7 -0.5 -0.8 -0.5 -0.3 -0.7 -0.3 1.9 -0.1 -0.7 -1.6 -0.2 -0.2
High cholesterol (Self-reported) 0.3 0.5 1.5 0.8 -0.1 -0.3 0.5 -0.3 -0.9 -1.2 -0.2 -0.1 -0.2 -1.2 0.2 -0.4 -0.4 -1.1 -1.1
Medication: Bendroflumethiazide 0.9 1.4 7.1 0.6 -0.1 -0.8 1.4 -1.4 -0.8 0.0 -0.7 -0.2 -0.4 -2.7 -0.2 -1.1 -0.1 -2.5 -1.3
Medication: Paracetamol 0.3 0.5 2.9 -0.8 0.5 -0.8 -0.2 0.3 -1.7 -0.8 0.5 0.8 0.6 -0.5 1.0 0.3 0.1 0.4 0.3
Medication: Lisinopril 0.3 0.4 2.1 -0.7 0.6 -0.3 0.0 -0.8 -1.4 -0.7 0.8 0.5 0.5 -0.9 -0.3 -0.0 0.3 -0.5 -0.1
Medication: Atorvastatin 0.3 0.3 1.2 0.5 0.2 0.4 -0.0 0.3 1.1 0.2 0.3 0.3 1.0 0.9 0.6 0.1 0.6 -0.9 0.4
Illnesses of father: High blood pressure 0.9 1.1 3.7 -0.6 0.3 0.2 1.9 -1.1 -1.4 -1.3 0.2 0.2 0.2 -0.7 -0.8 -1.5 -0.1 -1.9 -1.3
Alcohol drinker status: Never 0.9 1.0 3.0 -0.7 1.2 -0.0 -1.5 0.5 -0.3 0.0 1.3 1.3 0.2 0.0 1.7 1.5 1.3 -0.1 1.4
Ever smoked 2.6 4.6 8.3 2.9 -2.3 -2.0 2.1 -2.8 -0.3 2.0 -2.2 -2.3 -2.1 1.2 -2.4 -2.5 -2.8 -0.1 -1.9
Basal metabolic rate 0.8 4.6 10.7 2.2 -1.9 -2.5 3.3 -2.7 2.5 1.0 -2.2 -2.0 -1.0 -0.1 -1.6 -3.2 -1.4 -1.4 -2.7
Leg fat percentage (left) 0.7 2.4 15.7 0.1 1.8 1.8 0.3 0.3 4.0 0.8 1.5 1.3 1.0 -0.6 1.4 0.0 2.9 -0.2 0.2
Arm fat-free mass (left) 1.1 5.8 12.4 2.4 -2.3 -2.9 3.5 -3.1 2.5 1.5 -2.6 -2.3 -1.0 -0.0 -1.8 -3.5 -1.7 -1.4 -3.0
Number of operations (self-reported) 0.4 0.7 4.6 0.4 -1.1 -1.0 -0.8 -0.2 -0.4 -0.1 -0.1 -0.6 0.5 0.8 -0.7 0.6 -0.7 2.1 0.4
Average weekly beer plus cider intake 0.6 0.8 4.5 0.5 -0.2 1.3 0.3 0.0 2.1 0.4 0.4 -0.5 2.0 -0.7 0.1 -0.2 0.2 1.3 -0.1
Irritability 0.3 0.4 2.0 0.4 0.6 -0.7 0.5 -0.9 0.6 -0.4 0.2 0.4 0.4 -0.8 -0.4 -0.6 0.3 -1.4 -0.9
Risk taking 0.8 1.2 2.9 1.4 -1.5 -0.6 -0.3 -0.8 -0.5 1.4 -1.2 -1.6 -0.2 -0.9 -1.6 0.1 -0.8 1.7 -0.2
Ever had prostate specific antigen (PSA) test 2.7 3.1 10.9 1.3 -1.8 -0.8 2.5 -1.8 0.2 1.1 -1.2 -1.6 -2.1 1.3 -1.6 -2.4 -1.7 -1.4 -3.3
Fractured/broken bones in last 5 years 1.8 2.3 10.7 2.5 -1.2 -0.8 1.1 -1.3 1.6 3.3 -1.0 -1.2 -1.8 -0.2 -1.7 -1.2 -0.8 -0.0 -1.5
Age started oral contraceptive pill 0.5 0.6 2.9 0.5 -0.6 -0.6 0.8 -0.5 -1.7 -0.3 -0.3 -0.7 -0.3 0.5 -0.6 -0.8 -0.9 0.6 -1.1
Diastolic blood pressure, automated reading 0.7 2.1 8.1 -2.5 1.5 1.3 -0.5 0.0 0.1 -1.7 1.9 1.5 2.9 -1.0 1.4 0.7 1.5 0.0 0.4
Ever depressed for a whole week 0.4 0.5 1.2 0.8 -0.7 -1.0 1.1 -0.5 0.3 0.4 -0.6 -0.9 -0.3 -0.9 -0.5 -1.0 -0.4 -0.5 -1.1
Unable to work because of sickness or disability 0.2 0.3 0.8 0.5 0.9 -0.6 0.0 -0.3 0.6 0.9 -0.3 0.8 0.0 0.6 0.4 -0.0 0.6 -0.8 0.1
Commuting to job workplace: Cycle 0.9 1.1 3.1 0.6 -1.6 -0.0 0.4 -0.6 0.3 0.8 -1.4 -1.7 -1.2 1.0 -1.8 -0.6 -1.4 0.1 -1.0
Myopia 0.5 0.7 2.7 0.5 0.1 0.6 -0.8 0.6 1.3 -1.1 0.6 0.1 1.7 -0.1 0.9 0.8 0.3 1.1 -0.1
Vascular/heart problems diagnosed by doctor 0.8 2.2 5.3 1.7 -1.9 -1.1 0.5 -0.9 0.0 2.3 -1.4 -1.8 -2.0 2.3 -1.4 -0.7 -1.7 1.2 -0.3
Cholesterol lowering medication 1.6 2.4 4.7 2.0 -1.8 -2.1 1.2 -1.3 1.5 1.0 -2.2 -1.8 -2.1 0.2 -1.2 -1.4 -1.1 -0.5 -1.7
Medication: Omeprazole (e.g. Zanprol) 0.3 0.4 1.6 0.5 0.0 -0.2 -1.1 0.8 0.0 1.2 -0.1 0.2 -0.1 -0.4 -0.2 1.1 0.2 0.3 1.2
Pain experienced in last month 0.6 1.0 3.3 -1.6 0.7 0.4 -0.2 1.2 -1.8 -1.2 0.8 0.9 1.1 -1.1 1.1 0.5 0.4 -0.9 0.2
Supplements: Calcium 0.4 0.4 2.1 -0.2 0.3 0.1 -0.7 0.1 1.4 1.1 0.2 0.1 -0.1 0.9 -0.1 0.5 0.4 0.9 1.0
Basal cell carcinoma (self-reported) 1.1 1.3 2.5 1.2 -1.3 -0.7 1.1 -1.5 -0.2 1.1 -1.0 -1.2 -1.6 0.5 -0.9 -1.0 -1.3 -1.6 -0.7
Heart attack/myocardial infarction (self-reported) 0.6 0.8 2.4 0.9 -0.3 -1.5 -1.3 0.1 1.6 0.3 -0.4 -0.3 0.2 -0.2 -0.0 1.1 0.0 1.3 1.3
Deep venous thrombosis (DVT) (self-reported) 0.6 0.7 5.5 0.9 -0.6 -0.1 0.7 -0.3 2.3 1.2 -0.0 -0.6 -0.6 -0.3 -0.8 -0.7 0.3 0.1 -1.1
Heart disease (siblings) 0.1 0.1 1.4 0.2 -0.1 0.4 -0.3 0.1 1.2 -0.5 0.4 -0.1 0.1 -0.0 0.3 0.3 0.2 -0.0 0.1
Alcohol drinker status: Previous 0.5 0.5 2.3 -0.6 0.5 0.0 -0.4 0.6 -0.0 0.2 0.2 0.7 1.5 -1.5 0.4 0.6 0.8 0.1 1.0
Pack years of smoking 0.3 0.5 1.3 -0.7 0.9 0.2 0.5 0.3 0.7 -0.4 0.2 0.8 0.8 -1.1 0.5 -0.1 1.0 -1.1 0.2
Impedance of whole body 0.9 4.5 9.2 -0.8 2.8 2.6 -3.0 3.0 -1.1 -0.8 2.9 2.5 0.5 -0.5 1.9 3.0 1.8 0.9 2.2
Leg fat mass (left) 0.5 1.8 15.3 0.5 1.2 0.9 1.1 -0.2 3.9 0.7 0.9 0.8 0.7 -0.7 0.8 -0.8 2.3 -0.5 -0.6
Arm predicted mass (left) 1.2 6.1 12.0 2.5 -2.5 -3.1 3.5 -3.2 2.5 1.8 -2.8 -2.5 -1.3 0.0 -1.8 -3.5 -1.9 -1.2 -2.9