Best TWAS P=7.01e-14 · Best GWAS P=1.02e-13 conditioned to 0.922
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | NQO1 | 0.02 | 0.01 | blup | 39 | 0.01 | 0.0043 | -6.4 | -7.5 | 7.0e-14 | 0.88 | 0.01 | 0.86 | TRUE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | NQO1 | 0.06 | 0.04 | lasso | 3 | 0.01 | 0.0527 | -6.4 | -6.4 | 1.8e-10 | 0.80 | 0.01 | 0.79 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | NQO1 | 0.10 | 0.00 | enet | 21 | 0.02 | 0.0068 | 5.9 | -7.3 | 2.0e-13 | 0.51 | 0.01 | 0.35 | TRUE |