[Hub]/) : Traits : Heel T-Score : ← →

chr16:65,891,847-68,956,625

Best TWAS P=4.59e-36 · Best GWAS P=1.63e-40 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ATP6V0D1	0.10	0.12	lasso	8	0.11	2.4e-13	5.6	-5.9	4.0e-09	0.05	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	TPPP3	0.04	0.03	blup	222	0.03	2.0e-04	-2.6	7.0	2.3e-12	-0.69	0.16	0.62	TRUE
3	GTEx	Adipose Subcutaneous	RANBP10	0.05	0.01	lasso	6	0.01	3.5e-02	5.7	-5.7	1.2e-08	0.02	0.62	0.02	FALSE
4	GTEx	Adipose Visceral Omentum	C16orf86	0.10	0.00	enet	20	0.00	1.7e-01	5.6	-10.3	5.6e-25	0.58	0.04	0.64	FALSE
5	GTEx	Artery Aorta	RANBP10	0.11	0.01	enet	11	0.04	2.0e-03	-13.3	-9.3	1.1e-20	0.69	0.00	0.96	TRUE
6	GTEx	Artery Tibial	RANBP10	0.08	0.04	lasso	3	0.05	6.4e-05	5.1	-5.5	4.3e-08	0.08	0.84	0.01	FALSE
7	GTEx	Brain Cerebellum	KIAA0895L	0.47	0.06	enet	39	0.13	1.5e-04	-7.1	-6.2	6.0e-10	0.64	0.05	0.88	FALSE
8	GTEx	Brain Cortex	LRRC29	0.53	0.02	enet	20	0.12	3.2e-04	-13.3	-12.3	6.0e-35	0.73	0.01	0.91	FALSE
9	GTEx	Brain Hippocampus	PARD6A	0.46	0.00	lasso	7	0.02	8.8e-02	-2.9	-6.0	1.5e-09	0.09	0.03	0.07	FALSE
10	GTEx	Cells Transformed fibroblasts	RANBP10	0.10	0.01	enet	29	0.03	2.8e-03	4.7	-6.3	2.5e-10	0.04	0.07	0.04	FALSE
11	GTEx	Cells Transformed fibroblasts	NAE1	0.27	0.04	enet	42	0.03	1.4e-03	5.8	-7.2	5.6e-13	0.44	0.45	0.03	TRUE
12	GTEx	Esophagus Mucosa	NAE1	0.09	0.08	lasso	1	0.06	4.7e-05	5.7	-5.7	1.1e-08	0.07	0.72	0.02	FALSE
13	GTEx	Muscle Skeletal	C16orf86	0.05	0.04	lasso	2	0.03	4.0e-04	5.1	-5.2	2.2e-07	0.07	0.23	0.03	TRUE
14	GTEx	Nerve Tibial	RANBP10	0.15	0.14	lasso	7	0.13	1.8e-09	5.2	-5.3	1.0e-07	0.07	1.00	0.00	FALSE
15	GTEx	Pancreas	TPPP3	0.24	0.01	lasso	4	0.00	2.0e-01	-12.8	-12.5	4.6e-36	0.95	0.03	0.67	TRUE
16	GTEx	Spleen	ATP6V0D1	0.36	0.03	enet	9	0.07	6.0e-03	1.2	-6.0	2.2e-09	0.05	0.04	0.10	FALSE
17	GTEx	Testis	CKLF	0.35	0.19	lasso	8	0.17	4.8e-08	-4.7	5.2	1.8e-07	-0.08	0.97	0.00	TRUE
18	GTEx	Thyroid	RANBP10	0.08	0.03	lasso	4	0.03	2.2e-03	5.7	-5.7	9.3e-09	0.08	0.26	0.09	TRUE
19	GTEx	Thyroid	GFOD2	0.18	0.01	enet	16	0.02	1.1e-02	1.0	-5.4	7.8e-08	0.64	0.01	0.85	TRUE
20	GTEx	Thyroid	HSD11B2	0.15	0.07	enet	23	0.09	1.9e-07	5.6	6.9	6.7e-12	-0.19	1.00	0.00	FALSE
21	GTEx	Whole Blood	CMTM3	0.11	0.03	enet	38	0.05	1.8e-05	2.9	5.4	6.0e-08	-0.06	0.79	0.01	FALSE
22	GTEx	Whole Blood	ATP6V0D1	0.08	0.00	enet	13	0.00	3.6e-01	5.6	-7.8	4.2e-15	0.19	0.23	0.09	FALSE
23	GTEx	Whole Blood	DUS2	0.12	0.04	enet	10	0.05	4.0e-05	5.1	5.5	4.3e-08	-0.04	1.00	0.00	FALSE
24	METSIM	Adipose	ATP6V0D1	0.13	0.03	bslmm	210	0.07	3.5e-11	5.6	-8.3	8.5e-17	0.15	0.98	0.00	TRUE
25	METSIM	Adipose	CTCF	0.03	0.02	bslmm	222	0.01	3.4e-03	5.0	6.7	2.3e-11	-0.27	0.22	0.08	FALSE
26	METSIM	Adipose	LRRC36	0.10	0.07	lasso	24	0.10	1.6e-14	5.0	5.6	2.2e-08	-0.08	1.00	0.00	FALSE
27	METSIM	Adipose	NFATC3	0.03	0.00	blup	298	0.00	3.4e-01	-3.1	-5.8	7.2e-09	0.06	0.07	0.04	FALSE
28	METSIM	Adipose	RP11-61A14.3	0.04	0.00	blup	318	0.02	3.1e-04	5.2	6.7	3.0e-11	-0.08	0.57	0.02	TRUE
29	NTR	Blood	ATP6V0D1	0.02	0.01	bslmm	220	0.01	1.6e-04	5.6	-9.5	2.0e-21	0.33	0.53	0.01	FALSE
30	YFS	Blood	DYNC1LI2	0.03	0.02	blup	352	0.02	4.5e-07	5.7	-9.1	1.1e-19	0.27	1.00	0.00	FALSE
31	YFS	Blood	NAE1	0.04	0.03	bslmm	343	0.04	1.2e-11	5.1	-8.7	3.5e-18	0.30	1.00	0.00	FALSE
32	YFS	Blood	ZDHHC1	0.05	0.05	enet	26	0.05	1.8e-16	5.0	7.9	2.4e-15	-0.14	1.00	0.00	FALSE
33	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	B3GNT9	0.03	0.03	blup	26	0.02	1.3e-02	-7.9	-7.3	2.4e-13	0.70	0.05	0.45	FALSE
34	The Cancer Genome Atlas	Breast Invasive Carcinoma	ATP6V0D1	0.01	0.01	blup	33	0.01	7.1e-03	5.6	-5.7	9.6e-09	0.04	0.03	0.02	FALSE
35	The Cancer Genome Atlas	Breast Invasive Carcinoma	KCTD19	0.02	0.02	blup	29	0.03	3.5e-06	-4.7	-7.4	1.6e-13	0.74	0.33	0.61	FALSE
36	The Cancer Genome Atlas	Breast Invasive Carcinoma	SLC9A5	0.01	0.00	blup	30	0.01	1.1e-02	-6.9	-10.9	6.8e-28	0.83	0.02	0.45	FALSE
37	The Cancer Genome Atlas	Colon Adenocarcinoma	CENPT	0.05	0.05	enet	8	0.04	3.0e-03	5.6	5.5	3.4e-08	-0.05	0.01	0.90	FALSE
38	The Cancer Genome Atlas	Colon Adenocarcinoma	LRRC29	0.05	0.05	blup	33	0.05	5.4e-04	-7.0	5.3	1.4e-07	-0.59	0.36	0.09	FALSE
39	The Cancer Genome Atlas	Esophageal Carcinoma	CENPT	0.13	0.00	blup	33	0.00	3.5e-01	3.8	5.4	7.8e-08	0.04	0.01	0.32	FALSE
40	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CDH16	0.02	0.01	blup	37	0.01	3.4e-02	4.3	-6.9	4.3e-12	-0.04	0.02	0.72	FALSE
41	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CES2	0.03	0.01	blup	30	0.01	8.2e-03	5.7	-7.8	5.4e-15	-0.08	0.01	0.72	FALSE
42	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GFOD2	0.03	0.03	lasso	1	0.03	3.6e-04	5.6	-5.6	2.3e-08	0.07	0.01	0.98	FALSE
43	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	AGRP	0.06	0.00	enet	9	0.02	5.3e-03	4.9	5.2	2.4e-07	0.06	0.01	0.04	FALSE
44	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ATP6V0D1	0.04	0.06	lasso	4	0.05	1.4e-06	5.6	-5.7	1.5e-08	0.04	0.96	0.00	FALSE
45	The Cancer Genome Atlas	Brain Lower Grade Glioma	E2F4	0.11	0.01	blup	34	0.02	3.2e-03	-13.0	10.8	4.2e-27	-0.82	0.00	0.91	FALSE
46	The Cancer Genome Atlas	Lung Adenocarcinoma	ATP6V0D1	0.04	0.02	blup	33	0.03	4.7e-04	5.6	-6.9	7.0e-12	0.16	0.61	0.03	FALSE
47	The Cancer Genome Atlas	Lung Adenocarcinoma	RLTPR	0.03	0.02	lasso	3	0.02	1.8e-03	4.8	-5.3	1.1e-07	0.04	0.00	0.91	FALSE
48	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ATP6V0D1	0.04	0.00	enet	6	0.00	9.3e-02	5.6	-9.4	4.0e-21	0.46	0.02	0.28	FALSE
49	The Cancer Genome Atlas	Prostate Adenocarcinoma	CENPT	0.02	0.01	blup	33	0.01	6.9e-02	5.6	5.4	6.5e-08	0.04	0.01	0.83	FALSE
50	The Cancer Genome Atlas	Stomach Adenocarcinoma	FBXL8	0.04	0.01	enet	8	0.02	6.7e-03	-13.0	10.4	1.8e-25	-0.90	0.00	0.92	FALSE
51	The Cancer Genome Atlas	Thyroid Carcinoma	ATP6V0D1	0.04	0.01	enet	5	0.02	3.2e-03	2.5	-5.3	1.2e-07	-0.05	0.02	0.03	FALSE