[Hub]/) : Traits : Heel T-Score : ← →

chr16:21,110,478-24,261,165

Best TWAS P=4.98e-18 · Best GWAS P=5.29e-18 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	EEF2K	0.14	0.23	lasso	7	0.23	2.2e-27	5.2	-5.3	1.2e-07	0.01	1.00	0.00	TRUE
2	GTEx	Adrenal Gland	USP31	0.11	0.04	lasso	2	0.01	1.7e-01	-8.4	8.5	2.2e-17	-0.80	0.04	0.78	FALSE
3	GTEx	Artery Aorta	RRN3P1	0.22	0.08	lasso	3	0.10	2.3e-06	6.4	-5.9	4.7e-09	0.00	0.26	0.68	FALSE
4	GTEx	Artery Tibial	NPIPB4	0.12	0.03	lasso	4	0.01	2.2e-02	6.4	6.6	3.8e-11	-0.01	0.04	0.12	TRUE
5	GTEx	Artery Tibial	RRN3P1	0.16	0.11	lasso	7	0.13	1.4e-10	6.4	-5.9	3.6e-09	0.00	0.23	0.77	TRUE
6	GTEx	Colon Transverse	RP11-645C24.5	0.41	0.12	enet	23	0.24	5.5e-12	2.1	-5.9	3.8e-09	-0.02	0.42	0.08	TRUE
7	GTEx	Esophagus Muscularis	UQCRC2	0.11	0.03	lasso	4	0.01	7.6e-02	6.4	-5.9	3.8e-09	0.02	0.08	0.16	FALSE
8	GTEx	Esophagus Muscularis	RRN3P1	0.28	0.08	enet	22	0.07	7.0e-05	4.3	-5.4	5.6e-08	-0.01	0.25	0.57	FALSE
9	GTEx	Esophagus Muscularis	RP11-645C24.5	0.51	0.23	enet	15	0.34	1.8e-21	2.1	-5.1	3.0e-07	-0.01	1.00	0.00	TRUE
10	GTEx	Lung	EARS2	0.10	0.05	enet	22	0.06	3.6e-05	-3.0	5.6	1.9e-08	-0.39	0.80	0.04	FALSE
11	GTEx	Muscle Skeletal	USP31	0.08	0.03	lasso	5	0.02	6.6e-03	-8.3	8.3	6.8e-17	-0.83	0.08	0.90	FALSE
12	GTEx	Muscle Skeletal	NPIPB4	0.14	0.01	lasso	8	0.02	1.7e-03	3.6	6.5	6.3e-11	-0.01	0.10	0.14	TRUE
13	GTEx	Nerve Tibial	USP31	0.12	0.01	enet	28	0.01	3.4e-02	-8.3	5.5	4.3e-08	-0.49	0.08	0.73	FALSE
14	GTEx	Ovary	RP11-105C19.1	0.29	0.05	lasso	4	0.04	4.1e-02	-5.2	5.4	5.4e-08	-0.41	0.04	0.45	FALSE
15	GTEx	Pituitary	RRN3P1	0.30	0.07	lasso	6	0.10	1.4e-03	3.0	-5.2	1.6e-07	0.02	0.07	0.10	FALSE
16	GTEx	Skin Not Sun Exposed Suprapubic	RP11-645C24.5	0.14	0.05	enet	13	0.10	3.2e-06	6.4	-5.2	2.3e-07	-0.04	0.20	0.56	FALSE
17	GTEx	Skin Sun Exposed Lower leg	RRN3P1	0.07	0.07	lasso	3	0.07	3.9e-06	6.4	-6.4	1.3e-10	0.02	0.19	0.62	FALSE
18	GTEx	Skin Sun Exposed Lower leg	RP11-645C24.5	0.30	0.06	lasso	10	0.21	2.2e-17	6.4	-5.5	3.9e-08	0.01	0.25	0.75	FALSE
19	GTEx	Testis	USP31	0.29	0.29	lasso	10	0.28	4.3e-13	-8.3	8.3	1.4e-16	-0.80	0.08	0.92	FALSE
20	GTEx	Testis	RP11-20G6.3	0.17	0.15	enet	9	0.15	2.7e-07	-7.9	8.7	5.0e-18	-0.84	0.04	0.95	TRUE
21	METSIM	Adipose	COG7	0.05	0.00	blup	479	0.04	2.0e-06	-8.1	5.5	3.9e-08	-0.41	0.14	0.64	FALSE
22	METSIM	Adipose	CTD-2270L9.4	0.03	0.01	blup	433	0.02	1.8e-03	-3.2	-5.7	1.4e-08	0.37	0.72	0.03	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	EEF2K	0.09	0.10	bslmm	171	0.09	1.5e-11	5.2	-5.2	1.5e-07	0.03	0.99	0.01	TRUE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	USP31	0.02	0.01	blup	81	0.01	9.0e-03	-8.0	6.3	3.9e-10	-0.54	0.04	0.39	FALSE